Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
Cilia impairment in bronchial epithelial cells detected in autopsy material of SARS-CoV-2-infected patient
Ultrastruct Pathol. 2023 Jun 12:1-6. doi: 10.1080/01913123.2023.2222167. Online ahead of print.ABSTRACTRecent studies indicate that cilia impairment, accompanied by the axonema loss and the basal body misorientation, is a common pathological feature of SARS-CoV-2-infected bronchial epithelial cells. However, these data were obtained using either cultured cells, or animal models, while in human postmortem material, cilia impairment has not been described yet. Here, we present direct observation of cilia impairment in SARS-CoV-2-infected bronchial epithelial cells using transmission electron microscopy of the autopsy materia...
Source: Ultrastructural Pathology - June 12, 2023 Category: Pathology Authors: Daria M Potashnikova Tatiana N Sotnikova Olesya M Shirokova Oleg V Zayratyants Elena Yu Vasilieva Eugene V Sheval Source Type: research
The effects of cisplatin and jaceosidin on SH-SY5Y neuroblastoma cells: an electron microscopic, molecular and biochemical study
In this study, our aim was to show both the single and combined effects of cisplatin and jaceosidin in SHSY-5Y neuroblastoma cells. For this purpose, we used MTT cellular viability assay, Enzyme-Linked Immunosorbent Assay (ELISA), Transmission Electron Microscopy (TEM), Immunofluorescence Staining Assay (IFA) and Western blotting (WB) assay. According to MTT findings, IC50 dose was detected as 50 µM cisplatin and 160 µM jaceosidin co-application. Therefore, experimental groups were finally selected as control, cisplatin, 160 µM jaceosidin and Cisplatin +160 µM jaceosidin. Cell viability was decreased in all groups, and...
Source: Ultrastructural Pathology - May 29, 2023 Category: Pathology Authors: Pinar Bayram Selina Aksak Karamese Bengul Özdemir Aysegul Durak Deniz Billur Source Type: research
The effects of cisplatin and jaceosidin on SH-SY5Y neuroblastoma cells: an electron microscopic, molecular and biochemical study
In this study, our aim was to show both the single and combined effects of cisplatin and jaceosidin in SHSY-5Y neuroblastoma cells. For this purpose, we used MTT cellular viability assay, Enzyme-Linked Immunosorbent Assay (ELISA), Transmission Electron Microscopy (TEM), Immunofluorescence Staining Assay (IFA) and Western blotting (WB) assay. According to MTT findings, IC50 dose was detected as 50 µM cisplatin and 160 µM jaceosidin co-application. Therefore, experimental groups were finally selected as control, cisplatin, 160 µM jaceosidin and Cisplatin +160 µM jaceosidin. Cell viability was decreased in all groups, and...
Source: Ultrastructural Pathology - May 29, 2023 Category: Pathology Authors: Pinar Bayram Selina Aksak Karamese Bengul Özdemir Aysegul Durak Deniz Billur Source Type: research
The effects of cisplatin and jaceosidin on SH-SY5Y neuroblastoma cells: an electron microscopic, molecular and biochemical study
In this study, our aim was to show both the single and combined effects of cisplatin and jaceosidin in SHSY-5Y neuroblastoma cells. For this purpose, we used MTT cellular viability assay, Enzyme-Linked Immunosorbent Assay (ELISA), Transmission Electron Microscopy (TEM), Immunofluorescence Staining Assay (IFA) and Western blotting (WB) assay. According to MTT findings, IC50 dose was detected as 50 µM cisplatin and 160 µM jaceosidin co-application. Therefore, experimental groups were finally selected as control, cisplatin, 160 µM jaceosidin and Cisplatin +160 µM jaceosidin. Cell viability was decreased in all groups, and...
Source: Ultrastructural Pathology - May 29, 2023 Category: Pathology Authors: Pinar Bayram Selina Aksak Karamese Bengul Özdemir Aysegul Durak Deniz Billur Source Type: research
