Heart Rate Variability Analysis: A Useful Tool to Assess Poststroke Cardiac Dysautonomia
Background:
Neurogenic heart syndrome represents a phenomenon often encountered in clinical practice after ischemic stroke. Further poststroke cardiovascular complications are possibly related to cardiac autonomic dysregulation. Multiple Trigonometric Regressive Spectral (MTRS) analysis of the heart rate variability (HRV) allows a precise evaluation of cardiovascular modulation under different conditions.
Objectives:
This research aims to evaluate the impact of the middle cerebral artery (MCA) ischemic stroke on cardiac autonomic function, using the MTRS analysis of HRV, during sympathetic and parasympathetic activati...
Source: The Neurologist - May 1, 2020 Category: Neurology Tags: Original Articles Source Type: research
Stroke-Associated Pneumonia: A Retrospective Study of Risk Factors and Outcomes
Introduction:
Pneumonia is the most common complication after stroke, but our knowledge on risk factors and predictors of stroke-associated pneumonia (SAP) is limited. We sought to evaluate the predictors and outcomes of SAP among acute ischemic stroke (AIS) hospitalizations.
Methods:
This is a cross-sectional study of the Nationwide Inpatient Sample database from the year 2003 to 2014. We identified adult hospitalizations with AIS using International Classification of Diseases, ninth revision, clinical modification (ICD-9-CM) codes. The SAP was identified by the presence of a secondary diagnosis of hospital-acquired ...
Source: The Neurologist - May 1, 2020 Category: Neurology Tags: Original Articles Source Type: research
Is King-Devick Testing, Compared With Other Sideline Screening Tests, Superior for the Assessment of Sports-related Concussion?: A Critically Appraised Topic
Conclusion:
K-D testing has high sensitivity and specificity for detecting sideline concussion. Compared with other sideline screening tools that do not include vision testing, it has greater accuracy. Screening for concussion is optimized when multiple testing modalities are used in conjunction. (Source: The Neurologist)
Source: The Neurologist - March 1, 2020 Category: Neurology Tags: Critically Appraised Topics Source Type: research
Nonatrial Fibrillation was Associated With Early Neurological Improvement After Intravenous Thrombolysis With rt-PA in Patients With Acute Ischemic Stroke
Background:
Intravenous thrombolysis is the only approved pharmacological treatment for acute ischemic stroke (AIS) patients, but the immediate response to thrombolysis varies by patient.
Objective:
To investigate the factors associated with early neurological improvement (ENI) after the administration of intravenous recombinant tissue plasminogen activator (rt-PA) treatment to AIS patients within 4.5 hours of onset.
Methods:
Demographics, onset to treatment time, risk factors, and clinical and laboratory data of 209 AIS patients undergoing intravenous rt-PA therapy at a Chinese hospital between January 2013 and Au...
Source: The Neurologist - March 1, 2020 Category: Neurology Tags: Original Article Source Type: research
Thrombolysis for Acute Ischemic Stroke Following Transcatheter Aortic Valve Replacement: Case Report and Literature Review
Conclusion:
Previously undescribed, we suggest that tPA should be considered for post-TAVR AIS patients who otherwise satisfy inclusion and exclusion criteria. (Source: The Neurologist)
Source: The Neurologist - March 1, 2020 Category: Neurology Tags: Case Report/Case Series Source Type: research
Treating Paroxysmal Sympathetic Hyperactivity With Enteral Baclofen in Anoxic Brain Injury
Conclusion:
This case series reviews the current therapies used for PSH and discusses 2 patients with uncontrolled PSH secondary to anoxic brain injury. Both patients arose from coma and had significant symptomatic improvement with enteral baclofen treatment. Thus, enteral baclofen should be considered as a primary treatment for PSH to prevent sustained symptoms and prolonged hospitalizations. (Source: The Neurologist)
Source: The Neurologist - March 1, 2020 Category: Neurology Tags: Case Report/Case Series Source Type: research
Feasibility of a Nonmydriatic Ocular Fundus Camera in an Outpatient Neurology Clinic
Conclusions:
Using nonmydriatic fundus photography in an outpatient neurology clinic is feasible without disrupting patient flow or causing patient discomfort. Findings of optic nerve pallor, optic nerve swelling, or normal optic nerves were particularly relevant to these patients seen for headaches or demyelinating disease and helped inform immediate diagnosis and management. (Source: The Neurologist)
Source: The Neurologist - March 1, 2020 Category: Neurology Tags: Original Article Source Type: research
Relationship Between Sleep Characteristics and Sudden Unexplained Death Risk in Epilepsy: Erratum
No abstract available (Source: The Neurologist)
Source: The Neurologist - December 31, 2019 Category: Neurology Tags: Erratum Source Type: research
MRI Punctate Sign and CTA Spot Sign for Primary Intracerebral Hemorrhage
No abstract available (Source: The Neurologist)
Source: The Neurologist - December 31, 2019 Category: Neurology Tags: Letter to the Editor Source Type: research
A Probable Case of Recurrent Bickerstaff Brainstem Encephalitis With Fulminant Course in a Pediatric Patient
Conclusion:
Although Bickerstaff brainstem encephalitis tends to involve the brainstem, outcomes of brain death have been rarely reported, even more so in the pediatric age group. This case report sheds light on, possibly, the first reported fatality of Bickerstaff encephalitis among children. (Source: The Neurologist)
Source: The Neurologist - December 31, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Clinical Usefulness of Cell-Free DNA as a Prognostic Marker in Acute Ischemic Stroke
Objective:
Stroke has become the second most common cause of death. Several biomarkers have been detected in the peripheral blood from stroke patients, but none has found a place in clinical practice. Cell-free DNA (cf-DNA) liberated into the blood soon after the onset of stroke might be useful for assessing disease severity and prognosis.
Study Design and Methods:
A total of 54 patients presenting with ischemic stroke were recruited consecutively with the exclusion of patients having trauma, tumor, infections, and organ failure. The cf-DNA was extracted by circulating nucleic acid kit from Qiagen and measured by real...
Source: The Neurologist - December 31, 2019 Category: Neurology Tags: Original Article Source Type: research
Low Heteroplasmy Rates Argue Against the m.3243A>G Variant as the Cause of Auditory Agnosia
No abstract available (Source: The Neurologist)
Source: The Neurologist - December 31, 2019 Category: Neurology Tags: Letter to the Editor Source Type: research
Protean Manifestations and Diagnostic Challenges Including Discordance Between Electrodiagnostic-Radiologic Studies in Neurolymphomatosis
Conclusion:
This clinical phenotype reinforces previously reported presentations of neurolymphomatosis and the ability of multimodal diagnostics, when combined with clinical suspicion phenotype, to enable diagnosis of malignant lymphocytic infiltration of the CNS and PNS. (Source: The Neurologist)
Source: The Neurologist - December 31, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Myasthenia Gravis Crisis and Atrial Fibrillation
Conclusion:
New-onset AF can occur during MG crisis. The cardiac outcome improves with treatment of the underlying disease, after initial cardiac stabilization. (Source: The Neurologist)
Source: The Neurologist - December 31, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
Leukoencephalopathy With Predominant Infratentorial Involvement Caused by a Novel ABCD1 Mutation: Does the Spinocerebellar Variant of Adrenoleukodystrophy Exist?
Conclusions:
X-ALD should be included in the differential diagnosis of adult leukoencephalopathies with predominant involvement of infratentorial structures, that is, the cerebellum and brainstem. From a classification perspective, our patient (of white origin), like others (all of Asian origin), should be considered as suffering from a variant of adrenomyeloneuropathy rather than from spinocerebellar X-ALD. Actually, the term “spinocerebellar” or similar ones, such as “cerebello-brainstem dominant form,” should be limited to those exceptional cases, in which both the clinical and neuroimaging findings point excl...
Source: The Neurologist - November 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research
