Novel Prostate Biopsy Technique Using Imaging Fusion in a Patient With Absent Rectum
A 70-year-old male with prior total colectomy for ulcerative colitis was referred for elevated prostate specific antigen (PSA) (8.01) with PIRADS 4 lesion on magnetic resonance imaging (MRI). Described is a novel technique using pre-operative multi-parametric prostate MRI and intraoperative computed tomography (CT) 3D/3D fusion for systematic and targeted prostate biopsy in a patient lacking a rectum. (Source: Urology)
Source: Urology - February 1, 2024 Category: Urology & Nephrology Authors: Mark D. Sawyer, Fernando J. Kim, Brett Wiesen, Granville L. Lloyd Tags: Surgical Techniques in Urology Source Type: research
Cover 1
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Source: Urology - February 1, 2024 Category: Urology & Nephrology Source Type: research
Aims and Scope
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Source: Urology - February 1, 2024 Category: Urology & Nephrology Source Type: research
Editorial Board
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Source: Urology - February 1, 2024 Category: Urology & Nephrology Source Type: research
Table of Contents
(Source: Urology)
Source: Urology - February 1, 2024 Category: Urology & Nephrology Source Type: research
Incidence of Ureteroenteric Anastomotic Strictures After Robotic vs Open Cystectomy in Adults
To synthesise the evidence comparing the incidence rates of UAS post-RARC vs Open Radical cystectomy (ORC) in adults undergoing cystectomy and to compare differential stricture rates between Extracorporeal and Intracorporeal urinary diversion (ECUD vs ICUD). The primary outcome was incidence rate of UAS post RARC vs ORC and the secondary outcome was incidence rate of UAS in RARC post ECUD vs ICUD. Review authors conducted comprehensive search for studies comparing RARC with ORC in terms of incidence of UAS. (Source: Urology)
Source: Urology - February 1, 2024 Category: Urology & Nephrology Authors: Dhruv Satya Sahni, Ajit Singh Oberoi, Srishti Ramsaha, Seamus Teahan, Simon Morton Tags: Review Article Source Type: research
Editorial comment
Quantitative tissue perfusion assessment with near-infrared fluorescence (NIRF) imaging using indocyanine green was first introduced for angiography in ophthalmology, and since has gained popularity amongst many surgical subspecialties including reconstructive urology. Use of tissue perfusion assessment in robotic ureteral reconstruction is well-established,1 and its use has been associated with decreased ureteroenteric stricture rates after ileal conduit creation.2 Due to its ability to provide objectivity to a historically subjective assessment, it is not surprising that it is being applied to other reconstructive cases. (Source: Urology)
Source: Urology - February 1, 2024 Category: Urology & Nephrology Authors: Alexandr M. Pinkhasov, Katherine T. Anderson Source Type: research
Novel Prostate Biopsy Technique Using Imaging Fusion in a Patient With Absent Rectum.
To describe a novel technique using pre-operative multi-parametric prostate MRI and intraoperative CT 3D/3D fusion for systematic and targeted prostate biopsy in a patient lacking a rectum. (Source: Urology)
Source: Urology - February 1, 2024 Category: Urology & Nephrology Authors: Mark D. Sawyer, Fernando J. Kim, Brett Wiesen, Granville L. Lloyd Source Type: research
Renal hypodysplasia/aplasia 3 caused by a rare variant of GREB1L with incomplete penetrance in a Chinese family
Renal agenesis (RA) represents the most severe form of congenital anomalies of the kidney and urinary tract (CAKUT). Bilateral renal agenesis (BRA) is almost invariably fatal at birth and has high genetic heterogeneity. Here we report on a Chinese family with two pregnancies affected by a prenatal form of BRA. Trio-WES was conducted to explore the underlying genetic cause and identified a novel nonsense variant (c.2621G>A: p. Trp874Ter) in the GREB1L gene. Based on previous research, pathogenic mutations in GREB1L can cause renal hypodysplasia/aplasia-3 (RHDA3) with autosomal dominant inheritance. (Source: Urology)
Source: Urology - February 1, 2024 Category: Urology & Nephrology Authors: Lihong Fan, Guosong Shen, Mingsong Liu, Yufei Liang, Juan Yao, Zhongying Ding, Zhi Li, Xiangping Feng, Jinghui Zhang, Xueping Shen Source Type: research
Incidence of ureteroenteric anastomotic strictures after robotic versus open cystectomy in adults
To synthesise the evidence comparing the incidence rates of UAS post-RARC vs ORC in adults undergoing cystectomy and to compare differential stricture rates between Extracorporeal and Intracorporeal urinary diversion (ECUD vs ICUD). (Source: Urology)
Source: Urology - February 1, 2024 Category: Urology & Nephrology Authors: Dhruv Satya Sahni, Ajit Singh Oberoi, Srishti Ramsaha, Seamus Teahan, Simon Morton Source Type: research
Malignancy in the public life: the story of Hubert Humphrey ’s bladder cancer
Hubert Horatio Humphrey was the 38th Vice President of the United States and a political leader on the national scene for 30 years. In 1967 he developed hematuria and many years later was diagnosed with bladder cancer. He was treated with radiation, surgical resection and chemotherapy but died in 1978 from metastatic transitional cell carcinoma. This manuscript reviews Humphrey ’s political career, his medical history and how information about his medical condition was used in the lay press. (Source: Urology)
Source: Urology - January 30, 2024 Category: Urology & Nephrology Authors: Kostantinos E. Morris, Theodore N. Pappas Source Type: research
Oxybutynin-Associated Cognitive Impairment: Evidence and Implications for Overactive Bladder Treatment
Anticholinergic medications have long been mainstays of overactive bladder (OAB) treatment. Oxybutynin, a first-generation anticholinergic, still accounts for more than half of all OAB medication prescriptions, despite associations with impaired memory and cognition, as well as mounting evidence that it may increase the risk of incident dementia. This review details the current literature regarding oxybutynin and cognition, including evidence from preclinical, clinical, and real-world studies that show that oxybutynin binds nonspecifically to muscarinic receptors in the brain and is associated with adverse cognitive outcom...
Source: Urology - January 29, 2024 Category: Urology & Nephrology Authors: Michael B. Chancellor, Alvaro Lucioni, David Staskin Source Type: research
Editorial Comment on “ Oxybutynin-associated Cognitive Impairment: Evidence and Implications for Overactive Bladder Treatment”
Oxybutynin, first introduced in 1975, has long been the pharmacologic mainstay of overactive bladder (OAB) treatment. It has demonstrated clinical success in addressing bothersome OAB and urge urinary incontinence symptoms and maintains a strong clinical foothold in managing neurogenic bladder in both pediatric and adult populations. However, a growing body of evidence as outlined in this review, has demonstrated that both short and long-term use may result in adverse cognitive outcomes, including impaired memory and increased dementia risk. (Source: Urology)
Source: Urology - January 27, 2024 Category: Urology & Nephrology Authors: Michelle E. Van Kuiken Tags: Editorial Comment Source Type: research
Editorial Comment for URL-D-23-01604R1: Oxybutynin-associated Cognitive Impairment: Evidence and Implications for Overactive Bladder Treatment
Oxybutynin, first introduced in 1975, has long been the pharmacologic mainstay of overactive bladder (OAB) treatment. It has demonstrated clinical success in addressing bothersome OAB and urge urinary incontinence symptoms and maintains a strong clinical foothold in managing neurogenic bladder in both pediatric and adult populations. However, a growing body of evidence as outlined in this review, has demonstrated that both short and long-term use may result in adverse cognitive outcomes, including impaired memory and increased dementia risk. (Source: Urology)
Source: Urology - January 27, 2024 Category: Urology & Nephrology Authors: Michelle E. Van Kuiken Tags: Editorial Comment Source Type: research
Editorial Comment for URL-D-23-01604R1
Oxybutynin, first introduced in 1975, has long been the pharmacologic mainstay of overactive bladder (OAB) treatment. It has demonstrated clinical success in addressing bothersome OAB and urge urinary incontinence symptoms and maintains a strong clinical foothold in managing neurogenic bladder in both pediatric and adult populations. However, a growing body of evidence as outlined in this review, has demonstrated that both short and long-term use may result in adverse cognitive outcomes, including impaired memory and increased dementia risk. (Source: Urology)
Source: Urology - January 27, 2024 Category: Urology & Nephrology Authors: Michelle E. Van Kuiken Source Type: research
