Optimal Global Longitudinal Strain Thresholds for Pediatric Heart Surgery: Insights from a University Hospital
This study marks the initial effort to establish cut-off points for preoperative GLS, postoperative GLS, and the strain index. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - March 27, 2024 Category: Cardiology Source Type: research

Natural History of Secundum ASD in Preterm and Term Neonates: A Comparative Study
AbstractAtrial septal defects  (ASDs) are common in neonates. Although past studies suggest ASDs  ≥ 3 mm in term neonates (TNs) are less likely to close, there is paucity of data regarding the natural history in preterm neonates (PNs), information that would inform surveillance. We sought to compare spontaneous closur e rates and need for intervention for ASDs in TNs/near term (≥ 36 weeks) versus PNs (<  36 weeks). We included all TNs and PNs who underwent echocardiography at ≤ 1 month between 2010 and 2018 in our institution with an ASD ≥ 3 mm, without major congenital heart disease, an...
Source: Pediatric Cardiology - March 27, 2024 Category: Cardiology Source Type: research

Impact of Abnormal Potassium on Arrhythmia Risk During Pediatric Digoxin Therapy
AbstractDigoxin is used in children with heart failure and tachyarrhythmia. Its use in patients with single ventricle anatomy has increased following evidence of improved interstage survival after the Norwood procedure. Digoxin has a narrow therapeutic window and may alter serum potassium balance, inducing arrhythmias. We hypothesized digoxin use in the setting of abnormal serum potassium levels is associated with arrhythmias. We reviewed all patients  ≤ 18 years who received digoxin while admitted at our institution from 2014 to 2021. Admissions <  2 nights were excluded. We compared patients with a hemodyna...
Source: Pediatric Cardiology - March 27, 2024 Category: Cardiology Source Type: research

Early and Long-Term Clinical Outcomes of Ductal Stenting Versus Surgical Aortopulmonary Shunt Among Young Infants with Duct-Dependent Pulmonary Circulation
AbstractSurgical aortopulmonary shunting (SAPS) and ductal stenting (DS) are the main palliations in infants with cyanotic congenital heart diseases (CHD). We aimed to study the safety and efficacy of DS and to compare it with SAPS as a palliative procedure in infants with CHD and duct-dependent pulmonary circulation. Retrospective institutional clinical data review of consecutive infants aged  <  3 months who underwent DS or SAPS over 5 years. The primary outcome was procedural success which was defined as event-free survival (mortality, need for re-intervention, procedural failure) at 30 days post-procedure. Th...
Source: Pediatric Cardiology - March 27, 2024 Category: Cardiology Source Type: research

3D Echocardiographic and Computed Tomographic Angiography Guidance for Percutaneous Closure of a Type II (Intermediate) Aortopulmonary Window
This report highlights the importance of a multimodality imaging approach to interventional procedures. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - March 27, 2024 Category: Cardiology Source Type: research

Virtual Reality Software Aids Precise Transcatheter Closure of Sinus Venosus Defect Using Covered Stent Without 3D Printing
(Source: Pediatric Cardiology)
Source: Pediatric Cardiology - March 27, 2024 Category: Cardiology Source Type: research

Quantitative Analysis of Morphology and Function in the Fetal Heart with Severe Tricuspid Regurgitation by Speckle Tracking Imaging
AbstractMorphology and function in a fetal heart with severe tricuspid regurgitation remains challenging. The aim of this study was to assess cardiac morphology and function in fetuses with severe tricuspid regurgitation by fetal heart quantification (HQ) and to assess the practical value of fetal HQ. Clinical information was analyzed for 63 pregnant women who underwent fetal cardiac ultrasonography. The women were divided into those who had a fetus with severe tricuspid regurgitation (n  = 20) and those with a normal fetus (n = 40). The global sphericity index (GSI), fractional area change (FAC), and global longit...
Source: Pediatric Cardiology - March 23, 2024 Category: Cardiology Source Type: research

Prenatal Predictors for Pulmonary Balloon Valvuloplasty in the Newborn
AbstractPulmonary balloon valvuloplasty (PBV) is the treatment of choice for subjects with isolated pulmonary valve stenosis (IPS). The purpose of this study was to define fetal echocardiographic features associated with an inpatient PBV prior to newborn hospital discharge and characterize resource utilization of IPS fetuses among participating centers. Six center, retrospective case series of singleton fetuses identified between 2010 and 2020 with IPS. Third-trimester echocardiogram data was compared with postnatal data, included pulmonary valve Doppler velocities, pulmonary valve insufficiency and ductus arteriosus flow ...
Source: Pediatric Cardiology - March 23, 2024 Category: Cardiology Source Type: research

X-ray Doses in Relation to Body Mass, Indication, and Substrate During Pediatric Electrophysiological Procedures on the Heart
AbstractThe main goal of this study is to determine typical values of dose area product (DAP) and difference in the effective dose (ED) for pediatric electrophysiological procedures on the heart in relation to patient body mass. This paper also shows DAP and ED in relation to the indication, the arrhythmia substrate determined during the procedure, and in relation to the reason for using radiation. Organ doses are described as well. The subjects were children who have had an electrophysiological study done with a 3D mapping system and X-rays in two healthcare institutions. Children with congenital heart defects were exclud...
Source: Pediatric Cardiology - March 23, 2024 Category: Cardiology Source Type: research

Development and Initial Validation of a Frailty Score for Pediatric Patients with Congenital and Acquired Heart Disease
AbstractFrailty is a multi-dimensional clinical syndrome that is associated with increased morbidity and mortality and decreased quality of life. Children/adolescents with heart disease (HD) perform significantly worse for each frailty domain compared to non-HD peers. Our study aimed to create a composite frailty score (CFS) that can be applied to children/adolescents with HD and evaluate associations between the CFS and outcomes. Children and adolescents (n = 30) with HD (73% single ventricle, 20% heart failure, 7% pulmonary hypertension) were recruited from 2016 to 2017 (baseline). Five frailty domains were assessed ...
Source: Pediatric Cardiology - March 23, 2024 Category: Cardiology Source Type: research

Effects of Implementing a Standardized Surveillance Program on Cardiac Neurodevelopmental Program Referral Completion
This study describes the successful implementation of a standardized surveillance program, including improvements to referral volume and com pletion rate. Findings also support implementation of methods that emphasize physician surveillance methods and improve accessibility for historically marginalized groups at greatest risk for disparities in access and quality of care. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - March 23, 2024 Category: Cardiology Source Type: research

Optimal Global Longitudinal Strain Thresholds for Pediatric Heart Surgery: Insights from a University Hospital
This study marks the initial effort to establish cut-off points for preoperative GLS, postoperative GLS, and the strain index. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - March 23, 2024 Category: Cardiology Source Type: research

Impact of Abnormal Potassium on Arrhythmia Risk During Pediatric Digoxin Therapy
AbstractDigoxin is used in children with heart failure and tachyarrhythmia. Its use in patients with single ventricle anatomy has increased following evidence of improved interstage survival after the Norwood procedure. Digoxin has a narrow therapeutic window and may alter serum potassium balance, inducing arrhythmias. We hypothesized digoxin use in the setting of abnormal serum potassium levels is associated with arrhythmias. We reviewed all patients  ≤ 18 years who received digoxin while admitted at our institution from 2014 to 2021. Admissions <  2 nights were excluded. We compared patients with a hemodyna...
Source: Pediatric Cardiology - March 23, 2024 Category: Cardiology Source Type: research

3D Echocardiographic and Computed Tomographic Angiography Guidance for Percutaneous Closure of a Type II (Intermediate) Aortopulmonary Window
This report highlights the importance of a multimodality imaging approach to interventional procedures. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - March 23, 2024 Category: Cardiology Source Type: research

Impact of Underweight, Overweight, and Obesity on Health-Related Quality of Life in Children with Tetralogy of Fallot Variants
AbstractTraditional cardiovascular risk factors put patients with congenital heart disease (CHD) at increased risk for cardiovascular morbidity and mortality. The aim of this study was to evaluate whether body mass index (BMI) is associated with health-related quality of life (HRQoL) in patients with variants of Tetralogy of Fallot (TOF). Patients and parents of children with variants of TOF –CHD were asked to fill out the PedsQL 4.0 questionnaire and provide weight and length. Patients were categorized into low, normal, and high BMI percentiles. Other demographic data were obtained from the Swedish national registry for...
Source: Pediatric Cardiology - March 20, 2024 Category: Cardiology Source Type: research