Aorta to Right Atrial Tunnel with Postnatal Transcatheter Treatment
We describe in this report, the antenatal find ings noted in ultrasound imaging along with the postnatal presentation and management of this rare congenital anomaly. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - September 11, 2016 Category: Perinatology & Neonatology Source Type: research
Joubert Syndrome: Classic Sonographic Signs at 19 Weeks of Gestation
AbstractJoubert syndrome is a rare condition with an incidence of 1:100,000. It has primarily an autosomal recessive inheritance pattern. It is characterized by episodic hyperpnea, ataxia, hypotonia, abnormal eye movements, and varying degrees of intellectual disability. The causative genetic mutations are identifiable in only 50 % of the cases. Hence, neuroimaging in correlation with clinical features form the mainstay in the diagnosis of this entity. The classic imaging appearance is the ‘molar-tooth’ sign in the midbrain which was first described on MRI. The fourth ventricle has a bat-wing or umbrella-like configu...
Source: Journal of Fetal Medicine - September 7, 2016 Category: Perinatology & Neonatology Source Type: research
Basic Biostatistical Concepts for the Fetal Physician —I: The 2 × 2 Table and Its Derivatives
AbstractIn the field of fetal medicine, correct interpretation and optimal utilization of diagnostic tests and signs have a major impact on the pregnancy outcome. The attributes of a diagnostic test, such as sensitivity and specificity, and the attributes of a test result such as positive and negative predictive values, and positive and negative likelihood ratios are important yet poorly utilized concepts in clinical practice. This paper explains these concepts using simple language and examples from the fetal medicine literature. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - August 29, 2016 Category: Perinatology & Neonatology Source Type: research
Diachorionic Triamniotic Triplets —Saline Cardiac Tamponade for Fetal Reduction: A Novel Approach
AbstractArtificial reproductive techniques are helping the infertile couples to conceive but with an inherent risk of multifetal pregnancy. Multifetal pregnancies more so; multiple monochorionic pregnancies endanger both the fetus and the mother with an increased risk for morbidity and pregnancy loss. The reduction of multifetal pregnancy using Potassium chloride (KCl) is a usual procedure to reduce multiple pregnancies; but gets complicated in case of monochorionic multiple pregnancies like diachorionic trimnioitc triplets in which KCl cannot be used. In this scenario, the usual procedure for fetal reduction might endange...
Source: Journal of Fetal Medicine - August 21, 2016 Category: Perinatology & Neonatology Source Type: research
Fetal Growth Restriction (FGR): How the Differences Between Early and Late FGR Impact on Clinical Management?
AbstractFetal growth restriction (FGR) is associated with significantly increased perinatal mortality as well as immediate and long-term morbidity. One of the most challenging aspects of this condition is the ability to accurately define and adequately diagnose it in order to determine appropriate clinical management. Within a common pathogenesis of placental insufficiency, two phenotypes, early and late FGR, have emerged. Early FGR is easier to diagnose, however, as a consequence of extreme prematurity at presentation it can be extremely challenging to manage. Late fetal growth restriction is much more problematic to diag...
Source: Journal of Fetal Medicine - August 8, 2016 Category: Perinatology & Neonatology Source Type: research
Journal Watch
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - July 28, 2016 Category: Perinatology & Neonatology Source Type: research
Aubrey Milunsky and Jeff M. Milunsky: Genetic Disorders and the Fetus —Diagnosis, Prevention, and Treatment
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - July 25, 2016 Category: Perinatology & Neonatology Source Type: research
Recognition of Normal Fetal Cardiac Structures
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > Fetal heart examination requires in depth knowledge of fetal cardiac physiology and fetal cardiac anatomy. Therefore, the cardiac sonographer must possess considerable skills to acquire optimum images on cardiac anatomy on predefined standard views. An appropriate interpretation of acquired fetal cardiac images is also a basic requirement that is expected from a cardiac sonographer. Any cardiac ultrasound operator who performs the fetal heart scan is expected to recognize normal cardiac structures, to assess myocardial function and heart rhythm b...
Source: Journal of Fetal Medicine - July 24, 2016 Category: Perinatology & Neonatology Source Type: research
Ultrasonographic Evaluation of Neural Tube Defects at 11 –14 Weeks
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > Fetal neural tube defects are the second most common serious fetal birth defects. In fetuses with open spina bifida there is leakage of cerebrospinal fluid into the amniotic cavity which causes hypertension in the subarachnoid space leading to caudal displacement of the brain. The cranial signs (lemon and banana) are detectable during the second trimester scan. In the first trimester, there are alterations in the appearance of the posterior brain at 11 –13 weeks. In fetuses with open spina bifida, the posterior shift of the brain is evident from...
Source: Journal of Fetal Medicine - July 12, 2016 Category: Perinatology & Neonatology Source Type: research
Ultrasonographic Evaluation of Neural Tube Defects at 11–14 Weeks
Abstract
Fetal neural tube defects are the second most common serious fetal birth defects. In fetuses with open spina bifida there is leakage of cerebrospinal fluid into the amniotic cavity which causes hypertension in the subarachnoid space leading to caudal displacement of the brain. The cranial signs (lemon and banana) are detectable during the second trimester scan. In the first trimester, there are alterations in the appearance of the posterior brain at 11–13 weeks. In fetuses with open spina bifida, the posterior shift of the brain is evident from the first trimester, resulting in compression of ...
Source: Journal of Fetal Medicine - July 12, 2016 Category: Perinatology & Neonatology Source Type: research
Down Syndrome Screening: Evidence that Test Results Differ According to Phenotype
Abstract
The purpose of the present study was to examine screening marker levels in Down syndrome (DS) pregnancies with and without cardiac defects and in euploid pregnancies. Retrospective series in two centers with one or more markers—ultrasound nuchal translucency (NT), first trimester maternal serum pregnancy associated plasma protein (PAPP-A), free-β human chorionic gonadotrophin (free β-hCG), and second trimester serum α-fetoprotein (AFP), unconjugated estriol (uE3), hCG, and free-β hCG. Levels were expressed as multiples of the gestation-specific median (MoM). Differences were assessed by the...
Source: Journal of Fetal Medicine - July 11, 2016 Category: Perinatology & Neonatology Source Type: research
Demystifying Posterior Cranial Fossa Lesions in the Fetus
Abstract
Posterior fossa lesions are rare. Introduction of high resolution ultrasound with 3D reconstruction and endovaginal evaluation of fetal brain through the fontanelle helps in better understanding of neuroanatomy. MRI is often used as an additional tool for evaluation in addition to ultrasound studies. Major components of posterior fossa such as cerebellar hemispheres, vermis, fourth ventricle, cisterna magna, and their normal variants and abnormalities can be demystified by ultrasound studies. Morphometry of these structures helps in the diagnoses of these abnormalities. (Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - June 15, 2016 Category: Perinatology & Neonatology Source Type: research
Prevalence and Relationship Between Maternal Periodontal Disease and Preterm Low Birth Weight Baby
The objective of this study was to examine the prevalence and relationship between maternal periodontal disease and preterm low birth weight (LBW) babies among women delivering at Hindu Rao Hospital, Delhi, India. A case control study was performed on 150 women fulfilling the selection criteria over a period of one year. The study consisted of 50 cases, (women delivering preterm babies weighing ≤2.5 kg, Group I) and 100 controls (women delivering babies at ≥37 weeks and weighing >2.5 kg, Group II). Associated risk factors for preterm low birth weight (PT-LBW) were ascertained by means of a structured questionnai...
Source: Journal of Fetal Medicine - June 7, 2016 Category: Perinatology & Neonatology Source Type: research
Fraser Syndrome: Prenatal Detection at 16 Weeks of Gestation
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > Fraser syndrome is a rare autosomal recessive disorder characterized by syndactyly, renal abnormalities, genital malformation, and in some cases, cryptophthalmos. This syndrome had been diagnosed in the second pregnancy of a 22-year-old woman at 22 weeks of gestation based on prenatal scan, postnatal clinical examination, and autopsy findings. The third pregnancy was uneventful. In the fourth pregnancy, features of Fraser syndrome were evident in the first trimester 11–14 week aneuploidy scan. A review scan at 16 weeks of gestation confi rmed...
Source: Journal of Fetal Medicine - May 31, 2016 Category: Perinatology & Neonatology Source Type: research
Smith –Lemli–Opitz Syndrome (SLOS) and the Fetus
(Source: Journal of Fetal Medicine)
Source: Journal of Fetal Medicine - May 31, 2016 Category: Perinatology & Neonatology Source Type: research
