Patient-level temporal aggregation for text-based asthma status ascertainment.
CONCLUSION: Results contrasted the strengths of several aggregation algorithms in different settings. Multiple approaches exhibited good patient classification performance, and also predicted the timing of estimates with reasonable accuracy. PMID: 24833775 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 15, 2014 Category: Information Technology Authors: Wu ST, Juhn YJ, Sohn S, Liu H Tags: J Am Med Inform Assoc Source Type: research

Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS): Architecture.
We describe the architecture of the Patient Centered Outcomes Research Institute (PCORI) funded Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS, http://www.SCILHS.org) clinical data research network, which leverages the $48 billion dollar federal investment in health information technology (IT) to enable a queryable semantic data model across 10 health systems covering more than 8 million patients, plugging universally into the point of care, generating evidence and discovery, and thereby enabling clinician and patient participation in research during the patient encounter. Central to the suc...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Mandl KD, Kohane IS, McFadden D, Weber GM, Natter M, Mandel J, Schneeweiss S, Weiler S, Klann JG, Bickel J, Adams WG, Ge Y, Zhou X, Perkins J, Marsolo K, Bernstam E, Showalter J, Quarshie A, Ofili E, Hripcsak G, Murphy SN Tags: J Am Med Inform Assoc Source Type: research

Louisiana Clinical Data Research Network: establishing an infrastructure for efficient conduct of clinical research.
Abstract The state of Louisiana, like the nation as a whole, is facing the salient challenge of improving population health and efficiency of healthcare delivery. Research to inform innovations in healthcare will best enhance this effort if it is timely, efficient, and patient-centered. The Louisiana Clinical Data Research Network (LACDRN) will increase the capacity to conduct robust comparative effectiveness research by building a health information technology infrastructure that provides access to comprehensive clinical data for more than 1 million patients statewide. To ensure that network-based research best s...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Khurshid A, Nauman E, Carton T, Horswell R Tags: J Am Med Inform Assoc Source Type: research

CAPriCORN: Chicago Area Patient-Centered Outcomes Research Network.
ltzer DO, Collins JM, Mazany T, for the CAPriCORN Team Abstract The Chicago Area Patient-Centered Outcomes Research Network (CAPriCORN) represents an unprecedented collaboration across diverse healthcare institutions including private, county, and state hospitals and health systems, a consortium of Federally Qualified Health Centers, and two Department of Veterans Affairs hospitals. CAPriCORN builds on the strengths of our institutions to develop a cross-cutting infrastructure for sustainable and patient-centered comparative effectiveness research in Chicago. Unique aspects include collaboration with the Universit...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Kho AN, Hynes DM, Goel S, Solomonides AE, Price R, Hota B, Sims SA, Bahroos N, Angulo F, Trick WE, Tarlov E, Rachman FD, Hamilton A, Kaleba EO, Badlani S, Volchenboum SL, Silverstein JC, Tobin JN, Schwartz MA, Levine D, Wong JB, Kennedy RH, Krishnan JA, M Tags: J Am Med Inform Assoc Source Type: research

PEDSnet: a National Pediatric Learning Health System.
Abstract A learning health system (LHS) integrates research done in routine care settings, structured data capture during every encounter, and quality improvement processes to rapidly implement advances in new knowledge, all with active and meaningful patient participation. While disease-specific pediatric LHSs have shown tremendous impact on improved clinical outcomes, a national digital architecture to rapidly implement LHSs across multiple pediatric conditions does not exist. PEDSnet is a clinical data research network that provides the infrastructure to support a national pediatric LHS. A consortium consisting...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Forrest CB, Margolis PA, Bailey LC, Marsolo K, Del Beccaro MA, Finkelstein JA, Milov DE, Vieland VJ, Wolf BA, Yu FB, Kahn MG Tags: J Am Med Inform Assoc Source Type: research

Developing a data infrastructure for a learning health system: the PORTAL network.
Abstract The Kaiser Permanente & Strategic Partners Patient Outcomes Research To Advance Learning (PORTAL) network engages four healthcare delivery systems (Kaiser Permanente, Group Health Cooperative, HealthPartners, and Denver Health) and their affiliated research centers to create a new national network infrastructure that builds on existing relationships among these institutions. PORTAL is enhancing its current capabilities by expanding the scope of the common data model, paying particular attention to incorporating patient-reported data more systematically, implementing new multi-site data governance proc...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: McGlynn EA, Lieu TA, Durham ML, Bauck A, Laws R, Go AS, Chen J, Feigelson HS, Corley DA, Young DR, Nelson AF, Davidson AJ, Morales LS, Kahn MG Tags: J Am Med Inform Assoc Source Type: research

Changing the research landscape: the New York City Clinical Data Research Network.
DRN Abstract The New York City Clinical Data Research Network (NYC-CDRN), funded by the Patient-Centered Outcomes Research Institute (PCORI), brings together 22 organizations including seven independent health systems to enable patient-centered clinical research, support a national network, and facilitate learning healthcare systems. The NYC-CDRN includes a robust, collaborative governance and organizational infrastructure, which takes advantage of its participants' experience, expertise, and history of collaboration. The technical design will employ an information model to document and manage the collection and t...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Kaushal R, Hripcsak G, Ascheim DD, Bloom T, Campion TR, Caplan AL, Currie BP, Check T, Deland EL, Gourevitch MN, Hart R, Horowitz CR, Kastenbaum I, Levin AA, Low AF, Meissner P, Mirhaji P, Pincus HA, Scaglione C, Shelley D, Tobin JN, on behalf of the NYC- Tags: J Am Med Inform Assoc Source Type: research

The ADVANCE network: accelerating data value across a national community health center network.
Abstract The ADVANCE (Accelerating Data Value Across a National Community Health Center Network) clinical data research network (CDRN) is led by the OCHIN Community Health Information Network in partnership with Health Choice Network and Fenway Health. The ADVANCE CDRN will 'horizontally' integrate outpatient electronic health record data for over one million federally qualified health center patients, and 'vertically' integrate hospital, health plan, and community data for these patients, often under-represented in research studies. Patient investigators, community investigators, and academic investigators with d...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Devoe JE, Gold R, Cottrell E, Bauer V, Brickman A, Puro J, Nelson C, Mayer KH, Sears A, Burdick T, Merrell J, Matthews P, Fields S Tags: J Am Med Inform Assoc Source Type: research

Patient-powered research networks: building capacity for conducting patient-centered clinical outcomes research.
Abstract The Patient-Centered Outcomes Research Institute (PCORI) recently launched PCORnet to establish a single inter-operable multicenter data research network that will support observational research and randomized clinical trials. This paper provides an overview of the patient-powered research networks (PPRNs), networks of patient organizations focused on a particular health condition that are interested in sharing health information and engaging in research. PPRNs will build on their foundation of trust within the patient communities and draw on their expertise, working with participants to identify true pat...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: PCORnet PPRN Consortium, Daugherty SE, Wahba S, Fleurence R Tags: J Am Med Inform Assoc Source Type: research

The Mid-South Clinical Data Research Network.
Abstract The Mid-South Clinical Data Research Network (CDRN) encompasses three large health systems: (1) Vanderbilt Health System (VU) with electronic medical records for over 2 million patients, (2) the Vanderbilt Healthcare Affiliated Network (VHAN) which currently includes over 40 hospitals, hundreds of ambulatory practices, and over 3 million patients in the Mid-South, and (3) Greenway Medical Technologies, with access to 24 million patients nationally. Initial goals of the Mid-South CDRN include: (1) expansion of our VU data network to include the VHAN and Greenway systems, (2) developing data integration/int...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Rosenbloom ST, Harris P, Pulley J, Basford M, Grant J, Dubuisson A, Rothman RL Tags: J Am Med Inform Assoc Source Type: research

Launching PCORnet, a national patient-centered clinical research network.
Abstract The Patient-Centered Outcomes Research Institute (PCORI) has launched PCORnet, a major initiative to support an effective, sustainable national research infrastructure that will advance the use of electronic health data in comparative effectiveness research (CER) and other types of research. In December 2013, PCORI's board of governors funded 11 clinical data research networks (CDRNs) and 18 patient-powered research networks (PPRNs) for a period of 18 months. CDRNs are based on the electronic health records and other electronic sources of very large populations receiving healthcare within integrated or ne...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Fleurence RL, Curtis LH, Califf RM, Platt R, Selby JV, Brown JS Tags: J Am Med Inform Assoc Source Type: research

PCORnet: turning a dream into reality.
PMID: 24821744 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Collins FS, Hudson KL, Briggs JP, Lauer MS Tags: J Am Med Inform Assoc Source Type: research

PaTH: towards a learning health system in the Mid-Atlantic region.
Abstract The PaTH (University of Pittsburgh/UPMC, Penn State College of Medicine, Temple University Hospital, and Johns Hopkins University) clinical data research network initiative is a collaborative effort among four academic health centers in the Mid-Atlantic region. PaTH will provide robust infrastructure to conduct research, explore clinical outcomes, link with biospecimens, and improve methods for sharing and analyzing data across our diverse populations. Our disease foci are idiopathic pulmonary fibrosis, atrial fibrillation, and obesity. The four network sites have extensive experience in using data from e...
Source: Journal of the American Medical Informatics Association - May 12, 2014 Category: Information Technology Authors: Amin W, Tsui FR, Borromeo C, Chuang CH, Espino JU, Ford D, Hwang W, Kapoor W, Lehmann H, Martich GD, Morton S, Paranjape A, Shirey W, Sorensen A, Becich MJ, Hess R, the PaTH network team Tags: J Am Med Inform Assoc Source Type: research

Area-level factors associated with electronic health record adoption and meaningful use in the Regional Extension Center Program.
CONCLUSIONS: Federal efforts to spur EHR adoption and MU have demonstrated some early success; however, some geographic variations in EHR diffusion indicate that greater attention needs to be paid to ensuring equitable uptake and use of EHRs throughout the US. PMID: 24798687 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 5, 2014 Category: Information Technology Authors: Samuel CA Tags: J Am Med Inform Assoc Source Type: research

An iterative evaluation of two shortened systematic review formats for clinicians: a focus group study.
CONCLUSIONS: Primary care physicians provided input on the refinement of two prototypes of a shortened systematic review for clinicians. Their feedback guided changes to the format, presentation, and layout of these prototypes in order to increase usability and uptake for end-users. PMID: 24786378 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - May 1, 2014 Category: Information Technology Authors: Perrier L, Kealey MR, Straus SE Tags: J Am Med Inform Assoc Source Type: research

Informatics support for clinical decisions.
PMID: 24718740 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - April 12, 2014 Category: Information Technology Authors: Ohno-Machado L Tags: J Am Med Inform Assoc Source Type: research

Correction.
Authors: PMID: 24718741 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - April 12, 2014 Category: Information Technology Tags: J Am Med Inform Assoc Source Type: research

Chairman's column: AMIA's policy priorities for 2014.
PMID: 24718742 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - April 12, 2014 Category: Information Technology Authors: Middleton B Tags: J Am Med Inform Assoc Source Type: research

A prospective international cooperative information technology platform built using open-source tools for improving the access to and safety of bone marrow transplantation in low- and middle-income countries.
Abstract Jagriti Innovations developed a collaboration tool in partnership with the Cure2Children Foundation that has been used by health professionals in Italy, Pakistan, and India for the collaborative management of patients undergoing bone marrow transplantation (BMT) for thalassemia major since August 2008. This online open-access database covers data recording, analyzing, and reporting besides enabling knowledge exchange, telemedicine, capacity building, and quality assurance. As of February 2014, over 2400 patients have been registered and 112 BMTs have been performed with outcomes comparable to internationa...
Source: Journal of the American Medical Informatics Association - April 8, 2014 Category: Information Technology Authors: Agarwal RK, Sedai A, Dhimal S, Ankita K, Clemente L, Siddique S, Yaqub N, Khalid S, Itrat F, Khan A, Gilani SK, Marwah P, Soni R, Missiry ME, Hussain MH, Uderzo C, Faulkner L Tags: J Am Med Inform Assoc Source Type: research

Query Health: standards-based, cross-platform population health surveillance.
CONCLUSIONS: Query Health was a test of the learning health system that supplied a functional methodology and reference implementation for distributed population health queries that has been validated at three sites. PMID: 24699371 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - April 3, 2014 Category: Information Technology Authors: Klann JG, Buck MD, Brown J, Hadley M, Elmore R, Weber GM, Murphy SN Tags: J Am Med Inform Assoc Source Type: research

Assessing the similarity of surface linguistic features related to epilepsy across pediatric hospitals.
CONCLUSION: With a reasonably uniform epilepsy vocabulary and an NLP-based algorithm able to use this uniformity to classify epilepsy progress notes across different hospitals, we can pursue automated comparisons of patient conditions, treatments, and diagnoses across different healthcare settings. PMID: 24692393 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - April 1, 2014 Category: Information Technology Authors: Connolly B, Matykiewicz P, Bretonnel Cohen K, Standridge SM, Glauser TA, Dlugos DJ, Koh S, Tham E, Pestian J Tags: J Am Med Inform Assoc Source Type: research

Clinical research data warehouse governance for distributed research networks in the USA: a systematic review of the literature.
CONCLUSIONS: While peer-reviewed, US-based DRN data warehouse governance publications have increased, DRN developers and administrators are encouraged to publish information about these programs. PMID: 24682495 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 28, 2014 Category: Information Technology Authors: Holmes JH, Elliott TE, Brown JS, Raebel MA, Davidson A, Nelson AF, Chung A, La Chance P, Steiner JF Tags: J Am Med Inform Assoc Source Type: research

Paving the COWpath: data-driven design of pediatric order sets.
CONCLUSIONS: We demonstrate that data-driven methods offer a promising approach for designing order sets that are generalizable, data-driven, condition-based, and up to date with current best practices. PMID: 24674844 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 27, 2014 Category: Information Technology Authors: Zhang Y, Padman R, Levin JE Tags: J Am Med Inform Assoc Source Type: research

Impact of electronic reminders on venous thromboprophylaxis after admissions and transfers.
Abstract OBJECTIVE: Clinical decision support has the potential to improve prevention of venous thromboembolism (VTE). The purpose of this prospective study was to analyze the effect of electronic reminders on thromboprophylaxis rates in wards to which patients were admitted and transferred. The latter was of particular interest since patient handoffs are considered to be critical safety issues. METHODS: The trial involved two study periods in the six departments of a university hospital, three of which were randomly assigned to the intervention group displaying reminders during the second period. At 6 h afte...
Source: Journal of the American Medical Informatics Association - March 26, 2014 Category: Information Technology Authors: Beeler PE, Eschmann E, Schumacher A, Studt JD, Amann-Vesti B, Blaser J Tags: J Am Med Inform Assoc Source Type: research

Applying human factors principles to alert design increases efficiency and reduces prescribing errors in a scenario-based simulation.
CONCLUSIONS: This simulation study provides evidence that applying human factors design principles to medication alerts can improve usability and prescribing outcomes. PMID: 24668841 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 25, 2014 Category: Information Technology Authors: Russ AL, Zillich AJ, Melton BL, Russell SA, Chen S, Spina JR, Weiner M, Johnson EG, Daggy JK, McManus MS, Hawsey JM, Puleo AG, Doebbeling BN, Saleem JJ Tags: J Am Med Inform Assoc Source Type: research

A personally controlled electronic health record for Australia.
CONCLUSIONS: The PCEHR is aimed at connecting all participants and their interventions, and is intended to become a system-wide activity. PMID: 24650635 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 20, 2014 Category: Information Technology Authors: Pearce C, Bainbridge M Tags: J Am Med Inform Assoc Source Type: research

Design and usability study of an iconic user interface to ease information retrieval of medical guidelines.
CONCLUSIONS: VCM was successfully implemented in DC as an option. It increased the success rate of information retrieval tasks, despite requiring slightly more time, and was well accepted by end-users. PMID: 24650636 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 20, 2014 Category: Information Technology Authors: Griffon N, Kerdelhué G, Hamek S, Hassler S, Boog C, Lamy JB, Duclos C, Venot A, Darmoni SJ Tags: J Am Med Inform Assoc Source Type: research

Machine learning-based prediction of drug-drug interactions by integrating drug phenotypic, therapeutic, chemical, and genomic properties.
CONCLUSIONS: Through machine learning-based integration of drug phenotypic, therapeutic, structural, and genomic similarities, we demonstrated that HNAI is promising for uncovering DDIs in drug development and postmarketing surveillance. PMID: 24644270 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 18, 2014 Category: Information Technology Authors: Cheng F, Zhao Z Tags: J Am Med Inform Assoc Source Type: research

MedXN: an open source medication extraction and normalization tool for clinical text.
CONCLUSIONS: The MedXN system (http://sourceforge.net/projects/ohnlp/files/MedXN/) was able to extract comprehensive medication information with high accuracy and demonstrated good normalization capability to RxCUI as long as explicit evidence existed. More sophisticated inference rules might result in further improvements to specific RxCUI assignments for incomplete medication descriptions. PMID: 24637954 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 17, 2014 Category: Information Technology Authors: Sohn S, Clark C, Halgrim SR, Murphy SP, Chute CG, Liu H Tags: J Am Med Inform Assoc Source Type: research

Racial differences in cancer screening with electronic health records and electronic preventive care reminders.
CONCLUSIONS: In this visit-based analysis, non-white patients had higher colon cancer screening order rates than white patients. Despite hopes and fears about HIT, EHRs and e-reminders did not ameliorate or exacerbate racial differences in cancer screening order rates. PMID: 24637955 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 17, 2014 Category: Information Technology Authors: Mishuris RG, Linder JA Tags: J Am Med Inform Assoc Source Type: research

Reliability and validity of the American Hospital Association's national longitudinal survey of health information technology adoption.
CONCLUSIONS: The analyzed instrument exhibits satisfactory reliability and validity. PMID: 24623194 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 12, 2014 Category: Information Technology Authors: Everson J, Lee SY, Friedman CP Tags: J Am Med Inform Assoc Source Type: research

Comparing the information seeking strategies of residents, nurse practitioners, and physician assistants in critical care settings.
CONCLUSIONS: The differences in the information seeking strategies are potentially a result of the differences in clinical training, strategies of managing cognitive load, and the nature of the use of available health IT tools. Further research is needed to investigate the effects of these differences on clinical and process outcomes. PMID: 24619926 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - March 11, 2014 Category: Information Technology Authors: Kannampallil TG, Jones LK, Patel VL, Buchman TG, Franklin A Tags: J Am Med Inform Assoc Source Type: research

Lessons learned from the introduction of an electronic safety net to enhance test result management in an Australian mothers' hospital.
This study describes the implementation and impact of an electronic test result acknowledgement (RA) system in the Mater Mothers' Hospital in Brisbane, Australia. The Verdi application electronically records clinicians' acknowledgement of the review of results. Hospital data (August 2011-August 2012) were extracted to measure clinicians' acknowledgement practices. There were 27 354 inpatient test results for 6855 patients. All test results were acknowledged. 60% (95% CI 59% to 61%) of laboratory and 44% (95% CI 40% to 48%) of imaging results were acknowledged within 24 h. The median time between report availability and ack...
Source: Journal of the American Medical Informatics Association - March 5, 2014 Category: Information Technology Authors: Georgiou A, Lymer S, Forster M, Strachan M, Graham S, Hirst G, Callen J, Westbrook JI Tags: J Am Med Inform Assoc Source Type: research

NIH's Big Data to Knowledge initiative and the advancement of biomedical informatics.
PMID: 24509598 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - February 12, 2014 Category: Information Technology Authors: Ohno-Machado L Tags: J Am Med Inform Assoc Source Type: research

What Big Data means to me.
PMID: 24509599 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - February 12, 2014 Category: Information Technology Authors: Bourne PE Tags: J Am Med Inform Assoc Source Type: research

First diplomates board certified in the subspecialty of clinical informatics.
PMID: 24509600 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - February 12, 2014 Category: Information Technology Authors: Middleton B Tags: J Am Med Inform Assoc Source Type: research

Agreement of Medicaid claims and electronic health records for assessing preventive care quality among adults.
Abstract To compare the agreement of electronic health record (EHR) data versus Medicaid claims data in documenting adult preventive care. Insurance claims are commonly used to measure care quality. EHR data could serve this purpose, but little information exists about how this source compares in service documentation. For 13 101 Medicaid-insured adult patients attending 43 Oregon community health centers, we compared documentation of 11 preventive services, based on EHR versus Medicaid claims data. Documentation was comparable for most services. Agreement was highest for influenza vaccination (κ =&th...
Source: Journal of the American Medical Informatics Association - February 7, 2014 Category: Information Technology Authors: Heintzman J, Bailey SR, Hoopes MJ, Le T, Gold R, O'Malley JP, Cowburn S, Marino M, Krist A, Devoe JE Tags: J Am Med Inform Assoc Source Type: research

How outcomes are achieved through patient portals: a realist review.
CONCLUSIONS: Patient portals may impact clinical outcomes and health service delivery through multiple mechanisms. Given the relative uniformity of evaluation contexts, we were not able to detect patterns in how patient portals work in different contexts. Nonetheless, it appears from the overwhelming proportion of patient portal evaluations coming from integrated health service networks, that these networks provide more fertile contexts for patient portals to be effective. To improve the understanding of how patient portals work, future evaluations of patient portals should capture information about mechanisms and context ...
Source: Journal of the American Medical Informatics Association - February 6, 2014 Category: Information Technology Authors: Otte-Trojel T, de Bont A, Rundall TG, van de Klundert J Tags: J Am Med Inform Assoc Source Type: research

Sensitivity and specificity of dosing alerts for dosing errors among hospitalized pediatric patients.
CONCLUSIONS: The dosing alert system had a low sensitivity and positive predictive value for dosing errors, but might have prevented dosing errors from reaching patients. Customization increased the sensitivity of the system for dosing errors. PMID: 24496386 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - February 4, 2014 Category: Information Technology Authors: Stultz JS, Porter K, Nahata MC Tags: J Am Med Inform Assoc Source Type: research

DCMDSM: a DICOM decomposed storage model.
CONCLUSIONS: DCMDSM is a model built for the storage of heterogeneous DICOM content, based on a straightforward database design. The results obtained through its evaluation attest its suitability as a storage layer for projects where DICOM images are stored once, and queried/retrieved whenever necessary. PMID: 24491269 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - February 3, 2014 Category: Information Technology Authors: Savaris A, Härder T, von Wangenheim A Tags: J Am Med Inform Assoc Source Type: research

Electronic health record systems: risks and benefits.
PMID: 24453123 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - January 25, 2014 Category: Information Technology Authors: Ohno-Machado L Tags: J Am Med Inform Assoc Source Type: research

Finding influential users of online health communities: a new metric based on sentiment influence.
Abstract OBJECTIVE: Online health communities (OHCs) have become a major source of support for people with health problems. This research tries to improve our understanding of social influence and to identify influential users in OHCs. The outcome can facilitate OHC management, improve community sustainability, and eventually benefit OHC users. METHODS: Through text mining and sentiment analysis of users' online interactions, the research revealed sentiment dynamics in threaded discussions. A novel metric-the number of influential responding replies-was proposed to directly measure a user's ability to affect ...
Source: Journal of the American Medical Informatics Association - January 21, 2014 Category: Information Technology Authors: Zhao K, Yen J, Greer G, Qiu B, Mitra P, Portier K Tags: J Am Med Inform Assoc Source Type: research

An interactive Bayesian model for prediction of lymph node ratio and survival in pancreatic cancer patients.
CONCLUSIONS: We provide a new approach and tool set for the prediction of LNR and survival that are generally applicable to a host of cancer types, including breast, colon, melanoma, and stomach. Our methods are illustrated with the development of a validated model and web applications for the prediction of survival in a large set of pancreatic cancer patients. PMID: 24444460 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - January 20, 2014 Category: Information Technology Authors: Smith BJ, Mezhir JJ Tags: J Am Med Inform Assoc Source Type: research

Word sense disambiguation in the clinical domain: a comparison of knowledge-rich and knowledge-poor unsupervised methods.
CONCLUSIONS: Topic modeling for WSD provides superior results in the clinical domain; however, integration of knowledge remains to be effectively exploited. PMID: 24441986 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - January 17, 2014 Category: Information Technology Authors: Chasin R, Rumshisky A, Uzuner O, Szolovits P Tags: J Am Med Inform Assoc Source Type: research

Automatic lymphoma classification with sentence subgraph mining from pathology reports.
CONCLUSIONS: We compare our system with three baseline classifiers using standard n-grams, full MetaMap concepts, and filtered MetaMap concepts. Our system achieves high F-measures on multiple binary classifications of lymphoma (Burkitt lymphoma, 0.8; diffuse large B-cell lymphoma, 0.909; follicular lymphoma, 0.84; Hodgkin lymphoma, 0.912). Significance tests show that our system outperforms all three baselines. Moreover, feature analysis identifies subgraph features that contribute to improved performance; these features agree with the state-of-the-art knowledge about lymphoma classification. We also highlight how these u...
Source: Journal of the American Medical Informatics Association - January 15, 2014 Category: Information Technology Authors: Luo Y, Sohani AR, Hochberg EP, Szolovits P Tags: J Am Med Inform Assoc Source Type: research

Evaluation of medium-term consequences of implementing commercial computerized physician order entry and clinical decision support prescribing systems in two 'early adopter' hospitals.
CONCLUSIONS: We identified little difference in the medium-term consequences of a CPOE and a CDS system. It is important that future studies investigate the medium- and longer-term consequences of CPOE and CDS systems in a wider range of hospitals. PMID: 24431334 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - January 15, 2014 Category: Information Technology Authors: Cresswell KM, Bates DW, Williams R, Morrison Z, Slee A, Coleman J, Robertson A, Sheikh A Tags: J Am Med Inform Assoc Source Type: research

Electronic health record functionality needed to better support primary care.
This article presents a consensus statement about gaps in current EHR functionality and needed enhancements to support primary care. The Institute of Medicine primary care attributes were used to define needs and meaningful use (MU) objectives to define EHR functionality. Current objectives remain focused on disease rather than the whole person, ignoring factors such as personal risks, behaviors, family structure, and occupational and environmental influences. Primary care needs EHRs to move beyond documentation to interpreting and tracking information over time, as well as patient-partnering activities, support for team-b...
Source: Journal of the American Medical Informatics Association - January 15, 2014 Category: Information Technology Authors: Krist AH, Beasley JW, Crosson JC, Kibbe DC, Klinkman MS, Lehmann CU, Fox CH, Mitchell JM, Mold JW, Pace WD, Peterson KA, Phillips RL, Post R, Puro J, Raddock M, Simkus R, Waldren SE Tags: J Am Med Inform Assoc Source Type: research

Assisted annotation of medical free text using RapTAT.
CONCLUSIONS: Pre-annotations generated by a tool capable of interactive training can reduce the time required to create an annotated document corpus by up to 50%. PMID: 24431336 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - January 15, 2014 Category: Information Technology Authors: Gobbel GT, Garvin J, Reeves R, Cronin RM, Heavirland J, Williams J, Weaver A, Jayaramaraja S, Giuse D, Speroff T, Brown SH, Xu H, Matheny ME Tags: J Am Med Inform Assoc Source Type: research

Data use and effectiveness in electronic surveillance of healthcare associated infections in the 21st century: a systematic review.
CONCLUSIONS: Driven by the increased availability of electronic patient data, electronic HAI surveillance systems use more data, making systems more sensitive yet less specific, but also allow systems to be tailored to the needs of healthcare institutes' surveillance programs. PMID: 24421290 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - January 13, 2014 Category: Information Technology Authors: de Bruin JS, Seeling W, Schuh C Tags: J Am Med Inform Assoc Source Type: research

Influenza detection from emergency department reports using natural language processing and Bayesian network classifiers.
Abstract OBJECTIVES: To evaluate factors affecting performance of influenza detection, including accuracy of natural language processing (NLP), discriminative ability of Bayesian network (BN) classifiers, and feature selection. METHODS: We derived a testing dataset of 124 influenza patients and 87 non-influenza (shigellosis) patients. To assess NLP finding-extraction performance, we measured the overall accuracy, recall, and precision of Topaz and MedLEE parsers for 31 influenza-related findings against a reference standard established by three physician reviewers. To elucidate the relative contribution of NL...
Source: Journal of the American Medical Informatics Association - January 9, 2014 Category: Information Technology Authors: Ye Y, Tsui FR, Wagner M, Espino JU, Li Q Tags: J Am Med Inform Assoc Source Type: research