Health-promoting benefits of lentils: Anti-inflammatory and anti-microbial effects
Curr Res Physiol. 2024 Mar 5;7:100124. doi: 10.1016/j.crphys.2024.100124. eCollection 2024.ABSTRACTThis paper describes how lentils (Lens culinaris species) can positively affect health by reducing inflammation, providing antioxidants, and displaying antimicrobial properties. Lentils are rich in proteins, essential amino acids, minerals, and fibers, making them a valuable source of nutrition, particularly in low and middle-income countries. Lentils have many health benefits, including positive effects on diabetes management, support for cardiovascular health, and antioxidative properties. The antioxidative properties of le...
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Rachel Alexander Abdullah Khaja Nicholas Debiec Alex Fazioli Mary Torrance Mohammed S Razzaque Source Type: research

Investigating the role of CFTR in human and mouse myometrium
CONCLUSION: These results demonstrate decreased myometrial function when CFTR is inhibited, which may have implications on pregnancy and labour outcome and therapeutic decisions for labour in CF patients.PMID:38501132 | PMC:PMC10945125 | DOI:10.1016/j.crphys.2024.100122 (Source: Physiological Research)
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Clodagh Prendergast Susan Wray Daniella Dungate Christine Martin Andra Vaida Elizabeth Brook Cecilia Ani Chioma Helen Wallace Source Type: research

Breathing patterns and associated cardiovascular changes in intermittently breathing animals: (Partially) correcting a semantic quagmire
Exp Physiol. 2024 Mar 19. doi: 10.1113/EP091784. Online ahead of print.ABSTRACTMany animal species do not breathe in a continuous, rhythmic fashion, but rather display a variety of breathing patterns characterized by prolonged periods between breaths (inter-breath intervals), during which the heart continues to beat. Examples of intermittent breathing abound across the animal kingdom, from crustaceans to cetaceans. With respect to human physiology, intermittent breathing-also termed 'periodic' or 'episodic' breathing-is associated with a variety of pathologies. Cardiovascular phenomena associated with intermittent breathin...
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Warren Burggren Andreas Fahlman William Milsom Source Type: research

Arabidopsis BECLIN1-induced autophagy mediates reprogramming in tapetal programmed cell death by altering the gross cellular homeostasis
This study demonstrates that BECN1-mediated autophagy is inhibitory to the dPCD of the tapetum, but the severity of autophagy leads to autophagic death in the later stages. The delayed and altered mode of tapetal degeneration resulted in male sterility.PMID:38503186 | DOI:10.1016/j.plaphy.2024.108471 (Source: Physiological Research)
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Surendra Pratap Singh Rishi Kumar Verma Ridhi Goel Verandra Kumar Ram Rakshpal Singh Samir V Sawant Source Type: research

Health-promoting benefits of lentils: Anti-inflammatory and anti-microbial effects
Curr Res Physiol. 2024 Mar 5;7:100124. doi: 10.1016/j.crphys.2024.100124. eCollection 2024.ABSTRACTThis paper describes how lentils (Lens culinaris species) can positively affect health by reducing inflammation, providing antioxidants, and displaying antimicrobial properties. Lentils are rich in proteins, essential amino acids, minerals, and fibers, making them a valuable source of nutrition, particularly in low and middle-income countries. Lentils have many health benefits, including positive effects on diabetes management, support for cardiovascular health, and antioxidative properties. The antioxidative properties of le...
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Rachel Alexander Abdullah Khaja Nicholas Debiec Alex Fazioli Mary Torrance Mohammed S Razzaque Source Type: research

Investigating the role of CFTR in human and mouse myometrium
CONCLUSION: These results demonstrate decreased myometrial function when CFTR is inhibited, which may have implications on pregnancy and labour outcome and therapeutic decisions for labour in CF patients.PMID:38501132 | PMC:PMC10945125 | DOI:10.1016/j.crphys.2024.100122 (Source: Physiological Research)
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Clodagh Prendergast Susan Wray Daniella Dungate Christine Martin Andra Vaida Elizabeth Brook Cecilia Ani Chioma Helen Wallace Source Type: research

Breathing patterns and associated cardiovascular changes in intermittently breathing animals: (Partially) correcting a semantic quagmire
Exp Physiol. 2024 Mar 19. doi: 10.1113/EP091784. Online ahead of print.ABSTRACTMany animal species do not breathe in a continuous, rhythmic fashion, but rather display a variety of breathing patterns characterized by prolonged periods between breaths (inter-breath intervals), during which the heart continues to beat. Examples of intermittent breathing abound across the animal kingdom, from crustaceans to cetaceans. With respect to human physiology, intermittent breathing-also termed 'periodic' or 'episodic' breathing-is associated with a variety of pathologies. Cardiovascular phenomena associated with intermittent breathin...
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Warren Burggren Andreas Fahlman William Milsom Source Type: research

Arabidopsis BECLIN1-induced autophagy mediates reprogramming in tapetal programmed cell death by altering the gross cellular homeostasis
This study demonstrates that BECN1-mediated autophagy is inhibitory to the dPCD of the tapetum, but the severity of autophagy leads to autophagic death in the later stages. The delayed and altered mode of tapetal degeneration resulted in male sterility.PMID:38503186 | DOI:10.1016/j.plaphy.2024.108471 (Source: Physiological Research)
Source: Physiological Research - March 19, 2024 Category: Physiology Authors: Surendra Pratap Singh Rishi Kumar Verma Ridhi Goel Verandra Kumar Ram Rakshpal Singh Samir V Sawant Source Type: research

Predicting Sex Differences in the Effects of Diuretics in Renal Epithelial Transport during Angiotensin II-induced Hypertension
Am J Physiol Renal Physiol. 2024 Mar 14. doi: 10.1152/ajprenal.00398.2023. Online ahead of print.ABSTRACTChronic angiotensin II (AngII) infusion is an experimental model that induces hypertension in rodents. The natriuresis, diuresis, and blood pressure responses differ between males and females. This is perhaps not unexpected, given the rodent kidney, which plays a key role in blood pressure regulation, exhibit marked sex differences. Under normotensive conditions, compared to males, the female rat nephron exhibits lower Na+/H+ exchanger 3 (NHE3) activity along the proximal tubule, but higher Na+ transporter activities al...
Source: Physiological Research - March 14, 2024 Category: Physiology Authors: Kaixin Zheng Anita T Layton Source Type: research

Predicting Sex Differences in the Effects of Diuretics in Renal Epithelial Transport during Angiotensin II-induced Hypertension
Am J Physiol Renal Physiol. 2024 Mar 14. doi: 10.1152/ajprenal.00398.2023. Online ahead of print.ABSTRACTChronic angiotensin II (AngII) infusion is an experimental model that induces hypertension in rodents. The natriuresis, diuresis, and blood pressure responses differ between males and females. This is perhaps not unexpected, given the rodent kidney, which plays a key role in blood pressure regulation, exhibit marked sex differences. Under normotensive conditions, compared to males, the female rat nephron exhibits lower Na+/H+ exchanger 3 (NHE3) activity along the proximal tubule, but higher Na+ transporter activities al...
Source: Physiological Research - March 14, 2024 Category: Physiology Authors: Kaixin Zheng Anita T Layton Source Type: research

Predicting Sex Differences in the Effects of Diuretics in Renal Epithelial Transport during Angiotensin II-induced Hypertension
Am J Physiol Renal Physiol. 2024 Mar 14. doi: 10.1152/ajprenal.00398.2023. Online ahead of print.ABSTRACTChronic angiotensin II (AngII) infusion is an experimental model that induces hypertension in rodents. The natriuresis, diuresis, and blood pressure responses differ between males and females. This is perhaps not unexpected, given the rodent kidney, which plays a key role in blood pressure regulation, exhibit marked sex differences. Under normotensive conditions, compared to males, the female rat nephron exhibits lower Na+/H+ exchanger 3 (NHE3) activity along the proximal tubule, but higher Na+ transporter activities al...
Source: Physiological Research - March 14, 2024 Category: Physiology Authors: Kaixin Zheng Anita T Layton Source Type: research

Predicting Sex Differences in the Effects of Diuretics in Renal Epithelial Transport during Angiotensin II-induced Hypertension
Am J Physiol Renal Physiol. 2024 Mar 14. doi: 10.1152/ajprenal.00398.2023. Online ahead of print.ABSTRACTChronic angiotensin II (AngII) infusion is an experimental model that induces hypertension in rodents. The natriuresis, diuresis, and blood pressure responses differ between males and females. This is perhaps not unexpected, given the rodent kidney, which plays a key role in blood pressure regulation, exhibit marked sex differences. Under normotensive conditions, compared to males, the female rat nephron exhibits lower Na+/H+ exchanger 3 (NHE3) activity along the proximal tubule, but higher Na+ transporter activities al...
Source: Physiological Research - March 14, 2024 Category: Physiology Authors: Kaixin Zheng Anita T Layton Source Type: research

Predicting Sex Differences in the Effects of Diuretics in Renal Epithelial Transport during Angiotensin II-induced Hypertension
Am J Physiol Renal Physiol. 2024 Mar 14. doi: 10.1152/ajprenal.00398.2023. Online ahead of print.ABSTRACTChronic angiotensin II (AngII) infusion is an experimental model that induces hypertension in rodents. The natriuresis, diuresis, and blood pressure responses differ between males and females. This is perhaps not unexpected, given the rodent kidney, which plays a key role in blood pressure regulation, exhibit marked sex differences. Under normotensive conditions, compared to males, the female rat nephron exhibits lower Na+/H+ exchanger 3 (NHE3) activity along the proximal tubule, but higher Na+ transporter activities al...
Source: Physiological Research - March 14, 2024 Category: Physiology Authors: Kaixin Zheng Anita T Layton Source Type: research

Periovarian Adipose Tissue - an Impact on Ovarian Functions
Physiol Res. 2024 Mar 11;73(1):1-8.ABSTRACTPeriovarian adipose tissue (POAT) is a type of gonadal white adipose tissue that surrounds the ovary. POAT is a source of various bioactive molecules, such as adipokines, cytokines, chemokines, growth factors and hormones. Thereby it could influence crucial ovarian functions. Recent findings showed that removal of POAT affects folliculogenesis and steroidogenesis in the ovary. Furthermore, changes in the morphology and function of POAT were observed in women during menopause or polycystic ovary syndrome. Although the relationship between the body's energy status and fertility in f...
Source: Physiological Research - March 11, 2024 Category: Physiology Authors: W Szyrzisko M Grzesiak Source Type: research

Sex-Linked Differences in Cardiac Atrophy After Mechanical Unloading Induced by Heterotopic Heart Transplantation
Physiol Res. 2024 Mar 11;73(1):9-25.ABSTRACTNo information is available about sex-related differences in unloading-induced cardiac atrophy. We aimed to compare the course of unloading-induced cardiac atrophy in intact (without gonadectomy) male and female rats, and in animals after gonadectomy, to obtain insight into the influence of sex hormones on this process. Heterotopic heart transplantation (HT((x)) was used as a model for heart unloading. Cardiac atrophy was assessed as the weight ratio of heterotopically transplanted heart weight (HW) to the native HW on days 7 and 14 after HTx in intact male and female rats. In se...
Source: Physiological Research - March 11, 2024 Category: Physiology Authors: D M Koles ár P Kujal I Mr ázová M Pokorn ý P Škaroupková J Sadowski L Červenka I Netuka Source Type: research