Possible role of HE4 level elevation in the pathogenesis of TH2-high asthma
CONCLUSION: We found for the first time that HE4 was differentially expressed in the TH2-related asthma subtypes. In TH2-high asthma, HE4 levels were markedly elevated in airway epithelial cells, plasma, induced sputum, and BALF. HE4 may play an important role in various pathogenic mechanisms of asthma, such as airway eosinophilic inflammation, airway mucus secretion, and airway remodelling. HE4 in plasma may be a clinically biomarker for differentiating TH2-related asthma subtypes.PMID:37902273 | DOI:10.1080/02770903.2023.2251056 (Source: Journal of Asthma)
Source: Journal of Asthma - October 30, 2023 Category: Respiratory Medicine Authors: Zhang Kan Cao Yu Tang Hexuan Lin Dang Source Type: research
Comparison of extrafine beclomethasone dipropionate/formoterol fumarate dry powder inhaler and pressurized metered-dose inhaler in Chinese patients with asthma: The FORTUNE study
ConclusionsThe NEXThaler DPI is a similarly effective device to the pMDI for the administration of BDP/FF in adults, so extending the options available for the management of asthma.PMID:37878325 | DOI:10.1080/02770903.2023.2272816 (Source: Journal of Asthma)
Source: Journal of Asthma - October 25, 2023 Category: Respiratory Medicine Authors: Jinping Zheng Jianyong Zhang Xiuhua Fu Lin Changqing Xinri Zhang Xiaodong Mei Corradi Massimo Glauco Cappellini Emanuele Calabro Cissy Zhu Eva Topole Source Type: research
