Papilledema and Peripheral Neuropathies
Conclusions:
Based on a personal case report and from an extensive review of the medical literature, we identify 2 distinct patterns. First, radiculoneuropathy may be a consequence of intracranial pressure (peripheral nerve involvement corresponding to a “false localizing sign”). Second, papilledema may occur after the onset of inflammatory neuropathy. For such cases, the pathophysiological mechanism remains unknown (eg, reactional inflammatory processes or actions of unknown autoantibodies) and requires further elucidation. (Source: The Neurologist)
Source: The Neurologist - November 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Successful Thrombolysis in the Setting of Marfan Syndrome and Chronic Aortic Dissection
Conclusion:
To our knowledge, this is the first case of Marfan syndrome with chronic aortic dissection undergoing thrombolysis for acute ischemic stroke with a near-complete recovery of neurological deficit and favorable long-term outcome. (Source: The Neurologist)
Source: The Neurologist - November 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Tenecteplase Averting Mechanical Thrombectomy in Emergent Large Vessel Occlusion
Conclusion:
This case exemplifies the potential of tenecteplase in achieving swift reperfusion in patients with large vessel occlusion associated with a substantial mismatch penumbral pattern. (Source: The Neurologist)
Source: The Neurologist - November 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Intraosseous Administration of Hypertonic Saline in Acute Brain-Injured Patients: A Prospective Case Series and Literature Review
Conclusions:
In this prospective case series, IO administration of 3% HTS was feasible, well-tolerated on the basis of nonverbal indicators of pain in the majority of patients and resulted in an appropriate rise in serum sodium levels. IO fills a niche among vascular access options for HTS, in emergent neurological situations when central venous access is not readily available or peripheral intravenous access is difficult to obtain. (Source: The Neurologist)
Source: The Neurologist - November 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Relationship Between Sleep Characteristics and Sudden Unexplained Death Risk in Epilepsy
Conclusion:
Our results emphasized a remarkable magnitude of the comorbidity of sleep disorders in patients with epilepsy, even for those who do not have complaints about sleep. As SUDEP cases are frequently seen during sleep, it is important to evaluate sleep in patients with epilepsy. (Source: The Neurologist)
Source: The Neurologist - November 1, 2019 Category: Neurology Tags: Original Articles Source Type: research
Bronzino’s Claw Hand
Conclusion:
There is in fact no portrayal of a unilateral ulnar pathology. If it were, then it means that many of Bronzino’s subjects suffered from exactly the same condition. (Source: The Neurologist)
Source: The Neurologist - November 1, 2019 Category: Neurology Tags: Original Articles Source Type: research
A Cross-Sectional Analysis of Migraine-Related Disability in CADASIL: A Mayo Clinic Cohort
Conclusions:
A bimodal distribution of migraine-related disability was observed. A third of individuals had a severe disability and appeared medically refractory to medical migraine prophylactic measures. This study may serve as a reference point for future trials quantitatively gauging response of novel migraine treatment strategies within this unique population. (Source: The Neurologist)
Source: The Neurologist - November 1, 2019 Category: Neurology Tags: Original Articles Source Type: research
Cause or Consequence: The Relationship Between Cerebral Venous Thrombosis and Idiopathic Intracranial Hypertension
Conclusion:
CSVT is a common clinical entity among the causes of IIHT, and it should be taken into consideration in this patient group. However, there is a need for a common guideline for laboratory and imaging methods to understand the etiopathogenesis of childhood IIHT and determine the patients at risk. (Source: The Neurologist)
Source: The Neurologist - September 1, 2019 Category: Neurology Tags: Original Article Source Type: research
Glial Fibrillary Acidic Protein (GFAP) Autoimmunity in the Setting of Seropositive Rheumatoid Arthritis Treated With Etanercept
Conclusion:
This case expands on the previously reported cases of GFAP immunoglobulin G autoimmunity by describing an associated inflammatory large fiber peripheral neuropathy. (Source: The Neurologist)
Source: The Neurologist - September 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Dupuytren, Ledderhose, and Peyronie Diseases After Primidone Use For Essential Tremor
Conclusions:
There are a few reports associating barbiturate use to connective tissue disorders, and some suggest that drug withdrawal may result in a better prognosis. Therefore, physicians must be aware of such adverse events when caring for patients on long-term barbiturate use. (Source: The Neurologist)
Source: The Neurologist - September 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Intravenous Thrombolysis For Acute Ischemic Stroke in Fabry Disease
Conclusion:
The present case supports the scarce data underscoring the safety of intravenous thrombolysis for acute ischemic stroke in Fabry disease patients even when cerebral microbleeds are present. (Source: The Neurologist)
Source: The Neurologist - September 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Safety of Early Repeated Thrombolysis: A Case Report
Conclusion:
This case report suggests that further randomized studies may evaluate whether repeated IVtPA may be safe and effective in ERS occurring shortly after a previous stroke when patients experience a period of complete neurological regression, minor disability, and a small infarct volume. Should the hypothesis be confirmed, small volume core and wide volume penumbra at perfusion CT may support the decision of adopting IVtPA repetition. (Source: The Neurologist)
Source: The Neurologist - September 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Recurrent Stroke in Giant Cell Arteritis Despite Immunotherapy
Conclusions:
This case highlights several important features of strokes in GCA: the predilection for the dural entry point of cerebral blood vessels, the progression of disease despite steroids, and the need to quickly escalate treatment in these cases. As seen in our patient, however, this disease carries high morbidity and mortality and patients often have poor outcomes despite aggressive immunosuppression. (Source: The Neurologist)
Source: The Neurologist - June 28, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Fatal Intracerebral Hemorrhage in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL): A Case Report
The main clinical manifestations of Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) are migraine with aura, ischemic strokes, and progressive cognitive decline. Intracerebral hemorrhage (ICH) has been described in CADASIL, but is not widely recognized. Here we report a case with CADASIL that presented with fatal ICH. A 57-year-old right-handed man of Pakistani descent with history of genetically confirmed CADASIL, hypertension, and mood disorder presented to the emergency department via Emergency Medical Services (EMSs) after he was found down. Initial neurological exami...
Source: The Neurologist - June 28, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Dural Arteriovenous Fistula With Sinus Thrombosis and Venous Reflux Presenting as Parkinsonism: A Case Report
We present a case of a 57-year-old man with a left transverse sinus DAVF along with sigmoid thrombosis, cortical venous reflux, and congestion, that initially presented as parkinsonism. The patient was alert and fully oriented; however, decreased facial expressions were noted. His left forearm showed rigidity and bradykinesia, and it was difficult for the patient to smoothly perform rapid alternating movement testing. His complaints about hearing a rhythmic bruit above the left ear, particularly when lying down, alerted the physician of the presence of vascular lesions. Magnetic resonance imaging and angiography confirmed ...
Source: The Neurologist - June 28, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
