Vasculitis Presenting as Autonomic Failure
Conclusions:
This is a unique GPA case presenting with autonomic failure and pituitary dysfunction with conclusive objective findings of autonomic dysfunction. Autonomic dysfunction and other disease manifestations were responsive to immunosuppressive therapy. (Source: The Neurologist)
Source: The Neurologist - July 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Meta-Analysis of Perioperative Stroke and Mortality in CABG Patients With Carotid Stenosis
No abstract available (Source: The Neurologist)
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Letter to the Editor Source Type: research
Does the Initiation of Fluoxetine Postacute Stroke Result in Improved Functional Recovery?: A Critically Appraised Topic
Conclusion:
Among patients with stroke, early initiation of fluoxetine did not result in improved functional recovery. Lower rates of depression were observed in the fluoxetine-treated group; however these patients experienced higher rates of bone fracture. (Source: The Neurologist)
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Critically Appraised Topics Source Type: research
COVID-19–Associated Ischemic Stroke in a Patient on Therapeutic Anticoagulation
Conclusion:
Ischemic stroke in anticoagulated patients with COVID-19 has been previously reported. Such cases emphasize the severity of the coronavirus virus associated hypercoagulable state. A majority of reported cases have occurred in patients continuing their ambulatory therapy. Overall, such cases are likely underreported. There are current trials comparing therapeutic versus prophylactic dose anticoagulation in patients with COVID-19. There are no studies specifically addressing anticoagulation agent failure in these patients. Further research is required this area to determine the optimal therapy for patients wi...
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Aβ-related Angiitis (ABRA)—A Rare Paraneoplastic Cause of Cerebral Vasculitis in a Young Patient: A Pathway From Unspecific Neurological Symptoms to Final Diagnosis
Conclusions:
The reported case demonstrates our diagnostic approach and the clinical difficulties in validating a rare cause of encephalopathy in a young patient with nonspecific clinical and neuroradiological findings. Because of the possibility of an effective treatment, it is important to consider ABRA in the differential diagnosis especially when blood tests, analysis of cerebrospinal fluid, and angiography show normal results. Since a paraneoplastic genesis is presumed, a search for an underlying tumor disease should be considered. (Source: The Neurologist)
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Giant Cell Arteritis: When an Inspection Is Essential
Conclusion:
When dealing a patient with a typical headache, a prominent artery in the inspection, and a visualization of halo sign in ultrasound examination, this diagnosis must be considered. (Source: The Neurologist)
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Erythropoietin-Associated Posterior Reversible Encephalopathy Syndrome
Conclusion:
Recombinant human erythropoietin (RhEPO) may be an underrecognized cause of PRES and should be considered in patients receiving this treatment regardless of the absence or presence of renal impairment. RhEPO-mediated precipitation/exacerbation of hypertension, alterations in cerebral blood flow, and changes in endothelial integrity may underlie this association. MRI signal changes are reversible and typical for that of PRES, and significant improvement of symptoms can be expected. (Source: The Neurologist)
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Nonabducent Cranial Neuropathies in Cerebral Venous Sinus Thrombosis: A Case Report and Literature Review
Conclusion:
A systematic review identified 26 patients from 21 articles with nonabducent cranial neuropathies. Seven patients had lower motor neuron facial palsy, 13 patients had hearing loss or vertigo with vestibulocochlear involvement, and 6 patients had other mixed cranial nerve palsies with CVST. They are usually associated with transverse sinus and/or sigmoid sinus thrombosis. They have a good prognosis with improvement and complete resolution of cranial neuropathies in most cases usually in 1 month. (Source: The Neurologist)
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Concurrent Stroke and Myocardial Infarction After Mild COVID-19 Infection
Conclusions:
Our experience with these cases suggests that patients with mild symptoms can also present thromboembolic complications once the acute phase of COVID-19 infection has passed. (Source: The Neurologist)
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Froin Syndrome, a Rare Complication of Multiple Myeloma
Conclusion:
Leptomeningeal myelomatosis associated with MM can cause blockage of CSF circulation leading to Froin syndrome. Inflammatory or neoplastic conditions should be considered as an underlying etiology. (Source: The Neurologist)
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Hyperammonemia in Patients With Status Epilepticus Treated With or Without Valproic Acid
Background:
Hyperammonemia is a common side effect of valproic acid (VPA) and can occur after generalized seizures, but the clinical significance is unclear. The aim of this study was to better understand the clinical practice and utility of ammonia testing in status epilepticus (SE) treated with or without VPA.
Methods:
Charts of adult patients with SE from St. Mary’s Hospital Intensive Care Units (ICUs) (Mayo Clinic, Rochester, MN) from 2011 to 2016 were reviewed. Clinical factors were compared between patients who had ammonia checked versus those who did not, and those with normal ammonia versus hyperammone...
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Original Articles Source Type: research
Clinical Diagnosis of Central Vertigo in Patients With Dizziness in Emergency Practice
Conclusions:
To avoid missing central dizziness in a patient, diagnostic abilities should be improved by including careful interviews and confirmation of the presence/absence of accompanying symptoms. Furthermore, collaboration with neurology and neurosurgery departments is important for improving the diagnosis in suspected cases. (Source: The Neurologist)
Source: The Neurologist - May 1, 2021 Category: Neurology Tags: Original Articles Source Type: research
Stroke Patients Without COVID-19 Symptoms: Is There a Need to Screen?
Conclusion:
Our patient’s case clearly supports the screening for COVID-19 in stroke patients who are without COVID-19 symptoms, appreciating the significant value it adds to infection control, clinical management, and outcomes amidst this global pandemic. (Source: The Neurologist)
Source: The Neurologist - March 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Creutzfeldt-Jakob Disease May Present Early With Unusual Bulbar Predominance
Conclusions:
CJD may present with progressive bulbar symptoms similar to acute inflammatory demyelinating polyradiculoneuropathy (MF variant), motor neuron disease, or autoimmune brainstem encephalitis. It becomes even higher on the differentials especially with no response to immunotherapy. (Source: The Neurologist)
Source: The Neurologist - March 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
Isolated Medial Longitudinal Fasciculus Midbrain Infarction Mimicking Medial Rectus Paralysis
Conclusion:
Isolated midbrain-medial longitudinal fasciculus infarction without contralateral abducting nystagmus is a rare occurrence. It can be differentiated from partial oculomotor palsy by assessing the convergence reflex, primary gaze, and diffusion-tensor imaging. (Source: The Neurologist)
Source: The Neurologist - March 1, 2021 Category: Neurology Tags: Case Report/Case Series Source Type: research
