Assessing Acute Brain Injury after Rapid Reduction of PaCO2 using Plasma Biomarkers in Patients Undergoing ECMO
(Source: Neurocritical Care)
Source: Neurocritical Care - February 14, 2024 Category: Neurology Source Type: research
Necrotizing Pneumonia and Cerebral Air Embolism
(Source: Neurocritical Care)
Source: Neurocritical Care - February 14, 2024 Category: Neurology Source Type: research
Quantitative Pupillometry for Intracranial Pressure (ICP) Monitoring in Traumatic Brain Injury: A Scoping Review
AbstractThe neurological examination has remained key for the detection of worsening in neurocritical care patients, particularly after traumatic brain injury (TBI). New-onset, unreactive anisocoria frequently occurs in such situations, triggering aggressive diagnostic and therapeutic measures to address life-threatening elevations in intracranial pressure (ICP). As such, the field needs objective, unbiased, portable, and reliable methods for quickly assessing such pupillary changes. In this area, quantitative pupillometry (QP) proves promising, leveraging the analysis of different pupillary variables to indirectly estimat...
Source: Neurocritical Care - February 13, 2024 Category: Neurology Source Type: research
The Effect of Recruitment Maneuvers on Cerebrovascular Dynamics and Right Ventricular Function in Patients with Acute Brain Injury: A Single-Center Prospective Study
ConclusionsIn patients with acute brain injury, RMs appear to have adverse effects on cerebral hemodynamics. These findings might be partially explained by RM ’s impact on RV function. Further advanced echocardiography monitoring is required to prove this hypothesis. (Source: Neurocritical Care)
Source: Neurocritical Care - February 13, 2024 Category: Neurology Source Type: research
Aneurysmal Subdural Hematoma: A Systematic Review
ConclusionaSDH occurs infrequently. Simultaneous presence of both aSDH and aSAH from an aneurysmal source is associated with poor outcomes. Surgical treatment is associated with lower rates of unfavorable outcomes including death and severe disability. (Source: Neurocritical Care)
Source: Neurocritical Care - February 8, 2024 Category: Neurology Source Type: research
Idiosyncrasies of Outcome Grading After Brain Injury: Past into the Present
(Source: Neurocritical Care)
Source: Neurocritical Care - February 8, 2024 Category: Neurology Source Type: research
Continuous Monitoring of Cerebral Autoregulation in Adults Supported by Extracorporeal Membrane Oxygenation
ConclusionsIn ECMO patients, it is feasible to monitor CA continuously at the bedside. CA improved over time, most significantly between postcannulation days 1 and 2. CA was more impaired in VA-ECMO patients than in VV-ECMO patients. Spending less time outside MAPOPT may be associated with achieving a good neurologic outcome. (Source: Neurocritical Care)
Source: Neurocritical Care - February 7, 2024 Category: Neurology Source Type: research
Cerebral Hemodynamics and Levosimendan Use in Patients with Cerebral Vasospasm and Subarachnoid Hemorrhage: An Observational Perfusion CT-Based Imaging Study
ConclusionsIn refractory CVS, levosimendan use was associated with a significant reduction in Tmax in oligemic regions. However, this value remained at an abnormal level, indicating the presence of a persistent CVS. Further analysis raised the hypothesis that levosimendan causes cerebral vasodilation, but other studies are needed because our design does not allow us to quantify the effect of levosimendan from that of the natural evolution of CVS. (Source: Neurocritical Care)
Source: Neurocritical Care - February 7, 2024 Category: Neurology Source Type: research
Guidelines for Seizure Prophylaxis in Adults Hospitalized with Moderate –Severe Traumatic Brain Injury: A Clinical Practice Guideline for Health Care Professionals from the Neurocritical Care Society
ConclusionsBased on GRADE criteria, we suggest that ASM or no ASM may be used in patients hospitalized with moderate –severe TBI (weak recommendation, low quality of evidence). If used, we suggest LEV over PHT/fPHT (weak recommendation, very low quality of evidence) for a short duration (≤ 7 days, weak recommendation, low quality of evidence). (Source: Neurocritical Care)
Source: Neurocritical Care - February 5, 2024 Category: Neurology Source Type: research
Systemic Immune-Inflammation Response is Associated with Futile Recanalization After Endovascular Treatment
ConclusionsEarly SII elevation was associated with an increased risk of futile recanalization among patients with EVT. Our results indicated that therapeutic drug targeting hyperreactive immune-inflammation response might be helpful for reducing the incidence of futile recanalization. (Source: Neurocritical Care)
Source: Neurocritical Care - February 5, 2024 Category: Neurology Source Type: research
Correction: Broad Range Eubacterial Polymerase Chain Reaction of Cerebrospinal Fluid Reduces the Time to Exclusion of and Costs Associated with Ventriculostomy-Related Infection in Hemorrhagic Stroke
(Source: Neurocritical Care)
Source: Neurocritical Care - February 5, 2024 Category: Neurology Source Type: research
Background EEG Suppression Ratio for Early Detection of Cerebral Injury in Pediatric Cardiac Arrest
ConclusionsThe SR a sensitive and specific marker of anoxic brain injury and post-CA mortality in the pediatric population. Once detected in the post-CA setting, the 1-h SR may be a useful threshold finding for deployment of early neuroprotective strategies prior or for prompting diagnostic neuroimaging. (Source: Neurocritical Care)
Source: Neurocritical Care - February 1, 2024 Category: Neurology Source Type: research
Characterizing the Relationship Between Arterial Carbon Dioxide Trajectory and Serial Brain Biomarkers with Central Nervous System Injury During Veno-Venous Extracorporeal Membrane Oxygenation: A Prospective Cohort Study
ConclusionsAlthough rapid decreases in PaCO2 following initiation of VV-ECMO were slightly greater in patients who had CNS injuries versus those without, data overlap and absence of relationships between PaCO2 and brain biomarkers suggests other pathophysiologic variables are likely at play. (Source: Neurocritical Care)
Source: Neurocritical Care - February 1, 2024 Category: Neurology Source Type: research
Surgical Versus Dilational Tracheostomy in Patients with Severe Stroke: A SETPOINT2 Post hoc Analysis
ConclusionsIn ventilated patients with severe stroke in need of tracheostomy, surgical and dilational methods are associated with comparable decannulation rate and functional outcome at 6 months. However, ST was associated with longer time to decannulation and higher rates of early infections, supporting the dilational approach to tracheostomy in ventilated patients with stroke. (Source: Neurocritical Care)
Source: Neurocritical Care - January 30, 2024 Category: Neurology Source Type: research
The History of Donation after Circulatory Death (DCD): Backlash and Boomerang
(Source: Neurocritical Care)
Source: Neurocritical Care - January 30, 2024 Category: Neurology Source Type: research
