A Novel Co-occurrence of VACTERL and Closed Neural Tube Defect
We present a case with 4 components of the association—single umbilical artery, an orectal malformation, unilateral renal agenesis and limb abnormalities. There was also a closed neural tube defect-lipomyelomeningocele with tethered cord. The presence of a neural tube defect with VACTERL makes  this a unique case since the reported vertebral anomalies in VACTERL are non dysra phic. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - September 15, 2020 Category: Perinatology & Neonatology Source Type: research

Prenatal Diagnosis of Right Sided Inguinoscrotal Hernia Associated with Severe Growth Restriction in a Fetus with Trisomy 18: A Case Report
We present a case of prenatal diagnosis of right sided fetal inguinoscrotal hernia, with contralateral hydrocele and severe fetal growth restriction confirmed as Trisomy 18 in subsequently performed chromosomal analysis. The index case presented at 35+2 weeks of gestation with a right sided solid scrotal mass with a  regular contour, mixed echogenic texture with a few echo-free areas, a distinctive arterial supply and characteristic peristaltic movements. Fetal demise was noted  one week later. The diagnosis was confirmed by postnatal examination. Prenatal diagnosis of fetal inguinoscrotal hernia should b e followed...
Source: Journal of Fetal Medicine - September 11, 2020 Category: Perinatology & Neonatology Source Type: research

Diagnosis and Management of Fetal Ductus Arteriosus Constriction
We present a series of ductus arteriosus constriction, of which 3 cases were associated with tricuspid regurgitation, 1 case with right sided dominance of the heart and 1 case with moderate to severe right ventricular hypertrophy. Mild cases require close fetal monitoring and severe cases may need urgent delivery. Postnatal prognosis seems to be good in cases of ductal constriction associated with right heart abnormalities as right heart abnormalities resolve in a couple of weeks, although pulmonary hypertension and right ventricular failure are major concerns. P reventive measures include avoiding the use of NSAIDs ...
Source: Journal of Fetal Medicine - September 1, 2020 Category: Perinatology & Neonatology Source Type: research

Importance of Analysis of Arrhythmia Mechanism in Predicting Outcomes in Fetal Bradycardia: A Single-Centre Retrospective Study from a Dedicated Fetal Cardiology Unit in South India
This study aimed to correlate the  arrhythmia mechanism to pregnancy and early postnatal outcomes in fetal bradycardia. This was retrospective study (May 2013–November 2019). Fetuses with sustained bradycardia (heart rate ≤ 100 per minute) were included. Based on arrhythmia mechanism, patients were categorized into 4 group s:Group 1: blocked atrial ectopics, Group 2: second-degree atrioventricular block (AVB), Group 3: complete AVB and group 4: sinus bradycardia. Clinical presentation, need for transplacental therapy, pregnancy and early postnatal outcomes were analysed. A total of 36 patients were included. Me...
Source: Journal of Fetal Medicine - August 26, 2020 Category: Perinatology & Neonatology Source Type: research

First Trimester Ultrasound Evaluation of the Cleft Palate: Midsagittal, Axial or Coronal View-Which View is Best?
ConclusionA combination of all three planes can be used as an effective screening tool but the axial view has more potential for detection of CP in first trimester. However, large scale prospective studies are needed to confirm this observation. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - August 19, 2020 Category: Perinatology & Neonatology Source Type: research

Signal Ambiguity and Misinterpretation of Fetal Heart Rate: A Report of Two Cases and an Overview of Suspicious Patterns
We present two cases where  the Maternal Heart Rate (MHR) artefacts were mistaken for Fetal Heart Rate (FHR). In the first case, MHR masked the severity of fetal distress and caused a delayed and inappropriate management with subsequent poor neonatal outcome. In the second case, MHR was misinterpreted as FHR causing embarra ssment of the birth attendants upon delivery of a dead macerated newborn. FHR should initially and continuously be verified as the actual origin of the signal displayed on the EFHM before any intervention is undertaken. Understanding the EFHM patterns produced by FHR or MHR and the utilization of mo d...
Source: Journal of Fetal Medicine - August 16, 2020 Category: Perinatology & Neonatology Source Type: research

Can the Severity of Intrahepatic Cholestasis of Pregnancy be Predicted by Second Trimester Screening Test Parameters?
ConclusionAn  increase in the AFP, β-hCG, and uE3 MoM values in the triple test can predict the risk of developing severe ICP. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - August 13, 2020 Category: Perinatology & Neonatology Source Type: research

Diagnosis of Infections in Fetus: Ultrasound and Invasive Techniques
AbstractInfections in pregnancy may lead to fetal morbidity and mortality. The major infections which can be transmitted from the mother to the fetus and can probably result in adverse consequences in the prenatal period include toxoplasmosis, rubella, cytomegalovirus (CMV), syphilis, parvovirus, and varicella. Factors determining the risks of transplacental transmission and associated fetal adverse events include the period of gestation at which transmission occurs and the  immunity status of the mother. No single modality can diagnose all fetal infections and consequently prenatal diagnosis of fetal manifestations of i...
Source: Journal of Fetal Medicine - July 31, 2020 Category: Perinatology & Neonatology Source Type: research

First Trimester Diagnosis of Radial Ray Anomaly
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - June 12, 2020 Category: Perinatology & Neonatology Source Type: research

Sonographic Assessment of Fetal Neck Circumference (NC) As a Predictor of Gestational Age
ConclusionThis study derived nomogram for ultrasound measurement of fetal NC in a Northern Nigerian population. However, NC values from this study differ less with an African population than with Caucasian study population. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - June 12, 2020 Category: Perinatology & Neonatology Source Type: research

Umbilical Artery Doppler Indices at the Perivesical Segment in Growth-Restricted Fetuses
AbstractTo compare perinatal outcomes of growth-restricted fetuses with bilateral positive end-diastolic (PED) flow at the perivesical segment (PVC) and growth-restricted fetuses with unilateral or bilateral absent/reverse end-diastolic (ARED) flow at the PVC segment. A total of 119 growth-restricted fetuses with PED flow at the free loop of the umbilical artery were enrolled in this cross-sectional study. Methods The patients were separated into three groups according to presence or absence of the end-diastolic flow at the perivesical segment. Patients with bilateral PED flow at the PVC segment were enrolled in Group1, pa...
Source: Journal of Fetal Medicine - June 12, 2020 Category: Perinatology & Neonatology Source Type: research

Intraventricular Hemorrhage in a Single Fetus of Dichorionic-Diamniotic Gestation: A Case Report and Review of Literature
We report the first case of IVH in a fetus of dichorionic-diamniotic pregnancy that worsened postnatally. Antenatally, magnetic resonance imaging confirmed a large IVH after ventricular abnormalities were detected by prenatal ultrasound (US). At birth, a grade IV IVH diagnosis was made and progressive ventricle dilatation was noted on weekly US. A ventriculoperitoneal shunt was placed and ventricle dilatation was slightly reduced, however, the IVH was essentially unchanged. The infant was discharged in stable condition at 12-weeks-old and chronic neurological dysfunction is expected. IVH is seen in complicated births of pr...
Source: Journal of Fetal Medicine - May 1, 2020 Category: Perinatology & Neonatology Source Type: research

Referral Pattern for Fetal Echocardiography Over 10 Years in a Single Fetal Imaging Centre from Southern India
ConclusionReferral of high-risk cases for FE has increased recently. Abnormal fetal findings in scan or screening tests was significantly associated with fetal CHD. A  significant percentage of CHD was detected in the low-risk group. Strengthening fetal cardiac screening is needed to optimise appropriate risk stratification as well as to increase detection of cardiac anomalies. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - April 29, 2020 Category: Perinatology & Neonatology Source Type: research

SFM India Oriented Guidelines for Ultrasound Establishments During the COVID 19 Pandemic
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - April 10, 2020 Category: Perinatology & Neonatology Source Type: research

Open Neural Tube Defect in a Fetus with MURCS Association: Value Addition of Fetal Autopsy in Counseling
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - April 9, 2020 Category: Perinatology & Neonatology Source Type: research