Pretreatment with Clodronate Improved Neurological Function by Preventing Reduction of Posthemorrhagic Cerebral Blood Flow in Experimental Subarachnoid Hemorrhage
ConclusionsOur study proposes that pretreatment with CLD-targeting PVMs can improve the prognosis of severe SAH through a candidate mechanism of inhibition of posthemorrhagic CBF reduction. (Source: Neurocritical Care)
Source: Neurocritical Care - June 12, 2023 Category: Neurology Source Type: research
The Loss of Temporal Muscle Volume is Associated with Poor Outcome in Patients with Subarachnoid Hemorrhage: An Observational Cohort Study
ConclusionsTemporal muscle volume, which is easily assessable on routine head CT scans, progressively decreases during the ICU stay after spontaneous subarachnoid hemorrhage. Because of its association with disease severity and functional outcome, it may serve as a biomarker for muscle wasting and outcome prognostication. (Source: Neurocritical Care)
Source: Neurocritical Care - June 12, 2023 Category: Neurology Source Type: research
Blood Pressure Changes in Association with Nimodipine Therapy in Patients with Spontaneous Subarachnoid Hemorrhage
ConclusionsSignificant drops in SBP occur in one third of patients after the start of IV nimodipine and after every tenth PO intake. Early recognition and counteracting with vasopressors or fluids seems necessary to prevent hypotensive episodes. (Source: Neurocritical Care)
Source: Neurocritical Care - June 12, 2023 Category: Neurology Source Type: research
Proceedings of the Fourth Regional Neurocritical Care Meeting in the Middle East and Africa in conjunction with the 19th Emirates Critical Care Conference (ECCC)
(Source: Neurocritical Care)
Source: Neurocritical Care - June 12, 2023 Category: Neurology Source Type: research
Cerebral Autoregulation: Don ’t go with the Flow, be the Flow; Author′s Response
(Source: Neurocritical Care)
Source: Neurocritical Care - June 8, 2023 Category: Neurology Source Type: research
Cerebral Autoregulation: Don ’t go with the Flow, be the Flow
(Source: Neurocritical Care)
Source: Neurocritical Care - June 8, 2023 Category: Neurology Source Type: research
Clinician-Reported Physical and Cognitive Impairments After Convulsive Status Epilepticus: Post Hoc Study of a Randomized Controlled Trial
ConclusionsIn patients attending the in-person neurologist visit on day 90 after CSE onset, ClinRO measures indicated that the main impairments were cognitive. FIM and MMSE scores were associated with GOS scores. Further studies are needed to evaluate the possible impact of neuroprotective and rehabilitation strategies on disability and cognitive impairments in survivors of CSE.Clinical trial registration NCT01359332. (Source: Neurocritical Care)
Source: Neurocritical Care - June 7, 2023 Category: Neurology Source Type: research
Considerations for Intracranial Monitoring and Surgery in Severe Traumatic Brain Injury with Temporal Lobe Contusion
(Source: Neurocritical Care)
Source: Neurocritical Care - June 7, 2023 Category: Neurology Source Type: research
Intracranial Pressure Monitoring and Management in Aneurysmal Subarachnoid Hemorrhage
AbstractAneurysmal subarachnoid hemorrhage is a medical condition that can lead to intracranial hypertension, negatively impacting patients ’ outcomes. This review article explores the underlying pathophysiology that causes increased intracranial pressure (ICP) during hospitalization. Hydrocephalus, brain swelling, and intracranial hematoma could produce an ICP rise. Although cerebrospinal fluid withdrawal via an external ventricular drain is commonly used, ICP monitoring is not always consistently practiced. Indications for ICP monitoring include neurological deterioration, hydrocephalus, brain swelling, intracranial ma...
Source: Neurocritical Care - June 6, 2023 Category: Neurology Source Type: research
Dexmedetomidine Alters the Inflammatory Profile of Rat Microglia In Vitro
ConclusionsDEX may alter the neuroinflammatory response of microglia. By altering the microglial profile, DEX may affect the progression of neurologic injury. (Source: Neurocritical Care)
Source: Neurocritical Care - June 1, 2023 Category: Neurology Source Type: research
Early Low Pulse Pressure in VA-ECMO Is Associated with Acute Brain Injury
ConclusionsEarly low pulse pressure (< 20 mm Hg) was associated with ABI in VA-ECMO patients. Low pulse pressure may serve as a marker of ABI risk, which necessitates close neuromonitoring for early detection. (Source: Neurocritical Care)
Source: Neurocritical Care - June 1, 2023 Category: Neurology Source Type: research
Prevalence of Concomitant Neurological Disorders and Long-Term Outcome of Patients Hospitalized for Intracerebral Hemorrhage with Versus without Cerebral Amyloid Angiopathy
ConclusionsAmong patients admitted for ICH, patients with CAA have lower mortality but have 2 –3 times more risk of diagnosis of epilepsy and dementia at 1 year, compared with those without CAA. (Source: Neurocritical Care)
Source: Neurocritical Care - May 31, 2023 Category: Neurology Source Type: research
A Survey of Burnout Among Neurocritical Care Practitioners
ConclusionsOur study is the first to characterize burnout among a cross-section of physicians, pharmacists, nurses, and other practitioners in the NCS. A call to action and a genuine commitment by the hospital, organizational, local, and federal governmental leaders and society as a whole is essential to advocate for interventions to ameliorate burnout and care for our health care professionals. (Source: Neurocritical Care)
Source: Neurocritical Care - May 26, 2023 Category: Neurology Source Type: research
Correction: Crosstalk Between the Nervous System and Systemic Organs in Acute Brain Injury
(Source: Neurocritical Care)
Source: Neurocritical Care - May 26, 2023 Category: Neurology Source Type: research
Effect of an Albumin Infusion Treatment Protocol on Delayed Cerebral Ischemia and Relevant Outcomes in Patients with Subarachnoid Hemorrhage
ConclusionsA management protocol based on hemodynamically oriented fluid therapy in combination with a continuous albumin infusion as the main fluid during the first 5 days of the ICU stay appears beneficial for patients with SAH because it was associated with reduced incidence of DCI and hyponatremia. Proposed mechanisms include improved hemodynamic stability that allows euvolemia and reduces the risk of ischemia, among others. (Source: Neurocritical Care)
Source: Neurocritical Care - May 25, 2023 Category: Neurology Source Type: research
