Risk Factors and Nomogram Model of Postoperative Delirium in Children with Congenital Heart Disease: A Single-Center Prospective Study
AbstractDelirium is a common postoperative complication in children with congenital heart disease, which affects their postoperative recovery. The purpose of this study is to explore the risk factors of delirium and construct a nomogram model to provide novel references for the prevention and management of postoperative delirium in children with congenital heart disease. 470 children after congenital heart surgery treated in the cardiac intensive care unit (CICU) of Shanghai Children ’s Medical Center were divided into a model and a validation cohort according to the principle of 7:3 distribution temporally. Then, the de...
Source: Pediatric Cardiology - January 1, 2024 Category: Cardiology Source Type: research

Higher Cumulative Dose of Opioids and Other Sedatives are Associated with Extubation Failure in Norwood Patients
ConclusionHigher cumulative opioid doses were associated with a greater incidence of extubation failure in infants post-Norwood procedure. Therefore, patients with higher cumulative doses of opioids should be more closely evaluated for extubation readiness in this population. Low end-tidal CO2 and low pulse-to-respiratory quotient were also associated with failed extubation. Consideration of the pulse-to-respiratory quotient in the extubation readiness assessment can be beneficial in the Norwood population. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - January 1, 2024 Category: Cardiology Source Type: research

Echocardiographic Mid-systolic Pulmonary Valve Notching in Extremely Low Gestational Age Neonates (ELGANs) with Severe Pulmonary Hypertension
(Source: Pediatric Cardiology)
Source: Pediatric Cardiology - January 1, 2024 Category: Cardiology Source Type: research

Perivascular Basal Echogenicity in the Fetal Heart: An Unconventional Marker of Maternal Autoimmune Antibodies
We present two cases where recognition of isolated basal echogenicity of the fetal heart, an unconventional manifestation of anti-SSA antibodies during pregnancy, led to a suspicion and ultimately diagnosis of antibody positivity in the mother. These cases highlight the importance of being aware of this rare manifestation of anti-SSA antibodies during pregnancy, as early recognition of antibody positivity may lead to improve fetal and maternal outcomes. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - January 1, 2024 Category: Cardiology Source Type: research

Letter Regarding “Ten-Year Follow-Up of Dilatation of Aortic Structures in Fallot-Type Anomalies”
(Source: Pediatric Cardiology)
Source: Pediatric Cardiology - January 1, 2024 Category: Cardiology Source Type: research

Fontan Fenestration Reduction with an Occlutech Atrial Flow Regulator: Unique Views from Three-Dimensional Intracardiac Echocardiography
We describe the use of 3D ICE in the reduction of a Fontan fenestration with an Occlutech atrial flow regulator (AFR) device. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - January 1, 2024 Category: Cardiology Source Type: research

Answer to Dr. Bassareo ’s Letter
(Source: Pediatric Cardiology)
Source: Pediatric Cardiology - January 1, 2024 Category: Cardiology Source Type: research

One-Year Follow-Up Results of MIS-C Patients with Coronary Artery Involvement: A Multi-center Study
AbstractMultisystem inflammatory syndrome (MIS-C) in children is a rare complication of SARS-CoV-2 infection. Knowing the course of the affected or unaffected coronary arteries in the patients under follow-up is important in terms of defining the long-term prognosis of the disease and determining the follow-up plan. This is a multicenter and retrospective study. The data were obtained from nine different centers. Between May 2020 and August 2022, 68 of 790 patients had coronary artery involvement. One-year echocardiographic data of 67 of 789 MIS-C patients with coronary artery involvement were analyzed. Existing pathologie...
Source: Pediatric Cardiology - December 30, 2023 Category: Cardiology Source Type: research

Inpatient Resource Utilization for Hypoplastic Left Heart Syndrome from Birth Through Fontan
AbstractCompleting 3-stage palliation for hypoplastic left heart syndrome requires significant resources. An analysis of recent data has not been performed. We aimed to determine total charges necessary to complete all 3 stages of single-ventricle palliation, including interstage encounters. We also aimed to determine overall resource utilization, including hospital days, interstage admissions, and interstage procedures. We performed a retrospective cohort study using data from the Pediatric Health Information System database between 2016 and 2021, including all patients who completed 3-stage palliation for hypoplastic lef...
Source: Pediatric Cardiology - December 30, 2023 Category: Cardiology Source Type: research

Cardiac Biomarkers Aid in Differentiation of Kawasaki Disease from Multisystem Inflammatory Syndrome in Children Associated with COVID-19
AbstractKawasaki disease (KD) and Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 show clinical overlap and both lack definitive diagnostic testing, making differentiation challenging. We sought to determine how cardiac biomarkers might differentiate KD from MIS-C. The International Kawasaki Disease Registry enrolled contemporaneous KD and MIS-C pediatric patients from 42 sites from January 2020 through June 2022. The study population included 118 KD patients who met American Heart Association KD criteria and compared them to 946 MIS-C patients who met 2020 Centers for Disease Control and Pre...
Source: Pediatric Cardiology - December 29, 2023 Category: Cardiology Source Type: research

Neonatal Outcomes of Critical Congenital Heart Defects: A Multicenter Epidemiological Study of Turkish Neonatal Society
AbstractCritical congenital heart disease (CCHD) is one of the leading causes of neonatal and infant mortality. We aimed to elucidate the epidemiology, spectrum, and outcome of neonatal CCHD in T ürkiye. This was a multicenter epidemiological study of neonates with CCHD conducted from October 2021 to November 2022 at national tertiary health centers. Data from 488 neonatal CCHD patients from nine centers were entered into the Trials-Network online registry system during the study period. Tr ansposition of great arteria was the most common neonatal CHD, accounting for 19.5% of all cases. Sixty-three (12.9%) patients had ex...
Source: Pediatric Cardiology - December 28, 2023 Category: Cardiology Source Type: research

Postoperative Morbidity and Interstage Hemodynamics Following Stage I Palliation in Patients with Turner Syndrome and Hypoplastic Left Heart Syndrome
ConclusionHigh mortality rates are described in TS  + HLHS patients following S1P. In our cohort, despite most surviving more than 30 days post-S1P, long-term survival remained poor. Interstage catheterization data suggest poor physiologic candidacy for subsequent stages of single-ventricle palliation. Understanding the clinical and hemodynamic factors related to poor outcomes in TS + HLHS will help inform management for this population. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - December 28, 2023 Category: Cardiology Source Type: research

Captopril to Lisinopril Conversion in Pediatric Cardiothoracic Surgery Patients Less Than 7  Years of Age (RISE-7)
This study evaluated safety and efficacy of converting from captopril to lisinopril in patients utilizing a pre-defined conversion of 3 mg captopril to 1 mg lisinopril. This was a single center, retrospective study including patients less than 7 years of age admitted for cardi othoracic surgery who received both captopril and lisinopril from 01/01/2017 to 06/01/2022.The primary outcome was mean change in systolic blood pressure (SBP) from baseline for 72 h after conversion of captopril to lisinopril. A total of 99 patients were enrolled. There was a significant decrease in mean SBP (99.12 mmHg vs 94.86 mmHg;p = 0...
Source: Pediatric Cardiology - December 28, 2023 Category: Cardiology Source Type: research