The Role of First Trimester Ultrasonography in Antenatal Care: A Study from a Single Perinatal Institute in India

AbstractThe aim of this study was to assess the role of  ultrasound in first the trimester of pregnancy for confirmation of pregnancy, number of fetuses, chorionicity, amnionicity if multiples, viability, assessment of gestational age, identification of structural anomalies and assessment of risk for chromosomal abnormalities. This was a prospective o bservational study. All pregnant women registered within 13+6 weeks were  offered a routine scan between 11+0 and 13+6 weeks. All scans were  done by obstetricians, fetal medicine specialists or radiologists are accredited by the Fetal Medicine Foundation. All pregnant women undergoing 11+0 and 13+6 weeks scan were included. Women beyond 14  weeks of pregnancy and referrals from the other centres not delivered at our institute were excluded from the study. A total of 5923 scans were done between January 2016 and June 2017. Complete follow up was available for 2927 women (49.4%), 1925 (32.5%) are ongoing pregnancies and 1071 (18.0 8%) pregnant women were lost to follow up. The median maternal age in our study was 28 years and 349 (5.89%) mothers had advanced (>  35 years) maternal age. Increased nuchal translucency (NT) (>  95th percentile) was found in 272 cases (4.59%). Intra-uterine fetal death, miscarriages, termination of pregnancy and cardiac abnormalities were higher among women with an NT >  95th ...
Source: Journal of Fetal Medicine - Category: Perinatology & Neonatology Source Type: research

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K, Ueland PM, Murphy MM Abstract The association between elevated early pregnancy fasting plasma total homocysteine (tHcy) and miscarriage risk was investigated prospectively in participants (n=544) from the Reus-Tarragona Birth Cohort study. Pregnancy was confirmed before 12 gestational weeks (GW) by ultrasound scan and a fasting blood sample collected. Pregnancies with complications other than miscarriages were excluded. Miscarriages were diagnosed by ultrasound scan and gestational age at the time of miscarriage estimated by embryo size, where possible. Cases in which blood samples were collected more than a we...
Source: Biochimie - Category: Biochemistry Authors: Tags: Biochimie Source Type: research
CONCLUSIONS: First, fetal defects are more common in MC than in DC twin pregnancies, second, first-trimester detection of fetal defects in DC twin pregnancies is similar to that in singleton pregnancies, third, detectability of defects in MC twins is higher than in DC twins, fourth, in twin pregnancies with fetal defects there is a higher intertwin discordance in CRL and incidence of high NT, but the predictive performance of screening by these markers is poor. This article is protected by copyright. All rights reserved. PMID: 31788879 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
Increased nuchal translucency at 11-13 weeks' gestation and pregnancy outcome in twin pregnancies. Ultrasound Obstet Gynecol. 2019 Nov 26;: Authors: Cimpoca B, Syngelaki A, Litwinska E, Muzaferovic A, Nicolaides KH Abstract OBJECTIVES: To investigate the value of increased fetal nuchal translucency thickness (NT) at the 11-13 weeks scan in the prediction of adverse outcome in dichorionic (DC), monochorionic diamniotic (MCDA) and monochorionic monoamniotic (MCMA) twin pregnancies. METHODS: This was a retrospective analysis of prospectively collected data on twin pregnancies undergoin...
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
Conditions:   Pneumonia;   Pleural Effusion;   Renal Colic;   Hepatic Colic or Cholecystitis;   Subcutaneous Abscess or Cyst;   Fracture of Long Bones;   Intra-uterine Pregnancy or Extra-uterine Pregnancy or Miscarriage;   Phlebitis Intervention:   Diagnostic Test: Ultrasound scan Sponsor:   Hospices Civils de Lyon Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsAfter adjustment for maternal characteristics, none of the fertility treatment types were associated with an increased risk of miscarriage compared with naturally conceiving women.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
CONCLUSION: Our study suggests EMV is an uncommon finding following miscarriage and associated with the presence of retained products of conception (confirmed histologically in all cases surgically managed). Expectant management is a safe option in our cohort, with minimal bleeding, although associated with protracted time to resolution. When patients opt for surgery the maximum blood loss was 300mls, but no patient required a blood transfusion or embolization. This article is protected by copyright. All rights reserved. PMID: 31503383 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
CONCLUSIONS: Our data demonstrates no association between the presence of intrauterine haematoma in the first trimester and first trimester miscarriage. However, a relationship with preterm birth independent of the presence of symptoms of pain and bleeding is evident. These women should be counseled about their increased risk of preterm birth and possibly be offered increased surveillance during their pregnancies. This article is protected by copyright. All rights reserved. PMID: 31483898 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
Abstract OBJECTIVES: The aim of this study was to evaluate the natural history and outcome of selective fetal growth restriction (sFGR) in monochorionic diamniotic (MCDA) twin pregnancies, according to the gestational age at onset and the various reported diagnostic criteria, and to quantify the risk of superimposed twin-to-twin transfusion syndrome (TTTS). METHODS: This is a cohort study of MCDA twin pregnancies that had their routine antenatal care from the first trimester at St George's Hospital, London. These pregnancies had ultrasound scans every 2 weeks at 16-24 weeks, and then every 2-3&t...
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
Abstract OBJECTIVE: To examine the performance of the routine 11-13 weeks scan in detecting fetal non-chromosomal abnormalities. METHODS: This was a retrospective study of prospectively collected data from 100,997 singleton pregnancies attending for a routine ultrasound examination for fetal anatomy, according to a standardized protocol, at 11-13 weeks' gestation. All continuing pregnancies had an additional scan at 18-24 weeks and 71,754 had a scan at either 30-34 or 35-37 weeks. The final diagnosis of fetal abnormalities was based on the results of postnatal examination in the case of livebirths and on the ...
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
ConclusionsToxoplasmosis is uncommon in pregnancy with overall incidence of seroconversion and suspected infection in pregnancy of 0.8 per 1000 live births and incidence of congenital toxoplasmosis 0.1 per 1000 live births when applying a strict protocol of screening, follow-up, and treatment. 51.3% (595/1,159) of women referred to our center for suspected infection were actually considered not infected.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
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