Ablation of FAM20C caused short root defects via suppressing the BMP signaling pathway in mice
AbstractShort root defects are prone to cause various periodontal diseases and lead to tooth loss in some serious cases. Studies about the mechanisms governing the development of the root are needed for a  better understanding of the pathogenesis of short root defects. The protein family with sequence similarity 20 group C (FAM20C) is a Golgi casein kinase that has been well studied in the development of tooth crown formation. However, whether FAM20C plays a role in the development of tooth root is still unknown. Thus, we generatedSox2-Cre;Fam20cfl/fl (cKO) mice, in whichFam20c was ablated in both the dental epitheliu...
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - March 22, 2022 Category: ENT & OMF Source Type: research

Significance of bone morphology and quality on the primary stability of orthodontic mini-implants: in vitro comparison between human bone substitute and artificial bone
ConclusionBone defects and bone quality affected the primary stability of implants in terms of ISQ and IPT values. Results for bone model D2 correlated very well with the HB substitution material. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - March 18, 2022 Category: ENT & OMF Source Type: research

Comparison of the short-term effects of facemask therapy preceded by conventional rapid maxillary expansion or by an alternate rapid maxillary expansions and constrictions protocol
ConclusionThe Alt-RAMEC protocol was found to be more effective in the correction of skeletal class  III malocclusion in the short term. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - March 7, 2022 Category: ENT & OMF Source Type: research

A  three-dimensional method to calculate mechanical advantage in mandibular function
ConclusionsBoth landmarks and biomechanical variables showed high reliability and acceptable errors. The proposed method is viable for the 3D mechanical advantage measure. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - March 7, 2022 Category: ENT & OMF Source Type: research

Occlusal plane rotation and orthodontic decompensation: influence on the outcome of surgical correction of class  III malocclusion
ConclusionSufficient dental decompensation is crucial for controlling the sagittal as well as the vertical relationship during surgery. Counterclockwise rotation provides an increase in sagittal projection of the mandibular body at the soft tissue B ‑point. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - March 4, 2022 Category: ENT & OMF Source Type: research

Comparison between stone and digital cast measurements in mixed dentition
ConclusionMeasurements performed on digital models of mixed dentitions can yield clinically acceptable outcomes with OnyxCeph3 ™ software. Both the digital and the analogue measurements were highly reproducible and reliable. Objectivity of the measurements could not be confirmed, as operator experience did make a difference. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - March 3, 2022 Category: ENT & OMF Source Type: research

Evaluation of occlusal function during orthognathic therapy
ConclusionsThe digital occlusal registration method proved to be a  useful diagnostic tool and provided new insights into therapeutic effects in orthognathic patients. By precisely adjusting the occlusal function, masticatory performance improved significantly.Clinical relevanceSevere malocclusion leads to a  significantly lower masticatory performance for patients, which can be improved by orthognathic therapy and captured by digital occlusal registration. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - February 28, 2022 Category: ENT & OMF Source Type: research

Effects of customized resin base on bonding strength of spherical self-ligating brackets
ConclusionsAs the thickness of the resin base increased, the bonding strength of the spherical bracket decreased. However, the required clinical bonding strength was still satisfied when the thickness was less than 2.0  mm. The existence of a resin base could protect the enamel surface from damage caused by debonding. The customization of spherical brackets by tailoring a resin base can be applied in clinical practice because of the clinically acceptable bonding strength. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - February 22, 2022 Category: ENT & OMF Source Type: research

No-primer adhesive vs. self-adhesive resin: bonding strength following LED curing
ConclusionsDecreasing curing time using high-power LED device did not significantly affect SBS. However, the composite type did affect SBS. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - February 22, 2022 Category: ENT & OMF Source Type: research

Can IGF-1 serve as a  reliable skeletal maturity indicator? A meta-analysis
ConclusionsIGF ‑1 would serve as a promising alternative to conventional radiographic skeletal maturity indicators and in predicting the amount of residual mandibular growth. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - February 22, 2022 Category: ENT & OMF Source Type: research

Administration of a  VEGFR‑2-specific MRI contrast agent to assess orthodontic tooth movement
ConclusionsOTM resulted in uptake of the VEGFR-2-specific MRI contrast agent in tension areas of the periodontal ligament. The imaging protocol presented here is useful for the assessment of VEGFR ‑2 expression in tension areas of the periodontal ligament in vivo. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - February 22, 2022 Category: ENT & OMF Source Type: research

Color changes of maxillary and mandibular incisors following surgical orthodontic treatment
ConclusionsOrthognathic surgery showed a  measurable effect on tooth color. However, esthetic disturbance or patient discomfort based on these color and lightness alterations are unlikely, due to their small impact and low perceptibility in a clinical setting. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - February 22, 2022 Category: ENT & OMF Source Type: research

Skeletal and dentoalveolar contributions during Class  II correction with Forsus™ FRD appliances
ConclusionThe Forsus ™ FRD was effective in correcting Class II malocclusion mainly at the dentoalveolar level. The net skeletal and dentoalveolar contributions towards both overjet and molar correction was 13% and 87%, respectively. The improvement in soft tissue profile and chin–throat configuration was statistic ally insignificant. (Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - February 22, 2022 Category: ENT & OMF Source Type: research

Mitteilungen der DGKFO
(Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie)
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - February 22, 2022 Category: ENT & OMF Source Type: research

Procedure using CAD/CAM-manufactured insertion guides for purely mini-implant-borne rapid maxillary expanders
AbstractWith traditional rapid palatal expansion (RPE), orthopaedic forces are transmitted to the skeletal structures via the anchor teeth potentially leading to several unwanted dental side effects. To prevent these issues, tooth –bone-borne or purely bone-borne expanders were introduced using mini-implants in the palate. In this paper, the digitally planned Quadexpander is described which permits palatal expansion with only skeletal anchorage. The use of virtual insertion planning allows for insertion in areas of ideal bo ne, while avoiding roots and vital structures as well as the possibility of insertion into sites w...
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - February 21, 2022 Category: ENT & OMF Source Type: research