Outcome of Aneurysmal Septum Primum with Non-restrictive Foramen Ovale in Fetuses with Structurally Normal Hearts: A Tertiary Center Experience
We presented twenty-four cases which also had postnatal echocardiographic examination in our hospital. A t the time of diagnosis of ASP, the mean maternal age was 31.1 ± 5.7 years, the mean gestational age was 28.9 ± 5.9 weeks, the mean birth week was 37.4 ± 3.1 weeks, and the mean birth weight was 2940.8 ± 736.6 g. The postnatal first 3 months prevalences of atrial septal ane urysm, patent foramen ovale and, secundum atrial septal defect (ASD) were 12.5%, 12.5%, 20.8% among fetuses with ASP, respectively. ASP may persist after birth and may increase the frequency of secundum ASD. These data sugge...
Source: Journal of Fetal Medicine - March 30, 2020 Category: Perinatology & Neonatology Source Type: research
Outcome of Fetuses with Cavum Velum Interpositi Cyst —Experience of a Tertiary Centre
AbstractCavum velum interpositi is the space between the layers of the tela choroidea of the third ventricle. This space occasionally appears as an anechoic lesion in routine mid-trimester targeted scans because of the presence of fluid inside. This is then called a cavum velum interpositi (CVI) cyst. CVI cyst is a rare finding with varied outcomes. Councellings management are consequently confusing. This study was aimed at assessing the outcome of CVI cysts to g uide the treating clinician and address apprehensions of the expecting couple. Genetic evaluation and MRI to prove the inncocuous nature of CVI cysts ...
Source: Journal of Fetal Medicine - March 25, 2020 Category: Perinatology & Neonatology Source Type: research
Intrauterine Fetal Infections: Do-Able Approaches
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - March 24, 2020 Category: Perinatology & Neonatology Source Type: research
From Baby Steps to Giant Leaps: A Surprisingly Short Journey
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - March 24, 2020 Category: Perinatology & Neonatology Source Type: research
Agenesis of Ductus Venosus: A Case Series
AbstractDuctus venosus agenesis is a rare anomaly which is significantly associated with cardiac, extracardiac and chromosomal anomalies. The prognosis depends on its association with other congenital abnormalities independent of the type of shunt. The aim of this study was to evaluate the ductus venosus in 2nd trimester scans and to evaluate associated congenital malformations associated with agenesis of the ductus venosus and its feto-neonatal outcome. We performed a retrospective study for a 5 year period from November 2015 to November 2019. Of the 8 cases seen, 2 (25%) had an intrahepatic shunt and 6 (75%) pres...
Source: Journal of Fetal Medicine - March 22, 2020 Category: Perinatology & Neonatology Source Type: research
Role of Antenatal Intervention and Pregnancy Outcome in Large Chorioangiomas
AbstractChorioangioma is a non-trophoblastic benign vascular tumour of the placenta affecting fetal outcome. It has no malignant potential. It is usually diagnosed during the 2nd trimester. These are usually found on the fetal side of the placenta, close to the umbilical cord insertion site protruding into the amniotic cavity. Chorioangi omas can be small or large. Small tumours (less than 5 cm) usually have favourable outcome. Large chorioangiomas (more than 5 cm) usually have an unfavourable outcome and may cause maternal complications like pre-eclampsia, preterm labour, placental abruption, placenta previa...
Source: Journal of Fetal Medicine - March 22, 2020 Category: Perinatology & Neonatology Source Type: research
Recent Advances in the Noninvasive Prenatal Testing for Chromosomal Abnormalities Using Maternal Plasma DNA
AbstractNo single invention in the past has created such a rapid and massive impact on clinical obstetric practice as the introduction of noninvasive prenatal screening (NIPS) for chromosomal abnormalities using cell-free DNA in maternal plasma. However, the technology of NIPS which has also been called noninvasive prenatal testing (NIPT) is rapidly evolving. Most clinicians may not be able to fully understand this new technology to enable good clinical practice. This review will be focused on issues that have important clinical implications. NIPT/S is only a screening test and all positive cases must be confirmed by invas...
Source: Journal of Fetal Medicine - March 4, 2020 Category: Perinatology & Neonatology Source Type: research
Change of Editor-in-Chief
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - February 25, 2020 Category: Perinatology & Neonatology Source Type: research
The Role of First Trimester Ultrasonography in Antenatal Care: A Study from a Single Perinatal Institute in India
AbstractThe aim of this study was to assess the role of ultrasound in first the trimester of pregnancy for confirmation of pregnancy, number of fetuses, chorionicity, amnionicity if multiples, viability, assessment of gestational age, identification of structural anomalies and assessment of risk for chromosomal abnormalities. This was a prospective o bservational study. All pregnant women registered within 13+6 weeks were offered a routine scan between 11+0 and 13+6 weeks. All scans were done by obstetricians, fetal medicine specialists or radiologists are accredited by the Fetal Medicine Foundation. All pregnant...
Source: Journal of Fetal Medicine - February 21, 2020 Category: Perinatology & Neonatology Source Type: research
Syphilis in Pregnancy
AbstractSyphilis is a sexually transmitted bacterial disease relevant to pregnancy because it has the potential to cause congenital syphilis if it occurs at any time during pregnancy. An upsurge in cases of syphilis in women and hence congenital syphilis has been reported worldwide recently. 40% of cases can result in spontaneous miscarriages, stillbirth, non-immune hydrops, fetal growth restriction and perinatal death, as well as serious sequelae in liveborn infected children. Pregnancy complications can be avoided by early detection and treatment in the antenatal period. All antenatal women should be screened for syphili...
Source: Journal of Fetal Medicine - February 20, 2020 Category: Perinatology & Neonatology Source Type: research
Chickenpox in Pregnancy
AbstractPregnant women in the tropics like India are more susceptible to varicella zoster infection due to the lower seroprevalence of varicella as compared to temperate regions. Seronegative pregnant women are highly susceptible following a significant exposure owing to the high secondary attack rate of the virus. Fetal transmission could happen transplacentally while neonatal transmission occurs through close contact post partum. Maternal VZV infection could be severe (particularly varicella pneumonia) with high mortality if untreated. Congenital varicella syndrome has an incidence of about 1 –2% and is more likely if ...
Source: Journal of Fetal Medicine - February 17, 2020 Category: Perinatology & Neonatology Source Type: research
Prospective Comparative Evaluation of Performance of Fetal Growth Charts in the Diagnosis of Suboptimal Fetal Growth During Third Trimester Ultrasound Examination in an Unselected South Indian Antenatal Population
AbstractGrowth standards are key tools in assigning fetal smallness. Growth charts are central to this. The availability of growth charts with varying conceptual methodology and design makes their comparison imperative to ensure wise clinical decision making. This was a prospective, descriptive and correlational study performed at two fetal medicine centers, on 1019 unselected third trimester South Indian women with singleton pregnancies. The estimated fetal weight (EFW) was calculated from one dataset per woman using the Hadlock III formula. The EFW centiles were obtained from eight prenatal growth charts: Hadlock, FM...
Source: Journal of Fetal Medicine - February 14, 2020 Category: Perinatology & Neonatology Source Type: research
Normally Grown Non-dysmorphic Stillbirth Post 38 Weeks Gestation and Reduced Fetal Movements: A Matter of Reserve? A Retrospective Study
This study investigates the relationship between placental weight relative to birthweight and risk of stillbirth in non-dysmorphic fetuses ≥ 38 weeks gestation with no evidence of intrauterine growth restriction. This is a retrospective study of stillbirths who underwent post-mortem between 1st Jan 2011 and 31st Dec 2018 in South East Scotland (n = 55). The control group (n = 74) was matched for gestation, age of mother and maternal BMI. There was a significant difference (p = 0.0117) in the mean ratio of birth weight to placental weight (BW:PW) between the stillbirth group (8.17) and control group (7.3...
Source: Journal of Fetal Medicine - February 5, 2020 Category: Perinatology & Neonatology Source Type: research
Cytomegalovirus in Pregnancy
AbstractHuman cytomegalovirus is worldwide the most common pathogen causing teratogenic congenital infection. Maternal cytomegalovirus (CMV) infection is a serious health concern as it is associated with severe birth defects like sensori-neural hearing loss, impairment of cognitive development and cerebral palsy. It is acquired by contact with body fluids and by vertical transmission from mother to fetus. Transmission rates are particularly high after primary infection of women. Unlike rubella infection, past infection with CMV and seropositivity at the time of conception does not confer protection to the fetus. The rate...
Source: Journal of Fetal Medicine - January 28, 2020 Category: Perinatology & Neonatology Source Type: research
Prenatal Embolisation of Giant Chorioangioma Using n -Butyl Cyanoacrylate: Technique, Clinical Course and Perinatal Outcome
We describe a case of giant chorioangioma complicated by high output cardiac dysfunction with imminent hydrops that was treated with embolisation of the feeder artery usingn-butyl cyanoacrylate and discuss how one modality may not fit all cases. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - January 27, 2020 Category: Perinatology & Neonatology Source Type: research
