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Comparative Evaluation of Connective Tissue Graft with Pouch/Tunnel Technique versus Connective Tissue Graft with Coronally Advanced Tunnel Flap for the Treatment of Maxillary Recession Cases in Severe Periodontitis
Conclusion:Pouch/Tunnel technique along with connective tissue graft allows for the clinical coverage of gingival recessions that is equivalent to Coronally advanced flap with CTG, however this may improves the gingival thickness, KT and esthetic performance. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - September 4, 2021 Category: Biotechnology Source Type: research

Correction to: Biomimetic Biphasic Electrospun Scaffold for Anterior Cruciate Ligament Tissue Engineering
(Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - September 4, 2021 Category: Biotechnology Source Type: research

Stabilization of Lipid Lamellar Bilayer Structure of Stratum Corneum Modulated by Poly (2-methacryloyloxyethyl phosphorylcholine) in Relation to Skin Hydration and Skin Protection
CONCLUSION:The unique ion paired structure of PMPC enhances the barrier function of the SC by stabilizing LLB structure and hydration by inducing weakly bound water. The unique hydration state and stabilization effect from extended water exposure could provide a valuable information to prepare reliable artificial skin matrix and skin tissue. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - August 30, 2021 Category: Biotechnology Source Type: research

Role of Stromal Cell-Derived Factor-1 in Endothelial Progenitor Cell-Mediated Vascular Repair and Regeneration
AbstractEndothelial progenitor cells (EPCs) are immature endothelial cells that participate in vascular repair and postnatal neovascularization and provide a novel and promising therapy for the treatment of vascular disease. Studies in different animal models have shown that EPC mobilization through pharmacological agents and autologous EPC transplantation contribute to restoring blood supply and tissue regeneration after ischemic injury. However, these effects of the progenitor cells in clinical studies exhibit  mixed results. The therapeutic efficacy of EPCs is closely associated with the number of the progenitor cells ...
Source: Tissue Engineering and Regenerative Medicine - August 27, 2021 Category: Biotechnology Source Type: research

Extracorporeal Shock Wave Combined with Teriparatide-Loaded Hydrogel Injection Promotes Segmental Bone Defects Healing in Osteoporosis
CONCLUSION:In conclusion, ESW-combined with T-Gel injection could regulate the poor osteogenic microenvironment in osteoporotic defects and show potential for enhancing fragility fractures healing. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - August 24, 2021 Category: Biotechnology Source Type: research

Surface Creasing-Induced Micropatterned GelMA Using Heating-Hydration Fabrication for Effective Vascularization
ConclusionThe heating-hydration approach can successfully and easily produce the micropatterned gelMA that allows rapid and effective vascularization to potentially improve the functionalities of the tissue-engineered construct. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - August 13, 2021 Category: Biotechnology Source Type: research

Polydeoxyribonucleotide and Polynucleotide Improve Tendon Healing and Decrease Fatty Degeneration in a Rat Cuff Repair Model
CONCLUSION:PDRN and PN may improve tendon healing and decrease fatty degeneration after cuff repair. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - August 13, 2021 Category: Biotechnology Source Type: research

Effectiveness and Biocompatibility of Decellularized Nerve Graft Using an In Vivo Rat Sciatic Nerve Model
Conclusion:Based on inflammatory reaction, axonal regeneration, and functional outcomes, our newly developed decellularized nerve grafts were fairly biocompatible and had comparable effectiveness to autografts for nerve regeneration, which suggested it would be suitable for nerve reconstruction as an alternative to autograft. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - August 12, 2021 Category: Biotechnology Source Type: research

Three-Dimensional Modeling of the Structural Microenvironment in Post-Traumatic War Wounds
CONCLUSION:Altogether, these results suggest that the structural microenvironment present in traumatic war wounds has the potential to contribute to the development of post-traumatic HO. Our findings may support novel treatment strategies directed towards modifying the structural microenvironment after traumatic injury. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - August 7, 2021 Category: Biotechnology Source Type: research

Biomimetic Biphasic Electrospun Scaffold for Anterior Cruciate Ligament Tissue Engineering
Conclusion:Dual-phase electrospun scaffolds had mechanical properties and degradability similar to those of ACLs. They promoted differences in the morphology of MSCs and induced fibroblast differentiation under dynamic culture conditions. Animal experiments showed that ligamentous tissue regenerated well and supported joint stability. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - August 5, 2021 Category: Biotechnology Source Type: research

Effect of Human Umbilical Cord Matrix-Derived Mesenchymal Stem Cells on Bisphosphonate-Related Osteonecrosis of the Jaw
Conclusion:hUC-MSCs exerted therapeutic effects on BRONJin vitro andin vivo through their anti-cytotoxicity, anti-inflammatory activity and ability to recover bone regeneration. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - August 4, 2021 Category: Biotechnology Source Type: research

Effect of Leukocyte-Platelet Rich Fibrin (L-PRF) on Tissue Regeneration and Proliferation of Human Gingival Fibroblast Cells Cultured Using a Modified Method
Conclusion:The modified technique for the culture of HGFCs might be useful for the development of future experimental and clinical studies, besides L-PRF has great therapeutic potential in oral surgery fields. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - August 2, 2021 Category: Biotechnology Source Type: research

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Pass through the Filtration Barrier and Protect Podocytes in a 3D Glomerular Model under Continuous Perfusion
Conclusion:Using an innovative millifluidic model, able to mimic the human glomerular barrier, we were able to trace the EV passage and therapeutic effect in dynamic conditions. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - July 27, 2021 Category: Biotechnology Source Type: research

The Antioxidant Effect of Small Extracellular Vesicles Derived from Aloe vera Peels for Wound Healing
Conclusion:Overall results suggest that the A-EVs are promising as a potential agent for skin regeneration. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - July 27, 2021 Category: Biotechnology Source Type: research

Mucosal Vaccine Delivery Using Mucoadhesive Polymer Particulate Systems
AbstractVaccination has been recently attracted as one of the most successful medical treatments of the prevalence of many infectious diseases. Mucosal vaccination has been interested in many researchers because mucosal immune responses play part in the first line of defense against pathogens. However, mucosal vaccination should find out an efficient antigen delivery system because the antigen should be protected from degradation and clearance, it should be targeted to mucosal sites, and it should stimulate mucosal and systemic immunity. Accordingly, mucoadhesive polymeric particles among the polymeric particles have gaine...
Source: Tissue Engineering and Regenerative Medicine - July 25, 2021 Category: Biotechnology Source Type: research