The Long-Term Psychiatric and Cardiovascular Morbidity and Mortality of Restless Legs Syndrome and Periodic Limb Movements of Sleep
This article summarizes the literature investigating the potential consequences of both RLS and PLMS. (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - April 15, 2021 Category: Sleep Medicine Authors: Benjamin Wipper, John W. Winkelman Source Type: research
Sleep-Related Rhythmic Movement Disorder
Sleep-related rhythmic movements disorder (SRRMD), typically considered a benign pediatric sleep disorder, comprise a group of movement disorders that occur predominantly early in childhood with an average age of onset of 9 months of age. Although it usually resolves spontaneously as the child ages, it can persist into adulthood. In this article, the authors review the identification, diagnosis, and management of SRRMD in children and adults. (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - April 15, 2021 Category: Sleep Medicine Authors: Lourdes M. DelRosso, Irene Cano-Pumarega, Samantha Anguizola Source Type: research
Fragmentary Hypnic Myoclonus and Other Isolated Motor Phenomena of Sleep
Excessive fragmentary hypnic myoclonus, hypnic jerks, hypnagogic foot tremor, alternating leg muscle activation, and sleep-related cramps are less known sleep-related motor disorders (SRMDs). These manifestations are frequently missed or misinterpreted polygraphic findings that can be frequently confused with the more frequent SRMDs. These symptoms can present as isolated motor symptoms but can be also the cause of otherwise cryptogenic insomnias and somnolence. Expanding the knowledge on these isolated symptoms and defining their polygraphic and clinical features are essential for their identification. However, clear cut-...
Source: Sleep Medicine Clinics - April 15, 2021 Category: Sleep Medicine Authors: Luca Baldelli, Federica Provini Source Type: research
Propriospinal Myoclonus
Propriospinal myoclonus (PSM) consists of paroxysmal and sudden jerks involving axial flexion trunk and hip muscles, conditioning sudden myoclonias of the trunk and arms/limbs, both spontaneous and triggered by sensory stimulations, emerging in relaxed wakefulness typically during the transition between wake and sleep. Generally, PSM originates from a thoracic myelomere and spreads caudally and rostrally, provoking flexion and/or extension movements, leading to jumps or trunk jerks. They appear triggered by the lying-down position and disappear when the subject stands up. The main consequences are the difficulties in sleep...
Source: Sleep Medicine Clinics - April 15, 2021 Category: Sleep Medicine Authors: Marco Zucconi, Francesca Casoni, Andrea Galbiati Source Type: research
Sleep Disorders in Parkinson Disease
Sleep disorders in Parkinson disease have attracted the attention of clinicians and researchers for decades. Recently, major advances in their clinical characterization, polysomnographic description, pathophysiologic understanding, and treatment took place. Parkinson disease encompasses the whole spectrum of sleep medicine: every category of sleep disorder can be observed in these patients. Video polysomnography frequently is indicated, sometimes followed by multiple sleep latency/maintenance of wakefulness tests. Additional studies may include actigraphy, cardiorespiratory polygraphy, and dim light melatonin assessment. T...
Source: Sleep Medicine Clinics - April 15, 2021 Category: Sleep Medicine Authors: Ambra Stefani, Birgit H ögl Source Type: research
The Isolated Form of Rapid Eye Movement Sleep Behavior Disorder
The diagnosis of rapid eye movement (REM) sleep behavior disorder (SBD) requires videopolysomnography detection of excessive electromyographic activity during REM sleep, which is time consuming and difficult. An easier, faster, reliable, and reproducible methodology is needed for its diagnosis. The isolated form of RBD represents an early manifestation of the synucleinopathies Parkinson disease and dementia with Lewy bodies. There is a need to find neuroprotective drugs capable of preventing parkinsonism and dementia onset in isolated RBD. Clonazepam and melatonin ameliorate the RBD symptoms, but therapeutic alternatives a...
Source: Sleep Medicine Clinics - April 15, 2021 Category: Sleep Medicine Authors: Alex Iranzo, Lina Agudelo Ramos, Sabela Novo Source Type: research
Pediatric Restless Legs Syndrome
Early-onset restless legs syndrome has a relatively high prevalence in pediatrics, is highly familial, and is often preceded by a diagnosis of periodic limb movement disorder or childhood insomnia. Diagnostic criteria are derived but not equal to those of the adult syndrome and are adapted according to children ’s age and linguistic competence. Diagnosis requires parents or caregivers to participate; video-polysomnographic nocturnal recording, although not mandatory, may help confirm dubious cases. The syndrome severely impacts children’s sleep and cognitive-behavioral abilities. Iron supplementation i s currently the ...
Source: Sleep Medicine Clinics - April 9, 2021 Category: Sleep Medicine Authors: Rosalia Silvestri, Lourdes DelRosso Source Type: research
Akathisia and Restless Legs Syndrome
This article proposes that it involves an increased presynaptic dopaminergic transmission in the ventral striatum and concomitant strong activation of postsynaptic dopamine D1 receptors, which form complexes (heteromers) with dopamine D3 and adenosine A1 receptors. It also proposes that in DRBA-induced akathisia, increased dopamine release depends on inactivation of autoreceptors, whereas in RLS it depends on a brain iron deficiency –induced down-regulation of striatal presynaptic A1 receptors. (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - April 9, 2021 Category: Sleep Medicine Authors: Sergi Ferr é, Xavier Guitart, César Quiroz, William Rea, Celia García-Malo, Diego García-Borreguero, Richard P. Allen, Christopher J. Earley Source Type: research
Piecing Together the Puzzle of Adherence in Sleep Medicine
SLEEP MEDICINE CLINICS (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - January 21, 2021 Category: Sleep Medicine Authors: Jessie P. Bakker Source Type: research
Copyright
ELSEVIER (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - January 21, 2021 Category: Sleep Medicine Source Type: research
Forthcoming Issues
Movement Disorders in Sleep (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - January 21, 2021 Category: Sleep Medicine Source Type: research
Contributors
JESSIE P. BAKKER, MS, PhD (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - January 21, 2021 Category: Sleep Medicine Source Type: research
Contents
Jessie P. Bakker (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - January 21, 2021 Category: Sleep Medicine Source Type: research
Piecing Together the Puzzle of Adherence in Sleep Medicine
This issue of Sleep Medicine Clinics focuses primarily on our current understanding and future directions regarding adherence to therapy for sleep disorders, as described by experts in the field. The title, “Piecing Together the Puzzle of Adherence,” nods to how much we have learned to date while acknowledging that adherence remains a complex and puzzling behavioral phenomenon. (Source: Sleep Medicine Clinics)
Source: Sleep Medicine Clinics - January 12, 2021 Category: Sleep Medicine Authors: Jessie P. Bakker Tags: Preface Source Type: research
Adherence to Cognitive Behavior Therapy for Insomnia
This article discusses information extracted from 53 studies that have measured adherence to cognitive behavior therapy for insomnia. There has been an increase in more complex and less biased methods for assessing adherence that move beyond simply asking the patients whether they have adhered to the intervention or not. There is a need for a consensus around how to measure adherence, if clinicians want to arrive at an estimate of optimal adherence. Heterogeneity of studies, particularly in the way adherence is operationalized, prohibited conclusions about the relationship between adherence and outcome, as well as about pr...
Source: Sleep Medicine Clinics - December 27, 2020 Category: Sleep Medicine Authors: Sommer Agnew, Annie Valli ères, Ailie Hamilton, Stephanie McCrory, Marek Nikolic, Simon D. Kyle, Leanne Fleming, Megan R. Crawford Source Type: research
