Bronchiectasis Severity Index and FACED scores in patients with allergic bronchopulmonary aspergillosis complicating asthma: do they correlate with immunological severity or high-attenuation mucus?
Conclusion: We found no correlation between BSI and FACED with immunological parameters in ABPA. However, we found a significant correlation between BSI and FACED and a weak correlation between SGRQ and BHQ. ABPA likely requires a separate disease-severity scoring system.PMID:38520686 | DOI:10.1080/02770903.2024.2334901 (Source: Journal of Asthma)
Source: Journal of Asthma - March 23, 2024 Category: Respiratory Medicine Authors: Shruti Phadnis Valliappan Muthu Inderpaul S Sehgal Kuruswamy T Prasad Sahajal Dhooria Ashutosh N Aggarwal Ritesh Agarwal Source Type: research
Analysis of the Potential Molecular Mechanisms of Asthma and Gastroesophageal Reflux Disease
This study aimed to explore the biological markers related to asthma and GERD by bioinformatics analysis. Initially, gene expression datasets for asthma and GERD were obtained from the GEO database, and subsequent differential expression analysis yielded 620 differentially expressed genes (DEGs) for asthma and 2367 DEGs for GERD. The intersection of these two gene sets yielded a total of 84 DEGs. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses revealed that these genes may be involved in steroid hormone secretion and cellular stress response. Five hub genes (PTGDR2, CPA3, F...
Source: Journal of Asthma - March 22, 2024 Category: Respiratory Medicine Authors: Changdan Chen Wei Zhang Xiujin Zheng Chenglin Jiang Wen Zhang Source Type: research
Prevalence and Predictors of Medication Adherence among Adolescents and Adults with Asthma in Ethiopia: Systematic review and meta-analysis
CONCLUSIONS: The pooled prevalence of medication adherence among adolescents and adults with asthma in Ethiopia is low and indicated that three out of five adolescents and adults with asthma were non-adherent to medications. This implies the ministry of health should develop different strategies to improve medication adherence including patient education and strengthening the health care system. Multicenter longitudinal studies should be further conducted by using objective methods of adherence measurement and large sample size.PMID:38512046 | DOI:10.1080/02770903.2024.2332920 (Source: Journal of Asthma)
Source: Journal of Asthma - March 21, 2024 Category: Respiratory Medicine Authors: Segenet Zewdie Ewunetie Mekashaw Bayked Wondim Ayenew Abyou Seyfu Assefa Andargie Source Type: research
The Association of Infant and Mother Gut Microbiomes with Development of Allergic Diseases in Children: A Systematic Review
ConclusionsThis systematic review shows that gut microbiota may be associated with allergy development. Further studies are required to provide a definitive answer.PMID:38506489 | DOI:10.1080/02770903.2024.2332921 (Source: Journal of Asthma)
Source: Journal of Asthma - March 20, 2024 Category: Respiratory Medicine Authors: Amir-Hossein Mousavian Fateme ZareGarizi Behnaz Ghoreshi Siavash Ketabi Solat Eslami Hanieh-Sadat Ejtahed Mostafa Qorbani Source Type: research
Prevalence of Asthma Triggers and Control Status Among Pediatric Asthmatic Patients in Saudi Arabia
Conclusions: Arabic incense (Bakhour) and psychological stimuli emerged as significant determinants of asthma triggers in Saudi Arabian children diagnosed with asthma. Further studies are warranted to elucidate the physiological mechanisms underpinning the response to Arabic incense (Bakhour).PMID:38506494 | DOI:10.1080/02770903.2024.2332917 (Source: Journal of Asthma)
Source: Journal of Asthma - March 20, 2024 Category: Respiratory Medicine Authors: Mohammed M Alyami Ahmed H Alasimi Abdullah A Alqarni Fahad H Balharith Abdulelah M Aldhahir Source Type: research
The Association of Infant and Mother Gut Microbiomes with Development of Allergic Diseases in Children: A Systematic Review
ConclusionsThis systematic review shows that gut microbiota may be associated with allergy development. Further studies are required to provide a definitive answer.PMID:38506489 | DOI:10.1080/02770903.2024.2332921 (Source: Journal of Asthma)
Source: Journal of Asthma - March 20, 2024 Category: Respiratory Medicine Authors: Amir-Hossein Mousavian Fateme ZareGarizi Behnaz Ghoreshi Siavash Ketabi Solat Eslami Hanieh-Sadat Ejtahed Mostafa Qorbani Source Type: research
Prevalence of Asthma Triggers and Control Status Among Pediatric Asthmatic Patients in Saudi Arabia
Conclusions: Arabic incense (Bakhour) and psychological stimuli emerged as significant determinants of asthma triggers in Saudi Arabian children diagnosed with asthma. Further studies are warranted to elucidate the physiological mechanisms underpinning the response to Arabic incense (Bakhour).PMID:38506494 | DOI:10.1080/02770903.2024.2332917 (Source: Journal of Asthma)
Source: Journal of Asthma - March 20, 2024 Category: Respiratory Medicine Authors: Mohammed M Alyami Ahmed H Alasimi Abdullah A Alqarni Fahad H Balharith Abdulelah M Aldhahir Source Type: research
Efficacy and Safety of Once-Daily Vilanterol/Fluticasone Furoate MDI in Persistent Asthma: Phase 3 OD-INHALE study
Conclusion: Once daily VI/FF pMDI was non-inferior to twice daily FOR/FP pMDI in patients with persistent asthma.PMID:38488853 | DOI:10.1080/02770903.2024.2330485 (Source: Journal of Asthma)
Source: Journal of Asthma - March 15, 2024 Category: Respiratory Medicine Authors: Avdhesh Kumar Manish Kumar Jain Vijaykumar Bhagwan Barge Raghumanda Sunil Kumar Neeraj Gupta Harendra Yadav Amitava Pal Vivek Eknath Redkar Asish Mondal Rahul Kumar Rathore Pavankumar Daultani Ashok Jaiswal Ravi T Mehta Source Type: research
Bacterial antigens and asthma: a comparative study of common respiratory pathogenic bacteria
J Asthma. 2024 Mar 13:1-15. doi: 10.1080/02770903.2024.2330063. Online ahead of print.ABSTRACTIn a previous study we have shown that, in the presence of interleukin (IL)-33, repeated, per-nasal challenge of murine airways with Streptococcus pneumoniae (S. pneumoniae) organisms induces human asthma-like airways inflammation. It is not clear, however, whether this effect is unique or manifest in response to other common respiratory pathogens. To explore this, airways of BALB/c mice were repeatedly challenged per-nasally with formaldehyde-inactivated bacterial bodies in the presence or absence of murine recombinant IL-33. Ser...
Source: Journal of Asthma - March 13, 2024 Category: Respiratory Medicine Authors: Jie Pang Yifan Shi Dan Peng Lele Cui Yingjie Xu Wenjing Wang Yue Hu Yiran Yang Jingjing Wang Xiaofeng Qin Yue Zhang Hao Meng Dan Wang Ge Bai Huihui Yuan Jie Liu Zhe Lv Yan Li Ye Cui Wenjun Wang Kewu Huang Chris J Corrigan Wei Wang Yan Chen Sun Ying Source Type: research
