Laryngeal Neuroendocrine Neoplasms: Analysis of 11 Cases in a Single-Center Study
Conclusion: The prognosis of LNEN is closely associated with the latest pathological classification and TNM staging. For a more detailed and specific clinical staging, further research involving multicenter large-scale data is needed.PMID:38717053 | DOI:10.1177/01455613241249270 (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - May 8, 2024 Category: ENT & OMF Authors: Jianlin Yue Qianqian Zhao Suyuan Sun Xinliang Pan Dayu Liu Source Type: research

Nomogram for predicting survival in T1 –T2 stage patients with supraglottic squamous cell carcinoma
ConclusionNomograms provide significant advantages in treatment decision making and diagnosis. Laryngectomy with partial laryngectomy is the most appropriate method for T1 –T2 SGSCC cases. However, radiotherapy can also be used. Thus, patients with T1–T2 SGSCC should be evaluated to determine if combination therapy is the optimal treatment approach. Nevertheless, further research is needed to understand the role of chemotherapy. Overall, this study identified nine key predictors of future outcomes, aiding healthcare professionals in assessing risks and making treatment decisions for T1–T2 SGSCC patients. (Source: Hormones and Cancer)
Source: Hormones and Cancer - May 8, 2024 Category: Cancer & Oncology Source Type: research

Cancers, Vol. 16, Pages 1804: Reconstruction of Partial Hypopharyngeal Defects following Total Laryngectomy: A Systematic Review and Meta-Analysis
Conclusion: Pectoralis myocutaneous flaps should not be the preferred method of reconstruction for most patients, considering their significantly higher rate of fistulas. In contrast, pectoralis major myofascial flaps yield promising results compared to free-flap reconstructions, warranting further investigation. (Source: Cancers)
Source: Cancers - May 8, 2024 Category: Cancer & Oncology Authors: Anthony M. Tonsbeek Roxy Leidelmeijer Caroline A. Hundepool Liron S. Duraku Mark J. W. Van der Oest Aniel Sewnaik Marc A. M. Mureau Tags: Systematic Review Source Type: research

Correction to: Dysphagia After Total Laryngectomy: An  Exploratory Study and Clinical Phase II Rehabilitation Trial with the Novel Swallowing Exercise Aid (SEA 2.0)
(Source: Dysphagia)
Source: Dysphagia - May 8, 2024 Category: Speech-Language Pathology Source Type: research

Reconstruction after Salvage Total Laryngectomy
Over recent decades, there has been a trend toward non-surgical or “organ preservation” therapy for advanced staged laryngeal cancers, but up to 1/3 of patients will see a lack of long-term treatment response. As a result of this paradigm shift, total laryngectomy is increasingly performed in the ‘salvage’ setting. Salvage total laryngectomy is associated w ith high rates of complications from impaired wound healing from prior chemotherapy and/or radiotherapy, and reconstructive techniques aim to decrease these complications. (Source: Operative Techniques in Otolaryngology - Head and Neck Surgery)
Source: Operative Techniques in Otolaryngology - Head and Neck Surgery - May 6, 2024 Category: ENT & OMF Authors: Nicholas Purdy, Vincent M Desiato Source Type: research

Interdisziplin äre Plastische und Rekonstruktive Chirurgie von Plattenepithelkarzinomen des Kopf-Hals-BereichsInterdisciplinary plastic and reconstructive surgery of head and neck squamous cell carcinomas
Laryngorhinootologie 2024; 103: S3-S27 DOI: 10.1055/a-2181-9088Das Plattenepithelkarzinom ist das häufigste Malignom im Bereich der Mundhöhle, des Pharynx und des Larynx. Auch im Zeitalter modernster medikamentöser Behandlungsverfahren ist und bleibt derzeit die radikale Resektion dieser Tumoren der therapeutische Goldstandard. Der mit der Operation verbundene Verlust anatomischer Strukturen verstärkt zwangsläufig die durch den Tumor selbst hervorgerufenen Funktionsstörungen. Dabei wird der Umfang der funktionellen Defizite maßgeblich vom Resektionsausmaß ...
Source: Laryngo- Rhino- Otologie - May 2, 2024 Category: ENT & OMF Authors: Remmert, S. Sack, F. Hasenberg, S. Lehnhardt, M. Steubing, Y. Puscz, F. Tags: Referat Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research

Laryngectomy plus postoperative radio(system)therapy versus primary radio(system) therapy for the treatment of locally advanced laryngeal and hypopharyngeal cancer - results from the University Clinical Cancer Registry Regensburg
CONCLUSIONS AND SIGNIFICANCE: The results of our study are consistent with the survival data reported in the literature. More detailed systematic data in clinical routine (e.g. relevant comorbidities) are required to ensure guideline-based recommended therapy.PMID:38664954 | DOI:10.1080/00016489.2024.2340086 (Source: Acta Oto-Laryngologica)
Source: Acta Oto-Laryngologica - April 26, 2024 Category: ENT & OMF Authors: Julia Maurer Julian Kuenzel Christopher Bohr Oliver Koelbl Karolina Mueller Michael Koller Oreste-Konrad Concato Veronika Vielsmeier Christoph Suess Source Type: research