Surgical Oncology Clinics of North America This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Current Controversies in Neoadjuvant Therapy for Pancreatic Cancer
Over the last two decades, there have been significant changes in the management of patients with localized pancreatic cancer. The rationale for an evolution toward a neoadjuvant approach and summary of relevant clinical trials is reviewed. Controversies in identifying optimal neoadjuvant therapeutic approaches are discussed. (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Authors: Erin P. Ward, Herbert J. Zeh III, Susan Tsai Source Type: research

Pancreaticoduodenectomy and Vascular Reconstruction
Pancreaticoduodenectomy with vascular resection/reconstruction can be safely completed following 6 standard steps plus basic principles of vascular surgery. Particular attention is paid to the location of the tumor relative to the 2 first-order vein branches, portal vein —splenic vein –superior mesenteric vein confluence, inferior mesenteric vein, and the presence of arterial perineural invasion. Successful resection following neoadjuvant therapy can result in median survival 3 times that of historical controls. (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Authors: Kathleen K. Christians, Douglas B. Evans Source Type: research

Health Care Disparities and the Future of Pancreatic Cancer Care
There have been tremendous advances in the diagnosis and treatment of pancreatic cancer in the past decade, yet we are failing to achieve equitable outcomes for all patient populations. Disparities exist in the incidence, diagnosis, treatment, and outcomes of patients with pancreatic cancer. Inequities are based on racial and ethnic group, sex, socioeconomic status, and geography. To address disparities, future steps must focus on research methods, including collection and methodology, and policy measures, including access, patient tools, hospital incentives, and workforce diversity. Through these comprehensive efforts, we...
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Authors: Marianna V. Papageorge, Douglas B. Evans, Jennifer F. Tseng Source Type: research

Updates on the Management of Pancreatic Cancer
Management of pancreatic cancer has evolved rapidly over the past decade. The use of multimodality therapy has produced superior patient outcomes and has fueled the acceptance of neoadjuvant therapy as the standard approach to operable pancreatic cancer at most high-volume centers. The complexities of delivering neoadjuvant therapy requires the commitment of a multidisciplinary team. The focus of this issue is to highlight the importance of a multidisciplinary approach, and to that end, the issue is organized to provide a comprehensive overview of the management of pancreatic cancer from diagnosis to staging and treatment....
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Authors: Susan Tsai, Douglas B. Evans Tags: Preface Source Type: research

Pancreatic Cancer
This issue of the Surgical Oncology Clinics of North America focuses on the management of pancreatic cancer. Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide with over 430,000 related deaths annually.1 Unlike some other cancers, the incidence of pancreatic cancer continues to increase with relatively little improvement in survival. Despite some advances over the last several decades, pancreatic cancer has been characterized by tumor cell resistance to chemotherapy agents, which has resulted in the failure of many traditional cancer treatments. (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Authors: Timothy M. Pawlik Tags: Foreword Source Type: research

Current Management of Pancreatic Cancer
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Authors: Susan Tsai, Douglas B. Evans Source Type: research

Copyright
ELSEVIER (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Source Type: research

Contributors
TIMOTHY M. PAWLIK, MD, MPH, MTS, PhD, FACS, FRACS (Hon.) (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Source Type: research

Contents
Timothy M. Pawlik (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Source Type: research

Forthcoming Issues
Disparities and Determinants of Health in Surgical Oncology (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - September 10, 2021 Category: Surgery Source Type: research

Pathology and Molecular Characteristics of Pancreatic Cancer
This article focuses on the molecular and pathology alterations in PDAC. (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - July 22, 2021 Category: Surgery Authors: Joseph F. Kearney, Volkan Adsay, Jen Jen Yeh Source Type: research

Evolution of Systemic Therapy in Metastatic Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma is characterized by early systemic dissemination, a complex tumor microenvironment, as well as significant intratumoral and intertumoral heterogeneity. Treatment options and survival in pancreatic ductal adenocarcinoma have improved steadily over the last 3  decades. Although cytotoxic chemotherapy is currently the mainstay of treatment for pancreatic ductal adenocarcinoma, evolving therapeutic strategies are aimed at targeting the tumor microenvironment, metabolism, and the tumor–host immune balance. (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - July 22, 2021 Category: Surgery Authors: Mandana Kamgar, Sakti Chakrabarti, Aditya Shreenivas, Ben George Source Type: research

Multimodality Imaging for the Staging of Pancreatic Cancer
This article reviews key principles of the acquisition, interpretation, and reporting of pancreatic ductal adenocarcinoma imaging with computed tomography scanning and highlights potential roles for newer and supplemental imaging technologies. We discuss the importance of structured interpretation and reporting for providing the most complete and accurate assessment of tumor stage and resectability. (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - July 22, 2021 Category: Surgery Authors: Martin McKinney, Michael O. Griffin, Parag P. Tolat Source Type: research

Therapeutic Targeting of Autophagy in Pancreatic Cancer
This article provides a brief review of the therapeutic opportunity of inhibiting autophagy in pancreatic cancer. The autophagic process, importance of autophagy in pancreatic cancer, relevant clinical trials, and new agents in preclinical and clinical development are discussed. (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - July 21, 2021 Category: Surgery Authors: Mona Foth, Ignacio Garrido-Laguna, Conan G. Kinsey Source Type: research

Inherited Pancreatic Cancer Syndromes and High-Risk Screening
Pancreatic cancer is the third leading cause of cancer death in the United States, with a 5-year survival rate of 9%. Individuals with inherited pancreatic cancer syndromes are at an increased risk for developing pancreatic cancer and may benefit from pancreatic cancer surveillance with the goal to detect and intervene on early-stage cancer or high-risk precursor lesions. Given the screening implications for family members and therapeutic implications for probands, all patients diagnosed with pancreatic cancer are recommended to undergo germline genetic testing. (Source: Surgical Oncology Clinics of North America)
Source: Surgical Oncology Clinics of North America - July 21, 2021 Category: Surgery Authors: Leah H. Biller, Brian M. Wolpin, Michael Goggins Source Type: research