Response to “Some Contributions on Standardized Education for Brain Death Determination”
(Source: Neurocritical Care)
Source: Neurocritical Care - September 26, 2023 Category: Neurology Source Type: research

Brazilian Contributions on Standardized Education for Brain Death Determination
(Source: Neurocritical Care)
Source: Neurocritical Care - September 26, 2023 Category: Neurology Source Type: research

Pharmacological Prevention of Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage
ConclusionsWe provide a brief overview of agents currently being studied for prevention of aVSP and DCI after aSAH. Future studies may need to identify subpopulations of patients who can benefit from these drugs and perhaps redefine acceptable outcomes to demonstrate impact. (Source: Neurocritical Care)
Source: Neurocritical Care - September 22, 2023 Category: Neurology Source Type: research

Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Behavioral Phenotyping
ConclusionsThe proposed behavioral phenotyping CDEs will assist with international harmonization of DoC studies and allow for more precise characterization of study cohorts, favorably impacting observational studies and clinical trials aimed at improving outcome in this population. (Source: Neurocritical Care)
Source: Neurocritical Care - September 19, 2023 Category: Neurology Source Type: research

Interaction of Optimal Cerebral Perfusion Pressure with Early Brain Injury and its Impact on Ischemic Complications and Outcome Following Aneurysmal Subarachnoid Hemorrhage
ConclusionsPatients with CPP near to the calculated CPPopt in the early phase after aSAH experienced less severe EBI, less frequently received decompressive hemicraniectomy, and exhibited a lower mortality rate. A prospective evaluation of CPPopt-guided management starting in the first days after ictus is needed to confirm the clinical validity of this concept. (Source: Neurocritical Care)
Source: Neurocritical Care - September 19, 2023 Category: Neurology Source Type: research

Cerebral Autoregulation Monitoring: A Guide While Navigating in Troubled Waters
(Source: Neurocritical Care)
Source: Neurocritical Care - September 19, 2023 Category: Neurology Source Type: research

Author Correction: Guidelines for Neuroprognostication in Adults with Guillain –Barré Syndrome
(Source: Neurocritical Care)
Source: Neurocritical Care - September 19, 2023 Category: Neurology Source Type: research

Cerebral Autoregulation: Igniting the Debate on Therapeutic Focus
(Source: Neurocritical Care)
Source: Neurocritical Care - September 19, 2023 Category: Neurology Source Type: research

Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Goals-of-Care and Family/Surrogate Decision-Maker Data
ConclusionsOur findings provide valuable CDEs specific to goals-of-care decisions and family/surrogate decision-making for patients with DoC that can be used to standardize studies to generate high-quality and reproducible research in this area. (Source: Neurocritical Care)
Source: Neurocritical Care - September 13, 2023 Category: Neurology Source Type: research

Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
ConclusionsThese CDEs will support progress in the field of DoC physiologic and big data and facilitate international collaboration. (Source: Neurocritical Care)
Source: Neurocritical Care - September 13, 2023 Category: Neurology Source Type: research

Early Celecoxib use in Patients with Traumatic Brain Injury
ConclusionsEarly celecoxib and ibuprofen use within 5  days post TBI was associated with higher 1-year survival probabilities and fewer complications. With emerging yet controversial preclinical evidence to suggest that COX inhibition improves TBI outcomes, this population-level study offers suggestive support for these drugs’ clinical benefit, whic h should be pursued in prospective clinical studies. (Source: Neurocritical Care)
Source: Neurocritical Care - September 13, 2023 Category: Neurology Source Type: research

Color M-mode in Transcranial Duplex Sonography: A Novel Approach for Diagnosing Right-to-Left Shunt
(Source: Neurocritical Care)
Source: Neurocritical Care - September 13, 2023 Category: Neurology Source Type: research

Clinical, Imaging Characteristics and Outcome of Intracerebral Hemorrhage Caused by Structural Vascular Lesions
ConclusionsCompared with primary ICH, ICH due to vascular lesions has smaller hematoma volume and less severe neurological deficit at presentation and better functional outcomes. (Source: Neurocritical Care)
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

Brain Oxygenation Response to Hypercapnia in Patients with Acute Brain Injury
ConclusionsIn this study, a heterogeneous response of PbtO2 to induced hypercapnia was observed but without any deleterious elevations of intracranial pressure. (Source: Neurocritical Care)
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

Neurologic Complications in Critically Ill Patients with Toxic Alcohol Poisoning: A Multicenter Population-Based Cohort Study
ConclusionsMethanol overdose is the most common form of toxic alcohol poisoning to result in ICU admission. Poor neurologic outcomes may occur especially with methanol poisoning, with more than one in five patients dying or having persistent cognitive or visual impairment. A wide anion gap independently predicts poor outcome, emphasizing the importance of expeditious recognition and treatment. (Source: Neurocritical Care)
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research