Brain Oxygenation Response to Hypercapnia in Patients with Acute Brain Injury
ConclusionsIn this study, a heterogeneous response of PbtO2 to induced hypercapnia was observed but without any deleterious elevations of intracranial pressure. (Source: Neurocritical Care)
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

Neurologic Complications in Critically Ill Patients with Toxic Alcohol Poisoning: A Multicenter Population-Based Cohort Study
ConclusionsMethanol overdose is the most common form of toxic alcohol poisoning to result in ICU admission. Poor neurologic outcomes may occur especially with methanol poisoning, with more than one in five patients dying or having persistent cognitive or visual impairment. A wide anion gap independently predicts poor outcome, emphasizing the importance of expeditious recognition and treatment. (Source: Neurocritical Care)
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

Multimodal Prediction of 3- and 12-Month Outcomes in ICU Patients with Acute Disorders of Consciousness
ConclusionsOur results indicate that EEG and fMRI features and readily available clinical data predict short-term outcome of patients with acute DoC and that EEG also predicts 12-month outcome after ICU discharge. (Source: Neurocritical Care)
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

Enhancing European Management of Analgesia, Sedation, and Delirium: A Multinational, Prospective, Interventional Before-After Trial
ConclusionsIn routine care, many patients were not assessed for PAD. Assessment rates increased significantly 1  year after the intervention.Clinical trial registration ClinicalTrials.gov: NCT03553719. (Source: Neurocritical Care)
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

Neurophysiologic Features Reflecting Brain Injury During Pediatric ECMO Support
ConclusionsIncreased seizure burden and increased interhemispheric differences in both quantitative electroencephalographic amplitude and TCD MCA TIBI scores are independently associated with acute brain injury in children undergoing ECMO support. (Source: Neurocritical Care)
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

A Solution to the Cerebral Perfusion Pressure Transducer Placement Conundrum in Neurointensive Care? The Dual Transducer
AbstractIntracranial pressure is routinely monitored in most intensive care units caring for patients with severe neurological insults and, together with continuous arterial blood pressure measurement, allows for monitoring of cerebral perfusion pressure (CPP). CPP is the driving pressure of blood flow to the brain and is used to guide therapy. However, there is considerable inconsistency in the literature regarding how CPP is technically measured and, more specifically, the appropriate placement of the arterial pressure transducer. Depending on patient positioning and where the arterial pressure transducer is placed, the ...
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

Predictors and Prognostic Impact of Hematoma Expansion in Infratentorial Cerebral Hemorrhage
ConclusionEarly presentation and presence of noncontrast computed tomography hypodensities were independent predictors of HE in infratentorial ICH, and the occurrence of HE had an independent prognostic impact in this population. (Source: Neurocritical Care)
Source: Neurocritical Care - September 5, 2023 Category: Neurology Source Type: research

Extubation After Acute Brain Injury: An Unsolved Dilemma!!
(Source: Neurocritical Care)
Source: Neurocritical Care - September 5, 2023 Category: Neurology Source Type: research

Structural Brain Injury on Brain Magnetic Resonance Imaging in Acute Respiratory Distress Syndrome
ConclusionsStructural brain injury was not uncommon among selected patients with ARDS who underwent brain MRI. The majority of brain injuries seen were bilateral globus pallidus infarcts and cerebral microbleeds. (Source: Neurocritical Care)
Source: Neurocritical Care - September 5, 2023 Category: Neurology Source Type: research

Machine Learning Algorithms to Predict Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis
This study assessed whether other machine learning (ML) models can predict DCI after SAH more accurately than conventional LR. PubMed, Embase, and Web of Science were systematically searched for studies directly comparing LR and other ML algorithms to forecast DCI in patients with SAH. Our main outcome was the accuracy measurement, represented by sensitivity, specificity, and area under the receiver operating characteristic. In the six studies included, comprising 1828 patients, about 28% (519) developed DCI. For LR models, the pooled sensitivity was 0.71 (95% confidence interval [CI] 0.57 –0.84;p <  0.01) and the...
Source: Neurocritical Care - September 5, 2023 Category: Neurology Source Type: research

Implications of Structural Brain Injury in ARDS
(Source: Neurocritical Care)
Source: Neurocritical Care - September 5, 2023 Category: Neurology Source Type: research

Response to “Temporal Muscle Atrophy: An Independent Prognosis Biomarker or Secondary to Disuse?”
(Source: Neurocritical Care)
Source: Neurocritical Care - August 31, 2023 Category: Neurology Source Type: research

Temporal Muscle Atrophy: An Independent Prognosis Biomarker or Secondary to Disuse?
(Source: Neurocritical Care)
Source: Neurocritical Care - August 31, 2023 Category: Neurology Source Type: research

Prior Thrombectomy Does Not Affect the Surgical Complication Rate of Decompressive Hemicraniectomy in Patients with Malignant Ischemic Stroke
ConclusionsA prior mechanical recanalization with possibly associated systemic thrombolysis does not affect the early surgical complication rate and the functional outcome after decompressive hemicraniectomy for malignant ischemic stroke. Patient characteristics have not changed significantly since the introduction of mechanical recanalization; therefore, the results from former large randomized controlled trials are still valid in the modern era of stroke care. (Source: Neurocritical Care)
Source: Neurocritical Care - August 28, 2023 Category: Neurology Source Type: research

Response to “Additional Associated Factors for Venous Thromboembolism in Patients with Traumatic Brain Injury”
(Source: Neurocritical Care)
Source: Neurocritical Care - August 28, 2023 Category: Neurology Source Type: research