Syphilis in Pregnancy

AbstractSyphilis is a sexually transmitted bacterial disease relevant to pregnancy because it has the potential to cause congenital syphilis if it occurs at any time during pregnancy. An upsurge in cases of syphilis in women and hence congenital syphilis has been reported worldwide recently. 40% of cases can result in spontaneous miscarriages, stillbirth, non-immune hydrops, fetal growth restriction and perinatal death, as well as serious sequelae in liveborn infected children. Pregnancy complications can be avoided by early detection and treatment in the antenatal period. All antenatal women should be screened for syphilis at the first antenatal visit. There is no gold standard for diagnostic test of syphilis. A combination of serological tests consisting of treponemal and a non treponemal test are used for diagnosis. Screening with non-treponemal tests such as rapid plasma reagin or venereal disease research laboratory test combined with confirmation of reactive individuals with treponemal tests such as the fluorescent treponemal antibody absorption assay is the usual cost effective approach. Those at risk should be retested in the third trimester. Treatment during pregnancy should be with penicillin depending upon the stage of the maternal infection. All neonates born to mothers who have reactive nontreponemal and treponemal test results should be evaluated.
Source: Journal of Fetal Medicine - Category: Perinatology & Neonatology Source Type: research

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Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Jurisprudence, Laws, Legislation, Policies, Rules Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Young Adults Source Type: news
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Source: Journal of the American Academy of Physician Assistants - Category: Primary Care Tags: CME: Women's Health Source Type: research
The introduction of noninvasive prenatal screening (NIPS) using cell-free DNA (cfDNA) is the newest option for aneuploidy screening during pregnancy. Compared with other aneuploidy screening options, NIPS offers a higher detection rate for trisomy 21 with a low false-positive rate. However, pretest and post-test patient counseling is essential and should include a discussion of the benefits and limitations, the screening rather than diagnostic nature of the test, and the association of a test failure with an increased risk of aneuploidy. Refer patients for genetic counseling when appropriate, particularly if test failure o...
Source: Journal of the American Academy of Physician Assistants - Category: Primary Care Tags: Special Topics in Prenatal Medicine Source Type: research
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Source: Tubal Reversal Blog - Category: Reproduction Medicine Authors: Tags: basal body temperature clomid Femera lh testing menstruation metformin ovulation ovulation testing period pregnancy Source Type: blogs
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Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
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Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
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Source: Frontiers in Neurology - Category: Neurology Source Type: research
Sign-up here for a set of week-by-week newsletters so you can follow your baby’s development from now until the beautiful moment of birth. Get Dr. Greene's Pregnancy Newsletter Sign up for Dr. Greene's FREE week-by-week newsletter, timed to your pregnancy to keep you up to date on every stage of your baby's development. Success! Now check your email to confirm your subscription. There was an error submitting your subscription. Please try again. First Name Your baby's due date? ...
Source: Conversations with Dr Greene - Category: Child Development Authors: Tags: Uncategorized Source Type: blogs
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