Molecules, Vol. 29, Pages 1740: Phytochemical Composition and Antimicrobial Properties of New Lavandula angustifolia Ecotypes
szewski
Piotr Borysiuk
The purpose of this study was to characterize ethanol extracts from leaves and flowers of two ecotypes (PL—intended for industrial plantations and KC—intended for cut flowers) of Lavandula angustifolia Mill. The plant was cultivated in 2019 in southern Poland as part of a long-term research plan to develop new varieties resistant to difficult environmental conditions. The collected leaves and flowers were used to prepare ethanol extracts, which were then analyzed in terms of phytochemical composition and antioxidant, bactericidal, and fungicidal properties. Using UPL...
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Izabela Betlej Bogus ław Andres Tomasz Cebulak Ireneusz Kapusta Maciej Balawejder Natalia Żurek S ławomir Jaworski Agata Lange Marta Kutwin El żbieta Pisulewska Agnieszka Kidacka Barbara Krochmal-Marczak Piotr Boruszewski Piotr Borysiuk Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1744: Interzeolite Transformation from FAU-to-EDI Type of Zeolite
This study reports for the first time the transformation of the pre-made FAU type of zeolite to the EDI type of zeolite. The concentration of the KOH solution controls this interzeolite transformation, which unusually occurs at both room temperature and under hydrothermal conditions. The transformation involves the amorphization and partial dissolution of the parent FAU phase, followed by the crystallization of EDI zeolite. At room temperature, the transformation (11–35 days) provides access to well-shaped nano-sized crystals and hollow hierarchical particles while the hydrothermal synthesis results in faster...
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Stanislav Ferdov Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1721: Study of CHF3/CH2F2 Adsorption Separation in TIFSIX-2-Cu-i
In this study, the adsorption mechanism of CHF3–CH2F2 mixtures in TIFSIX-2-Cu-i was revealed at the microscopic level by combining static pure-component adsorption experiments, molecular simulations, and density-functional theory (DFT) calculations. The adsorption separation selectivity of CH2F2/CHF3 in TIFSIX-2-Cu-i is 3.17 at 3 bar under 308 K. The existence of similar TiF62− binding sites for CH2F2 or CHF3 was revealed in TIFSIX-2-Cu-i. Interactions between the fluorine atom of the framework and the hydrogen atom of the guest molecule were found to be responsible for determining the high adso...
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Shoudong Wang Lei Zhou Hongyun Qin Zixu Dong Haoyuan Li Bo Liu Zhilu Wang Lina Zhang Qiang Fu Xia Chen Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1722: Mineral Acid Co-Extraction in Reactive Extraction of Lactic Acid Using a Thymol-Menthol Deep Eutectic Solvent as a Green Modifier
In conclusion, the selected solvent phase composition and mineral acid influence the co-extraction and, thus, final product purity. The successful application of the natural deep eutectic solvent as the modifier enhances the sustainability of liquid–liquid extraction processes. (Source: Molecules)
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Paul Demmelmayer Marija Ćosić Marlene Kienberger Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1723: Copper(I) Iodide Thin Films: Deposition Methods and Hole-Transporting Performance
ner
The pursuit of p-type semiconductors has garnered considerable attention in academia and industry. Among the potential candidates, copper iodide (CuI) stands out as a highly promising p-type material due to its conductivity, cost-effectiveness, and low environmental impact. CuI can be employed to create thin films with >80% transparency within the visible range (400–750 nm) and utilizing various low-temperature, scalable deposition techniques. This review summarizes the deposition techniques for CuI as a hole-transport material and their performance in perovskite solar cells, thin-film tran...
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Mahboubeh Jamshidi James M. Gardner Tags: Review Source Type: research
Molecules, Vol. 29, Pages 1724: New Findings on the Crystal Polymorphism of Imepitoin
Renato Molteni
Scientific and industrial reasons dictate the study of the solid state of imepitoin, a highly safe and tolerable anticonvulsant drug used in the therapy of epileptic dogs that was approved in the Europe Union in 2013. Our investigations allowed us to discover the existence of a new polymorph of imepitoin, which finds itself in a monotropic relationship with the crystalline form (polymorph I) already known and present on the market. This form (polymorph II), obtained by crystallization from xylene, remains metastable under ambient conditions for at least 1 year. Both solid forms were characterized by the...
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Giovanna Bruni Doretta Capsoni Anna Pellegrini Angela Altomare Mauro Coduri Chiara Ferrara Pietro Galinetto Renato Molteni Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1725: Study on the Synthesis, Surface Activity, and Self-Assembly Behavior of Anionic Non-Ionic Gemini Surfactants
This article proposes a simple and effective synthesis method, using 3-aminopropane sulfonic acid, fatty alcohol polyoxyethylene ether, and epichlorohydrin as raw materials, to insert EO into hydrophobic alkyl chains and synthesize a series of new anionic non-ionic Gemini surfactants (CnEO-5, n = 8, 12, 16). The surface activity, thermodynamic properties, and self-assembly behavior of these surfactants were systematically studied through surface tension, conductivity, steady-state fluorescence probes, transmission electron microscopy, and molecular dynamics simulations. The surface tension test results show that CnEO-5 has...
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Zhiqiang Man Wenxiang Wu Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1720: Rapid Apta-Chromogenic Detection Method for Nitrofuran Metabolite Determination
Unajak
Nitrofuran (NF) contamination in food products is a global problem resulting in the banned utilization and importation of nitrofuran contaminated products. A novel chromogenic detection method using a specific DNA aptamer with high affinity and specificity to nitrofurans was developed. Single-stranded DNA aptamers specific to nitrofuran metabolites, including 3-amino-2-oxazolidinone (AOZ), 3-amino-5-methylmorpholino-2-oxazolidinone (AMOZ), and 1-aminohydantoin (AHD), were isolated using magnetic bead-SELEX. The colorimetric detection of nitrofurans using gold nanoparticles (AuNPs) exhibited an AOZ detection ran...
Source: Molecules - April 10, 2024 Category: Chemistry Authors: Navarat Chaisri Chutikarn Jaengphop Ikuo Hirono Sasimanas Unajak Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1719: The Piezocatalytic Degradation of Sulfadiazine by Lanthanum-Doped Barium Titanate
Shiyang Li
Piezocatalysis, a heterogeneous catalytic technique, leverages the periodic electric field changes generated by piezoelectric materials under external forces to drive carriers for the advanced oxidation of organic pollutants. Antibiotics, as emerging trace organic pollutants in water sources, pose a potential threat to animals and drinking water safety. Thus, piezoelectric catalysis can be used to degrade trace organic pollutants in water. In this work, BaTiO3 and La-doped BaTiO3 were synthesized using an improved sol–gel–hydrothermal method and used as piezocatalytic materials t...
Source: Molecules - April 10, 2024 Category: Chemistry Authors: Daijun Meng Yuqi Xiang Ziwei Yang Hao Yuan Liang Tang Shiyang Li Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1704: Impact of Backbone Substitution on Organocatalytic Activity of Sterically Encumbered NHC in Benzoin Condensation
In this study, we provide a theoretical explanation for the experimentally observed decrease in the organocatalytic activity of N-aryl imidazolylidenes methylated at the C4/5-H positions in the benzoin condensation of aromatic aldehydes. A comparative quantum chemical study of energy profiles for the NHC-mediated benzoin condensation of furfural has revealed a high energy barrier to the formation of the IPrMe-based furanic Breslow intermediate that can be attributed to the negative steric interactions between the imidazole backbone methyl groups and N-aryl substituents. (Source: Molecules)
Source: Molecules - April 10, 2024 Category: Chemistry Authors: Rinat R. Aysin Konstantin I. Galkin Tags: Communication Source Type: research
Molecules, Vol. 29, Pages 1705: Injectable Hydrogels Based on Hyaluronic Acid and Gelatin Combined with Salvianolic Acid B and Vascular Endothelial Growth Factor for Treatment of Traumatic Brain Injury in Mice
Haitong Wan
Traumatic brain injury (TBI) leads to structural damage in the brain, and is one of the major causes of disability and death in the world. Herein, we developed a composite injectable hydrogel (HA/Gel) composed of hyaluronic acid (HA) and gelatin (Gel), loaded with vascular endothelial growth factor (VEGF) and salvianolic acid B (SAB) for treatment of TBI. The HA/Gel hydrogels were formed by the coupling of phenol-rich tyramine-modified HA (HA-TA) and tyramine-modified Gel (Gel-TA) catalyzed by horseradish peroxidase (HRP) in the presence of hydrogen peroxide (H2O2). SEM results showed that HA/Gel hydrogel...
Source: Molecules - April 10, 2024 Category: Chemistry Authors: Guoying Zhou Yajie Cao Yujia Yan Haibo Xu Xiao Zhang Tingzi Yan Haitong Wan Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1706: Temperature-Controlled Divergent Synthesis of Pyrazoles and 1-Tosyl-1H-pyrazoles under Transition-Metal-Catalyst- and Oxidant-Free Conditions
ing Cao
Herein, a general and practical temperature-controlled approach for the divergent synthesis of pyrazoles and 1-tosyl-1H-pyrazoles via electrophilic cyclization in the absence of transition-metal catalysts and oxidants was developed. The desired products were obtained in moderate to excellent yields from common starting materials in both ionic liquids and ethanol by simply tuning the reaction temperature. This strategy employs easily synthesized substrates, mild reaction conditions, and excellent functional-group tolerance. (Source: Molecules)
Source: Molecules - April 10, 2024 Category: Chemistry Authors: Kai Wang Wenjing Xu Chengcai Xia Xianting Cao Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1707: Starch from Unripe Apples (Malus domestica Borkh) as an Alternative for Application in the Food Industry
This study investigated the properties of starch isolated from the unripe fruit of two apple cultivars (Malus domestica Borkh) grown in southern Poland (Central Europe). The chemical composition of both starches, molecular mass, their granulation, thermal characteristics, swelling characteristics, and rheological characteristics were studied. The starches differed significantly in ash, phosphorus, and protein content. The water-binding capacity at temperatures of 25–65 °C was similar, while differences of 20% appeared at higher temperatures. In contrast, a significant difference was found in the s...
Source: Molecules - April 10, 2024 Category: Chemistry Authors: Dorota Gumul Jaros ław Korus Magdalena Orczykowska Justyna Rosicka-Kaczmarek Joanna Oracz Anna Areczuk Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1708: Antitumoral Activity of the Universal Methyl Donor S-Adenosylmethionine in Glioblastoma Cells
We report here for the first time that AdoMet selectively inhibited the viability and proliferation of U87MG, U343MG, and U251MG GBM cells. In these cell lines, AdoMet induced S and G2/M cell cycle arrest and apoptosis and downregulated the expression and activation of proteins involved in homologous recombination DNA repair, including RAD51, BRCA1, and Chk1. Furthermore, AdoMet was able to maintain DNA in a damaged state, as indicated by the increased γH2AX/H2AX ratio. AdoMet promoted mitotic catastrophe through inhibiting Aurora B kinase expression, phosphorylation, and localization causing GBM cells to und...
Source: Molecules - April 10, 2024 Category: Chemistry Authors: Laura Mosca Cristina Pagano Roberta Veglia Tranchese Roberta Grillo Francesca Cadoni Giovanna Navarra Laura Coppola Martina Pagano Luigi Mele Giovanna Cacciapuoti Chiara Laezza Marina Porcelli Tags: Article Source Type: research
Molecules, Vol. 29, Pages 1710: A Novel Cocrystal of Daidzein with Piperazine to Optimize the Solubility, Permeability and Bioavailability of Daidzein
uanhua Du
Yang Lu
It is well known that daidzein has various significant medicinal values and health benefits, such as anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, cholesterol lowering, neuroprotective, cardioprotective and so on. To our disappointment, poor solubility, low permeability and inferior bioavailability seriously limit its clinical application and market development. To optimize the solubility, permeability and bioavailability of daidzein, the cocrystal of daidzein and piperazine was prepared through a scientific and reasonable design, which was thoroughly characterized by single-crystal X...
Source: Molecules - April 10, 2024 Category: Chemistry Authors: Zhipeng Wang Shuang Li Qi Li Wenwen Wang Meiru Liu Shiying Yang Li Zhang Dezhi Yang Guanhua Du Yang Lu Tags: Article Source Type: research
