Comparative study between the effect of mesenchymal stem cells microvesicles versus ozone on induced liver injury in adult male albino rats (Histological & amp; Immunohistochemical study)
Ultrastruct Pathol. 2023 Nov 23:1-13. doi: 10.1080/01913123.2023.2278627. Online ahead of print.ABSTRACTLiver disease accounts for approximately 2 million deaths er year worldwide. Liver fibrisis results from chronic injury to the liver. If not effectively treated in time, liver fibrosis may transform into liver cirrhosis. MVs are recognized as potential biomarkers and important theraputic tools for a wide sectrum of diseases. Medical ozone has the ability to protect the body against pathological conditions caused by oxidative stress. The influence of ozone and MVs on CCL4 induced liver fibrosis was investigated in this st...
Source: Ultrastructural Pathology - November 24, 2023 Category: Pathology Authors: Samar R Mohamed Samaa M El-Mahroky Sara Mohamed Abdel Aal Source Type: research
Comparative study between the effect of mesenchymal stem cells microvesicles versus ozone on induced liver injury in adult male albino rats (Histological & amp; Immunohistochemical study)
Ultrastruct Pathol. 2023 Nov 23:1-13. doi: 10.1080/01913123.2023.2278627. Online ahead of print.ABSTRACTLiver disease accounts for approximately 2 million deaths er year worldwide. Liver fibrisis results from chronic injury to the liver. If not effectively treated in time, liver fibrosis may transform into liver cirrhosis. MVs are recognized as potential biomarkers and important theraputic tools for a wide sectrum of diseases. Medical ozone has the ability to protect the body against pathological conditions caused by oxidative stress. The influence of ozone and MVs on CCL4 induced liver fibrosis was investigated in this st...
Source: Ultrastructural Pathology - November 24, 2023 Category: Pathology Authors: Samar R Mohamed Samaa M El-Mahroky Sara Mohamed Abdel Aal Source Type: research
Comparative study between the effect of mesenchymal stem cells microvesicles versus ozone on induced liver injury in adult male albino rats (Histological & amp; Immunohistochemical study)
Ultrastruct Pathol. 2023 Nov 23:1-13. doi: 10.1080/01913123.2023.2278627. Online ahead of print.ABSTRACTLiver disease accounts for approximately 2 million deaths er year worldwide. Liver fibrisis results from chronic injury to the liver. If not effectively treated in time, liver fibrosis may transform into liver cirrhosis. MVs are recognized as potential biomarkers and important theraputic tools for a wide sectrum of diseases. Medical ozone has the ability to protect the body against pathological conditions caused by oxidative stress. The influence of ozone and MVs on CCL4 induced liver fibrosis was investigated in this st...
Source: Ultrastructural Pathology - November 24, 2023 Category: Pathology Authors: Samar R Mohamed Samaa M El-Mahroky Sara Mohamed Abdel Aal Source Type: research
Investigation the effects of 2-aminoethoxydiphenyl borate (2-APB) on aminoglycoside nephrotoxicity
In conclusion, it has been considered that 2-APB can prevent gentamicin mediated nephrotoxicity with its anti-oxidant, anti-apoptotic and anti-inflammatory effects.PMID:37970647 | DOI:10.1080/01913123.2023.2278629 (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - November 16, 2023 Category: Pathology Authors: Özge Kendirlinan Yurdun Kuyucu Bilge G üzelel Ebru D ündar Yenilmez Abdullah Tuli G ülşah Seydaoğlu Ufuk Özgü Mete Source Type: research
Investigation the effects of 2-aminoethoxydiphenyl borate (2-APB) on aminoglycoside nephrotoxicity
In conclusion, it has been considered that 2-APB can prevent gentamicin mediated nephrotoxicity with its anti-oxidant, anti-apoptotic and anti-inflammatory effects.PMID:37970647 | DOI:10.1080/01913123.2023.2278629 (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - November 16, 2023 Category: Pathology Authors: Özge Kendirlinan Yurdun Kuyucu Bilge G üzelel Ebru D ündar Yenilmez Abdullah Tuli G ülşah Seydaoğlu Ufuk Özgü Mete Source Type: research
Investigation the effects of 2-aminoethoxydiphenyl borate (2-APB) on aminoglycoside nephrotoxicity
In conclusion, it has been considered that 2-APB can prevent gentamicin mediated nephrotoxicity with its anti-oxidant, anti-apoptotic and anti-inflammatory effects.PMID:37970647 | DOI:10.1080/01913123.2023.2278629 (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - November 16, 2023 Category: Pathology Authors: Özge Kendirlinan Yurdun Kuyucu Bilge G üzelel Ebru D ündar Yenilmez Abdullah Tuli G ülşah Seydaoğlu Ufuk Özgü Mete Source Type: research
Investigation the effects of 2-aminoethoxydiphenyl borate (2-APB) on aminoglycoside nephrotoxicity
In conclusion, it has been considered that 2-APB can prevent gentamicin mediated nephrotoxicity with its anti-oxidant, anti-apoptotic and anti-inflammatory effects.PMID:37970647 | DOI:10.1080/01913123.2023.2278629 (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - November 16, 2023 Category: Pathology Authors: Özge Kendirlinan Yurdun Kuyucu Bilge G üzelel Ebru D ündar Yenilmez Abdullah Tuli G ülşah Seydaoğlu Ufuk Özgü Mete Source Type: research
Investigation the effects of 2-aminoethoxydiphenyl borate (2-APB) on aminoglycoside nephrotoxicity
In conclusion, it has been considered that 2-APB can prevent gentamicin mediated nephrotoxicity with its anti-oxidant, anti-apoptotic and anti-inflammatory effects.PMID:37970647 | DOI:10.1080/01913123.2023.2278629 (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - November 16, 2023 Category: Pathology Authors: Özge Kendirlinan Yurdun Kuyucu Bilge G üzelel Ebru D ündar Yenilmez Abdullah Tuli G ülşah Seydaoğlu Ufuk Özgü Mete Source Type: research
Investigation the effects of 2-aminoethoxydiphenyl borate (2-APB) on aminoglycoside nephrotoxicity
In conclusion, it has been considered that 2-APB can prevent gentamicin mediated nephrotoxicity with its anti-oxidant, anti-apoptotic and anti-inflammatory effects.PMID:37970647 | DOI:10.1080/01913123.2023.2278629 (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - November 16, 2023 Category: Pathology Authors: Özge Kendirlinan Yurdun Kuyucu Bilge G üzelel Ebru D ündar Yenilmez Abdullah Tuli G ülşah Seydaoğlu Ufuk Özgü Mete Source Type: research
Investigation the effects of 2-aminoethoxydiphenyl borate (2-APB) on aminoglycoside nephrotoxicity
In conclusion, it has been considered that 2-APB can prevent gentamicin mediated nephrotoxicity with its anti-oxidant, anti-apoptotic and anti-inflammatory effects.PMID:37970647 | DOI:10.1080/01913123.2023.2278629 (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - November 16, 2023 Category: Pathology Authors: Özge Kendirlinan Yurdun Kuyucu Bilge G üzelel Ebru D ündar Yenilmez Abdullah Tuli G ülşah Seydaoğlu Ufuk Özgü Mete Source Type: research
The Sonic hedgehog pathway inhibitor GDC0449 induces autophagic death in human Medulloblastoma Daoy cells
In this study, we explore whether GDC0449 induces autophagy in the human MB cell lines. To investigate the ultrastructural pathology changes of GDC0449-treated Daoy and D283 cells, we employed Transmission Electron Microscopy (TEM) technology to identify the expression of autophagic vacuoles. Our results indicate that GDC0449 only increases autophagy in Daoy cells by increasing the LC3-II/LC3-I ratio and autophagosome formation.We also analyzed Beclin1, LC3, Bax, and Cleaved-caspase3 protein and mRNA expression levels of autophagic and apoptotic markers using fluorescence confocal microscopy, RT-PCR, and Western blot. We f...
Source: Ultrastructural Pathology - November 13, 2023 Category: Pathology Authors: Qi Zhang Wanjing Zou Longtao He Cuiping Zhang Ying Wang Source Type: research
The Sonic hedgehog pathway inhibitor GDC0449 induces autophagic death in human Medulloblastoma Daoy cells
In this study, we explore whether GDC0449 induces autophagy in the human MB cell lines. To investigate the ultrastructural pathology changes of GDC0449-treated Daoy and D283 cells, we employed Transmission Electron Microscopy (TEM) technology to identify the expression of autophagic vacuoles. Our results indicate that GDC0449 only increases autophagy in Daoy cells by increasing the LC3-II/LC3-I ratio and autophagosome formation.We also analyzed Beclin1, LC3, Bax, and Cleaved-caspase3 protein and mRNA expression levels of autophagic and apoptotic markers using fluorescence confocal microscopy, RT-PCR, and Western blot. We f...
Source: Ultrastructural Pathology - November 13, 2023 Category: Pathology Authors: Qi Zhang Wanjing Zou Longtao He Cuiping Zhang Ying Wang Source Type: research
The Sonic hedgehog pathway inhibitor GDC0449 induces autophagic death in human Medulloblastoma Daoy cells
In this study, we explore whether GDC0449 induces autophagy in the human MB cell lines. To investigate the ultrastructural pathology changes of GDC0449-treated Daoy and D283 cells, we employed Transmission Electron Microscopy (TEM) technology to identify the expression of autophagic vacuoles. Our results indicate that GDC0449 only increases autophagy in Daoy cells by increasing the LC3-II/LC3-I ratio and autophagosome formation.We also analyzed Beclin1, LC3, Bax, and Cleaved-caspase3 protein and mRNA expression levels of autophagic and apoptotic markers using fluorescence confocal microscopy, RT-PCR, and Western blot. We f...
Source: Ultrastructural Pathology - November 13, 2023 Category: Pathology Authors: Qi Zhang Wanjing Zou Longtao He Cuiping Zhang Ying Wang Source Type: research
The possible protective role of selenium on the visual cortex of adult albino rat on exposure to potassium dichromate
Ultrastruct Pathol. 2023 Nov 7:1-14. doi: 10.1080/01913123.2023.2259455. Online ahead of print.ABSTRACTThe visual cortex is very important in mammals for processing of visual information. Exposure to heavy metals such as potassium dichromate poses serious health threat to human beings. The aim of this work is to study the effect of potassium dichromate on the visual cortex of adult albino rat and also to identify the possibility of selenium as protective agent against toxicity of potassium dichromate. A total number of 40 adult albino rats weighting (200-250) gm were used. They divided into four groups: control group, pota...
Source: Ultrastructural Pathology - November 8, 2023 Category: Pathology Authors: Sally S Anwer Hala Mohamed Hassanin Source Type: research
The possible protective role of selenium on the visual cortex of adult albino rat on exposure to potassium dichromate
Ultrastruct Pathol. 2023 Nov 7:1-14. doi: 10.1080/01913123.2023.2259455. Online ahead of print.ABSTRACTThe visual cortex is very important in mammals for processing of visual information. Exposure to heavy metals such as potassium dichromate poses serious health threat to human beings. The aim of this work is to study the effect of potassium dichromate on the visual cortex of adult albino rat and also to identify the possibility of selenium as protective agent against toxicity of potassium dichromate. A total number of 40 adult albino rats weighting (200-250) gm were used. They divided into four groups: control group, pota...
Source: Ultrastructural Pathology - November 8, 2023 Category: Pathology Authors: Sally S Anwer Hala Mohamed Hassanin Source Type: research
