Chylothorax After Heart Surgery in Children
AbstractChylothorax is a consequence of a thoracic duct injury that can occur during surgical procedures in patients with congenital heart disease. It is associated with high rates of morbimortality and increased use of clinical and hospital resources. The aim of this study was to evaluate the risk factors, distribution, manifestations, complications, and treatments for chylothorax in patients undergoing cardiac surgery in a tertiary pediatric hospital in southern Brazil. This is a retrospective, quantitative study, in which all medical records (n  = 166) of patients with chylothorax after pediatric cardiac surgery bet...
Source: Pediatric Cardiology - August 10, 2023 Category: Cardiology Source Type: research

Patient Characteristics Associated with Hospital Admission or Antiarrhythmic Medication Changes After Emergency Department Evaluation of Supraventricular Tachycardia
ConclusionsNearly half of children treated in a pediatric ED for SVT are discharged without changes in medications. We identified patient factors associated with hospital admission or antiarrhythmic medication changes. These factors represent high value care and can be assessed when considering transfer from a referring facility. Risk stratification using these patient characteristics may reduce potentially avoidable transfers and admissions. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - August 10, 2023 Category: Cardiology Source Type: research

Tricuspid Valve Repair Can Restore the Prognosis of Patients with Hypoplastic Left Heart Syndrome and Tricuspid Valve Regurgitation: A Meta-analysis
AbstractTo date, evidence supporting the efficacy of tricuspid valve (TV) repair in interrupting the progression of systemic right ventricular (RV) adverse remodeling in hypoplastic left heart syndrome (HLHS) is conflicting. We conducted a systematic review and meta-analysis of scientific literature to assess the impact of TV repair in effectively modifying the prognosis of patients with HLHS.  We conducted a systematic review of PubMed, Web of Science, and Scopus databases. A random-effect meta-analysis was performed and transplant-free survival, freedom from TV regurgitation, and TV reoperation data were reconstructed u...
Source: Pediatric Cardiology - August 9, 2023 Category: Cardiology Source Type: research

Norwood Operation with Right Ventricular –Pulmonary Artery Shunt Versus Comprehensive Stage II After Bilateral Pulmonary Artery Banding Palliation
This study compared the operative outcomes and late hemodynamics in patients who underwent the Norwood operation, preceded by bilateral pulmonary artery banding, with a right ventricular–pulmonary artery shunt or with bidirectional Glenn anastomosis (comprehensive stage II strategy). We retrospectively reviewed 38 patients who underwent the Norwood operation preceded by bilateral pulmonary artery banding between 2004 and 2017. Of these, 17 underwent the Norwood operation with a right ventricular–pulmonary artery shunt (Group S), whereas 21 underwent the comprehensive stage II strategy (Group G). 5 years after the Nor...
Source: Pediatric Cardiology - August 9, 2023 Category: Cardiology Source Type: research

From Other Journals: A Review of Recent Articles by Our Editorial Team
AbstractIn this review, we provide a brief description of recently published articles addressing topics relevant to pediatric cardiologists. This review includes (1) Fetal diagnosis, associated anomalies, and factors affecting outcomes in fetal congenitally corrected transposition of the great arteries (ccTGA), (2) The impact of Fontan-associated liver disease on heart and heart/liver transplant, (3) 1-year outcomes of the Harmony transcatheter pulmonary valve, (4) Risk factors associated with major adverse cardiac events in patients with pulmonary atresia and intact ventricular septum undergoing intervention, and (5) Bene...
Source: Pediatric Cardiology - August 8, 2023 Category: Cardiology Source Type: research

Risk Stratification in Pediatric Wolff-Parkinson-White: Practice Variation Among Pediatric Cardiologists and Electrophysiologists
ConclusionSignificant practice variation exists in the non-invasive and invasive risk stratification of pediatric WPW, with lower concordance to published guidelines amongst PC, when compared to EP. This report highlights the need to promote awareness of current WPW guidelines in the pediatric cardiology community at large. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - August 6, 2023 Category: Cardiology Source Type: research

Aromatase Inhibitors May Increase the Risk of Cardiometabolic Complications in Adolescent Boys
ConclusionIncreased LVM, LVPWD, IVSD and Sm of patients receiving AI therapy in comparison to the control groups, and the significant correlations of these parameters with total testosterone and hemoglobin levels were determined as potential side effects of AIs. These findings emphasize the need of routine cardiac follow-up in patients using AIs. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - August 6, 2023 Category: Cardiology Source Type: research

Impact of Residual Lesion Severity on Neurodevelopmental Outcomes Following Congenital Heart Surgery in Infancy and Childhood
In conclusion, RLS 3 patients are at increased risk for neurodevelopmental delay, warranting closer follow-up and greater developmental support for cognitive, language, and motor skills soon after surgery. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - August 6, 2023 Category: Cardiology Source Type: research

Healthcare Use Among Black and White Congenital Heart Disease Medicaid Enrollees
This study examines racial differences in healthcare use among Medicaid-covered children with CHD. Using 2010 –2019 claims data from a pediatric Medicaid Accountable Care Organization, 960 Black and White children with complex CHD and ≥ 3 years of continuous Medicaid coverage were identified. Three cohorts were constructed (starting age: <  1-year-olds, 1–5-year-olds, 6–15-year-olds) and followed for 3 years. Multivariate analysis assessed annual healthcare use (cardiology, primary care, emergency department) by race, adjusting for patient and provider covariates. Overall, 51% of patients had an annual...
Source: Pediatric Cardiology - August 3, 2023 Category: Cardiology Source Type: research

Elevated Aortic Stiffness after Pediatric Heart Transplantation
AbstractIn adults, arterial stiffness has been linked to the development of target end-organ damage, thought to be related to abnormal transmission of pulse pressure. Increased arterial stiffness and endothelial dysfunction have been hypothesized to contribute to the development of microvascular dysfunction and coronary allograft vasculopathy (CAV), an important comorbidity after heart transplantation. However, little data exists regarding arterial stiffness in pediatric heart transplantation and its influence on development of coronary allograft vasculopathy is not well understood. We sought to assess aortic stiffness and...
Source: Pediatric Cardiology - August 3, 2023 Category: Cardiology Source Type: research

Correction: Novel Score to Predict Immunoglobulin Resistance in Kawasaki Disease
(Source: Pediatric Cardiology)
Source: Pediatric Cardiology - August 2, 2023 Category: Cardiology Source Type: research

A Prospective Evaluation of Arrhythmias in a Large Tertiary Neonatal Intensive Care Unit
AbstractArrhythmias in the neonatal period are common and can be classified as bradyarhythmias and tachyarrhythmias and as benign or non-benign. Neonatal arrhythmias are further differentiated between those with abnormalities in generation (non-sinus) and those with abnormalities in propagation. Because the neonatal myocardium is immature and operates at the peak of the Starling curve, significant changes in heart rate can result in a decline in cardiac output and compromise end-organ perfusion. This is especially true for premature neonates, those critically ill, or those with concomitant congenital heart disease. While s...
Source: Pediatric Cardiology - June 27, 2023 Category: Cardiology Source Type: research

Machine Learning to Predict Interstage Mortality Following Single Ventricle Palliation: A NPC-QIC Database Analysis
This study aimed to leverage advanced machine learning algorithms to optimize risk-prediction models and identify features most predictive of interstage mortality. This study utilized retrospective data from the National Pediatric Cardiology Quality Improvement Collaborative and included all patients who underwent stage I palliation and survived to hospital discharge (2008 –2019). Multiple machine learning models were evaluated, including logistic regression, random forest, gradient boosting trees, extreme gradient boost trees, and light gradient boosting machines. A total of 3267 patients were included with 208 (6.4%) i...
Source: Pediatric Cardiology - June 27, 2023 Category: Cardiology Source Type: research

Safety and Short-Term Outcomes for Infants   & lt;  2.5 kg Undergoing PDA Device Closure: A C3PO Registry Study
AbstractTo evaluate short-term procedural outcomes and safety for infants  <  2.5 kg who underwent catheterization with intended patent ductus arteriosus (PDA) device closure in a multi-center registry, as performance of this procedure becomes widespread. A multi-center retrospective review was performed using data from the Congenital Cardiac Catheterization Project on Ou tcomes (C3PO) registry. Data were collected for all intended cases of PDA closure in infants <  2.5 kg from April 2019 to December 2020 at 13 participating sites. Successful device closure was defined as device placement at the conclusion ...
Source: Pediatric Cardiology - June 27, 2023 Category: Cardiology Source Type: research