Smashing the strict hierarchy: three cases of clinical decision support malfunctions involving carvedilol
AbstractClinical vocabularies allow for standard representation of clinical concepts, and can also contain knowledge structures, such as hierarchy, that facilitate the creation of maintainable and accurate clinical decision support (CDS). A key architectural feature of clinical hierarchies is how they handle parent-child relationships — specifically whether hierarchies are strict hierarchies (allowing a single parent per concept) or polyhierarchies (allowing multiple parents per concept). These structures handle subsumption relationships (ie, ancestor and descendant relationships) differently. In this paper, we descr...
Source: Journal of the American Medical Informatics Association - July 26, 2018 Category: Information Technology Source Type: research

The 21st Century Cures Act and electronic health records one year later: will patients see the benefits?
AbstractWhile federal regulation provides patients the right to access their electronic health records and promotes increased use of health information technology, patient access to electronic health records remains limited. The 21st Century Cures Act, signed into law over a year ago, has important provisions that could significantly improve access and availability of health data. Specifically, the provisions call for partnerships among health information exchange networks, educational and research initiatives, and health information technology certification requirements that encourage interoperability. The article reviews...
Source: Journal of the American Medical Informatics Association - July 26, 2018 Category: Information Technology Source Type: research

Online peer support groups for family caregivers: are they reaching the caregivers with the greatest needs?
ConclusionsWe show that family caregivers with the most caregiving demands are most engaged with online support communities. This suggests that online communities could be used to support the most vulnerable family caregivers. The implications of this work for online support systems are discussed. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 16, 2018 Category: Information Technology Source Type: research

Rejoinder to “Ethical issues in the use of SMS messaging in HIV care and treatment in low-and-middle-income countries”
Dear Madam, (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 12, 2018 Category: Information Technology Source Type: research

Learning predictive models of drug side-effect relationships from distributed representations of literature-derived semantic predications
ConclusionOur methods can assist the pharmacovigilance process using information from the biomedical literature. Unsupervised pretraining generates a rich relationship-based representational foundation for machine learning techniques to classify drugs in the context of a putative side effect, given known examples. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 11, 2018 Category: Information Technology Source Type: research

Conversational agents in healthcare: a systematic review
ConclusionsThe use of conversational agents with unconstrained natural language input capabilities for health-related purposes is an emerging field of research, where the few published studies were mainly quasi-experimental, and rarely evaluated efficacy or safety. Future studies would benefit from more robust experimental designs and standardized reporting.Protocol RegistrationThe protocol for this systematic review is registered at PROSPERO with the number CRD42017065917. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 11, 2018 Category: Information Technology Source Type: research

Gaps in health information exchange between hospitals that treat many shared patients
ConclusionsDespite increased HIE engagement, our descriptive results indicate that HIE is not developing in a way that facilitates information exchange where it might benefit the most patients. New policy efforts, particularly those emerging from the 21st Century Cures Act, need to explicitly pursue strategies that ensure that HSP providers engage in exchange with each other. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 11, 2018 Category: Information Technology Source Type: research

Research use of electronic health records: patients ’ perspectives on contact by researchers
The objective of this study was to explore patients ’ attitudes and opinions about potential contact by researchers who have had access to their EHRs.Materials and methodsWe conducted 15 focus groups in four diverse counties in the southeastern United States. We designed vignettes to describe different situations in which researchers conducting a hypothetical study might have reason to consider contact with patients.ResultsMany patients believed it was important for researchers to take action if they discovered information suggesting a current serious health concern. Relaying the information through patients ’ ...
Source: Journal of the American Medical Informatics Association - July 6, 2018 Category: Information Technology Source Type: research

Assessing the impact of health system organizational structure on hospital electronic data sharing
ConclusionPolicymakers should be wary of claims that horizontal consolidation will lead to interoperability gains. Future research should explore the specific mechanisms that lead to greater interoperability in certain health system organizational structures. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 4, 2018 Category: Information Technology Source Type: research

Clinical decision support directed to primary care patients and providers reduces cardiovascular risk: a randomized trial
AbstractObjectiveTo test the hypothesis that use of a clinical decision support (CDS) system in a primary care setting can reduce cardiovascular (CV) risk in patients.Materials and MethodsTwenty primary care clinics were randomly assigned to usual care (UC) or CDS. For CDS clinic patients identified algorithmically with high CV risk, rooming staff were prompted by the electronic health record (EHR) to print CDS that identified evidence-based treatment options for lipid, blood pressure, weight, tobacco, or aspirin management and prioritized them based on potential benefit to the patient. The intention-to-treat analysis incl...
Source: Journal of the American Medical Informatics Association - July 3, 2018 Category: Information Technology Source Type: research

A systematic assessment of the availability and clinical drug information coverage of machine-readable clinical drug data sources for building knowledge translation products
ConclusionOur study demonstrated the availability of machine-readable clinical drug data that could help facilitate the creation of novel drug knowledge translation products. However, we identified clinical content gaps in the available non-proprietary drug information sources. Further evaluation of the quality of each data source would be necessary prior to incorporating these sources into any knowledge translation products intended for clinical use. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 3, 2018 Category: Information Technology Source Type: research

Effectiveness of provider price display in computerized physician order entry (CPOE) on healthcare quality: a systematic review
ConclusionsPublished evidence suggests that price display tools aimed at ordering providers in EHR/CPOE do not influence the efficiency domain of healthcare quality. Scant published evidence suggests that they do not influence the effectiveness and patient safety domains of healthcare quality. Future studies are needed to assess the relationship between provider price display and unexplored domains of healthcare quality (patient centered, equitable, and timely care).RegistrationPROSPERO registration: CRD42018082227 (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 3, 2018 Category: Information Technology Source Type: research

A usability and safety analysis of electronic health records: a multi-center study
AbstractTo characterize the variability in usability and safety of EHRs from two vendors across four healthcare systems (2 Epic and 2 Cerner). Twelve to 15 emergency medicine physicians participated from each site and completed six clinical scenarios. Keystroke, mouse click, and video data were collected. From the six scenarios, two diagnostic imaging, laboratory, and medication tasks were analyzed. There was wide variability in task completion time, clicks, and error rates. For certain tasks, there were an average of a nine-fold difference in time and eight-fold difference in clicks. Error rates varied by task (X-ray 16.7...
Source: Journal of the American Medical Informatics Association - July 2, 2018 Category: Information Technology Source Type: research

OpenNotes and shared decision making: a growing practice in clinical transparency and how it can support patient-centered care
ConclusionOur study showed evidence of a relationship between note reading and perceived SDM. Implementation of SDM is likely to expand, given its association with improved patient satisfaction, adherence, and medical decision making. Findings from this study highlight OpenNotes as a policy that institutions can implement as a facilitator of SDM and a manifestation of their commitment to patient autonomy and transparency. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 29, 2018 Category: Information Technology Source Type: research

Using wearable technology to predict health outcomes: a literature review
ConclusionWearable technology has significant potential to assist in predicting clinical outcomes, but needs further study. Well-designed clinical trials that incorporate data from wearable technology into clinical outcome prediction models are required to realize the opportunities of this advancing technology. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 29, 2018 Category: Information Technology Source Type: research

Identifying surgical site infections in electronic health data using predictive models
ConclusionsEHR data can facilitate SSI surveillance with adequate sensitivity and PPV. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 29, 2018 Category: Information Technology Source Type: research

Reining in the QTc: reducing the risk of Torsades de Pointes across a major health system
AbstractHospitalized patients have a high prevalence of prolonged QTc and are a high-risk population for Torsades de Pointes (TdP). One modifiable risk factor for TdP is the use of QT prolonging drugs. Electronically alerting providers who are ordering QT prolonging drugs in at-risk patients may help to achieve safer prescribing practices. Our previous study decreased inappropriate prescription of IV haloperidol by 36% using a targeted “smart” electronic alert. We wanted to assess an approach to expanding this type of electronic alert to commonly used QT prolonging medications and evaluate how this would affect...
Source: Journal of the American Medical Informatics Association - June 28, 2018 Category: Information Technology Source Type: research

Unstructured clinical documentation reflecting cognitive and behavioral dysfunction: toward an EHR-based phenotype for cognitive impairment
This study examined unstructured data on symptoms of CI in the acute-care EHRs of hip and stroke fracture patients with dementia from two hospitals. Clinician reviewers identified and classified unstructured EHR data using standardize d criteria. Relevant narrative text was descriptively characterized and evaluated for key terminology. Most patient EHRs (90%) had narrative text reflecting cognitive and/or behavioral dysfunction common in CI that were reliably classified (κ 0.82). The majority of statements reflected vague descri ptions of cognitive/behavioral dysfunction as opposed to diagnostic terminology. Findings...
Source: Journal of the American Medical Informatics Association - June 27, 2018 Category: Information Technology Source Type: research

The national cost of adverse drug events resulting from inappropriate medication-related alert overrides in the United States
ConclusionThese data suggest that further optimization of hospitals computerized provider order entry systems and their associated clinical decision support is needed and would result in substantial savings. We have erred on the side of caution in developing this range, taking two conservative cost estimates for a preventable ADE that did not include malpractice or litigation costs, or costs of injuries to patients. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 22, 2018 Category: Information Technology Source Type: research

Corrigendum to: A snapshot of health information exchange across five nations: an investigation of frontline clinician experiences in emergency care
Klapman S, Sher Em, Adler-Milstein J. A snapshot of health information exchange across five nations: an investigation of frontline clinician experiences in emergency care. J Am Med Inform Assoc 2018; 25(6):686-93. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 21, 2018 Category: Information Technology Source Type: research

A visual analytics approach for pattern-recognition in patient-generated data
ConclusionsVisual analytics have the potential to mitigate provider concerns about the volume of self-monitoring data. Glucolyzer helped dietitians identify meaningful patterns in self-monitoring data without incurring perceived information overload. Future studies should assess whether similar tools can support clinicians in personalizing behavioral interventions that improve patient outcomes. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 13, 2018 Category: Information Technology Source Type: research

Opportunities and challenges in developing deep learning models using electronic health records data: a systematic review
DiscussionDespite the early success in using deep learning for health analytics applications, there still exist a number of issues to be addressed. We discuss them in detail including data and label availability, the interpretability and transparency of the model, and ease of deployment. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 8, 2018 Category: Information Technology Source Type: research

Development and implementation of a mobile device-based pediatric electronic decision support tool as part of a national practice standardization project
ConclusionsECDS tools may prove valuable in future national practice standardization initiatives. Work should next focus on developing robust analytics to determine ECDS tools ’ impact on medical decision making, clinical practice, and health outcomes. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 7, 2018 Category: Information Technology Source Type: research

Using mobile location data in biomedical research while preserving privacy
AbstractLocation data are becoming easier to obtain and are now bundled with other metadata in a variety of biomedical research applications. At the same time, the level of sophistication required to protect patient privacy is also increasing. In this article, we provide guidance for institutional review boards (IRBs) to make informed decisions about privacy protections in protocols involving location data. We provide an overview of some of the major categories of technical algorithms and medical –legal tools at the disposal of investigators, as well as the shortcomings of each. Although there is no “one size f...
Source: Journal of the American Medical Informatics Association - June 7, 2018 Category: Information Technology Source Type: research

Trends in user ratings and reviews of a popular yet inaccurate blood pressure-measuring smartphone app
DiscussionUser reviews and ratings of a popular, inaccurate BP-measuring app were positive and uncommonly commented on its inaccuracy. Disclaimers attempting to prevent medical use of the app were ineffective. These findings support the need for more rigorous regulatory review of apps prior to their release. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 7, 2018 Category: Information Technology Source Type: research

The National Sleep Research Resource: towards a sleep data commons
ConclusionsThe NSRR offers a use case and an example for creating a full-fledged data commons. It provides a single point of access to analysis-ready physiological signals from polysomnography obtained from multiple sources, and a wide variety of clinical data to facilitate sleep research. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 31, 2018 Category: Information Technology Source Type: research

Empowering genomic medicine by establishing critical sequencing result data flows: the eMERGE example
AbstractThe eMERGE Network is establishing methods for electronic transmittal of patient genetic test results from laboratories to healthcare providers across organizational boundaries. We surveyed the capabilities and needs of different network participants, established a common transfer format, and implemented transfer mechanisms based on this format. The interfaces we created are examples of the connectivity that must be instantiated before electronic genetic and genomic clinical decision support can be effectively built at the point of care. This work serves as a case example for both standards bodies and other organiz...
Source: Journal of the American Medical Informatics Association - May 31, 2018 Category: Information Technology Source Type: research

Hospitals ’ adoption of intra-system information exchange is negatively associated with inter-system information exchange
ConclusionConsistent with the U.S. goals for more widely accessible patient information, hospitals ’ ability to share information has increased over time. However, hospitals are prioritizing within-organizational information exchange over exchange between different organizations. If increasing inter-system exchanges is a desired goal, current market incentives and government policies may be ins ufficient to overcome hospitals’ motivations for pursuing an intra-system-information-exchange-first strategy. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 30, 2018 Category: Information Technology Source Type: research

The LOINC RSNA radiology playbook - a unified terminology for radiology procedures
ConclusionsThe LOINC/RSNA Radiology Playbook provides a universal terminology standard for radiology orders and results. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 29, 2018 Category: Information Technology Source Type: research

Corrigendum to: Journal of the American Medical Informatics Association, Volume 23, Issue 1, 1 January 2016, Pages 230 –239, https://doi.org/10.1093/jamia/ocv100
In Charlier et al 2016, Serious games for improving knowledge and self-management in young people with chronic conditions: a systematic review and meta-analysis.Journal of the American Medical Informatics Association, Volume 23, Issue 1, 1 January 2016, Pages 230 –239, some small errors in the sample sizes occurred inFigure  2 and3. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 29, 2018 Category: Information Technology Source Type: research

Evaluating utility and compliance in a patient-based eHealth study using continuous-time heart rate and activity trackers
AbstractTelemedicine has been used to remotely diagnose and treat patients, yet previously applied telemonitoring approaches have been fraught with adherence issues. The primary goal of this study was to evaluate the adherence rates using a consumer-grade continuous-time heart rate and activity tracker in a mid-risk cardiovascular patient population. As a secondary analysis, we show the ability to utilize the information provided by this device to identify information about a patient ’s state by correlating tracker information with patient-reported outcome survey scores. We showed that using continuous-time activity ...
Source: Journal of the American Medical Informatics Association - May 29, 2018 Category: Information Technology Source Type: research

Response to Rejoinder to “Ethical issue in the use of SMS messaging in HIV care and treatment in low- and middle-income countries: case examples from Mozambique”
To the editor: (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 29, 2018 Category: Information Technology Source Type: research

Erratum to: Clinical pathways for primary care: current use, interest and perceived usability
In the article “Clinical pathways for primary care: current use, interest and perceived usability,” the author order was listed incorrectly and has been amended. We apologize for the error. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 25, 2018 Category: Information Technology Source Type: research

Using drug knowledgebase information to distinguish between look-alike-sound-alike drugs
ConclusionsDrug indications data from a drug knowledgebase can discriminate between many LASA drugs. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 22, 2018 Category: Information Technology Source Type: research

A telehealth system for automated diagnosis of asthma and chronical obstructive pulmonary disease
AbstractThis paper presents the development and real-time testing of an automated expert diagnostic telehealth system for the diagnosis of 2 respiratory diseases, asthma and Chronic Obstructive Pulmonary Disease (COPD). The system utilizes Android, Java, MATLAB, and PHP technologies and consists of a spirometer, mobile application, and expert diagnostic system. To evaluate the effectiveness of the system, a prospective study was carried out in 3 remote primary healthcare institutions, and one hospital in Bosnia and Herzegovina healthcare system. During 6 months, 780 patients were assessed and diagnosed with an accuracy of ...
Source: Journal of the American Medical Informatics Association - May 18, 2018 Category: Information Technology Source Type: research

PheProb: probabilistic phenotyping using diagnosis codes to improve power for genetic association studies
ConclusionsPheProb improves statistical power for association studies relative to standard thresholding approaches by leveraging information about the phenotype in the billing code counts. The PheProb approach has direct applications where efficient approaches are required, such as in Phenome-Wide Association Studies. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 17, 2018 Category: Information Technology Source Type: research

Rethinking the outpatient medication list: increasing patient activation and education while architecting for centralization and improved medication reconciliation
ConclusionsPatient and caregiver participation are essential to improve medication safety. Our medication manager is an early step towards a patient-facing medication manager that has been designed with data federation and interoperability in mind. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 17, 2018 Category: Information Technology Source Type: research

Psychometric evaluation of the Smartphone for Clinical Work Scale to measure nurses ’ use of smartphones for work purposes
ConclusionsThe 15-item SCWS showed satisfactory psychometric properties for use in future studies. These studies can focus on identifying factors associated with nurses ’ use of smartphones for work purposes. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 17, 2018 Category: Information Technology Source Type: research

Variability in adolescent portal privacy features: how the unique privacy needs of the adolescent patient create a complex decision-making process
ConclusionsIn the absence of universally accepted standards, medical organizations typically undergo an arduous decision-making process to develop teen portal policies, weighing legal, economic, social, clinical, and technological factors. As a result, portal access policies are highly inconsistent across the United States and within individual states. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 17, 2018 Category: Information Technology Source Type: research

Good intentions are not enough: how informatics interventions can worsen inequality
AbstractHealth informatics interventions are designed to help people avoid, recover from, or cope with disease and disability, or to improve the quality and safety of healthcare. Unfortunately, they pose a risk of producing intervention-generated inequalities (IGI) by disproportionately benefiting more advantaged people. In this perspective paper, we discuss characteristics of health-related interventions known to produce IGI, explain why health informatics interventions are particularly vulnerable to this phenomenon, and describe safeguards that can be implemented to improve health equity. We provide examples in which hea...
Source: Journal of the American Medical Informatics Association - May 16, 2018 Category: Information Technology Source Type: research

Criteria for assessing the quality of mHealth apps: a systematic review
ConclusionsThere is a wide heterogeneity in assessment criteria for mHealth apps. It is necessary to define the exact meanings and degree of distinctness of each criterion. This will help to improve the existing tools and may lead to achieve a better comprehensive mHealth app assessment tool. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 16, 2018 Category: Information Technology Source Type: research

Provider and patient satisfaction with the integration of ambulatory and hospital EHR systems
ConclusionsDissatisfaction of providers with an EHR system and difficulties incorporating EHR technology into patient care may negatively impact patient satisfaction. Care must be taken during EHR implementations to maintain good communication with patients while satisfying documentation requirements. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 16, 2018 Category: Information Technology Source Type: research

Presenting self-monitoring test results for consumers: the effects of graphical formats and age
AbstractObjectiveTo examine the effects of graphical formats and age on consumers ’ comprehension and perceptions of the use of self-monitoring test results.MethodsParticipants (36 older and 36 young adults) were required to perform verbatim comprehension and value interpretation tasks with hypothetical self-monitoring test results. The test results were randomly presented by four reference range number lines: basic, color enhanced, color/text enhanced, and personalized information enhanced formats. We measured participants ’ task performance and eye movement data during task completion, and their perceptions a...
Source: Journal of the American Medical Informatics Association - May 11, 2018 Category: Information Technology Source Type: research

Using statistical anomaly detection models to find clinical decision support malfunctions
ConclusionsMalfunctions/anomalies occur frequently in CDS alert systems. It is important to be able to detect such anomalies promptly. Anomaly detection models are useful tools to aid such detections. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 11, 2018 Category: Information Technology Source Type: research

Machine learning approach for early detection of autism by combining questionnaire and home video screening
ConclusionThese findings suggest that a mobile, machine learning process is a reliable method for detection of autism outside of clinical settings. A variety of confounding factors in the clinical analysis are discussed along with the solutions engineered into the algorithms. Final results are statistically limited and will benefit from future clinical studies to extend the sample size. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 7, 2018 Category: Information Technology Source Type: research

Technology use and preferences to support clinical practice guideline awareness and adherence in individuals with sickle cell disease
ConclusionsThis study ’s findings can inform the design of clinical practice guideline applications, suggesting a promising role for technology to engage patients, facilitate care decisions and actions, and improve outcomes. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 7, 2018 Category: Information Technology Source Type: research

Monitoring for change: the role of family and friends in helping older adults manage personal health information
ConclusionsFF frequently monitor for change in OA well-being, seeking up-to-date information to facilitate support of OA PHIM. Health information technology tools designed for FF can support all phases of monitoring by providing: (1) timely and granular levels of access to OA health information as the OA ages; (2) tailored health education for FF that is based on OA clinical data; and (3) networking platforms that integrate delegation, volunteering, and relevant resources, along with tools to facilitate support of OA appointment calendars and medication management. Such tools could reduce the burden of PHIM for OA and thei...
Source: Journal of the American Medical Informatics Association - May 2, 2018 Category: Information Technology Source Type: research

The benefits of health information exchange: an updated systematic review
ConclusionsThe current systematic review found that studies with more rigorous designs all reported benefits from HIE. Such benefits include fewer duplicated procedures, reduced imaging, lower costs, and improved patient safety. We also found that studies evaluating community HIEs were more likely to find benefits than studies that evaluated enterprise HIEs or vendor-mediated exchanges. Overall, these finding bode well for the HIEs ability to deliver on anticipated improvements in care delivery and reduction in costs. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - April 28, 2018 Category: Information Technology Source Type: research

Automatic recognition of self-acknowledged limitations in clinical research literature
ConclusionsThe approach presented can be incorporated into the workflows of stakeholders focusing on research transparency to improve reporting of limitations in clinical studies. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - April 28, 2018 Category: Information Technology Source Type: research

Design and implementation of a standardized framework to generate and evaluate patient-level prediction models using observational healthcare data
ConclusionsThe proof-of-concept study illustrates the framework ’s ability to develop reproducible models that can be readily shared and offers the potential to perform extensive external validation of models, and improve their likelihood of clinical uptake. In future work the framework will be applied to perform an “all-by-all” prediction analysis to asse ss the observational data prediction domain across numerous target populations, outcomes and time, and risk settings. (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - April 27, 2018 Category: Information Technology Source Type: research