Morphometric, biochemical and histopathological effects of sofosbuvir (sovaldi) on testes of adult male albino rats
This study aimed to show how sofosbuvir affected the adult male albino rat testis. Forty adult male albino rats were used. The rats were equally split into two main groups (I and II), then each group subdivided into two subgroups (A and B). Each rat in group I (control) received 0.5 ml of distilled water every day for four weeks. Each rat in group II (sofosbuvir-treated) received 0.5 ml of distilled water containing 7.2 mg of sofosbuvir every day for four weeks. After four weeks (subgroups IA and IIA) and eight weeks (subgroups IB and IIB) of treatment, the rats were sacrificed. Histological, biochemical, and morphometric ...
Source: Ultrastructural Pathology - December 31, 2023 Category: Pathology Authors: Safaa M Hanafy Source Type: research
Morphometric, biochemical and histopathological effects of sofosbuvir (sovaldi) on testes of adult male albino rats
This study aimed to show how sofosbuvir affected the adult male albino rat testis. Forty adult male albino rats were used. The rats were equally split into two main groups (I and II), then each group subdivided into two subgroups (A and B). Each rat in group I (control) received 0.5 ml of distilled water every day for four weeks. Each rat in group II (sofosbuvir-treated) received 0.5 ml of distilled water containing 7.2 mg of sofosbuvir every day for four weeks. After four weeks (subgroups IA and IIA) and eight weeks (subgroups IB and IIB) of treatment, the rats were sacrificed. Histological, biochemical, and morphometric ...
Source: Ultrastructural Pathology - December 31, 2023 Category: Pathology Authors: Safaa M Hanafy Source Type: research
Morphometric, biochemical and histopathological effects of sofosbuvir (sovaldi) on testes of adult male albino rats
This study aimed to show how sofosbuvir affected the adult male albino rat testis. Forty adult male albino rats were used. The rats were equally split into two main groups (I and II), then each group subdivided into two subgroups (A and B). Each rat in group I (control) received 0.5 ml of distilled water every day for four weeks. Each rat in group II (sofosbuvir-treated) received 0.5 ml of distilled water containing 7.2 mg of sofosbuvir every day for four weeks. After four weeks (subgroups IA and IIA) and eight weeks (subgroups IB and IIB) of treatment, the rats were sacrificed. Histological, biochemical, and morphometric ...
Source: Ultrastructural Pathology - December 31, 2023 Category: Pathology Authors: Safaa M Hanafy Source Type: research
Morphometric, biochemical and histopathological effects of sofosbuvir (sovaldi) on testes of adult male albino rats
This study aimed to show how sofosbuvir affected the adult male albino rat testis. Forty adult male albino rats were used. The rats were equally split into two main groups (I and II), then each group subdivided into two subgroups (A and B). Each rat in group I (control) received 0.5 ml of distilled water every day for four weeks. Each rat in group II (sofosbuvir-treated) received 0.5 ml of distilled water containing 7.2 mg of sofosbuvir every day for four weeks. After four weeks (subgroups IA and IIA) and eight weeks (subgroups IB and IIB) of treatment, the rats were sacrificed. Histological, biochemical, and morphometric ...
Source: Ultrastructural Pathology - December 31, 2023 Category: Pathology Authors: Safaa M Hanafy Source Type: research
Myxoinflammatory fibroblastic sarcoma: ultrastructural study of 7 cases
Ultrastruct Pathol. 2023 Dec 21:1-5. doi: 10.1080/01913123.2023.2292559. Online ahead of print.ABSTRACTSince first described, several studies about Myxoinflammatory fibroblastic sarcomas (MIFS) have been published stating the clinicopathological, morphological and immunohistochemical features. However, the ultrastructural findings of these MIFS are limited. Thus, the objective of the present paper is to describe the ultrastructural characteristics of these type of tumors by utilizing tissue that was embedded in paraffin and submitted for immunohistochemistry.The tissue of seven different cases was obtained for ultrastructu...
Source: Ultrastructural Pathology - December 21, 2023 Category: Pathology Authors: Guillermo Ernesto Corredor-Alonso Claudia Haydee Sarai Caro-S ánchez Hugo Ricardo Dom ínguez-Malagón Source Type: research
Myxoinflammatory fibroblastic sarcoma: ultrastructural study of 7 cases
Ultrastruct Pathol. 2023 Dec 21:1-5. doi: 10.1080/01913123.2023.2292559. Online ahead of print.ABSTRACTSince first described, several studies about Myxoinflammatory fibroblastic sarcomas (MIFS) have been published stating the clinicopathological, morphological and immunohistochemical features. However, the ultrastructural findings of these MIFS are limited. Thus, the objective of the present paper is to describe the ultrastructural characteristics of these type of tumors by utilizing tissue that was embedded in paraffin and submitted for immunohistochemistry.The tissue of seven different cases was obtained for ultrastructu...
Source: Ultrastructural Pathology - December 21, 2023 Category: Pathology Authors: Guillermo Ernesto Corredor-Alonso Claudia Haydee Sarai Caro-S ánchez Hugo Ricardo Dom ínguez-Malagón Source Type: research
Myxoinflammatory fibroblastic sarcoma: ultrastructural study of 7 cases
Ultrastruct Pathol. 2023 Dec 21:1-5. doi: 10.1080/01913123.2023.2292559. Online ahead of print.ABSTRACTSince first described, several studies about Myxoinflammatory fibroblastic sarcomas (MIFS) have been published stating the clinicopathological, morphological and immunohistochemical features. However, the ultrastructural findings of these MIFS are limited. Thus, the objective of the present paper is to describe the ultrastructural characteristics of these type of tumors by utilizing tissue that was embedded in paraffin and submitted for immunohistochemistry.The tissue of seven different cases was obtained for ultrastructu...
Source: Ultrastructural Pathology - December 21, 2023 Category: Pathology Authors: Guillermo Ernesto Corredor-Alonso Claudia Haydee Sarai Caro-S ánchez Hugo Ricardo Dom ínguez-Malagón Source Type: research
Myxoinflammatory fibroblastic sarcoma: ultrastructural study of 7 cases
Ultrastruct Pathol. 2023 Dec 21:1-5. doi: 10.1080/01913123.2023.2292559. Online ahead of print.ABSTRACTSince first described, several studies about Myxoinflammatory fibroblastic sarcomas (MIFS) have been published stating the clinicopathological, morphological and immunohistochemical features. However, the ultrastructural findings of these MIFS are limited. Thus, the objective of the present paper is to describe the ultrastructural characteristics of these type of tumors by utilizing tissue that was embedded in paraffin and submitted for immunohistochemistry.The tissue of seven different cases was obtained for ultrastructu...
Source: Ultrastructural Pathology - December 21, 2023 Category: Pathology Authors: Guillermo Ernesto Corredor-Alonso Claudia Haydee Sarai Caro-S ánchez Hugo Ricardo Dom ínguez-Malagón Source Type: research
Myxoinflammatory fibroblastic sarcoma: ultrastructural study of 7 cases
Ultrastruct Pathol. 2023 Dec 21:1-5. doi: 10.1080/01913123.2023.2292559. Online ahead of print.ABSTRACTSince first described, several studies about Myxoinflammatory fibroblastic sarcomas (MIFS) have been published stating the clinicopathological, morphological and immunohistochemical features. However, the ultrastructural findings of these MIFS are limited. Thus, the objective of the present paper is to describe the ultrastructural characteristics of these type of tumors by utilizing tissue that was embedded in paraffin and submitted for immunohistochemistry.The tissue of seven different cases was obtained for ultrastructu...
Source: Ultrastructural Pathology - December 21, 2023 Category: Pathology Authors: Guillermo Ernesto Corredor-Alonso Claudia Haydee Sarai Caro-S ánchez Hugo Ricardo Dom ínguez-Malagón Source Type: research
Myxoinflammatory fibroblastic sarcoma: ultrastructural study of 7 cases
Ultrastruct Pathol. 2023 Dec 21:1-5. doi: 10.1080/01913123.2023.2292559. Online ahead of print.ABSTRACTSince first described, several studies about Myxoinflammatory fibroblastic sarcomas (MIFS) have been published stating the clinicopathological, morphological and immunohistochemical features. However, the ultrastructural findings of these MIFS are limited. Thus, the objective of the present paper is to describe the ultrastructural characteristics of these type of tumors by utilizing tissue that was embedded in paraffin and submitted for immunohistochemistry.The tissue of seven different cases was obtained for ultrastructu...
Source: Ultrastructural Pathology - December 21, 2023 Category: Pathology Authors: Guillermo Ernesto Corredor-Alonso Claudia Haydee Sarai Caro-S ánchez Hugo Ricardo Dom ínguez-Malagón Source Type: research
Myxoinflammatory fibroblastic sarcoma: ultrastructural study of 7 cases
Ultrastruct Pathol. 2023 Dec 21:1-5. doi: 10.1080/01913123.2023.2292559. Online ahead of print.ABSTRACTSince first described, several studies about Myxoinflammatory fibroblastic sarcomas (MIFS) have been published stating the clinicopathological, morphological and immunohistochemical features. However, the ultrastructural findings of these MIFS are limited. Thus, the objective of the present paper is to describe the ultrastructural characteristics of these type of tumors by utilizing tissue that was embedded in paraffin and submitted for immunohistochemistry.The tissue of seven different cases was obtained for ultrastructu...
Source: Ultrastructural Pathology - December 21, 2023 Category: Pathology Authors: Guillermo Ernesto Corredor-Alonso Claudia Haydee Sarai Caro-S ánchez Hugo Ricardo Dom ínguez-Malagón Source Type: research
Myxoinflammatory fibroblastic sarcoma: ultrastructural study of 7 cases
Ultrastruct Pathol. 2023 Dec 21:1-5. doi: 10.1080/01913123.2023.2292559. Online ahead of print.ABSTRACTSince first described, several studies about Myxoinflammatory fibroblastic sarcomas (MIFS) have been published stating the clinicopathological, morphological and immunohistochemical features. However, the ultrastructural findings of these MIFS are limited. Thus, the objective of the present paper is to describe the ultrastructural characteristics of these type of tumors by utilizing tissue that was embedded in paraffin and submitted for immunohistochemistry.The tissue of seven different cases was obtained for ultrastructu...
Source: Ultrastructural Pathology - December 21, 2023 Category: Pathology Authors: Guillermo Ernesto Corredor-Alonso Claudia Haydee Sarai Caro-S ánchez Hugo Ricardo Dom ínguez-Malagón Source Type: research
Myxoinflammatory fibroblastic sarcoma: ultrastructural study of 7 cases
Ultrastruct Pathol. 2023 Dec 21:1-5. doi: 10.1080/01913123.2023.2292559. Online ahead of print.ABSTRACTSince first described, several studies about Myxoinflammatory fibroblastic sarcomas (MIFS) have been published stating the clinicopathological, morphological and immunohistochemical features. However, the ultrastructural findings of these MIFS are limited. Thus, the objective of the present paper is to describe the ultrastructural characteristics of these type of tumors by utilizing tissue that was embedded in paraffin and submitted for immunohistochemistry.The tissue of seven different cases was obtained for ultrastructu...
Source: Ultrastructural Pathology - December 21, 2023 Category: Pathology Authors: Guillermo Ernesto Corredor-Alonso Claudia Haydee Sarai Caro-S ánchez Hugo Ricardo Dom ínguez-Malagón Source Type: research
Microstructural changes in the irradiated and osteoradionecrotic bone: a SEM study
This study aims to investigate the radiotherapy-induced microstructural changes in the human mandible by scanning electron microscopy (SEM). Mandibular cortical bone biopsies were obtained from control, irradiated, and patients with osteoradionecrosis (ORN). Bone samples were prepared for light microscopy and SEM. The SEM images were analyzed for the number of osteons, number of Haversian canal (HC), diameter of osteon (D.O), the diameter of HC (D.HC), osteonal wall thickness (O.W.Th), number of osteocytes, and number of osteocytic dendrites. The number of osteons, D.O, D.HC, O.W.Th, the number of osteocytes, and osteocyti...
Source: Ultrastructural Pathology - December 20, 2023 Category: Pathology Authors: P Sridhar Reddy Kaapo Villikka Bina Kashyap Hannah Dekker Engelbert A J M Schulten Jopi J W Mikkonen Mikael Turunen Arto P Koistinen Nathalie Bravenboer Arja M Kullaa Source Type: research
Microstructural changes in the irradiated and osteoradionecrotic bone: a SEM study
This study aims to investigate the radiotherapy-induced microstructural changes in the human mandible by scanning electron microscopy (SEM). Mandibular cortical bone biopsies were obtained from control, irradiated, and patients with osteoradionecrosis (ORN). Bone samples were prepared for light microscopy and SEM. The SEM images were analyzed for the number of osteons, number of Haversian canal (HC), diameter of osteon (D.O), the diameter of HC (D.HC), osteonal wall thickness (O.W.Th), number of osteocytes, and number of osteocytic dendrites. The number of osteons, D.O, D.HC, O.W.Th, the number of osteocytes, and osteocyti...
Source: Ultrastructural Pathology - December 20, 2023 Category: Pathology Authors: P Sridhar Reddy Kaapo Villikka Bina Kashyap Hannah Dekker Engelbert A J M Schulten Jopi J W Mikkonen Mikael Turunen Arto P Koistinen Nathalie Bravenboer Arja M Kullaa Source Type: research
