Molecules, Vol. 29, Pages 1818: Rapid and Visual Detection of Volatile Amines Based on Their Gas & ndash;Solid Reaction with Tetrachloro-p-Benzoquinone
Molecules, Vol. 29, Pages 1818: Rapid and Visual Detection of Volatile Amines Based on Their Gas–Solid Reaction with Tetrachloro-p-Benzoquinone Molecules doi: 10.3390/molecules29081818 Authors: Yue-Xiang Sun Zi-Jian Yan Wan-Xia Liu Xiao-Ming Chen Man-Hua Ding Lin-Li Tang Fei Zeng The detection of volatile amines is necessary due to the serious toxicity hazards they pose to human skin, respiratory systems, and nervous systems. However, traditional amines detection methods require bulky equipment, high costs, and complex measurements. Herein, we report a new simple, rapid, convenient, and visual...
Source: Molecules - April 17, 2024 Category: Chemistry Authors: Yue-Xiang Sun Zi-Jian Yan Wan-Xia Liu Xiao-Ming Chen Man-Hua Ding Lin-Li Tang Fei Zeng Tags: Communication Source Type: research

Molecules, Vol. 29, Pages 1817: Efficient Catalytic Degradation of Methyl Orange by Various ZnO-Doped Lignin-Based Carbons
i Wei Herein, a series of ZnO-doped lignin-based carbons (LC/ZnO) were successfully prepared from different types of lignin and used for methyl orange (MO) photocatalytic degradation. The apparent morphology, internal structure, and photoelectric properties of prepared LC/ZnO composites and their effects on subsequent MO photocatalytic degradation were investigated by various characterization techniques. The results showed that the LC/ZnO composites that were prepared in this work mainly consisted of highly dispersed ZnO nanoparticles and lignin-based carbon nano-sheets, which were beneficial for subsequent photogenera...
Source: Molecules - April 17, 2024 Category: Chemistry Authors: Zhihao Tang Yonggang Yang Weiqi Wei Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1820: Novel and Sensitive Touchdown Polymerase Chain Reaction Assays for the Detection of Goat and Sheep Milk Adulteration with Cow Milk
In this study, a specific qualitative touchdown (TD) PCR method was developed to detect the undeclared addition of cow’s milk in goat and sheep milk based on the discrimination of the peak areas of the melting curves after the modification of bovine-specific primers. The developed methodology has high specificity for the DNA templates of other species, such as buffalos and donkeys, and is able to identify the presence of cow’s milk down to 1%. Repeatability was tested at low bovine concentrations of 5% and 1% and resulted in %RSD values of 1.53–2.04 for the goat–cow a...
Source: Molecules - April 17, 2024 Category: Chemistry Authors: Ariadni Kourkouli Nikolaos Thomaidis Marilena Dasenaki Athina Markou Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1819: The Synthesis of 2 & prime;-Hydroxychalcones under Ball Mill Conditions and Their Biological Activities
Molecules, Vol. 29, Pages 1819: The Synthesis of 2′-Hydroxychalcones under Ball Mill Conditions and Their Biological Activities Molecules doi: 10.3390/molecules29081819 Authors: Imen Abid Wassim Moslah Sandrine Cojean Nicolas Imbert Philippe M. Loiseau Alain Chamayou Najet Srairi-Abid Rachel Calvet Michel Baltas Chalcones are polyphenols that belong to the flavonoids family, known for their broad pharmacological properties. They have thus attracted the attention of chemists for their obtention and potential activities. In our study, a library of compounds from 2′-hydroxychalc...
Source: Molecules - April 17, 2024 Category: Chemistry Authors: Imen Abid Wassim Moslah Sandrine Cojean Nicolas Imbert Philippe M. Loiseau Alain Chamayou Najet Srairi-Abid Rachel Calvet Michel Baltas Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1821: Molecules, Up Your Spins!
y Nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) are indispensable tools in science and medicine, offering insights into the functions of biological processes [...] (Source: Molecules)
Source: Molecules - April 17, 2024 Category: Chemistry Authors: Danila A. Barskiy Tags: Editorial Source Type: research

Molecules, Vol. 29, Pages 1801: Novel JAK Inhibitors to Reduce Graft-Versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation in a Preclinical Mouse Model
sio Jaebok Choi Allogeneic hematopoietic cell transplantation (allo-HCT) is a highly effective, well-established treatment for patients with various hematologic malignancies and non-malignant diseases. The therapeutic benefits of allo-HCT are mediated by alloreactive T cells in donor grafts. However, there is a significant risk of graft-versus-host disease (GvHD), in which the donor T cells recognize recipient cells as foreign and attack healthy organs in addition to malignancies. We previously demonstrated that targeting JAK1/JAK2, mediators of interferon-gamma receptor (IFNGR) and IL-6 receptor signaling, in donor ...
Source: Molecules - April 16, 2024 Category: Chemistry Authors: Sena Kim Peter Ruminski Megh Singh Karl Staser Kidist Ashami Julie Ritchey Sora Lim John F. DiPersio Jaebok Choi Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1803: A Novel IRAK4 Inhibitor DW18134 Ameliorates Peritonitis and Inflammatory Bowel Disease
In conclusion, our findings reported a novel IRAK4 inhibitor, DW18134, as a promising candidate for treating inflammatory diseases, including peritonitis and IBD. (Source: Molecules)
Source: Molecules - April 16, 2024 Category: Chemistry Authors: Yuqing Huang Yi Ning Zhiwei Chen Peiran Song Haotian Tang Wenhao Shi Zhipeng Wan Gege Huang Qiupei Liu Yun Chen Yu Zhou Yuantong Li Zhengsheng Zhan Jian Ding Wenhu Duan Hua Xie Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1800: Dendritic Pyridine & ndash;Imine Copper Complexes as Metallo-Drugs
Molecules, Vol. 29, Pages 1800: Dendritic Pyridine–Imine Copper Complexes as Metallo-Drugs Molecules doi: 10.3390/molecules29081800 Authors: Régis Laurent Valérie Maraval Vania Bernardes-Génisson Anne-Marie Caminade Since the discovery of cisplatin in the 1960s, the search for metallo-drugs that are more efficient than platinum complexes with negligible side effects has attracted much interest. Among the other metals that have been examined for potential applications as anticancer agents is copper. The interest in copper was recently boosted by the discovery of cuproptosis, a recently evidenced f...
Source: Molecules - April 16, 2024 Category: Chemistry Authors: R égis Laurent Val érie Maraval Vania Bernardes-G énisson Anne-Marie Caminade Tags: Review Source Type: research

Molecules, Vol. 29, Pages 1804: Enzymatic Assembly of Chitosan-Based Network Polysaccharides and Their Encapsulation and Release of Fluorescent Dye
In this study, the enzymatic elongation of amylose chains on chitosan-based network polysaccharides by glucan phosphorylase (GP) catalysis was performed to obtain assembly materials. Maltoheptaose (Glc7) primers for GP-catalyzed enzymatic polymerization were first introduced into WSCS by reductive amination. Crosslinking of the product with the above-mentioned crosslinker by condensation was then performed to produce Glc7-modified network polysaccharides. The GP-catalyzed enzymatic polymerization of the α-d-glucose 1-phosphate monomer from the Glc7 primers on the network polysaccharides was conducted, where t...
Source: Molecules - April 16, 2024 Category: Chemistry Authors: Masayasu Totani Aina Nakamichi Jun-ichi Kadokawa Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1805: Hierarchically Structured Graphene Aerogel Supported Nickel & ndash;Cobalt Oxide Nanowires as an Efficient Electrocatalyst for Oxygen Evolution Reaction
Molecules, Vol. 29, Pages 1805: Hierarchically Structured Graphene Aerogel Supported Nickel–Cobalt Oxide Nanowires as an Efficient Electrocatalyst for Oxygen Evolution Reaction Molecules doi: 10.3390/molecules29081805 Authors: Donglei Guo Jiaqi Xu Guilong Liu Xu Yu The rational design of a heterostructure electrocatalyst is an attractive strategy to produce hydrogen energy by electrochemical water splitting. Herein, we have constructed hierarchically structured architectures by immobilizing nickel–cobalt oxide nanowires on/beneath the surface of reduced graphene aerogels (NiCoO2/rGAs) ...
Source: Molecules - April 16, 2024 Category: Chemistry Authors: Donglei Guo Jiaqi Xu Guilong Liu Xu Yu Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1806: Secondary Atomization and Micro-Explosion Effect Induced by Surfactant and Nanoparticles on Enhancing the Combustion Performance of Al/JP-10/OA Nanofluid Fuel
g Dan Luo Aluminum/tetrahydrodicyclopentadiene/oleic acid (Al/JP-10/OA) nanofluid fuel is considered a potential fuel for aircraft powered by aviation turbine engines. However, an optimized formula for an Al/JP-10/OA system inducing a secondary atomization and micro-explosion effect and improving the burning performance needs to be developed. With this aim, in this work, the combustion characteristics of pure JP-10, JP-10/OA, JP-10/Al, and Al/JP-10/OA were experimentally tested, and a comparative analysis was conducted. Specifically, the influence of the surfactant and nanoparticle concentrations on the combustion ch...
Source: Molecules - April 16, 2024 Category: Chemistry Authors: Shengji Li Zixuan Liu Qianmei Yang Zhangtao Wang Xuefeng Huang Dan Luo Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1807: Anticancer Effects of Abietane Diterpene 7 & alpha;-Acetoxy-6 & beta;-hydroxyroyleanone from Plectranthus grandidentatus and Its Semi-Synthetic Analogs: An In Silico Computational Approach
Molecules, Vol. 29, Pages 1807: Anticancer Effects of Abietane Diterpene 7α-Acetoxy-6β-hydroxyroyleanone from Plectranthus grandidentatus and Its Semi-Synthetic Analogs: An In Silico Computational Approach Molecules doi: 10.3390/molecules29081807 Authors: Vera M. S. Isca Przemysław Sitarek Anna Merecz-Sadowska Magdalena Małecka Monika Owczarek Joanna Wieczfińska Radosław Zajdel Paweł Nowak Patricia Rijo Tomasz Kowalczyk The abietane diterpenoid 7α-acetoxy-6β-hydroxyroyleanone (Roy) isolated from Plectranthus grandidentatus demonstrates cytotoxicit...
Source: Molecules - April 16, 2024 Category: Chemistry Authors: Vera M. S. Isca Przemys ław Sitarek Anna Merecz-Sadowska Magdalena Ma łecka Monika Owczarek Joanna Wieczfi ńska Rados ław Zajdel Pawe ł Nowak Patricia Rijo Tomasz Kowalczyk Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1808: Synthesis, Cytotoxicity, and Photophysical Investigations of 2-Amino-4,6-diphenylnicotinonitriles: An Experimental and Theoretical Study
In this study, we present a comprehensive investigation of 2-amino-4,6-diphenylnicotinonitriles (APNs, 1–6), including their synthesis, cytotoxicity against breast cancer cell lines, and photophysical properties. Compound 3 demonstrates exceptional cytotoxicity, surpassing the potency of Doxorubicin. The fluorescence spectra of the synthesized 1–6 in different solvents reveal solvent-dependent shifts in the emission maximum values, highlighting the influence of the solvent environment on their fluorescence properties. A quantum chemical TD-DFT analysis provides insights into the electronic struc...
Source: Molecules - April 16, 2024 Category: Chemistry Authors: Alwah R. Al-Ghamdi Shofiur Rahman Reem I. Al-Wabli Maha S. Al-Mutairi A. F. M. Motiur Rahman Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1809: Zanthoxylum bungeanum Waste-Derived High-Nitrogen Self-Doped Porous Carbons as Efficient Adsorbents for Methylene Blue
This study offers a new approach for the cost-effective design of nitrogen self-doped porous carbons, facilitating the efficient removal of MB from wastewater. (Source: Molecules)
Source: Molecules - April 16, 2024 Category: Chemistry Authors: Yuhong Zhao Qi Zhang Zhuhua Gong Wenlin Zhang Yun Ren Qiang Li Hongjia Lu Qinhong Liao Zexiong Chen Jianmin Tang Tags: Article Source Type: research

Molecules, Vol. 29, Pages 1810: Physicochemical Characterization, Antioxidant and Anticancer Activity Evaluation of an Acidic Polysaccharide from Alpinia officinarum Hance
ing Zhang Jian Xu AHP-3a, a triple-helix acidic polysaccharide isolated from Alpinia officinarum Hance, was evaluated for its anticancer and antioxidant activities. The physicochemical properties and structure of AHP-3a were investigated through gel permeation chromatography, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, and nuclear magnetic resonance (NMR) spectroscopy. The weight-average molecular weight of AHP-3a was 484 kDa, with the molar percentages of GalA, Gal, Ara, Xyl, Rha, Glc, GlcA, and Fuc being 35.4%, 21.4%, 16.9%, 11.8%, 8.9%, 3.1%, 2.0%, and 0.5%, respectively. Based on ...
Source: Molecules - April 16, 2024 Category: Chemistry Authors: Huan Wen Yangjun Kuang Xiuxia Lian Hailong Li Mingyan Zhou Yinfeng Tan Xuguang Zhang Yipeng Pan Junqing Zhang Jian Xu Tags: Article Source Type: research