Cranial Magnetic Resonance Imaging Findings in Hypotonic Infants with Cobalamin Deficiency and Combined Methylmalonic Aciduria and Homocystinuria
Klin Padiatr DOI: 10.1055/a-1749-6008Vitamin B12 begins to accumulate in infants within the first six months while mothers often remain asymptomatic and infantile vitamin B12 deficiency may not be noticed until the onset of neurological effects. In infants with Cbl deficiency, long-term exposure to elevated methylmalonic acid and homocysteine (MMA-HC) may have toxic effects on the central nervous system. The aim of this study was to evaluate cranial magnetic resonance (MRI) findings of 23 hypotonic infants that were followed up with a diagnosis of nutritional Cbl ...
Source: Klinische Padiatrie - February 24, 2022 Category: Pediatrics Authors: Dilber, Beril Ey üboğlu, İlker Tags: Original Article Source Type: research

Solide pseudopapill äre Pankreasneoplasie bei Kindern und Jugendlichen
Klin Padiatr DOI: 10.1055/a-1733-2229 Hintergrund Pankreastumore im Kindes- und Jugendalter sind seltene Entitäten, die lange Zeit asymptomatisch verlaufen und häufig als Zufallsbefund bei bildgebenden Untersuchungen aus anderen Gründen oder durch abdominelle Schmerzen auffallen. Solide pseudopapilläre Pankreasneoplasien (SPN) sind seltene Vertreter dieser Gruppe. Die Therapie der SPN besteht in der primären R0 Resektion. Wir stellen vier Fälle von SPN vor und diskutieren das individualisierte diagnostische und therapeutische Vorgehen. Me...
Source: Klinische Padiatrie - February 21, 2022 Category: Pediatrics Authors: Madadi-Sanjani, Omid Z öller, Christoph Beilken, Andreas Pfister, Eva-Doreen Sander, Bj örn Ure, Benno Dingemann, Jens Tags: Originalarbeit Source Type: research

Complementary and Integrative Medicine in Pediatric Oncology – Development and Evaluation of a Blended Learning Program
Conclusion Following the end of the blended learning program the e-learning was made available again for interested POs. 34 further applications were received for participation in this part of the training program. With around 300 POs in Germany, this shows a high demand for further training offers of this kind as well as a need for further development. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - February 21, 2022 Category: Pediatrics Authors: Reis, Daniela G üthlin, Corina Engler, Jennifer Schildmann, Jan Hilje, Clara Carvalho Mach, Nicolas Molleker, Christina L ängler, Alfred Tags: Original Article Source Type: research

Early Neurologic Complications and Long-term Neurologic Outcomes of Extracorporeal Membrane Oxygenation Performed in Children
Conclusion Children who receive ECMO have a risk to develop ANC, which was related to the length of ECMO treatment, while survival was related to less organ failure, Long-term neurological outcome was good in our patient cohort. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - February 21, 2022 Category: Pediatrics Authors: Azapagasi, Ebru Kendirli, Tan ıl Tun çer, Gokcen Oz Perk, Oktay Isikhan, Selen Yilmaz T ıras, Serap Teber Eyileten, Zeynep Ince, Erdal Uysalel, Adnan Akar, Ahmet R üçhan Tags: Original Article Source Type: research

Correction: Myocardial Ischemia in a Preterm Born Baby
Klin Padiatr DOI: 10.1055/a-1765-7203 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - February 17, 2022 Category: Pediatrics Authors: Poryo, Martin Hess, Steffi Stock, Lilly Ruffing, Sarah Zemlin, Michael Meyer, Sascha Tags: Erratum Source Type: research

Correction: Does Metformin Treatment in Pediatric Population Cause Vitamin B12 Deficiency?
Klin Padiatr DOI: 10.1055/a-1766-2824 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - February 16, 2022 Category: Pediatrics Authors: Ta ş, Özen Kontbay, Tugba Dogan, Ozlem Kose, Engin Berberoglu, Merih Siklar, Zeynep Tumer, Leyla Eminoglu, Fatma Tuba Tags: Erratum Source Type: research

Pulmonary Alveolar Microlithiasis: A novel patient and brief review of the literature
Klin Padiatr DOI: 10.1055/a-1721-2545 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - February 9, 2022 Category: Pediatrics Authors: de Oliveira Mekonnen, Ariana Schwerk, Nicolaus Sch ütz, Katharina Schramm, Leonie Dreissig, Anna Grewendorf, Simon Sukdolak, Cinja Dopfer, Christian Auber, Bernd von Hardenberg, Sandra Happle, Christine Tags: Short Communication Source Type: research

Chronisch krank in der Schule – schulische Fähigkeiten von Kindern mit speziellem Versorgungsbedarf. Ergebnisse der Kindergesundheitsstudie ikidS
Klin Padiatr DOI: 10.1055/a-1672-4709 Hintergrund Die Zusammenhänge zwischen kindlichem Gesundheitsstatus und weiterem Bildungsweg sind unklar. Wir beschreiben die Assoziation zwischen einer chronischen Erkrankung (CE) und schulischen Fähigkeiten am Ende der ersten Klasse. PatientenIm Rahmen der Kindergesundheitsstudie ikidS wurden insgesamt 2003 Schulanfänger der Region Mainz-Bingen rekrutiert. Methode In einer prospektiven Kohortenstudie wurden Kinder mit CE mittels Elternfragebögen über ihren speziellen medizinischen Versorgungsbeda...
Source: Klinische Padiatrie - February 9, 2022 Category: Pediatrics Authors: Schlecht, Jennifer K önig, Jochem Urschitz, Michael S. Tags: Originalarbeit Source Type: research

Differenzierte Sportbefreiung als Chance: Ergebnisse eines Online-Survey und Übersicht über die aktuelle Literatur
Klin Padiatr DOI: 10.1055/a-1721-2755 Hintergrund Die körperliche Aktivität in der Schule trägt relevant zur Bewegungszeit von Schüler*innen bei. Eine differenzierte ärztliche Sportbefreiung (dSB) ermöglicht die angepasste Teilnahme am Sportunterricht im Rahmen der individuellen körperlichen Leistungsfähigkeit. Methode Online-Befragung von Ärzt*innen (2019) und Lehrkräften (zwei Wellen, 2017/19). Neben demographischen Parametern wurden Fragen zur dSB in der Praxis anhand einer 6-Punkt-Likert-Skala erhoben. Mittelwerte wurden mit 95%-K...
Source: Klinische Padiatrie - February 9, 2022 Category: Pediatrics Authors: K önig, Tatjana Tamara Heimann, Alexander Scharenberg, Swantje Kriemler, Susi Muensterer, Oliver Siaplaouras, Jannos Tags: Originalarbeit Source Type: research

Growth and Pubertal Features in a Cohort of 83 Patients with Osteogenesis Imperfecta
Conclusion Reduced growth, significant weight gain over time due to impaired mobility, and high frequency of PP/EP require effective interventions to improve mobility and functional parameters as early as possible in children with OI. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - February 9, 2022 Category: Pediatrics Authors: Öztürk, Ayşe Pınar Dudakl ı, Aslı Özturan, Esin Karakılıç Poyrazo ğlu, Şükran Ba ş, Firdevs Darendeliler, Feyza Tags: Original Article Source Type: research

Two Beer(s) or Not Two Beer(s): The eNose as an Instrument to Pacify the World
Conclusion Our study provides the first objective data of beer flavor. In the long term perspective the eNose might help to overcome the agonizing controversy about beer flavors and, consequently, pacify the World. In the short run, however, our results give support to more targeted and reserved beer consumption during our annual meeting, especially since one specific beer shows a very similar pattern to indoor air. Hintergrund und Fragestellung Sogenannte Stand-up-Abende, Science Slams oder Publikationen wie in der «Christmas-Edition» des "Britis...
Source: Klinische Padiatrie - February 9, 2022 Category: Pediatrics Authors: Kopp, Matthias Volkmar Weckmann, Markus Nissen, Gyde Ricklefs, Isabell H ärtel, Christoph Tags: Original Article Source Type: research

Comorbidities in Children with COVID-19 and MIS-C/PIMS-TS and Risk Factors for Hospitalization, Severe Disease, Intensive Care and Death
Klin Padiatr DOI: 10.1055/a-1727-5895This narrative review sums up data from the SARS-CoV-2-pandemia on preexisting disease/underlying conditions/comorbidities and risk factors in children for severe COVID-19 and MIS-C/PIMS-TS as well as hospitalization and mortality. Young infants and adolescents are at highest risk of hospital and PICU admission. Two or more comorbidities rather than single entities pose a risk for more severe courses of SARS-CoV-2 infection in children. Asthma and malignancy do not increase complication rates. MIS-C/PIMS-TS is not ass...
Source: Klinische Padiatrie - February 3, 2022 Category: Pediatrics Authors: Ankermann, Tobias Brinkmann, Folke Tags: Review Source Type: research

Complete Tracheal Ring Deformity, Recurrent Pneumothoraces and Pleuropulmonary Blastoma in a Child: Coincidence or Common Genetic Cause?
Klin Padiatr DOI: 10.1055/a-1699-2026Complete tracheal ring deformity (CTRD) is a rare abnormality of unknown etiology characterized by circumferentially continuous cartilaginous tracheal rings leading to variable degrees of tracheal stenosis with or without additional heart and lung malformations. Pleuropulmonary blastomas (PPB) are rare malignant mesenchymal tumors, which occur almost exclusively in young children. Pathogenic germline DICER1 variants are associated with PPB but also with other tumors like rhabdomyosarcoma or syndromic diseases like GLOW (Global ...
Source: Klinische Padiatrie - February 3, 2022 Category: Pediatrics Authors: Thiemann, Inga Hoppen, Thomas Laur, Martin Ohlert, Manuel Lobitz, Stephan Schwerk, Nicolaus Dingemann, Jens L änger, Florian Grychtol, Ruth Margarethe N üßlein, Thomas Tags: Pictorial Essay Source Type: research

Myocardial Ischemia in a Preterm Born Baby
Klin Padiatr DOI: 10.1055/a-1723-8353 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - February 3, 2022 Category: Pediatrics Authors: Poryo, Martin Stock, Lilly Ruffing, Sarah Zemlin, Michael Meyer, Sascha Tags: Pictorial Essay Source Type: research

Does Metformin Treatment in Pediatric Population Cause Vitamin B12 Deficiency?
Conclusion Although no significant changes in the serum vitamin B12, homocysteine, MMA or holo-TC-II levels with metformin therapy were detected, long-term prospective studies with high-dose metformin treatment in pediatric population are needed to confirm our results. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - February 3, 2022 Category: Pediatrics Authors: Ta ş, Özen Kontbay, Tugba Dogan, Ozlem Kose, Engin Berberoglu, Merih Siklar, Zeynep Tumer, Leyla Eminoglu, Fatma Tuba Tags: Original Article Source Type: research