Morphologically and karyotypically atypical cells of 'normal' human bronchial epithelial cell line (Beas-2B)
In this study, atypical cells of the Beas-2B cell line in early passage culture were observed using light and electron microscopy, and the cells were further investigated for abnormal karyotypes by flow cytometry. This Beas-2B cell line could be morphologically categorized into two cell types, A and B. Type A contains a large nucleus and abundant cytoplasm (type A > 95%) and type B contains a small nucleus with dense and scarce cytoplasm (type B < 5%). Both atypical cell types had atypical and multilobed/multinucleated cells, including a high percentage (>30%) of mitotic figures, and were Ki-67 positive (100%). Ka...
Source: Ultrastructural Pathology - September 30, 2023 Category: Pathology Authors: Younsu Lee Young-Joon Ryu Source Type: research
Morphologically and karyotypically atypical cells of 'normal' human bronchial epithelial cell line (Beas-2B)
In this study, atypical cells of the Beas-2B cell line in early passage culture were observed using light and electron microscopy, and the cells were further investigated for abnormal karyotypes by flow cytometry. This Beas-2B cell line could be morphologically categorized into two cell types, A and B. Type A contains a large nucleus and abundant cytoplasm (type A > 95%) and type B contains a small nucleus with dense and scarce cytoplasm (type B < 5%). Both atypical cell types had atypical and multilobed/multinucleated cells, including a high percentage (>30%) of mitotic figures, and were Ki-67 positive (100%). Ka...
Source: Ultrastructural Pathology - September 30, 2023 Category: Pathology Authors: Younsu Lee Young-Joon Ryu Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
A closer look: ultrastructural evaluation of high-risk progression IgA nephropathy
Ultrastruct Pathol. 2023 Sep 12:1-9. doi: 10.1080/01913123.2023.2256836. Online ahead of print.ABSTRACTThis retrospective, cross-sectional study sought to examine the ultrastructural characteristics of glomerular lesions using Transmission Electron Microscopy (TEM) in IgA nephropathy (IgAN) and their relationship with the high risk of progression phenotype defined by KDIGO guideline as proteinuria ≥1 g/24 hours despite 3 months of optimized supportive care. We analyzed 81 IgAN patients (median age 41 years, 67% male, eGFR 43.8 mL/min, proteinuria 1.04 g/day); 42 (52%) of them had high risk of progression. There were no d...
Source: Ultrastructural Pathology - September 13, 2023 Category: Pathology Authors: George Terinte-Balcan Gabriel Stefan Source Type: research
