Systolic Blood Pressure and Mortality in Community-Dwelling Older Adults: The Role of Frailty
ConclusionOur results suggest the presence of effect modification by frailty indicating a possible negative effect for elevated SBP in non-frail older adults and a U-shaped relationship of SBP in frail older adults with respect to mortality even after adjusting for diastolic blood pressure. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - October 10, 2022 Category: Nutrition Source Type: research

Poor Appetite & amp; Aging: The Role of Physical Activity under a Geroscience Perspective
(Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - October 8, 2022 Category: Nutrition Source Type: research

Intrinsic Capacity Impairment Patterns and their Associations with Unfavorable Medication Utilization: A Nationwide Population-Based Study of 37,993 Community-Dwelling Older Adults
ConclusionsWe identified five distinct impairment patterns of IC, and each impairment pattern, particularly the “depression with cognitive impairment” and “impairment in all domains”, was associated with higher odds of EPP and PIMs. Further longitudinal and intervention studies are needed to explore long-term outcomes of different impairment pattern and their reversibility. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - October 3, 2022 Category: Nutrition Source Type: research

Emerging Evidence on the Use of Probiotics and Prebiotics to Improve the Gut Microbiota of Older Adults with Frailty Syndrome: A Narrative Review
ConclusionProbiotics and prebiotics may potentially prevent frailty syndrome or improve the quality of life of patients with this disorder. However, there is not enough information about their appropriate doses and periods of administration. Therefore, further investigations are required to determine these factors and improve their efficacy as therapeutic approaches for frailty syndrome. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - September 17, 2022 Category: Nutrition Source Type: research

Prevalence and Associates of Frailty Status in Different Stages of Chronic Kidney Disease: A Cross-Sectional Study
ConclusionPrefrailty and frailty are quite common among HD and CKD stage 3 –4 patients. Being an HD patient is an independent risk factor for non-robust (frail or prefrail) status. Our findings point out a remarkably high prevalence of frailty severity (prefrailty/frailty) phenotype among patients with advanced CKD stages. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - September 17, 2022 Category: Nutrition Source Type: research

Association between Preexisting Sarcopenia and Stroke in Patients with Type 2 Diabetes Mellitus
ConclusionPreexisting sarcopenia increased the risk of stroke in patients with type 2 diabetes mellitus. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - September 14, 2022 Category: Nutrition Source Type: research

Clinical Efficacy of Multidomain Interventions among Multimorbid Older People Stratified by the Status of Physio-Cognitive Declines: A Secondary Analysis from the Randomized Controlled Trial for Healthy Aging
ConclusionsThe integrated multidomain lifestyle intervention plus multimorbidity management significantly improved cognitive function, and enhanced quality of life among older adults with multimorbidity and PCDS in the communities. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - September 14, 2022 Category: Nutrition Source Type: research

Association of Homocysteine and Risks of Long-Term Cardiovascular Events and All-Cause Death among Older Patients with Obstructive Sleep Apnea: A Prospective Study
ConclusionstHcy, a marker of prognosis for older OSA patients, was significantly associated with the increased risk of MACE and all-cause death in this population independent of BMI, smoking status, and other potential risk factors, but not all clinical components events of MACE. New therapeutic approaches for older patients with OSA should mitigate tHcy-associated risks of MACE, and even all-cause death. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - September 14, 2022 Category: Nutrition Source Type: research

Functional Decline in COVID-19 Older Survivors Compared to Other Pneumonia Patients, a Case Control Study
ConclusionCOVID-19 does not seem to be responsible for a more frequent or severe functional decline than other infectious pneumonia in older and comorbid population after 3 month follow up. In this population, pneumonia is associated with functional decline in almost 1 in 2 cases. The individual preadmission frailty seems to be a more important predictor of functional decline, encouraging multidimensional care management for this population. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - September 14, 2022 Category: Nutrition Source Type: research

SARC-F and SARC-CalF Scores as Mortality Risk Factors in Older Men with Cancer: A Longitudinal Study from Peru
ConclusionsThe risk of sarcopenia evaluated by SARC-F and SARC-CalF scores was associated with an increased risk of mortality in older men with cancer. Both scales proved to be useful and accessible instruments for the identification of groups at risk of mortality. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - September 14, 2022 Category: Nutrition Source Type: research

Validation of F3ALLS Assessment in Older Adults
ConclusionThe F3ALLS questionnaire adequately classifies person at risk versus not at risk for falls, and higher (worse) F3ALLS scores are associated with falls over 6 months. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - September 14, 2022 Category: Nutrition Source Type: research

Iron Deficiency and Incident Infections among Community-Dwelling Adults Age 70 Years and Older: Results from the DO-HEALTH Study
ConclusionBased on this prospective study among generally healthy European community-dwelling older adults, iron deficiency was not associated with the incidence rate of overall infections but may increase the incidence of severe infections. Intervention studies are needed to prove the causality of this observation. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - August 27, 2022 Category: Nutrition Source Type: research

Calf Circumference and All-Cause Mortality: A Systematic Review and Meta-Analysis Based on Trend Estimation Approaches
ConclusionsCalf circumference is a valid anthropometric measure for mortality risk prediction in a community, nursing home, or hospital. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - August 27, 2022 Category: Nutrition Source Type: research

Determinants of Resting Energy Expenditure in Very Old Nursing Home Residents
ConclusionREE of very old nursing home residents is influenced by FFM, calorie intake, functional abilities, and CRP levels and is poorly predicted by classical equations based on age, gender, height, and weight. This suggests a metabolic adaptation to caloric restriction and inflammation and prompts to consider the level of physical activity and muscle loss when assessing caloric requirements in this population. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - August 27, 2022 Category: Nutrition Source Type: research

Association between the Lymphocyte-to-C-Reactive Protein Ratio and Survival Outcomes in Cancer Patients with GLIM-Defined Malnutrition: A Multicenter Study
ConclusionsAssessing the LCR can help the medical staff identify cancer patients with nutritional deficiency at high risk of oncological outcomes and develop individualized therapeutic strategies. (Source: The Journal of Nutrition, Health and Aging)
Source: The Journal of Nutrition, Health and Aging - August 23, 2022 Category: Nutrition Source Type: research