Pelvic Lymph Node Dissection at Radical Prostatectomy for Intermediate Risk Prostate Cancer: Assessing Utility and Nodal Metastases Within a Statewide Quality Improvement Consortium
: To assess which patients with intermediate-risk PCa would benefit from a pelvic lymph node dissection (PLND) across the Michigan Urological Surgery Improvement Collaborative, given the discrepancy in recommendations. AUA guidelines for localized prostate cancer (PCa) state that PLND is indicated for patients with unfavorable intermediate-risk and high-risk PCa and can be considered in favorable intermediate-risk patients. NCCN guidelines recommend PLND when risk for nodal disease is ≥2%. (Source: Urology)
Source: Urology - March 6, 2022 Category: Urology & Nephrology Authors: Joshua M. Kuperus, Conrad M. Tobert, Alice M. Semerjian, Ji Qi, Brian R. Lane, Michigan Urological Surgery Improvement Collaborative Source Type: research

Leeches and Caudal Analgesia after Replantation for Glans Amputation During Neonatal Circumcision
Neonatal circumcision is one of the most commonly performed surgical procedures in the world. As with all surgeries, it carries risks, including rare, but devastating complications, such as glans and/or penile shaft amputation. Complete glans amputation with successful replantation has been previously reported. Herein we report a case of complete amputation at the penile midshaft in a 28-day-old neonate with a unique approach to postoperative care including the use of leech therapy, topical heparin and caudal analgesia following successful microvascular replantation. (Source: Urology)
Source: Urology - March 6, 2022 Category: Urology & Nephrology Authors: Ahmad Mousa, Daniel T Keefe, Karen Wong, Kristen Davidge, Armando J Lorenzo, Joana Dos Santos Source Type: research

Virtual “Matchmaking”: Stakeholder Perspectives on the Future of the Urology Residency Match
: To examine stakeholder perspectives regarding the lack of in-person externships and transition to a virtual urology residency interview format. The unprecedented disruption from the COVID-19 pandemic forced an abrupt pivot to a “virtual” Urology Match for the 2021 cycle. We aim for our study to inform ongoing deliberations on the future of the Urology Match. (Source: Urology)
Source: Urology - March 6, 2022 Category: Urology & Nephrology Authors: Christopher J. Warren, Chanan R. Reitblat, Charles A. Ferreri, Nicholas W. Eyrich, Stephanie Daignault-Newton, Juan J. Andino, Hossein Sadeghi-Nejad, Raj S. Pruthi, Kate H. Kraft Tags: Rapid communication Source Type: research

Bladder management with chronic indwelling catheter is associated with elevated mortality in patients with spinal cord injury.
: To evaluate the impact of bladder management method, specifically chronic indwelling catheter (IndC), on survival in patients with spinal cord injury (SCI) in Spinal Cord Injury Model System (SCIMS) database. (Source: Urology)
Source: Urology - March 6, 2022 Category: Urology & Nephrology Authors: Nima Baradaran, Juan Peng, Marilly Palettas, YuYing Chen, Michael J. DeVivo, Jan M. Schwab Source Type: research

Nomogram predicting adverse pathology outcome on radical prostatectomy in low-risk prostate cancer men
: To develop and validate a prediction model to predict the risk of adverse pathology outcome on final pathology in low-risk PCa men. (Source: Urology)
Source: Urology - March 6, 2022 Category: Urology & Nephrology Authors: Jordan Nasri, Flora Barthe, Sneha Parekh, Parita Ratnani, Adriana M. Pedraza, Vinayak G. Wagaskar, Jonathan Olivier, Arnauld Villers, Ash Tewari Source Type: research

Ultrasound Correlates Highly with Cross Sectional Imaging for Small Renal Masses in a Contemporary Cohort
: To determine the correlation between ultrasound (US), cross-sectional imaging, and pathological renal mass sizes. (Source: Urology)
Source: Urology - March 6, 2022 Category: Urology & Nephrology Authors: Sandra Seo Young Kim, Rodney Breau, Ranjeeta Mallick, Anil Kapoor, Antonio Finelli, Frederic Pouliot, Simon Tanguay, Adrian Fairey, Bimal Bhindi, Luke Lavalee, Alan So, Ricardo Rendon Source Type: research

Editorial comment
Despite the relatively sparse number of randomized controlled trials (RCTs) in the field of male infertility, a disproportionately high number (no fewer than 50) of RCTs have examined the role of antioxidants for idiopathic male infertility. This topic has even been the subject of a Cochrane systematic review. Last updated in 2019,1 the Cochrane meta-analysis evaluated numerous antioxidants (carnitine, CoQ10, folate, magnesium, n-acetylcysteine, vitamin E, zinc, or a combination thereof) and showed increases in sperm motility and potentially in live birth rate with treatment. (Source: Urology)
Source: Urology - March 1, 2022 Category: Urology & Nephrology Authors: Scott D. Lundy Source Type: research

Editorial comment
Lai and colleagues present a nicely written retrospective analysis evaluating the relationship between prescription of abiraterone and enzalutamide to Medicare patients and pharmaceutical manufacturer payments to urologists and medical oncologists. During the years 2014- –2017 promotional payments were made to over one quarter of medical oncologists and one half of urologists who care for Medicare patients. Furthermore, increased payment levels were associated with increased prescription of abiraterone or enzalutamide. (Source: Urology)
Source: Urology - March 1, 2022 Category: Urology & Nephrology Authors: James T Kearns Source Type: research

Author reply
We agree that the adoption of paradigm-shifting oral targeted therapies is driven by multiple factors. With expanding indications for abiraterone and enzalutamide to earlier stages of the disease and the ongoing trials examining their use in localized prostate cancer (eg, NCT02799745), it is increasingly important to fully understand these factors. The commentary suggest the possibility of similarities between the trajectory of prescribing patterns for oral targeted therapies and those of gonadotropin-releasing hormone agonists in the 1990s. (Source: Urology)
Source: Urology - March 1, 2022 Category: Urology & Nephrology Authors: Lillian Y. Lai, Megan E.V. Caram, Vahakn B. Shahinian, Brent K. Hollenbeck Source Type: research

Editorial Comment
This prospective study of OnabotulinumtoxinA injection (BTX-A) bladder injections in patients with neurogenic bladder specifically from congenital spinal dysraphism (CSD), adds to the literature by assessing both patient-reported and more traditional urodynamic measurements, but also by taking an important look at the “high risk” population. This cohort of patients with characteristics worrisome for eventual bladder deterioration and kidney damage is small and heterogeneous as expected in CSD especially by the time they reach a transitional urologist, but is still meaningful. (Source: Urology)
Source: Urology - March 1, 2022 Category: Urology & Nephrology Authors: Diana K. Bowen Source Type: research

Editorial comment
The authors report on narcotic avoidance following robotic assisted laparoscopic radical cystectomy allowing for a routine 2 day postoperative hospital course. This is a single surgeon experience of 54 patients over 5 years. However, there is much more to their success in early discharge aside from just limiting narcotic usage. Routine use of alvimopan (once approved by the FDA) was administered starting in the preoperative period and continuously until bowel function returned. Additionally, a subcutaneous pump for long acting local anesthetic administration was used for up to 3 days at the time of surgery. (Source: Urology)
Source: Urology - March 1, 2022 Category: Urology & Nephrology Authors: Mitchell H. Bamberger Source Type: research

Editorial comment
Reconstruction of the posterior urethra following prostate cancer therapies such as radical prostatectomy or radiotherapy has traditionally been discouraged due to difficulties achieving an anastomosis, significant morbidity, including hemorrhage, rectal injury, ureteral injury and low success rates. However, there has been a growing experience of successful reconstruction of the posterior urethra using open, perineal, and abdominal perineal techniques.1 More recently the Trauma and Urologic Reconstructive Network of Surgeons reported encouraging results with the use of the robotic platform for reconstruction for vesicoure...
Source: Urology - March 1, 2022 Category: Urology & Nephrology Authors: Brian J. Flynn Source Type: research

Cover 1
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Source: Urology - March 1, 2022 Category: Urology & Nephrology Source Type: research

Aims and Scope
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Source: Urology - March 1, 2022 Category: Urology & Nephrology Source Type: research

Editorial Board
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Source: Urology - March 1, 2022 Category: Urology & Nephrology Source Type: research