Farnesoid X receptor in chronic liver diseases: an immunohistochemical study
J Immunoassay Immunochem. 2023 Sep 4:1-15. doi: 10.1080/15321819.2023.2242920. Online ahead of print.ABSTRACTChronic hepatitis C virus (HCV) related liver diseases are still an ongoing cause of hepatic failure despite the effective role of direct-acting anti-viral agents. Farnesoid X receptor (FXR) agonists have a potential therapeutic effect on the management of chronic liver diseases (CLD). However, data regarding FXR protein expression in human CLDs are limited and conflicting. We aimed to assess the immunohistochemical expression of FXR in HCV-related chronic hepatitis and cirrhosis in comparison with metabolic-associa...
Source: Journal of Immunoassay and Immunochemistry - September 4, 2023 Category: Biochemistry Authors: Dina Sweed Nanis Shawky Holah Esraa Karman Nancy Asaad Shereen Mahmoud Source Type: research