Therapiestrategien bei Kindern und Jugendlichen mit Langerhanszell Histiozytosen
Klin Padiatr DOI: 10.1055/a-2146-1395Die derzeitige Standardtherapie bei Kindern und Jugendlichen mit neu diagnostizierter Langerhanszell Histiozytose (LCH) beruht auf den Medikamenten Prednison und Vinblastin. Im Falle eines schlechten Therapieansprechens bzw. Reaktivierung hängt das weitere Vorgehen von Faktoren wie zum Beispiel des Befalls eines Risikoorgans wie Leber, Milz oder hämatopoetisches System ab. Der folgende Artikel gibt eine Übersicht über die wichtigsten aktuellen Daten zu Therapieoptionen in den unterschiedlichen klinischen Situation...
Source: Klinische Padiatrie - September 6, 2023 Category: Pediatrics Authors: Barnbrock, Anke Elisabeth Hutter, Caroline Bochennek, Konrad Minkov, Milen Lehrnbecher, Thomas Tags: Übersicht Source Type: research

The Derivation of Epigastric Motion to Assess Neonatal Breathing and Sleep: An Exploratory Study
Conclusions Standardized motion trackers may detect typical neonatal breathing and body-motion-patterns, that could help to classify neonatal sleep. Respiratory rates can only be determined during quiet sleep. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - September 6, 2023 Category: Pediatrics Authors: Stichtenoth, Guido Knottnerus-Meyer, Niclas Helmstetter, Jonas Maass, Marco Herting, Egbert Tags: Original Article Source Type: research

S1 Guideline: Impairment of gonadal function After Cancer in Childhood and Adolescence
Klin Padiatr DOI: 10.1055/a-2081-0605A possible negative consequence of cancer treatment is the fertility impairment of young cancer survivors. However, most former patients express the wish to have biological children. Fertility-preserving measures are available and are – under certain circumstances – financed by health insurance. Separate information at the time of diagnosis and during follow-up care should be adapted to the individual risk and enable those affected to make a self-determined decision about cryopreservation of germ cells or germ cell ...
Source: Klinische Padiatrie - September 6, 2023 Category: Pediatrics Authors: Borgmann-Staudt, Anja Jantke, Andreas Hinz, Stefan Beckmann, Matthias Dittrich, Ralf Lotz, Laura Balcerek, Magdalena Tags: Diagnostic and Treatment Recommendation Source Type: research

Cardiovascular Screening before Sports Participation: Results of 11487 Children
Conclusion Positive ECG and echocardiography findings involve a very little ratio.But ECG involves an important tool for screening lethal cardiac arrhythmias in asymptomatic patients.If ECG or echocardiography couldn’t be taken, further evaluation should be necessary with symptoms and/or family history. Keywords: Echocardiography, electrocardiography, pediatric, screening, sports [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - September 4, 2023 Category: Pediatrics Authors: Duman, Derya Demetg ül, Hasan Sel, Kutay D önmez, Yasemin Nuran Çelikkaya, Mehmet Emin H üzmeli, Esra Doğru Ak ın, Alper Tags: Original Article Source Type: research

Aktualisierte AWMF Leitlinie zur Diagnostik und Therapie der Langerhanszell Histiozytose (LCH) im Kindes- und Jugendalter
Klin Padiatr DOI: 10.1055/a-2135-3175Die Langerhanszell Histiozytose (LCH) ist eine seltene neoplastische Erkrankung, die vor allem im Kindes- und Jugendalter auftritt. Die Erkrankung kann prinzipiell jedes Organ befallen, weswegen sehr unterschiedliche klinische Erscheinungsbilder möglich sind. Der klinische Verlauf der LCH reicht von einer Spontanheilung bis hin zu einem rasch progredienten tödlichen Verlauf. Die Ausbreitungsdiagnostik bestimmt das Vorgehen. Manche Patienten qualifizieren sich für eine watch-and-wait Strategie, während andere einer...
Source: Klinische Padiatrie - September 4, 2023 Category: Pediatrics Authors: Lehrnbecher, Thomas Ahlmann, Martina Albert, Michael Barnbrock, Anke Elisabeth Beutel, Karin Bochennek, Konrad Classen, Carl Friedrich Holzhauer, Susanne Hutter, Caroline Lakatos, Karoly Meisel, Roland Porto, Luciana Vokuhl, Christian Vraetz, Thomas Minko Tags: Diagnostic and Treatment Recommendation Source Type: research

Comparison of Transcutaneous and Total Serum Bilirubin Measurements at Five Different Sites in Newborns before and after Phototherapy
Conclusions TcB levels were most accurately measured at the interscapular site and covered hipbone before and immediately after phototherapy, respectively. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - August 30, 2023 Category: Pediatrics Authors: Eken, Seda Ilhan, Ozkan Hakan, Nilay Tags: Original Article Source Type: research

Chronic Hepatitis B In Children: Case Series From A Tertiary Paediatric Hospital
Conclusion HBV infection and CHB continue to be an important problem for children in our country. Consensus on the appropriate ALT ULN is needed for the treatment of hepatitis in children. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - August 28, 2023 Category: Pediatrics Authors: Zirek, Fazilcan Hosnut, Ferda Ozbay Sahin, Gulseren Senel, Saliha Tags: Original Article Source Type: research

Bilateral Anotia In A Preterm Neonate After Maternal Retinoic Acid Exposure
Klin Padiatr DOI: 10.1055/a-2057-0379 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - July 28, 2023 Category: Pediatrics Authors: Zeybek, Cengiz Karagol, Belma Saygili Tags: Pictorial Essay Source Type: research

Cornelia de Lange Syndrome Presenting as Hydrops Fetalis due to Intestinal Atresia
Klin Padiatr DOI: 10.1055/a-2099-3386 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - July 21, 2023 Category: Pediatrics Authors: Yildiz, Duran Cakir, Ufuk Kahvecioglu, Dilek Alan, Serdar Erdeve, Omer Atasay, Begum Arsan, Saadet Tags: Short Communication Source Type: research

Bridging the gap: A quality improvement project to implement psychosocial care standards into clinical practice in pediatric oncology
Discussion The iterative development of the “My Logbook” including local and international experts as well as the patient and practical perspective allow for the design of a process-oriented, consensus – and evidence-based tool directly translating the S3-Guideline into clinical practice. Feasibility and applicability are fostered through an iterative process of constant evaluation and adaptation of the tool by international experts and through the clinical experience gathered in the multi-centered pilot study. Furthermore, the systematic evaluatio...
Source: Klinische Padiatrie - July 21, 2023 Category: Pediatrics Authors: Weiler-Wichtl, Liesa J. Fohn-Erhold, Verena Schneider, Carina Schwarzinger, Agathe Krottendorfer, Kerstin Pletschko, Thomas Rosenmayr, Verena Gojo, Johannes Peyrl, Andreas Dieckmann, Karin Kollmann, Alina Stefanie Hansl, Rita Slavc, Irene Fries, Jonathan Tags: Review Source Type: research

Massive Air Leak Syndrome During High Flow Oxygen Therapy and a Rare Complication: Pneumorrhachis
Klin Padiatr DOI: 10.1055/a-2041-2914 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - July 11, 2023 Category: Pediatrics Authors: G öktuğ, Aytaç S önmez, Songül Eren, Din çel Çağlar, Özgür Yildiz, Yasemin Tasci Yazici, Mutlu Uysal Tuygun, Nilden Tags: Short Communication Source Type: research

Progression and Relapse of Pediatric Soft Tissue Sarcoma: Individualized Approach of Treatment – Experience from a Major Pediatric Cancer Center in Europe
Conclusion In addition to well characterized clinical factors such as local or systemic relapse, the Oberlin score could be helpful in counselling patients and their families for choosing the best strategy of care. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - July 11, 2023 Category: Pediatrics Authors: Barnbrock, Anke Elisabeth Luckowitsch, Marie Schmidt, Stanislaw Buus-Gehrig, Constanze Koscher, Leila Becker, Martina Vokuhl, Christian Klingebiel, Thomas Lehrnbecher, Thomas Bochennek, Konrad Tags: Original Article Source Type: research

COVID-19 Induced Hemophagocytic Lymphohistiocytosis in a Patient with Novel Homozygous UNC13D Gene Variant
Klin Padiatr 2023; 235: 258-260 DOI: 10.1055/a-2081-0522 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - July 7, 2023 Category: Pediatrics Authors: Tekeli, Seher Erman, Baran Kurucu, Burcak Tanir, Gonul Aytekin, Caner Tags: Short Communication Source Type: research

Involuntary Movements in Cobalamin Deficiency
Conclusion Recognition of nutritional cobalamin deficiency is important to perform a differential diagnosis of the condition from seizures or other causes of involuntary movements and avoid aggressive therapy and over treatment. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - June 28, 2023 Category: Pediatrics Authors: Özyürek, Hamit Ince, Hulya Tasdemir, Haydar Ali Aydin, Omer Faruk Tags: Original Article Source Type: research

Erratum: Erh öhte epigenitische Alterung in Nasenepithelzellen von symptomatischen Asthmatikern im Vergleich zu Gesunden
Klin Padiatr 2023; 235: e16-e16 DOI: 10.1055/a-2109-9390 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Klinische Padiatrie)
Source: Klinische Padiatrie - June 27, 2023 Category: Pediatrics Authors: Buchholz, Sonja K ünstner, Axel Bahmer, Thomas Hansen, Gesine von Mutius, Erika Rabe, Klaus F. Dittrich, Anna-Maria Schaub, Bianca Happle, Christine Kopp, Matthias V. Busch, Hauke Weckmann, Markus Tags: Erratum Source Type: research