Applying operations research to optimize a novel population management system for cancer screening.
CONCLUSIONS: Simulating the impact of changes in staffing, system parameters, and clinical inputs on the effectiveness and efficiency of care can inform the allocation of limited resources in population management. PMID: 24043318 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 16, 2013 Category: Information Technology Authors: Zai AH, Kim S, Kamis A, Hung K, Ronquillo JG, Chueh HC, Atlas SJ Tags: J Am Med Inform Assoc Source Type: research

Engaging patients in medication reconciliation via a patient portal following hospital discharge.
Abstract Few ambulatory medication reconciliation tools exist. Transitions between inpatient and outpatient care can result in medication discrepancies. An interdisciplinary team designed a new 'Secure Messaging for Medication Reconciliation Tool' (SMMRT) within a patient web portal and piloted it among 60 patients at a Veterans Affairs hospital, an integrated system with a shared electronic health record. Recently discharged patients used SMMRT to view their medications in a secure email message and replied using SMMRT's interactive form, verifying their medication regimens and clarifying any inaccuracies. In tot...
Source: Journal of the American Medical Informatics Association - September 13, 2013 Category: Information Technology Authors: Heyworth L, Paquin AM, Clark J, Kamenker V, Stewart M, Martin T, Simon SR Tags: J Am Med Inform Assoc Source Type: research

An integrative review of information systems and terminologies used in local health departments.
CONCLUSIONS: Coordination at a state or national level is recommended to collect information efficiently about LHD information systems that will inform improvements while minimizing duplication of efforts and financial burden. Until this happens, efforts to strengthen LHD information systems and policies may be significantly challenged. PMID: 24036156 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 13, 2013 Category: Information Technology Authors: Olsen J, Baisch MJ Tags: J Am Med Inform Assoc Source Type: research

Automating annotation of information-giving for analysis of clinical conversation.
DISCUSSION: The information-giving ratio is a useful and intuitive measure for predicting patient perception of provider-patient communication quality. These predictions can be made with automated annotation, which is a practical option for studying large collections of clinical encounters with objectivity, consistency, and low cost, providing greater opportunity for training and reflection for care providers. PMID: 24029598 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 12, 2013 Category: Information Technology Authors: Mayfield E, Laws MB, Wilson IB, Penstein Rosé C Tags: J Am Med Inform Assoc Source Type: research

Use of IndiGO individualized clinical guidelines in primary care.
Abstract OBJECTIVE: To determine if IndiGO individualized clinical guidelines could be implemented in routine practice and assess their effects on care and care experience. METHODS: Matched comparison observational design. IndiGO individualized guidelines, based on a biomathematical simulation model, were used in shared decision-making. Physicians and patients viewed risk estimates and tailored recommendations in a dynamic user interface and discussed them for 5-10 min. Outcome measures were prescribing and dispensing of IndiGO-recommended medications, changes in physiological markers and predicted 5-year ris...
Source: Journal of the American Medical Informatics Association - September 12, 2013 Category: Information Technology Authors: Bellows J, Patel S, Young SS Tags: J Am Med Inform Assoc Source Type: research

A comparison of phenotype definitions for diabetes mellitus.
CONCLUSIONS: Further research focused on defining the clinical characteristics of standard diabetes cohorts is important to identify appropriate phenotype definitions for health, policy, and research. PMID: 24026307 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 11, 2013 Category: Information Technology Authors: Richesson RL, Rusincovitch SA, Wixted D, Batch BC, Feinglos MN, Miranda ML, Hammond WE, Califf RM, Spratt SE Tags: J Am Med Inform Assoc Source Type: research

The pattern of name tokens in narrative clinical text and a comparison of five systems for redacting them.
CONCLUSIONS: The nature and size of name lists have substantial influences on scrubbing success. The use of very large name lists with frequency statistics accounts for much of NLM-NS scrubbing success. PMID: 24026308 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 11, 2013 Category: Information Technology Authors: Kayaalp M, Browne AC, Callaghan FM, Dodd ZA, Divita G, Ozturk S, McDonald CJ Tags: J Am Med Inform Assoc Source Type: research

A novel clinician interface to improve clinician access to up-to-date genetic results.
CONCLUSIONS: Our study results demonstrate that health information technology systems have the potential effectively to assist providers in utilizing genetic information in patient care. PMID: 24013137 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 7, 2013 Category: Information Technology Authors: Wilcox AR, Neri PM, Volk LA, Newmark LP, Clark EH, Babb LJ, Varugheese M, Aronson SJ, Rehm HL, Bates DW Tags: J Am Med Inform Assoc Source Type: research

Patient-reported outcome measures: an on-line system empowering patient choice.
Abstract An innovative web-based system was developed to allow patient-reported outcome measures (PROMs) to be easily administered. Stakeholders guided the design and implementation. The software gives patients access to their current and previous scores. This pilot study focused on patients undergoing arthroscopic subacromial decompression, evaluated using the Oxford shoulder score (OSS). Patients showing good improvement in their OSS were offered the choice to return for routine follow-up clinic appointments, or continue rehabilitation, reassured by their improved score. Thirty-six of 117 patients were eligible....
Source: Journal of the American Medical Informatics Association - September 6, 2013 Category: Information Technology Authors: Wilson J, Arshad F, Nnamoko N, Whiteman A, Ring J, Roy B Tags: J Am Med Inform Assoc Source Type: research

Electronic health record use and preventive counseling for US children and adolescents.
The objective was to assess whether rates of preventive counseling delivered at well child visits (WCVs) differ for practices with basic, fully functional, or no electronic health record (EHR). Cross-sectional analyses of WCVs included in the National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey Electronic Medical Records Supplement, 2007-2010 were performed. Practices with fully functional EHRs documented delivery of 34% more counseling topics than those without an EHR. WCVs with a fully functional EHR lasted 3.5 more minutes than those with a basic EHR. Overall, for each additional ...
Source: Journal of the American Medical Informatics Association - September 6, 2013 Category: Information Technology Authors: Rand CM, Blumkin A, Szilagyi PG Tags: J Am Med Inform Assoc Source Type: research

Comparison of two kinds of interface, based on guided navigation or usability principles, for improving the adoption of computerized decision support systems: application to the prescription of antibiotics.
CONCLUSION: The interface designed according to usability principles was perceived to be more usable and inspired greater confidence among physicians than the guided navigation interface. Consideration of usability principles in the construction of an interface-in particular 'effective information presentation', 'consistency', 'efficient interactions', 'effective use of language', and 'minimizing cognitive load'-seemed to improve perceived usability and confidence in the system. PMID: 24008427 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 5, 2013 Category: Information Technology Authors: Tsopra R, Jais JP, Venot A, Duclos C Tags: J Am Med Inform Assoc Source Type: research

Electronic medical records and physician stress in primary care: results from the MEMO Study.
CONCLUSIONS: Stress may rise for physicians with a moderate number of EMR functions. Time pressure was associated with poor physician outcomes mainly in the high EMR cluster. Work redesign may address these stressors. PMID: 24005796 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 4, 2013 Category: Information Technology Authors: Babbott S, Manwell LB, Brown R, Montague E, Williams E, Schwartz M, Hess E, Linzer M Tags: J Am Med Inform Assoc Source Type: research

Communication spaces.
CONCLUSIONS: Communication spaces offer a model of how work unfolds. Annotations make visible local adaptation that makes technology fit for purpose post-implementation and suggest an important role for annotatable information systems and digital augmentation of the physical environment. PMID: 24005797 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 4, 2013 Category: Information Technology Authors: Coiera E Tags: J Am Med Inform Assoc Source Type: research

Evaluating the impact of pre-annotation on annotation speed and potential bias: natural language processing gold standard development for clinical named entity recognition in clinical trial announcements.
CONCLUSIONS: On every experiment pair, the annotator with the pre-annotated text needed less time to annotate than the annotator with non-labeled text. The time savings were statistically significant. Moreover, the pre-annotation did not reduce the IAA or annotator performance. Dictionary-based pre-annotation is a feasible and practical method to reduce the cost of annotation of clinical named entity recognition in the eligibility sections of clinical trial announcements without introducing bias in the annotation process. PMID: 24001514 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 3, 2013 Category: Information Technology Authors: Lingren T, Deleger L, Molnar K, Zhai H, Meinzen-Derr J, Kaiser M, Stoutenborough L, Li Q, Solti I Tags: J Am Med Inform Assoc Source Type: research

A taste of individualized medicine: physicians' reactions to automated genetic interpretations.
;nfeld T Abstract The potential of pharmacogenomics is well documented, and functionality exploiting this knowledge is about to be introduced into electronic medical records. To explore physicians' reactions to automatic interpretations of genetic tests, we built a prototype with a simple interpretive algorithm. The algorithm was adapted to the needs of physicians handling immunosuppressive treatment during organ transplantation. Nine physicians were observed expressing their thoughts while using the prototype for two patient scenarios. The computer screen and audio were recorded, and the qualitative results trian...
Source: Journal of the American Medical Informatics Association - September 3, 2013 Category: Information Technology Authors: Lærum H, Bremer S, Bergan S, Grünfeld T Tags: J Am Med Inform Assoc Source Type: research

Defining a comprehensive verotype using electronic health records for personalized medicine.
Abstract The burgeoning adoption of electronic health records (EHR) introduces a golden opportunity for studying individual manifestations of myriad diseases, which is called 'EHR phenotyping'. In this paper, we break down this concept by: relating it to phenotype definitions from Johannsen; comparing it to cohort identification and disease subtyping; introducing a new concept called 'verotype' (Latin: vere = true, actually) to represent the 'true' population of similar patients for treatment purposes through the integration of genotype, phenotype, and disease subtype (eg, specific glucose value patt...
Source: Journal of the American Medical Informatics Association - September 3, 2013 Category: Information Technology Authors: Boland MR, Hripcsak G, Shen Y, Chung WK, Weng C Tags: J Am Med Inform Assoc Source Type: research

You and me and the computer makes three: variations in exam room use of the electronic health record.
Abstract Challenges persist on how to effectively integrate the electronic health record (EHR) into patient visits and clinical workflow, while maintaining patient-centered care. Our goal was to identify variations in, barriers to, and facilitators of the use of the US Department of Veterans Affairs (VA) EHR in ambulatory care workflow in order better to understand how to integrate the EHR into clinical work. We observed and interviewed 20 ambulatory care providers across three geographically distinct VA medical centers. Analysis revealed several variations in, associated barriers to, and facilitators of EHR use c...
Source: Journal of the American Medical Informatics Association - September 3, 2013 Category: Information Technology Authors: Saleem JJ, Flanagan ME, Russ AL, McMullen CK, Elli L, Russell SA, Bennett KJ, Matthias MS, Rehman SU, Schwartz MD, Frankel RM Tags: J Am Med Inform Assoc Source Type: research

A qualitative study of the activities performed by people involved in clinical decision support: recommended practices for success.
CONCLUSIONS: A series of activities are performed by sites strong in CDS, and sites adopting CDS should ensure they incorporate these activities into their efforts. PMID: 23999670 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 2, 2013 Category: Information Technology Authors: Wright A, Ash JS, Erickson JL, Wasserman J, Bunce A, Stanescu A, St Hilaire D, Panzenhagen M, Gebhardt E, McMullen C, Middleton B, Sittig DF Tags: J Am Med Inform Assoc Source Type: research

A literature search tool for intelligent extraction of disease-associated genes.
CONCLUSIONS: We implemented a novel publication search tool to find target articles, specifically focused on links between disorders and genotypes. Through comparison against gold-standard manually updated gene-disorder databases and comparison with automated databases of similar functionality we show that our tool can search through the entirety of PubMed to extract the main gene findings for human diseases rapidly and accurately. PMID: 23999671 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - September 2, 2013 Category: Information Technology Authors: Jung JY, Deluca TF, Nelson TH, Wall DP Tags: J Am Med Inform Assoc Source Type: research

Natural language processing: algorithms and tools to extract computable information from EHRs and from the biomedical literature.
PMID: 23935077 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - August 13, 2013 Category: Information Technology Authors: Ohno-Machado L, Nadkarni P, Johnson K Tags: J Am Med Inform Assoc Source Type: research

President's column: operational informatics--expanding the scope of our discipline.
PMID: 23935078 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - August 13, 2013 Category: Information Technology Authors: Fickenscher K Tags: J Am Med Inform Assoc Source Type: research

Joint segmentation and named entity recognition using dual decomposition in Chinese discharge summaries.
CONCLUSIONS: The joint model is efficient and effective in both segmentation and recognition compared with the two individual tasks. The model achieved encouraging results, demonstrating the feasibility of the two tasks. PMID: 23934949 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - August 9, 2013 Category: Information Technology Authors: Xu Y, Wang Y, Liu T, Liu J, Fan Y, Qian Y, Tsujii J, Chang EI Tags: J Am Med Inform Assoc Source Type: research

Leveraging electronic healthcare record standards and semantic web technologies for the identification of patient cohorts.
CONCLUSIONS: This work provides new insights in how archetypes and ontologies can be effectively combined for EHR-driven phenotyping. The methodological approach can be applied to other problems provided that suitable archetypes, ontologies, and classification rules can be designed. PMID: 23934950 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - August 9, 2013 Category: Information Technology Authors: Fernández-Breis JT, Maldonado JA, Marcos M, Legaz-García MD, Moner D, Torres-Sospedra J, Esteban-Gil A, Martínez-Salvador B, Robles M Tags: J Am Med Inform Assoc Source Type: research

Practical implementation of an existing smoking detection pipeline and reduced support vector machine training corpus requirements.
This study aimed to reduce reliance on large training datasets in support vector machine (SVM)-based clinical text analysis by categorizing keyword features. An enhanced Mayo smoking status detection pipeline was deployed. We used a corpus of 709 annotated patient narratives. The pipeline was optimized for local data entry practice and lexicon. SVM classifier retraining used a grouped keyword approach for better efficiency. Accuracy, precision, and F-measure of the unaltered and optimized pipelines were evaluated using k-fold cross-validation. Initial accuracy of the clinical Text Analysis and Knowledge Extraction System (...
Source: Journal of the American Medical Informatics Association - August 6, 2013 Category: Information Technology Authors: Khor R, Yip WK, Bressel M, Rose W, Duchesne G, Foroudi F Tags: J Am Med Inform Assoc Source Type: research

Workshop on using natural language processing applications for enhancing clinical decision making: an executive summary.
This report is a summary of the discussions during the second day of the workshop. Collectively, the workshop presenters and participants emphasized the need for unstructured clinical notes to be included in the decision making workflow and the need for individualized longitudinal data tracking. The workshop also discussed the need to: (1) combine evidence-based literature and patient records with machine-learning and prediction models; (2) provide trusted and reproducible clinical advice; (3) prioritize evidence and test results; and (4) engage healthcare professionals, caregivers, and patients. The overall consensus of t...
Source: Journal of the American Medical Informatics Association - August 6, 2013 Category: Information Technology Authors: Pai VM, Rodgers M, Conroy R, Luo J, Zhou R, Seto B Tags: J Am Med Inform Assoc Source Type: research

Development of a HIPAA-compliant environment for translational research data and analytics.
Abstract High-performance computing centers (HPC) traditionally have far less restrictive privacy management policies than those encountered in healthcare. We show how an HPC can be re-engineered to accommodate clinical data while retaining its utility in computationally intensive tasks such as data mining, machine learning, and statistics. We also discuss deploying protected virtual machines. A critical planning step was to engage the university's information security operations and the information security and privacy office. Access to the environment requires a double authentication mechanism. The first level o...
Source: Journal of the American Medical Informatics Association - August 2, 2013 Category: Information Technology Authors: Bradford W, Hurdle JF, Lasalle B, Facelli JC Tags: J Am Med Inform Assoc Source Type: research

Temporal phenome analysis of a large electronic health record cohort enables identification of hospital-acquired complications.
CONCLUSIONS: The new visual analytical method described in this paper led directly to the identification of numerous hospital-acquired conditions, which could be further explored through an expanded phenotype definition. PMID: 23907284 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - August 1, 2013 Category: Information Technology Authors: Warner JL, Zollanvari A, Ding Q, Zhang P, Snyder GM, Alterovitz G Tags: J Am Med Inform Assoc Source Type: research

A method for controlling complex confounding effects in the detection of adverse drug reactions using electronic health records.
CONCLUSIONS: This data-driven method is effective in controlling for confounding, resulting in either a higher or similar precision when compared with four comparators, has the unique ability to provide insight into confounders for each specific medication-ADR pair, and can be easily adapted to other EHR systems. PMID: 23907285 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - August 1, 2013 Category: Information Technology Authors: Li Y, Salmasian H, Vilar S, Chase H, Friedman C, Wei Y Tags: J Am Med Inform Assoc Source Type: research

Syntactic parsing of clinical text: guideline and corpus development with handling ill-formed sentences.
CONCLUSIONS: We developed guidelines for parsing clinical text and annotated a corpus accordingly. The high intra- and inter-annotator agreement rates showed decent consistency in following the guidelines. The corpus was shown to be useful in retraining a statistical parser that achieved moderate accuracy. PMID: 23907286 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - August 1, 2013 Category: Information Technology Authors: Fan JW, Yang EW, Jiang M, Prasad R, Loomis RM, Zisook DS, Denny JC, Xu H, Huang Y Tags: J Am Med Inform Assoc Source Type: research

A typology of electronic health record workarounds in small-to-medium size primary care practices.
CONCLUSIONS: This workaround typology provides a framework for EHR users to identify and address workarounds in their own practices, and for researchers to examine the effect of different types of EHR workarounds on patient safety, care quality, and efficiency. PMID: 23904322 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 31, 2013 Category: Information Technology Authors: Friedman A, Crosson JC, Howard J, Clark EC, Pellerano M, Karsh BT, Crabtree B, Jaén CR, Cohen DJ Tags: J Am Med Inform Assoc Source Type: research

Using electronic health records data to identify patients with chronic pain in a primary care setting.
CONCLUSIONS: We derived a useful method that combines readily available elements from an EHR to identify chronic pain with high accuracy. This method should prove useful to those interested in identifying chronic pain patients in large datasets for research, evaluation or quality improvement purposes. PMID: 23904323 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 31, 2013 Category: Information Technology Authors: Tian TY, Zlateva I, Anderson DR Tags: J Am Med Inform Assoc Source Type: research

Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data.
CONCLUSIONS: With the increasing availability of whole-slide scanners, analysis of digitized pathology images will become increasingly important in linking morphologic observations with genomic and clinical endpoints. PMID: 23893318 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 25, 2013 Category: Information Technology Authors: Gutman DA, Cobb J, Somanna D, Park Y, Wang F, Kurc T, Saltz JH, Brat DJ, Cooper LA Tags: J Am Med Inform Assoc Source Type: research

Patient-tailored prioritization for a pediatric care decision support system through machine learning.
CONCLUSIONS: This study demonstrates the feasibility of EHR-driven population phenotyping for patient-tailored prioritization of pediatric preventive care services. PMID: 23886921 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 25, 2013 Category: Information Technology Authors: Klann JG, Anand V, Downs SM Tags: J Am Med Inform Assoc Source Type: research

Examining clinical decision support integrity: is clinician self-reported data entry accurate?
Abstract The aim of this study was to assess the accuracy of clinician-entered data in imaging clinical decision support (CDS). We used CDS-guided CT angiography (CTA) for pulmonary embolus (PE) in the emergency department as a case example because it required clinician entry of d-dimer results which could be unambiguously compared with actual laboratory values. Of 1296 patients with CTA orders for suspected PE during 2011, 1175 (90.7%) had accurate d-dimer values entered. In 55 orders (4.2%), incorrectly entered data shielded clinicians from intrusive computer alerts, resulting in potential CTA overuse. Remaining...
Source: Journal of the American Medical Informatics Association - July 25, 2013 Category: Information Technology Authors: Gupta A, Raja AS, Khorasani R Tags: J Am Med Inform Assoc Source Type: research

Ethical and practical challenges to studying patients who opt out of large-scale biorepository research.
Abstract Large-scale biorepositories that couple biologic specimens with electronic health records containing documentation of phenotypic expression can accelerate scientific research and discovery. However, differences between those subjects who participate in biorepository-based research and the population from which they are drawn may influence research validity. While an opt-out approach to biorepository-based research enhances inclusiveness, empirical research evaluating voluntariness, risk, and the feasibility of an opt-out approach is sparse, and factors influencing patients' decisions to opt out are unders...
Source: Journal of the American Medical Informatics Association - July 25, 2013 Category: Information Technology Authors: Rosenbloom ST, Madison JL, Brothers KB, Bowton EA, Clayton EW, Malin BA, Roden DM, Pulley J Tags: J Am Med Inform Assoc Source Type: research

Design-phase prediction of potential cancer clinical trial accrual success using a research data mart.
CONCLUSIONS: The application of this methodology to cancer clinical design would significantly improve cancer clinical research by reducing the costly efforts expended initiating trials that predictably will fail to meet accrual requirements. PMID: 23851466 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 14, 2013 Category: Information Technology Authors: London JW, Balestrucci L, Chatterjee D, Zhan T Tags: J Am Med Inform Assoc Source Type: research

Response to Maojo and Kulikowski.
PMID: 23851442 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 13, 2013 Category: Information Technology Authors: Friedman CP Tags: J Am Med Inform Assoc Source Type: research

Applying active learning to high-throughput phenotyping algorithms for electronic health records data.
CONCLUSIONS: This study demonstrated that AL can be useful in ML-based phenotyping methods. Moreover, AL and feature engineering based on domain knowledge could be combined to develop efficient and generalizable phenotyping methods. PMID: 23851443 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 13, 2013 Category: Information Technology Authors: Chen Y, Carroll RJ, Hinz ER, Shah A, Eyler AE, Denny JC, Xu H Tags: J Am Med Inform Assoc Source Type: research

The impact of electronic health records on people with diabetes in three different emergency departments.
CONCLUSIONS: The presence of prior information in an EHR may be a valuable adjunct in the care of diabetes patients in ED settings but the pattern of impact may vary from ED to ED. PMID: 23842938 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 10, 2013 Category: Information Technology Authors: Speedie SM, Park YT, Du J, Theera-Ampornpunt N, Bershow BA, Gensinger RA, Routhe DT, Connelly DP Tags: J Am Med Inform Assoc Source Type: research

Why common carrier and network neutrality principles apply to the Nationwide Health Information Network (NWHIN).
Abstract The Office of the National Coordinator will be defining the architecture of the Nationwide Health Information Network (NWHIN) together with the proposed HealtheWay public/private partnership as a development and funding strategy. There are a number of open questions-for example, what is the best way to realize the benefits of health information exchange? How valuable are regional health information organizations in comparison with a more direct approach? What is the role of the carriers in delivering this service? The NWHIN is to exist for the public good, and thus shares many traits of the common law not...
Source: Journal of the American Medical Informatics Association - July 9, 2013 Category: Information Technology Authors: Gaynor M, Lenert L, Wilson KD, Bradner S Tags: J Am Med Inform Assoc Source Type: research

A collaborative approach to developing an electronic health record phenotyping algorithm for drug-induced liver injury.
CONCLUSIONS: Phenotyping algorithms developed for rare and complex conditions are likely to require adaptive implementation at multiple institutions. Better approaches are also needed to share algorithms. Early agreement on goals, data sources, and validation methods may improve the portability of the algorithms. PMID: 23837993 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 9, 2013 Category: Information Technology Authors: Overby CL, Pathak J, Gottesman O, Haerian K, Perotte A, Murphy S, Bruce K, Johnson S, Talwalkar J, Shen Y, Ellis S, Kullo I, Chute C, Friedman C, Bottinger E, Hripcsak G, Weng C Tags: J Am Med Inform Assoc Source Type: research

Design and evaluation of the ONC health information technology curriculum.
CONCLUSIONS: The ONC HIT curriculum met its goals for community college programs and will likely continue to be a valuable resource for the larger informatics community in the future. PMID: 23831832 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 5, 2013 Category: Information Technology Authors: Mohan V, Abbott P, Acteson S, Berner ES, Devlin C, Hammond WE, Kukafka R, Hersh W Tags: J Am Med Inform Assoc Source Type: research

e-Measures: insight into the challenges and opportunities of automating publicly reported quality measures.
We describe our experience with automation and the resulting time savings: a reduction by approximately 50% of abstractor time required for one measure set alone (surgical care improvement project). However, our experience illustrates the gap between the current and desired states of automated public quality reporting, which has important implications for measure developers, accrediting entities, EHR vendors, public/private payers, and government. PMID: 23831833 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 5, 2013 Category: Information Technology Authors: Garrido T, Kumar S, Lekas J, Lindberg M, Kadiyala D, Whippy A, Crawford B, Weissberg J Tags: J Am Med Inform Assoc Source Type: research

Literature review of SNOMED CT use.
CONCLUSIONS: The majority of studies focused on 'theoretical' and 'pre-development/design'. This is still encouraging as SNOMED CT is being harmonized with other standardized terminologies and is being evaluated to determine the content coverage of local terms, which is usually one of the first steps towards adoption. Most implementations are not published in the scientific literature, requiring a look beyond the scientific literature to gain insights into SNOMED CT implementations. PMID: 23828173 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 4, 2013 Category: Information Technology Authors: Lee D, de Keizer N, Lau F, Cornet R Tags: J Am Med Inform Assoc Source Type: research

A highly scalable, interoperable clinical decision support service.
CONCLUSIONS: ECRS design, implementation, and use in CDS consortium trials indicate that it provides the flexibility and modularity needed for broad use and performs adequately. Future work will investigate additional CDS patterns, alternative methods of data passing, and further optimizations in ECRS performance. PMID: 23828174 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - July 4, 2013 Category: Information Technology Authors: Goldberg HS, Paterno MD, Rocha BH, Schaeffer M, Wright A, Erickson JL, Middleton B Tags: J Am Med Inform Assoc Source Type: research

Making it personal: translational bioinformatics.
PMID: 23757438 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 17, 2013 Category: Information Technology Authors: Butte AJ, Ohno-Machado L Tags: J Am Med Inform Assoc Source Type: research

Correction.
Authors: PMID: 23757439 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 17, 2013 Category: Information Technology Tags: J Am Med Inform Assoc Source Type: research

President's column: population health--the ultimate application of informatics!
PMID: 23757440 [PubMed - in process] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 17, 2013 Category: Information Technology Authors: Fickenscher KM Tags: J Am Med Inform Assoc Source Type: research

Multiscale segmentation of the skull in MR images for MRI-based attenuation correction of combined MR/PET.
CONCLUSIONS: The multiscale segmentation method is robust and accurate and can be used for MRI-based attenuation correction in combined MR/PET. PMID: 23761683 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 12, 2013 Category: Information Technology Authors: Yang X, Fei B Tags: J Am Med Inform Assoc Source Type: research

Drug repurposing: mining protozoan proteomes for targets of known bioactive compounds.
CONCLUSIONS: Although proteome-wide screens for drug targets have disadvantages, in-silico methods can be developed that are fast, broad, inexpensive, and effective. In-vitro validation of our results for C parvum indicate that the method presented here can be used to construct a library for more directed small molecule screening, or pipelined into structural modeling and docking programs to facilitate target-based drug development. PMID: 23757409 [PubMed - as supplied by publisher] (Source: Journal of the American Medical Informatics Association)
Source: Journal of the American Medical Informatics Association - June 11, 2013 Category: Information Technology Authors: Sateriale A, Bessoff K, Sarkar IN, Huston CD Tags: J Am Med Inform Assoc Source Type: research