West Nile Neuroinvasive Disease Presenting as Elsberg Syndrome
Conclusions:
West Nile virus neuroinvasive disease is an uncommon condition that should be considered in patients with ES. Determining the etiology of ES in the acute setting may avoid unnecessary diagnostic investigations and treatments. (Source: The Neurologist)
Source: The Neurologist - September 1, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
Neurology Residents as Comprehensive Educators (Neuro RACE)
Residents are expected to be educators often without any formal schooling, and many continue a career in academic medicine where they play a pivotal role in education. However, few resident curricula have been published to include instruction in teaching, particularly in the field of Neurology. To guide Neurology residents as they take on their role as a clinician-educator, we developed a 1-year curriculum (Neurology Residents as Comprehensive Educators “Neuro RACE”) with monthly sessions divided into didactics, small group discussions, and interactive kinetic learning. A postcurriculum survey was used to evaluate the ...
Source: The Neurologist - September 1, 2018 Category: Neurology Tags: Original Article Source Type: research
Therapy With Mesenchymal Stem Cells in Parkinson Disease: History and Perspectives
Conclusions:
The results of MSC therapy in animal models and some clinical trials suggest that such cellular therapy may slow the progression of PD and promote neuroregeneration. However, further research is needed to address the limitations of an eventual clinical application. (Source: The Neurologist)
Source: The Neurologist - June 28, 2018 Category: Neurology Tags: Review Article Source Type: research
A Fatal Case of Undiagnosed Candida Meningitis: Role of Computer-assisted Diagnosis
Diagnostic error is an increasing health care concern. An intravenous drug abuser with chronic meningitis died after a prolonged hospitalization from fungal meningitis diagnosed at autopsy. We examine the diagnostic pitfalls and consider how a computer-assisted diagnostic system may influence the outcome of an otherwise fatal condition. (Source: The Neurologist)
Source: The Neurologist - June 28, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
Acute Right Middle Cerebral Artery Occlusion Resulting in Acute Systolic Heart Failure, Cerebral T-Waves, and QTc Prolongation: A Case Report
Conclusions:
Acute ischemic infarcts, particularly to the right insular cortex, can result in ECG abnormalities, such as QT prolongation and T-wave inversion, as well as acute systolic heart failure; all of which may be reversible after the acute phase of the stroke. (Source: The Neurologist)
Source: The Neurologist - June 28, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
Myelitis and Polyradiculoneuropathy With Severe Pain: Unusual Neurological Manifestations as Presenting Symptoms of Brucellosis
We report 2 patients with systemic brucellosis presenting with neurological symptoms: A 28-year-old female with progressive hemiparesis associated with severe refractory thoracic and lumbar pain, whose spinal magnetic resonance imaging identified longitudinally extensive myelitis. Brucella agglutination test was positive in blood; however, cerebrospinal fluid cytochemical, serological testing, and cultures were negative. A 58-year-old male with intermittent fever in the evening, associated with severe refractory cervical and lumbar spinal and radicular pain. Blood workup identified leukocytosis, elevated inflammatory marke...
Source: The Neurologist - June 28, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
A Case Report of Overlapping Miller Fisher Syndrome, Guillain-Barré Syndrome, and the Bickerstaff Brainstem Encephalitis
Conclusions:
As the clinical course of MFS-GBS-BBE overlapping syndrome is variable, involving not only the peripheral but also the central nervous system, the establishment of a comprehensive therapeutic strategy is warranted. (Source: The Neurologist)
Source: The Neurologist - June 28, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
Nonaneurysmal Subarachnoid Hemorrhage in Sickle Cell Disease: Description of a Case and a Review of the Literature
We describe the case of an 18-year-old female affected by HbSS genotype SCD presenting with reversible cerebral vasoconstriction syndrome (RCVS) as well as features of posterior reversible encephalopathy syndrome and convexity subarachnoid hemorrhage (SAH) after transfusion of red blood cells. We reviewed the existing literature dealing with SCD, blood transfusion, and hemorrhagic strokes. To our knowledge, this case presentation is unique with convexity SAH predominantly attributable to a RCVS spectrum disorder occurring in the setting of a recent blood transfusion in an adolescent female with SCD. As this case illustrate...
Source: The Neurologist - June 28, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
Inter-rater Agreement for the Diagnosis of Stroke Versus Stroke Mimic
Conclusions:
We found modest agreement among surveyed physicians in distinguishing ischemic stroke syndromes from stroke mimics in patients without radiographic evidence of infarction and clinical improvement after thrombolysis. Methods to improve diagnostic consensus after thrombolysis are needed to assure acute ischemic stroke patients and stroke mimics are treated safely and accurately. (Source: The Neurologist)
Source: The Neurologist - June 28, 2018 Category: Neurology Tags: Original Articles Source Type: research
Evaluation of Epicardial Fat Thickness in Young Patients With Embolic Stroke of Undetermined Source
This study investigated the echocardiographic epicardial adipose tissue measurement in young patients with embolic stroke of undetermined source (ESUS).
Materials and Methods:
We studied 77 volunteers, including 40 patients with ESUS (mean age 43±8 y, 16 female patients) and 37 healthy subjects (mean age 38±7 y, 20 female subjects). All necessary biochemical parameters were analyzed, and epicardial fat thickness (EFT) was measured by echocardiography in all subjects. Additional related diagnostic work-up was conducted in each patient, according to the patients’ clinical presentation.
Results:
The patients wit...
Source: The Neurologist - June 28, 2018 Category: Neurology Tags: Original Articles Source Type: research
Is Adjunctive Progesterone Effective in Reducing Seizure Frequency in Patients With Intractable Catamenial Epilepsy? A Critically Appraised Topic
Conclusions:
Cyclic natural progesterone is not superior to placebo in reducing seizure frequency in women with intractable partial epilepsy. Posthoc findings suggest that progesterone may benefit a subset of women with perimenstrually exacerbated seizures. (Source: The Neurologist)
Source: The Neurologist - May 1, 2018 Category: Neurology Tags: Critically Appraised Topics Source Type: research
Spot Sign in Acute Intracerebral Hemorrhage in Magnetic Resonance Imaging: A Case Report and Review of the Literature
We present a case of MRI spot sign and review of the literature.
Case Report:
We present a patient on oral coumadin for history of deep venous thrombosis and pulmonary embolus who presented with a right basal ganglia hemorrhage. She had a computed tomography angiography showing contrast extravasation and also had a hyperacute MRI showing similar contrast extravasation. Follow-up imaging showed hematoma enlargement.
Discussion:
We present here a case of corroboration of the computed tomography angiography spot sign with the MRI spot sign. The prognostic value of the MRI spot sign is unclear. Future studies should eval...
Source: The Neurologist - May 1, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
Vertebral Artery Occlusion Causing Facial Colliculus and Opalski Stroke Syndromes Simultaneously
Brainstem stroke syndromes refer to a group of vascular disorders that occur secondary to occlusion of small perforating arteries of the posterior circulation. Although such syndromes result in a characteristic clinical picture, they are challenging to localize. In practice, such syndromes are rarely seen in their pure form, and the clinical consequences of a given vascular lesion are probably less predictable than for arteries in the anterior circulation. If 2 or more brainstem strokes happen simultaneously, localization becomes much harder. In this article, we present a case with 2 embolic strokes that occurred simultane...
Source: The Neurologist - May 1, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
The Mayo Clinic Experience With the Neurological Complications of the CTLA-4 Inhibitor Ipilimumab
We describe our institution’s experience with ipilimumab and illustrate 2 cases of presumed autoimmune neurological phenomenon resulting from its use. (Source: The Neurologist)
Source: The Neurologist - May 1, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
Ongoing Photosensitivity in An Elderly Patient With Jeavons Sydrome
Conclusion:
Our elderly patient with Jeavons syndrome with ongoing remarkable photosensitivity demonstrated that it may continue to older ages, although it is uncommon. (Source: The Neurologist)
Source: The Neurologist - May 1, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research
