Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research
Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research
Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research
Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research
Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research
Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research
Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research
Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research
Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research
Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research
Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research
Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research
Polysome-bound mRNAs and translational mechanisms regulate drought tolerance in rice
We report differential responses of translation-associated mechanisms in rice using polysome bound mRNA sequencing at anthesis stage drought stress in resistant Apo and sensitive IR64 genotypes. Apo maintained higher polysomes with 60 S-to-40 S and polysome-to-monosome ratios which directly correlate with protein levels under stress. IR64 has less protein levels under stress due to defective translation machinery and reduced water potential. Many polysome-bound long non-coding RNAs (lncRNA) were identified in both genotypes under drought, influencing translation. Apo had higher levels of N6-Methyladenosine (m6A) mRNA modif...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Akashata Dawane Sanjay Deshpande Preethi Vijayaraghavreddy Ramu S Vemanna Source Type: research
Autonomic brain functioning and age-related health concerns
Curr Res Physiol. 2024 Mar 11;7:100123. doi: 10.1016/j.crphys.2024.100123. eCollection 2024.ABSTRACTThe autonomic nervous system (ANS) regulates involuntary bodily functions such as blood pressure, heart rate, breathing, and digestion, in addition to controlling motivation and behavior. In older adults, the ANS is dysregulated, which changes the ability of the ANS to respond to physiological signals, regulate cardiovascular autonomic functionality, diminish gastric motility, and exacerbate sleep problems. For example, a decrease in heart rate variability, or the variation in the interval between heartbeats, is one of the m...
Source: Physiological Research - March 21, 2024 Category: Physiology Authors: Amjad Z Alrosan Ghaith B Heilat Khaled Alrosan Abrar A Aleikish Aya N Rabbaa Aseel M Shakhatreh Ehab M Alshalout Enaam M A Al Momany Source Type: research
Do Longer Exhalations Increase HRV During Slow-Paced Breathing?
Appl Psychophysiol Biofeedback. 2024 Mar 20. doi: 10.1007/s10484-024-09637-2. Online ahead of print.ABSTRACTSlow-paced breathing at an individual's resonance frequency (RF) is a common element of heart rate variability (HRV) biofeedback training (Laborde et al. in Psychophysiology 59:e13952, 2022). Although there is strong empirical support for teaching clients to slow their respiration rate (RR) to the adult RF range between 4.5 and 6.5 bpm (Lehrer & Gevirtz, 2014), there have been no definitive findings regarding the best inhalation-to-exhalation (IE) ratio to increase HRV when breathing within this range. Three meth...
Source: Physiological Research - March 20, 2024 Category: Physiology Authors: Zachary M Meehan Fred Shaffer Source Type: research
