Tissue Engineering and Regenerative Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The Progress of Stem Cell Therapy in Myocardial-Infarcted Heart Regeneration: Cell Sheet Technology
AbstractVarious tissues, including the heart, cornea, bone, esophagus, bladder and liver, have been vascularized using the cell sheet technique. It overcomes the limitations of existing techniques by allowing small layers of the cell sheet to generate capillaries on their own, and it can also be used to vascularize tissue-engineered transplants. Cell sheets eliminate the need for traditional tissue engineering procedures such as isolated cell injections and scaffold-based technologies, which have limited applicability. While cell sheet engineering can eliminate many of the drawbacks, there are still a few challenges that n...
Source: Tissue Engineering and Regenerative Medicine - July 20, 2022 Category: Biotechnology Source Type: research

Adenosine-Prefabricated Adipose Tissue Improves Fat Graft Survival by Promoting VEGF-Dependent Angiogenesis
CONCLUSION:Adenosine prefabrication in fat improved the graft survival by enhancing angiogenesis through the VEGF/VEGFR axis in the preadipocytes and endothelial cells. Therefore, this method may be used as a novel strategy to increase the retention rate in fat grafts. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - July 19, 2022 Category: Biotechnology Source Type: research

Progress of Polysaccharide-Contained Polyurethanes for Biomedical Applications
AbstractPolyurethane (PU) has been widely examined and used for biomedical applications, such as catheters, blood oxygenators, stents, cardiac valves, drug delivery carriers, dialysis devices, wound dressings, adhesives, pacemaker, tissue engineering, and coatings for breast implants due to its mechanical flexibility, high tear strength, biocompatibility, and tailorable foams although bio-acceptability, biodegradability and controlled drug delivery to achieve the desired properties should be considered. Especially, during the last decade, the development of bio-based PUs has raised public awareness because of the concern w...
Source: Tissue Engineering and Regenerative Medicine - July 11, 2022 Category: Biotechnology Source Type: research

A Biodegradable Polymeric Matrix for the Repair of Annulus Fibrosus Defects in Intervertebral Discs
Conclusion:PGA-HA scaffolds used for AF closure support repair tissue formation in an ovine lumbar disc defect model. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - July 11, 2022 Category: Biotechnology Source Type: research

Stem Cell-Derived Exosomes: A New Method for Reversing Skin Aging
AbstractSenescence is an inevitable natural life process that involves structural and functional degeneration of tissues and organs. Recently, the process of skin aging has attracted much attention. Determining a means to delay or even reverse skin aging has become a research hotspot in medical cosmetology and anti-aging. Dysfunction in the epidermis and fibroblasts and changes in the composition and content of the extracellular matrix are common pathophysiological manifestations of skin aging. Reactive oxygen species and matrix metalloproteinases play essential roles in this process. Stem cells are pluripotent cells that ...
Source: Tissue Engineering and Regenerative Medicine - July 9, 2022 Category: Biotechnology Source Type: research

Development and Application of Three-Dimensional Bioprinting Scaffold in the Repair of Spinal Cord Injury
AbstractSpinal cord injury (SCI) is a disabling and destructive central nervous system injury that has not yet been successfully treated at this stage. Three-dimensional (3D) bioprinting has become a promising method to produce more biologically complex microstructures, which fabricate living neural constructs with anatomically accurate complex geometries and spatial distributions of neural stem cells, and this is critical in the treatment of SCI. With the development of 3D printing technology and the deepening of research, neural tissue engineering research using different printing methods, bio-inks, and cells to repair S...
Source: Tissue Engineering and Regenerative Medicine - June 29, 2022 Category: Biotechnology Source Type: research

Expandable Lung Epithelium Differentiated from Human Embryonic Stem Cells
ConclusionExpandable lung epithelium thus offer a stable, convenient, easily scalable and high-yielding cell source for applications in biomedicine. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - June 7, 2022 Category: Biotechnology Source Type: research

An Insight of Nanomaterials in Tissue Engineering from Fabrication to Applications
Tissue engineering is a research domain that deals with the growth of various kinds of tissues with the help of synthetic composites. With the culmination of nanotechnology and bioengineering, tissue engineering has emerged as an exciting domain. Recent literature describes its various applications in biomedical and biological sciences, such as facilitating the growth of tissue and organs, gene delivery, biosensor-based detection, etc. It deals with the development of biomimetics to repair, restore, maintain and amplify or strengthen several biological functions at the level of tissue and organs. Herein, the synthesis of n...
Source: Tissue Engineering and Regenerative Medicine - June 4, 2022 Category: Biotechnology Source Type: research

Lytic Bacteriophage as a Biomaterial to Prevent Biofilm Formation and Promote Neural Growth
ConclusionThe purified lytic phages were proven to be a highly bioactive nanomaterial. The phage-chitosan composite material not only promoted neural cell proliferation but also effectively prevent bacterial growth, a major cause of implant failure and removal.Graphical abstract (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - June 1, 2022 Category: Biotechnology Source Type: research

Cocktail Formula and Application Prospects for Oral and Maxillofacial Organoids
AbstractOral and maxillofacial organoids (OMOs), tiny tissues and organs derived from stem cells cultured through 3-d cell culture models, can fully summarize the cell tissue structure, physiological functions and biological characteristics of the source tissues in the body. OMOs are applied in areas such as disease modelling, developmental and regenerative medicine, drug screening, personalized treatment, etc. Although the construction of organoids in various parts of the oral and maxillofacial (OM) region has achieved considerable success, the existing cocktail formulae (construction strategies) are not widely applicable...
Source: Tissue Engineering and Regenerative Medicine - May 25, 2022 Category: Biotechnology Source Type: research

Preparation and Biocompatibility Study of Contrast-Enhanced Hernia Mesh Material
CONCLUSION:These results highlight the excellent biocompatibility of the contrast-enhanced material, which is suitable for human abdominal wall tissue engineering. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - May 25, 2022 Category: Biotechnology Source Type: research

Enhanced Bone Regeneration by Bone Morphogenetic Protein-2 after Pretreatment with Low-Intensity Pulsed Ultrasound in Distraction Osteogenesis
Conclusion:The results of this study suggest that the combined treatment of BMP-2 and LIPUS can lead to enhanced bone healing in DO and that effective bone healing can be achieved through the application of LIPUS before BMP-2. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - May 20, 2022 Category: Biotechnology Source Type: research

Correction: Demineralized Dentin Matrix for Dental and Alveolar Bone Tissues Regeneration: An Innovative Scope Review
(Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - May 20, 2022 Category: Biotechnology Source Type: research

Decellularized Human Adipose Tissue as an Alternative Graft Material for Bone Regeneration
CONCLUSION:The DM developed in this study is expected to address the problem of insufficient supply of graft materials and contribute to the treatment of bone defects of critical size as an alternative bone graft material with preserved extracellular matrix components. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - May 12, 2022 Category: Biotechnology Source Type: research

Re-Cellularised Kidney Scaffold for Chikungunya Virus Propagation: A Novel Approach
Conclusion:This method will be a breakthrough for future virus culture, drug interaction and to study its effect on extracellular matrix alterations. This study will also allow us to investigate the correct role of any vaccine or antiviral drugs and their effects on re-engineered organ matrices before moving towards the animal models.Graphical abstract (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - May 9, 2022 Category: Biotechnology Source Type: research