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Light Flashes and other sensory illusions perceived in space travel and on ground, including proton- and heavy ion-therapies
Z Med Phys. 2023 Jul 14:S0939-3889(23)00081-8. doi: 10.1016/j.zemedi.2023.06.004. Online ahead of print.ABSTRACTMost of the astronauts experience visual illusions, apparent flashes of light (LF) in absence of light. The first reported observation of this phenomenon was in July 1969 by Buzz Aldrin, in the debriefing following the Apollo 11 mission. Several ground-based experiments in the 1970s tried to clarify the mechanisms behind these light flashes and to evaluate possible related risks. These works were supported by dedicated experiments in space on the following Apollo flights and in Low Earth Orbit (LEO). It was soon ...
Source: Zeitschrift fur Medizinische Physik - July 16, 2023 Category: Radiology Authors: L Narici Source Type: research

Evaluation of proton and carbon ion beam models in TReatment Planning for Particles 4D (TRiP4D) referring to a commercial treatment planning system
CONCLUSION: The absorbed dose between TRiP4D and SyngoRT were identical for both proton and carbon ion plans in the WP. Compared to SyngoRT, TRiP4D underestimated the target RBE-weighted dose; however more efficient in RBE-weighted dose calculation. Large variation for proton beam with range shifter was observed. TRiP4D will be used to evaluate doses delivered to moving targets. Uncertainties inherent to the 4D-dose reconstruction calculation are expected to be significantly larger than the dose errors reported here. For this reason, the residual differences between TRiP4D and SyngoRT observed in this study are considered ...
Source: Zeitschrift fur Medizinische Physik - July 16, 2023 Category: Radiology Authors: Yinxiangzi Sheng Lennart Volz Weiwei Wang Marco Durante Christian Graeff Source Type: research

Application of multi-method-multi-model inference to radiation related solid cancer excess risks models for astronaut risk assessment
Z Med Phys. 2023 Jul 8:S0939-3889(23)00080-6. doi: 10.1016/j.zemedi.2023.06.003. Online ahead of print.ABSTRACTThe impact of including model-averaged excess radiation risks (ER) into a measure of radiation attributed decrease of survival (RADS) for the outcome all solid cancer incidence and the impact on the uncertainties is demonstrated. It is shown that RADS applying weighted model averaged ER based on AIC weights result in smaller risk estimates with narrower 95% CI than RADS using ER based on BIC weights. Further a multi-method-multi-model inference approach is introduced that allows calculating one general RADS estima...
Source: Zeitschrift fur Medizinische Physik - July 10, 2023 Category: Radiology Authors: Luana Hafner Linda Walsh Source Type: research

Physical wedge as a tool for radiochromic film calibration
In this study the feasibility of using dose gradients produced by a physical wedge (PW) for RCF calibration was investigated. The aim was to establish an efficient and reproducible method for calibrating RCF using a PW. Film strips were used to capture the wedge dose profile for five different exposures and the acquired scans were processed to generate corresponding net optical density wedge profiles. The proposed method was compared to the benchmark calibration, following the guidelines for precise calibration using uniform dose fields. The results of the benchmark comparison presented in this paper showed that using a si...
Source: Zeitschrift fur Medizinische Physik - July 1, 2023 Category: Radiology Authors: Stevan Peci ć Milo š Vićić Ivan Bel ča Strahinja Stojadinovi ć Borko Nid žović Ljubomir Kurij Slobodan Devi ć Source Type: research