Correction: Circular RNA circCORO1C promotes laryngeal squamous cell carcinoma progression by modulating the let-7c-5p/PBX3 axis
(Source: Molecular Cancer)
Source: Molecular Cancer - March 15, 2023 Category: Cancer & Oncology Authors: Yongyan Wu, Yuliang Zhang, Xiwang Zheng, Fengsheng Dai, Yan Lu, Li Dai, Min Niu, Huina Guo, Wenqi Li, Xuting Xue, Yunfeng Bo, Yujia Guo, Jiangbo Qin, Yixiao Qin, Hongliang Liu, Yu Zhang & hellip; Tags: Correction Source Type: research
Correction: Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation
(Source: Molecular Cancer)
Source: Molecular Cancer - March 14, 2023 Category: Cancer & Oncology Authors: Jonas Wei ße, Julia Rosemann, Lisa Müller, Matthias Kappler, Alexander W. Eckert, Markus Glaß, Danny Misiak, Stefan Hüttelmaier, Wolfgang G. Ballhausen, Mechthild Hatzfeld, Monika Haemmerle and Tony Gutschner Tags: Correction Source Type: research
Hypoxia and HIFs in Ewing sarcoma: new perspectives on a multi-facetted relationship
Hypoxia develops during the growth of solid tumors and influences tumoral activity in multiple ways. Low oxygen tension is also present in the bone microenvironment where Ewing sarcoma (EwS) – a highly aggress... (Source: Molecular Cancer)
Source: Molecular Cancer - March 13, 2023 Category: Cancer & Oncology Authors: A. Katharina Ceranski, Martha J. Carre ño-Gonzalez, Anna C. Ehlers, Maria Vittoria Colombo, Florencia Cidre-Aranaz and Thomas G. P. Grünewald Tags: Review Source Type: research
Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments
The malignant tumor is a multi-etiological, systemic and complex disease characterized by uncontrolled cell proliferation and distant metastasis. Anticancer treatments including adjuvant therapies and targeted... (Source: Molecular Cancer)
Source: Molecular Cancer - March 11, 2023 Category: Cancer & Oncology Authors: Zhennan Yuan, Yingpu Li, Sifan Zhang, Xueying Wang, He Dou, Xi Yu, Zhiren Zhang, Shanshan Yang and Min Xiao Tags: Review Source Type: research
Correction: Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity
(Source: Molecular Cancer)
Source: Molecular Cancer - March 8, 2023 Category: Cancer & Oncology Authors: Ho Jin Lee, Phuong Chi Pham, Seung Yeob Hyun, Byungyeob Baek, Byungjin Kim, Yunha Kim, Hye-Young Min, Jeeyeon Lee and Ho-Young Lee Tags: Correction Source Type: research
The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers
PIWI proteins have a strong correlation with PIWI-interacting RNAs (piRNAs), which are significant in development and reproduction of organisms. Recently, emerging evidences have indicated that apart from the ... (Source: Molecular Cancer)
Source: Molecular Cancer - March 7, 2023 Category: Cancer & Oncology Authors: Qun Zhang, Yazhi Zhu, Xinyu Cao, Wenhui Tan, Jianglong Yu, Yaqiong Lu, Ran Kang, Xiaolan Wang and Ermao Li Tags: Review Source Type: research
Cuproptosis: mechanisms and links with cancers
Cuproptosis was a copper-dependent and unique kind of cell death that was separate from existing other forms of cell death. The last decade has witnessed a considerable increase in investigations of programmed... (Source: Molecular Cancer)
Source: Molecular Cancer - March 7, 2023 Category: Cancer & Oncology Authors: Jiaming Xie, Yannan Yang, Yibo Gao and Jie He Tags: Review Source Type: research
New frontiers in immune checkpoint B7-H3 (CD276) research and drug development
B7-H3 (CD276), a member of the B7 family of proteins, is a key player in cancer progression. This immune checkpoint molecule is selectively expressed in both tumor cells and immune cells within the tumor micro... (Source: Molecular Cancer)
Source: Molecular Cancer - March 2, 2023 Category: Cancer & Oncology Authors: Ayechew Adera Getu, Abiye Tigabu, Ming Zhou, Jianrong Lu, Øystein Fodstad and Ming Tan Tags: Review Source Type: research
CD39/CD73/A2AR pathway and cancer immunotherapy
Cancer development is closely associated with immunosuppressive tumor microenvironment (TME) that attenuates antitumor immune responses and promotes tumor cell immunologic escape. The sequential conversion of ... (Source: Molecular Cancer)
Source: Molecular Cancer - March 2, 2023 Category: Cancer & Oncology Authors: Chenglai Xia, Shuanghong Yin, Kenneth K. W. To and Liwu Fu Tags: Review Source Type: research
LncRNA-BC069792 suppresses tumor progression by targeting KCNQ4 in breast cancer
Breast cancer is the most common malignant tumor that threatens women's health. Attention has been paid on the study of long- non-coding RNA (lncRNA) in breast cancer. However, the specific mechanism remains n... (Source: Molecular Cancer)
Source: Molecular Cancer - March 1, 2023 Category: Cancer & Oncology Authors: Yunxiang Zhang, Xiaotong Dong, Xiangyu Guo, Chunsen Li, Yanping Fan, Pengju Liu, Dawei Yuan, Xialin Ma, Jingru Wang, Jie Zheng, Hongli Li and Peng Gao Tags: Research Source Type: research
m6A methylation: a process reshaping the tumour immune microenvironment and regulating immune evasion
N6-methyladenosine (m6A) methylation is the most universal internal modification in eukaryotic mRNA. With elaborate functions executed by m6A writers, erasers, and readers, m6A modulation is involved in myriad ph... (Source: Molecular Cancer)
Source: Molecular Cancer - March 1, 2023 Category: Cancer & Oncology Authors: Xiaoxue Cao, Qishun Geng, Danping Fan, Qiong Wang, Xing Wang, Mengxiao Zhang, Lu Zhao, Yi Jiao, Tingting Deng, Honglin Liu, Jing Zhou, Liqun Jia and Cheng Xiao Tags: Review Source Type: research
Targeting RNA N6-methyladenosine to synergize with immune checkpoint therapy
Cancer immunotherapy, especially immune checkpoint therapy, has revolutionized therapeutic options by reactivating the host immune system. However, the efficacy varies, and only a small portion of patients dev... (Source: Molecular Cancer)
Source: Molecular Cancer - February 21, 2023 Category: Cancer & Oncology Authors: Xianyong Zhou, Chen Li, Tong Chen, Wenhao Li, Xiaolong Wang and Qifeng Yang Tags: Review Source Type: research
Liquid biopsy at the frontier in renal cell carcinoma: recent analysis of techniques and clinical application
Renal cell carcinoma (RCC) is a major pathological type of kidney cancer and is one of the most common malignancies worldwide. The unremarkable symptoms of early stages, proneness to postoperative metastasis o... (Source: Molecular Cancer)
Source: Molecular Cancer - February 21, 2023 Category: Cancer & Oncology Authors: Mingyang Li, Lei Li, Jianyi Zheng, Zeyu Li, Shijie Li, Kefeng Wang and Xiaonan Chen Tags: Review Source Type: research
Cross-talk between cancer stem cells and immune cells: potential therapeutic targets in the tumor immune microenvironment
Ongoing research has revealed that the existence of cancer stem cells (CSCs) is one of the biggest obstacles in the current cancer therapy. CSCs make an influential function in tumor progression, recurrence an... (Source: Molecular Cancer)
Source: Molecular Cancer - February 21, 2023 Category: Cancer & Oncology Authors: Bo Wu, Xiang Shi, Meixi Jiang and Hongxu Liu Tags: Review Source Type: research
SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities
Hematological malignancies are a highly heterogeneous group of diseases with varied molecular and phenotypical characteristics. SWI/SNF (SWItch/Sucrose Non-Fermentable) chromatin remodeling complexes play sign... (Source: Molecular Cancer)
Source: Molecular Cancer - February 21, 2023 Category: Cancer & Oncology Authors: Alvaro Andrades, Paola Peinado, Juan Carlos Alvarez-Perez, Juan Sanjuan-Hidalgo, Daniel J. Garc ía, Alberto M. Arenas, Ana M. Matia-González and Pedro P. Medina Tags: Review Source Type: research
