Rheumatic Disease Clinics of North America This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Pediatric Rheumatic Disease in Lower to Middle-Income Countries
Pediatric rheumatology subspecialists treat chronic autoimmune diseases with onset in childhood. Prompt diagnosis and ongoing management of these conditions are imperative to prevent damage from ongoing inflammation. Here, we aim to describe the current landscape of pediatric rheumatic disease in lower to middle-income countries (LMICs) and explore current barriers to understanding global disease burden. We then examine innovative strategies to promote a more equitable future for children and young people living with rheumatic diseases worldwide. (Source: Rheumatic Disease Clinics of North America)
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Christiaan Scott, Sujata Sawhney, Laura B. Lewandowski Source Type: research

The Role of Pediatric Rheumatologists in Autoimmune Brain Disease
The spectrum of autoimmune and inflammatory brain diseases continues to evolve with medical advances facilitating both the detection of inflammation of the central nervous system and the discovery of novel disease mechanisms. The clinical overlap of these disorders with primary rheumatic diseases and the efficacy of immunotherapy have led to strong partnerships between pediatric rheumatologists, neurologists, psychiatrists, and other providers in the care of children with these conditions. Early diagnosis and initiation of targeted therapy improve clinical outcomes, highlighting the importance of interdisciplinary collabor...
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Kathryn Taylor, Eyal Muscal, Heather Van Mater Source Type: research

Biomarkers in Childhood-Onset Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a complex, multisystem chronic autoimmune disease. Because of its diverse phenotypes, diagnosis of SLE can be challenging, and current biomarkers are insufficient. Childhood-onset SLE (cSLE), although less prevalent, has higher morbidity and mortality, and early diagnosis is critical for improving outcomes. Many studies have focused on discovering new biomarkers to better diagnose and monitor SLE and cSLE. Herein, the authors aim to review the most investigated biomarkers in development for cSLE, focusing on those that can be measured in the blood or urine. (Source: Rheumatic Disease C...
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Ellen M. Cody, Hermine I. Brunner Source Type: research

Technology to Assess and Treat Pain in Pediatric Rheumatology
Advancements in eHealth offer unique opportunities for assisting in and augmenting aspects of evidence-based pain evaluation and management with children and adolescents. In this article, we present an overview of some of the opportunities and challenges in pain eHealth for pediatric rheumatologists to consider while caring for children and adolescents seen in their practice. (Source: Rheumatic Disease Clinics of North America)
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Mark Connelly, Rebecca Rachael Lee Source Type: research

The Promises and Perils of Social Media for Pediatric Rheumatology
This article reviews the promises and perils of social media related to health, focusing on its potential use to support research and care of children with PRD. (Source: Rheumatic Disease Clinics of North America)
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Jonathan S. Hausmann, Elissa R. Weitzman Source Type: research

Role of Environment in Pediatric Rheumatic Diseases
Studying environmental risk factors for pediatric rheumatic diseases (PRD) is important because the identification of these factors may lead to strategies to prevent disease, and to new insights into pathogenesis and therapeutic targets. Compared with other chronic diseases, there are few environmental epidemiology studies in PRD. Although strong risk factors common to all PRDs have not been identified, some exposures including infection, smoke exposure, and ultraviolet radiation have been associated with several of them. High-technology studies, especially of microbiomics and metabolomics, are increasing and will likely l...
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Colleen K. Correll Source Type: research

Assessing Patient-Reported Outcomes in Pediatric Rheumatic Diseases
For children with pediatric rheumatic diseases (PRDs), the inclusion of patient-reported outcomes (PROs) is critical to inform decision making in health care delivery and research settings. PROs are direct reports from a child on their health status, without interpretation by anyone else. PROs improve understanding of the patient experience, allow clinicians to provide patient-centered care, and add value to clinical trials. When PROs cannot be collected directly from the patient, caregiver-proxy reports can provide important information on the child ’s more observable symptoms and functioning. In this article, we descri...
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Christina K. Zigler, Rachel L. Randell, Bryce B. Reeve Source Type: research

Ultrasonography in Pediatric Rheumatology
This review highlights the increasing evidence from the last few years supporting the use of musculoskeletal ultrasonography (MSUS) in the evaluation and management of patients with pediatric rheumatic diseases, particularly focusing on juvenile idiopathic arthritis. Recently developed definitions for the sonographic appearance of healthy and pathologic joints in children are discussed. Further topics explored include how MSUS enhances the diagnosis of inflammatory joint disease (synovitis, enthesitis, tenosynovitis), including the detection of subclinical synovitis. There is a brief summary on the use of ultrasonography i...
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Patricia Vega-Fernandez, Tracy V. Ting, Laura Pratt, Christine M. Bacha, Edward J. Oberle Source Type: research

Precision Medicine
Despite an increase in the number of available therapeutics, many children with rheumatic disease continue to experience active inflammatory disease and treatment failure. One reason for treatment failure is the lack of dosing paradigms to account for the wide between-patient variability in drug pharmacokinetics because of developmental changes or genetic polymorphisms that effect drug absorption, distribution, metabolism, and elimination. This review highlights several strategies to optimize dosing for biologic and nonbiologic disease-modifying antirheumatic drugs, including therapeutic drug monitoring, pharmacogenomics, ...
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Stephen J. Balevic, Anna Carmela P. Sagcal-Gironella Source Type: research

Transitioning to Adulthood with a Rheumatic Disease
Both pediatric and adult rheumatology care teams play a central role in health care transition, the shift from child- and family-centered to adult-oriented health care. Components of transition preparation include readiness assessment, setting self-management goals, and spending time in clinical visits without a parent present. Pediatric providers and families should work together to create a transfer plan, identifying a new adult rheumatology care provider, providing a medical summary before transfer, and anticipating changes in health insurance. For high-risk transfers, direct communication between providers is recommend...
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Rebecca E. Sadun, Lauren T. Covert, Erica F. Lawson Source Type: research

Mental Health in Pediatric Rheumatology
Mental health problems are more common in children with pediatric rheumatologic diseases (PRDs) than healthy peers. Mental health problems affect disease-related outcomes and health-related quality of life (HRQOL), so addressing these problems can improve clinical and psychosocial outcomes. Mental health screening tools are available, and there are resources available to aid in integrating mental health care into the clinical setting. By implementing these tools, mental health problems can be recognized and addressed. (Source: Rheumatic Disease Clinics of North America)
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Erin Brennan Treemarcki, Ashley N. Danguecan, Natoshia R. Cunningham, Andrea M. Knight Source Type: research

Patient Engagement in Pediatric Rheumatology Research
Patient engagement in pediatric rheumatology research can ensure protocol acceptability, project relevance, facilitate a successful study, and share results with the community. Research partners can collaborate along the entire continuum of research, contributing both lived and professional experience with roles as small as a single point-in-time consultation to as large as multi-year shared leadership. Patient and caregiver partners can be found in the myriad of places-the clinic, in advocacy organizations, on social media, and through networking with existing patient partners. Patient engagement begins with relationship ...
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Vincent Del Gaizo, Melanie Kohlheim Source Type: research

Disparities in Pediatric Rheumatic Diseases
Health and health care disparities in pediatric rheumatology are prevalent among socially disadvantaged and marginalized populations based on race/ethnicity, socioeconomic position, and geographic region. These groups are more likely to experience greater disease severity, morbidity, mortality, decreased quality of life, and poor mental health outcomes, which are in part due to persistent structural and institutional barriers, including decreased access to quality health care. Most of the research on health and health care disparities in pediatric rheumatology focuses on juvenile idiopathic arthritis and childhood-onset sy...
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Alisha M. Akinsete, Jennifer M.P. Woo, Tamar B. Rubinstein Source Type: research

Early Sexual Health and Reproductive Implications in Pediatric Rheumatic Diseases
A comprehensive review of reproductive health subtopics, including puberty, menarche, sexual orientation, gender identity, and gynecologic cancers as they pertain to patients with pediatric rheumatic diseases and those who care for them. Rheumatic disease medications and their effect on reproductive health across childhood and adolescence are also reviewed. (Source: Rheumatic Disease Clinics of North America)
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Cuoghi Edens Source Type: research

The Impact of Pediatric Rheumatic Diseases on Sexual Health, Family Planning, and Pregnancy
A comprehensive review of reproductive health subtopics, including sexual intercourse, romantic relationships, contraception, sexually transmitted infections, pregnancy, and infertility, as they pertain to patients with pediatric rheumatic diseases and those who care for them. (Source: Rheumatic Disease Clinics of North America)
Source: Rheumatic Disease Clinics of North America - November 17, 2021 Category: Rheumatology Authors: Cuoghi Edens Source Type: research