Patient-led data sharing for clinical bioinformatics research: USCDI and beyond
AbstractThe 21st Century Cures Act, passed in 2016, and the Final Rules it called for create a roadmap for enabling patient access to their electronic health information. The set of data to be made available, as determined by the Office of the National Coordinator for Health IT through the US Core Data for Interoperability expansion process, will impact the value creation of this improved data liquidity. In this commentary, we look at the potential for significant value creation from USCDI in the context of clinical bioinformatics research and advocate for the research community ’s involvement in the USCDI process to pro...
Source: Journal of the American Medical Informatics Association - July 19, 2021 Category: Information Technology Source Type: research

A novel application of SMART on FHIR architecture for interoperable and scalable integration of patient-reported outcome data with electronic health records
ConclusionOur approach and solution proved feasible, secure, and time- and resource-efficient. We offer actionable guidance for this technology to be scaled and adapted to promote adoption in diverse ambulatory care settings and across different EHRs. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 19, 2021 Category: Information Technology Source Type: research

Are synthetic clinical notes useful for real natural language processing tasks: A case study on clinical entity recognition
Conclusions: Recent advances in text generation have made it possible to generate synthetic clinical notes that could be useful for training NER models for information extraction from natural clinical notes, thus lowering the privacy concern and increasing data availability. Further investigation is needed to apply this technology to practice. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 17, 2021 Category: Information Technology Source Type: research

Utilizing timestamps of longitudinal electronic health record data to classify clinical deterioration events
ConclusionThis study demonstrates that our recurrent neural network models using only timestamps of longitudinal electronic health record data that reflect healthcare processes achieve well-performing discriminative power. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 16, 2021 Category: Information Technology Source Type: research

DeepADEMiner: a deep learning pharmacovigilance pipeline for extraction and normalization of adverse drug event mentions on Twitter
ConclusionMining ADEs from Twitter posts using a pipeline architecture requires the different components to be trained and tuned based on input data imbalance in order to ensure optimal performance on the end-to-end resolution task. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 16, 2021 Category: Information Technology Source Type: research

Integrated digital pathology at scale: A solution for clinical diagnostics and cancer research at a large academic medical center
ConclusionsWe highlight major challenges and lessons learned when going digital to provide orientation for other pathologists. Building interconnected solutions will not only increase adoption of DP, but also facilitate next-generation computational pathology at scale for enhanced cancer research. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 14, 2021 Category: Information Technology Source Type: research

Digital Disparities: Lessons learned from a Patient Reported Outcomes Program During the COVID-19 Pandemic
AbstractThe collection of patient reported outcomes (PROs) allows us to incorporate the patient ’s voice within their care in a quantifiable, validated manner. Large scale collection of PROs is facilitated by the electronic health record (EHR) and its portal, though historically patients have eschewed the portal and completed patient reported outcome measures (PROMS) in clinic via tablet. Fu rthermore, access to and use of the portal is associated with known racial inequities. Our institution oversees the largest clinical PRO program in the world, and has a long history of racially equitable PRO completion rates via tabl...
Source: Journal of the American Medical Informatics Association - July 9, 2021 Category: Information Technology Source Type: research

Replication studies in the clinical decision support literature –frequency, fidelity, and impact
ConclusionThere is an urgent need to better characterize which core CDSS principles require replication, identify past replication data, and conduct missing replication studies. Attention to replication should improve the efficiency and effectiveness of CDSS research and avoiding potentially harmful trial and error technology deployment. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 6, 2021 Category: Information Technology Source Type: research

A decade post-HITECH: Critical access hospitals have electronic health records but struggle to keep up with other advanced functions
ConclusionsThe advanced use divide prevents CAH patients from benefitting from a fully digitized healthcare system. To close the widening gap in CDA, policymakers should consider partnering with vendors to develop implementation guides and standards for functions like dashboards and high-risk patient identification algorithms to better support CAH adoption. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 1, 2021 Category: Information Technology Source Type: research

Interpretable disease prediction using heterogeneous patient records with self-attentive fusion encoder
ConclusionWe suggest an interpretable disease prediction model that efficiently fuses heterogeneous patient records and demonstrates superior disease prediction performance. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 1, 2021 Category: Information Technology Source Type: research

Aggregating large-scale databases for PubMed author name disambiguation
ConclusionsThe feasibility and good performance of our methods not only help better understand the importance of external databases for disambiguation, but also point to a promising direction for future AND studies in which information aggregated from multiple bibliographic databases can be effective in improving disambiguation performance. The methodology shown here can be generalized to broader bibliographic databases beyond PubMed. Our code and data are available online (https://github.com/carmanzhang/PubMed-AND-method). (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 28, 2021 Category: Information Technology Source Type: research

Sticky apps, not sticky hands: A systematic review and content synthesis of hand hygiene mobile apps
ConclusionsAlthough many hand hygiene apps exist, few provide content on best practice. Many did not meet the minimum acceptability criterion for quality or were formally trialed or tested. Research should assess the feasibility and effectiveness of hand hygiene apps (especially within healthcare settings), including when and how they “work.” We recommend that future apps to support hand hygiene practice are developed with infection prevention and control experts and align with best practice. Robust research is needed to determine which innovative methods of engagement create “sticky” apps. (Source: Journal of the ...
Source: Journal of the American Medical Informatics Association - June 28, 2021 Category: Information Technology Source Type: research

Comparison of women and men in biomedical informatics scientific dissemination: retrospective observational case study of the AMIA Annual Symposium: 2017 –2020
ConclusionWe found little evidence of major bias against women in submission, acceptance, and awards associated with the AMIA Annual Symposium from 2017 to 2020. Our study is unique because of the analysis of both authors and reviewers. The encouraging findings raise awareness of progress and remaining opportunities in biomedical informatics scientific dissemination. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 28, 2021 Category: Information Technology Source Type: research

Impact of the 2015 Health Information Technology Certification Edition on Interoperability among Hospitals
ConclusionsCertified technology is one mechanism to ensure providers use recent and safe technologies for interoperable exchange. Adoption of certified EHRs improves the nation ’s interoperable exchange; however, it has a clear limited effect. Other mechanisms are necessary for achieving comprehensive interoperable exchange. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 28, 2021 Category: Information Technology Source Type: research

Biomedical and clinical English model packages for the Stanza Python NLP library
ConclusionsWe introduce biomedical and clinical NLP packages built for the Stanza library. These packages offer performance that is similar to the state of the art, and are also optimized for ease of use. To facilitate research, we make all our models publicly available. We also provide an online demonstration (http://stanza.run/bio). (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 22, 2021 Category: Information Technology Source Type: research