Punctate IgG staining particles localize in the budding ballooning clusters of reactive foot processes in minimal change disease
Ultrastruct Pathol. 2023 Dec 14:1-7. doi: 10.1080/01913123.2023.2292590. Online ahead of print.ABSTRACTThe etiology of minimal change disease (MCD) remains a mystery as the only characteristic findings are the diffuse effacement of foot processes seen on electron microscopy (EM). Punctate IgG staining found floating outside glomerular capillary loops in MCD cases was recently identified as autoimmune antibodies against nephrin of podocytes. We hypothesized that the punctate IgG staining is located on budding ballooning clusters (BBC) of reactive foot processes in Bowman's space found on EM. We identified seven patients wit...
Source: Ultrastructural Pathology - December 15, 2023 Category: Pathology Authors: Ping L Zhang Vasudevan D Mahalingam Brandon D Metcalf Yazan A Al-Othman Wei Li Hassan D Kanaan Guillermo A Herrera Source Type: research
Punctate IgG staining particles localize in the budding ballooning clusters of reactive foot processes in minimal change disease
Ultrastruct Pathol. 2023 Dec 14:1-7. doi: 10.1080/01913123.2023.2292590. Online ahead of print.ABSTRACTThe etiology of minimal change disease (MCD) remains a mystery as the only characteristic findings are the diffuse effacement of foot processes seen on electron microscopy (EM). Punctate IgG staining found floating outside glomerular capillary loops in MCD cases was recently identified as autoimmune antibodies against nephrin of podocytes. We hypothesized that the punctate IgG staining is located on budding ballooning clusters (BBC) of reactive foot processes in Bowman's space found on EM. We identified seven patients wit...
Source: Ultrastructural Pathology - December 15, 2023 Category: Pathology Authors: Ping L Zhang Vasudevan D Mahalingam Brandon D Metcalf Yazan A Al-Othman Wei Li Hassan D Kanaan Guillermo A Herrera Source Type: research
Punctate IgG staining particles localize in the budding ballooning clusters of reactive foot processes in minimal change disease
Ultrastruct Pathol. 2023 Dec 14:1-7. doi: 10.1080/01913123.2023.2292590. Online ahead of print.ABSTRACTThe etiology of minimal change disease (MCD) remains a mystery as the only characteristic findings are the diffuse effacement of foot processes seen on electron microscopy (EM). Punctate IgG staining found floating outside glomerular capillary loops in MCD cases was recently identified as autoimmune antibodies against nephrin of podocytes. We hypothesized that the punctate IgG staining is located on budding ballooning clusters (BBC) of reactive foot processes in Bowman's space found on EM. We identified seven patients wit...
Source: Ultrastructural Pathology - December 15, 2023 Category: Pathology Authors: Ping L Zhang Vasudevan D Mahalingam Brandon D Metcalf Yazan A Al-Othman Wei Li Hassan D Kanaan Guillermo A Herrera Source Type: research
Punctate IgG staining particles localize in the budding ballooning clusters of reactive foot processes in minimal change disease
Ultrastruct Pathol. 2023 Dec 14:1-7. doi: 10.1080/01913123.2023.2292590. Online ahead of print.ABSTRACTThe etiology of minimal change disease (MCD) remains a mystery as the only characteristic findings are the diffuse effacement of foot processes seen on electron microscopy (EM). Punctate IgG staining found floating outside glomerular capillary loops in MCD cases was recently identified as autoimmune antibodies against nephrin of podocytes. We hypothesized that the punctate IgG staining is located on budding ballooning clusters (BBC) of reactive foot processes in Bowman's space found on EM. We identified seven patients wit...
Source: Ultrastructural Pathology - December 15, 2023 Category: Pathology Authors: Ping L Zhang Vasudevan D Mahalingam Brandon D Metcalf Yazan A Al-Othman Wei Li Hassan D Kanaan Guillermo A Herrera Source Type: research
Comparative effects of chemical and green zinc oxide nanoparticles in caprine testis: ultrastructural and steroidogenic enzyme analysis
Ultrastruct Pathol. 2023 Dec 12:1-14. doi: 10.1080/01913123.2023.2286963. Online ahead of print.ABSTRACTRecent advancements in nanotechnology has opened up enormous possibilities in diverse sectors such as industries, agriculture, environmental remediation, electronics, medicine and varied industries. Among metal oxide nanoparticles zinc oxide nanoparticles has gained considerable attention due to their fascinating physiochemical properties. Rapid growth in the use of zinc oxide nanoparticles (ZnONPs) in daily household products, food and feed additives, biological products, medicine, as antimicrobial agents, electronics a...
Source: Ultrastructural Pathology - December 12, 2023 Category: Pathology Authors: Sneha Bareja Rajnesh Kumar Sharma Source Type: research
Comparative effects of chemical and green zinc oxide nanoparticles in caprine testis: ultrastructural and steroidogenic enzyme analysis
Ultrastruct Pathol. 2023 Dec 12:1-14. doi: 10.1080/01913123.2023.2286963. Online ahead of print.ABSTRACTRecent advancements in nanotechnology has opened up enormous possibilities in diverse sectors such as industries, agriculture, environmental remediation, electronics, medicine and varied industries. Among metal oxide nanoparticles zinc oxide nanoparticles has gained considerable attention due to their fascinating physiochemical properties. Rapid growth in the use of zinc oxide nanoparticles (ZnONPs) in daily household products, food and feed additives, biological products, medicine, as antimicrobial agents, electronics a...
Source: Ultrastructural Pathology - December 12, 2023 Category: Pathology Authors: Sneha Bareja Rajnesh Kumar Sharma Source Type: research
Comparative effects of chemical and green zinc oxide nanoparticles in caprine testis: ultrastructural and steroidogenic enzyme analysis
Ultrastruct Pathol. 2023 Dec 12:1-14. doi: 10.1080/01913123.2023.2286963. Online ahead of print.ABSTRACTRecent advancements in nanotechnology has opened up enormous possibilities in diverse sectors such as industries, agriculture, environmental remediation, electronics, medicine and varied industries. Among metal oxide nanoparticles zinc oxide nanoparticles has gained considerable attention due to their fascinating physiochemical properties. Rapid growth in the use of zinc oxide nanoparticles (ZnONPs) in daily household products, food and feed additives, biological products, medicine, as antimicrobial agents, electronics a...
Source: Ultrastructural Pathology - December 12, 2023 Category: Pathology Authors: Sneha Bareja Rajnesh Kumar Sharma Source Type: research
The Protective effects of Vitamin E against alterations of rat testis structure induced by deltamethrin; histological, ultrastructure, and biochemical study
Ultrastruct Pathol. 2023 Dec 10:1-13. doi: 10.1080/01913123.2023.2292563. Online ahead of print.ABSTRACTDeltamethrin is a widely used synthetic pyrethroid pesticide. It causes reproductive toxicity. Aim of the work: it evaluates the impact of vitamin E in restoration of the testicular integrity of albino rats after toxicity induced by Deltamethrin. Thirty-six adult male albino rats were included, and they were further sub-divided into four experimental groups; Group A: six rats served as controls. Group B (Model): 10 rats equally divided into two sub-groups (B1): the rats received deltamethrin dissolved in oil in a dose of...
Source: Ultrastructural Pathology - December 11, 2023 Category: Pathology Authors: Ghada Nady Ouais Sherif A Kamar Ali Ahmed Mousa Mohamed Mostafa Sonbol Source Type: research
The Protective effects of Vitamin E against alterations of rat testis structure induced by deltamethrin; histological, ultrastructure, and biochemical study
Ultrastruct Pathol. 2023 Dec 10:1-13. doi: 10.1080/01913123.2023.2292563. Online ahead of print.ABSTRACTDeltamethrin is a widely used synthetic pyrethroid pesticide. It causes reproductive toxicity. Aim of the work: it evaluates the impact of vitamin E in restoration of the testicular integrity of albino rats after toxicity induced by Deltamethrin. Thirty-six adult male albino rats were included, and they were further sub-divided into four experimental groups; Group A: six rats served as controls. Group B (Model): 10 rats equally divided into two sub-groups (B1): the rats received deltamethrin dissolved in oil in a dose of...
Source: Ultrastructural Pathology - December 11, 2023 Category: Pathology Authors: Ghada Nady Ouais Sherif A Kamar Ali Ahmed Mousa Mohamed Mostafa Sonbol Source Type: research
Structural characterization and origin of surface vesicles in monocytes: another membranous pathway from cytoplasm to cell surface
Ultrastruct Pathol. 2023 Nov 30:1-10. doi: 10.1080/01913123.2023.2286972. Online ahead of print.ABSTRACTThe monocytes in acute monocytic leukemia (AML-M5b) were analyzed by scanning and transmission electron microscopy (SEM and TEM) to understand more fully their structure and origin. By SEM, monocytes exhibited localized expansions of the surface, some of which appeared to bud off as surface vesicles (SVs). Filopodial processes and pseudopodia were also present. TEM demonstrated that the SVs were composed of a double-membrane at the pole away from the cell body, and a single membrane nearer to the cell body. In the periph...
Source: Ultrastructural Pathology - December 1, 2023 Category: Pathology Authors: Yongxin Ru Shuxu Dong Jing Liu Jinhua Liu Brian Eyden Source Type: research
Structural characterization and origin of surface vesicles in monocytes: another membranous pathway from cytoplasm to cell surface
Ultrastruct Pathol. 2023 Nov 30:1-10. doi: 10.1080/01913123.2023.2286972. Online ahead of print.ABSTRACTThe monocytes in acute monocytic leukemia (AML-M5b) were analyzed by scanning and transmission electron microscopy (SEM and TEM) to understand more fully their structure and origin. By SEM, monocytes exhibited localized expansions of the surface, some of which appeared to bud off as surface vesicles (SVs). Filopodial processes and pseudopodia were also present. TEM demonstrated that the SVs were composed of a double-membrane at the pole away from the cell body, and a single membrane nearer to the cell body. In the periph...
Source: Ultrastructural Pathology - December 1, 2023 Category: Pathology Authors: Yongxin Ru Shuxu Dong Jing Liu Jinhua Liu Brian Eyden Source Type: research
Structural characterization and origin of surface vesicles in monocytes: another membranous pathway from cytoplasm to cell surface
Ultrastruct Pathol. 2023 Nov 30:1-10. doi: 10.1080/01913123.2023.2286972. Online ahead of print.ABSTRACTThe monocytes in acute monocytic leukemia (AML-M5b) were analyzed by scanning and transmission electron microscopy (SEM and TEM) to understand more fully their structure and origin. By SEM, monocytes exhibited localized expansions of the surface, some of which appeared to bud off as surface vesicles (SVs). Filopodial processes and pseudopodia were also present. TEM demonstrated that the SVs were composed of a double-membrane at the pole away from the cell body, and a single membrane nearer to the cell body. In the periph...
Source: Ultrastructural Pathology - December 1, 2023 Category: Pathology Authors: Yongxin Ru Shuxu Dong Jing Liu Jinhua Liu Brian Eyden Source Type: research
Structural characterization and origin of surface vesicles in monocytes: another membranous pathway from cytoplasm to cell surface
Ultrastruct Pathol. 2023 Nov 30:1-10. doi: 10.1080/01913123.2023.2286972. Online ahead of print.ABSTRACTThe monocytes in acute monocytic leukemia (AML-M5b) were analyzed by scanning and transmission electron microscopy (SEM and TEM) to understand more fully their structure and origin. By SEM, monocytes exhibited localized expansions of the surface, some of which appeared to bud off as surface vesicles (SVs). Filopodial processes and pseudopodia were also present. TEM demonstrated that the SVs were composed of a double-membrane at the pole away from the cell body, and a single membrane nearer to the cell body. In the periph...
Source: Ultrastructural Pathology - December 1, 2023 Category: Pathology Authors: Yongxin Ru Shuxu Dong Jing Liu Jinhua Liu Brian Eyden Source Type: research
Structural characterization and origin of surface vesicles in monocytes: another membranous pathway from cytoplasm to cell surface
Ultrastruct Pathol. 2023 Nov 30:1-10. doi: 10.1080/01913123.2023.2286972. Online ahead of print.ABSTRACTThe monocytes in acute monocytic leukemia (AML-M5b) were analyzed by scanning and transmission electron microscopy (SEM and TEM) to understand more fully their structure and origin. By SEM, monocytes exhibited localized expansions of the surface, some of which appeared to bud off as surface vesicles (SVs). Filopodial processes and pseudopodia were also present. TEM demonstrated that the SVs were composed of a double-membrane at the pole away from the cell body, and a single membrane nearer to the cell body. In the periph...
Source: Ultrastructural Pathology - December 1, 2023 Category: Pathology Authors: Yongxin Ru Shuxu Dong Jing Liu Jinhua Liu Brian Eyden Source Type: research
Structural characterization and origin of surface vesicles in monocytes: another membranous pathway from cytoplasm to cell surface
Ultrastruct Pathol. 2023 Nov 30:1-10. doi: 10.1080/01913123.2023.2286972. Online ahead of print.ABSTRACTThe monocytes in acute monocytic leukemia (AML-M5b) were analyzed by scanning and transmission electron microscopy (SEM and TEM) to understand more fully their structure and origin. By SEM, monocytes exhibited localized expansions of the surface, some of which appeared to bud off as surface vesicles (SVs). Filopodial processes and pseudopodia were also present. TEM demonstrated that the SVs were composed of a double-membrane at the pole away from the cell body, and a single membrane nearer to the cell body. In the periph...
Source: Ultrastructural Pathology - December 1, 2023 Category: Pathology Authors: Yongxin Ru Shuxu Dong Jing Liu Jinhua Liu Brian Eyden Source Type: research
