Obstetrics, Gynaecology and Reproductive Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Managing sepsis in pregnancy
Maternal sepsis is a major contributor to global maternal mortality. The physiological changes associated with pregnancy can obscure some of the recognised signs and symptoms of sepsis. Modified early obstetric warning score charts and sepsis screening tools aid the early identification of the septic patient. Management of maternal sepsis should involve the whole multidisciplinary team and is centred on urgent resuscitation, promt initiation of antimicrobial therapy and source control. There are logistical challenges in managing maternal sepsis in the peripartum period requiring close collaboration betwen critical care and...
Source: Obstetrics, Gynaecology and Reproductive Medicine - December 17, 2020 Category: OBGYN Authors: Prerna Mehrotra, Joel Swindin, Steve Cantellow Tags: REVIEW Source Type: research

Investigation and management of the small for gestational age fetus
The desire to identify the small for gestational age fetus is due to its association with stillbirth and poorer neonatal outcomes. The difficulty lies in determining which of these babies are just constitutionally small and healthy and which are growth restricted fetuses that are at significant risk of poor outcomes. Fetal growth restriction is often mediated through placental disease and shares a similar aetiological pathway to preeclampsia. Placental malperfusion results in impaired nutrient and oxygen delivery to the fetus. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - December 15, 2020 Category: OBGYN Authors: Si ân Bullough, Kate Navaratnam, Andrew Sharp Tags: REVIEW Source Type: research

Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a summary of the PITCHES study and its clinical implications
Intrahepatic cholestasis of pregnancy is characterized by maternal itchiness and raised maternal serum bile acids. It affects 0.7% of pregnancies in the UK and is associated with increased risk of adverse perinatal outcomes. The mainstay of treatment has been ursodeoxycholic acid, despite limited evidence for its efficacy. PITCHES is the largest randomized controlled trial to date comparing ursodeoxycholic acid with placebo in women with intrahepatic cholestasis of pregnancy, in which 605 women were randomized to active treatment or placebo. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - December 11, 2020 Category: OBGYN Authors: Jessica Fleminger, Lucy C Chappell Tags: ETHICS/EDUCATION Source Type: research

Self assessment questions
(Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - November 27, 2020 Category: OBGYN Authors: Norman Shreeve Tags: Self-Assessment Source Type: research

Editorial Board
(Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - November 27, 2020 Category: OBGYN Source Type: research

Teenage pregnancy: strategies for prevention
Teenage pregnancy is a cause and consequence of inequality, limiting the life chances of young parents and their children. It is an issue of global concern, with many countries developing programmes of prevention. This review focuses on the experience of the England strategy, launched in 1999 to address the historically high rates. It is one of the few examples of a successful long term, multi-agency programme, led by national government and locally delivered which, between 1998 and 2018, reduced the under-18 conception rate by 64%. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - November 16, 2020 Category: OBGYN Authors: Alison Hadley Tags: REVIEW Source Type: research

Fetal anomaly screening programme
The Fetal Anomaly Screening Programme (FASP) is a national antenatal screening programme, responsible for two screening pathways: Down's syndrome, Edwards' syndrome, Patau's syndrome and 11 physical conditions at the 18 –20 week scan. The core aim is to provide parents with information that supports their choices and values. In the last 19 years screening performances have improved significantly by defining a standardized approach, refining the tests offered, developing e-learning, supporting sonographers and lab oratories with a quality assurance programme (Down's syndrome screening Quality Assurance Support Service) an...
Source: Obstetrics, Gynaecology and Reproductive Medicine - November 16, 2020 Category: OBGYN Authors: Siobhan Alt, Annette McHugh, Nadia Permalloo, Pranav Pandya Tags: Ethics/education Source Type: research

Ovarian, fallopian tube and primary peritoneal cancer: an overview
Ovarian, fallopian tube and primary peritoneal cancer has the poorest survival outcomes of all gynaecological malignancies. The majority of women present with advanced stage, high grade disease following a period of generalized abdominal symptoms. There is currently no effective screening programme. Diagnosis is based on imaging and histology. Stratification of adnexal masses into benign and malignant categories has helped ensure patients are appropriately referred to the gynaecology oncology team. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - November 4, 2020 Category: OBGYN Authors: Katherine West, Jane Borley Tags: REVIEW Source Type: research

Imaging malignant gynaecological conditions
Radiology plays an essential role in the management of malignant gynaecological conditions. Multiple imaging modalities are utilized to investigate suspected gynaecological malignancy including: ultrasound, computed tomography, magnetic resonance imaging and positron emission tomography/computed tomography. Each modality has a different role in diagnosis, staging, treatment selection and follow-up. This review discusses the different imaging modalities and their recommended roles in the imaging of malignant gynaecological disease. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - October 30, 2020 Category: OBGYN Authors: Janette Smith, Helen Addley, Susan Freeman Tags: REVIEW Source Type: research

Imaging benign gynaecological conditions
Radiology plays an essential role in the management of benign gynaecological conditions and includes: ultrasound; computed tomography and magnetic resonance imaging. Each modality has a different role in diagnosis, treatment selection and follow-up. This review discusses the different imaging modalities, their recommended roles in the imaging and imaging findings of common female pelvic pathology. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - October 29, 2020 Category: OBGYN Authors: Janette Smith, Helen Addley, Susan Freeman Tags: REVIEW Source Type: research

Editorial Board
(Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - October 22, 2020 Category: OBGYN Source Type: research

Substance misuse in pregnancy
The use of psychotropic substances and nicotine during pregnancy is associated with significant harm to the pregnant woman and developing fetus. Each substance carries specific and often dose dependent effects. It is important to establish the type of substance used, the last time the substance was consumed, as well as the frequency and pattern of use. Care is best delivered through a multi-professional team with prompt interdisciplinary and inter-agency communication. Any co-existing physical or mental health needs should be addressed alongside the woman's substance misuse. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - October 16, 2020 Category: OBGYN Authors: Samantha Steele, Ruby Osorio, Louise M. Page Tags: Case-based learning Source Type: research

Self assessment questions
(Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - October 16, 2020 Category: OBGYN Authors: Norman Shreeve Tags: Self-assessment Source Type: research

Prenatal screening for common aneuploides
Down syndrome screening has been available within clinical practice for over 50 years within which time significant innovation and exciting new advances have improved the accuracy, safety, and choice for women who are considering antenatal screening for Down syndrome. The UK National Screening Committee is responsible for setting the national standards regarding screening and it has steadily and consistently directed and facilitated an increase in the detection rate whilst minimising the screen positive rate. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - October 15, 2020 Category: OBGYN Authors: Anuradha Shajpal, Farah Siddiqui Tags: Review Source Type: research

Clinical approach to recurrent pregnancy loss
Recurrent pregnancy loss is a topic that most trainee obstetricians and gynaecologists are likely to find themselves confronted with on a regular basis during their roles in early pregnancy assessment unit. We examine the current guidelines from the RCOG and ESHRE on the management of this patient group. The investigation and management of recurrent pregnancy loss is subdivided into the areas of first trimester (5 –13 weeks) and second trimester (14–24 weeks) pregnancy loss. These two areas have some overlap but generally reveal differing pathophysiology and treatment. (Source: Obstetrics, Gynaecology and Reproductive Medicine)
Source: Obstetrics, Gynaecology and Reproductive Medicine - October 13, 2020 Category: OBGYN Authors: Rebecca Shields, Amelia Hawkes, Siobhan Quenby Tags: Review Source Type: research