Correlation between Changes in Serum YKL-40, LXRs, PPM1A, and TGF- β1 Levels and Airway Remodeling and Lung Function in Patients with Bronchial Asthma
CONCLUSION: The severity of bronchial asthma is associated with increased serum levels of YKL-40, LXRα, LXRβ, and TGF-β1 and decreased PPM1A. The levels of YKL-40, PPM1A, and TGF-β1 have a significant correlation with airway remodeling and lung function.PMID:38164946 | DOI:10.1080/02770903.2023.2301426 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: Ying Zhu Bowen Huang Guang Jiang Source Type: research

U-shaped association between 25-Hydroxyvitamin D Concentration and the prevalence of asthma in the overweight and obese U.S. population
CONCLUSIONS: High levels of 25(OH)D are correlated with a diminished prevalence of asthma among overweight and obese individuals in the United States.PMID:38165120 | DOI:10.1080/02770903.2023.2300713 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: XueLi Shi ZiJia Yan Jing Xue CongLi Tian Source Type: research

Pretreatment asthma control test score as a predictive score for clinical remission after bronchial thermoplasty in younger patients with severe asthma and preserved lung function
CONCLUSIONS: To the best of our knowledge, this is the first study to use clinical remission as a criterion for evaluating BT efficacy. The pre-BT ACT score might a the predict response to BT in younger adult patients with severe asthma and pre-BD %FEV1 ≥ 70%.PMID:38163925 | DOI:10.1080/02770903.2023.2297375 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: Fumihiro Kashizaki Kenji Konishi Hao Chen Arihito Tanaka Atsushi Miyasaka Shunsuke Okazaki Chihiro Yamada Nanami Tsuchiya Kentaro Yumoto Harumi Koizumi Kenichi Takahashi Takeshi Kaneko Source Type: research

Correlation between Changes in Serum YKL-40, LXRs, PPM1A, and TGF- β1 Levels and Airway Remodeling and Lung Function in Patients with Bronchial Asthma
CONCLUSION: The severity of bronchial asthma is associated with increased serum levels of YKL-40, LXRα, LXRβ, and TGF-β1 and decreased PPM1A. The levels of YKL-40, PPM1A, and TGF-β1 have a significant correlation with airway remodeling and lung function.PMID:38164946 | DOI:10.1080/02770903.2023.2301426 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: Ying Zhu Bowen Huang Guang Jiang Source Type: research

U-shaped association between 25-Hydroxyvitamin D Concentration and the prevalence of asthma in the overweight and obese U.S. population
CONCLUSIONS: High levels of 25(OH)D are correlated with a diminished prevalence of asthma among overweight and obese individuals in the United States.PMID:38165120 | DOI:10.1080/02770903.2023.2300713 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: XueLi Shi ZiJia Yan Jing Xue CongLi Tian Source Type: research

Pretreatment asthma control test score as a predictive score for clinical remission after bronchial thermoplasty in younger patients with severe asthma and preserved lung function
CONCLUSIONS: To the best of our knowledge, this is the first study to use clinical remission as a criterion for evaluating BT efficacy. The pre-BT ACT score might a the predict response to BT in younger adult patients with severe asthma and pre-BD %FEV1 ≥ 70%.PMID:38163925 | DOI:10.1080/02770903.2023.2297375 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: Fumihiro Kashizaki Kenji Konishi Hao Chen Arihito Tanaka Atsushi Miyasaka Shunsuke Okazaki Chihiro Yamada Nanami Tsuchiya Kentaro Yumoto Harumi Koizumi Kenichi Takahashi Takeshi Kaneko Source Type: research

Correlation between Changes in Serum YKL-40, LXRs, PPM1A, and TGF- β1 Levels and Airway Remodeling and Lung Function in Patients with Bronchial Asthma
CONCLUSION: The severity of bronchial asthma is associated with increased serum levels of YKL-40, LXRα, LXRβ, and TGF-β1 and decreased PPM1A. The levels of YKL-40, PPM1A, and TGF-β1 have a significant correlation with airway remodeling and lung function.PMID:38164946 | DOI:10.1080/02770903.2023.2301426 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: Ying Zhu Bowen Huang Guang Jiang Source Type: research

U-shaped association between 25-Hydroxyvitamin D Concentration and the prevalence of asthma in the overweight and obese U.S. population
CONCLUSIONS: High levels of 25(OH)D are correlated with a diminished prevalence of asthma among overweight and obese individuals in the United States.PMID:38165120 | DOI:10.1080/02770903.2023.2300713 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: XueLi Shi ZiJia Yan Jing Xue CongLi Tian Source Type: research

Pretreatment asthma control test score as a predictive score for clinical remission after bronchial thermoplasty in younger patients with severe asthma and preserved lung function
CONCLUSIONS: To the best of our knowledge, this is the first study to use clinical remission as a criterion for evaluating BT efficacy. The pre-BT ACT score might a the predict response to BT in younger adult patients with severe asthma and pre-BD %FEV1 ≥ 70%.PMID:38163925 | DOI:10.1080/02770903.2023.2297375 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: Fumihiro Kashizaki Kenji Konishi Hao Chen Arihito Tanaka Atsushi Miyasaka Shunsuke Okazaki Chihiro Yamada Nanami Tsuchiya Kentaro Yumoto Harumi Koizumi Kenichi Takahashi Takeshi Kaneko Source Type: research

Correlation between Changes in Serum YKL-40, LXRs, PPM1A, and TGF- β1 Levels and Airway Remodeling and Lung Function in Patients with Bronchial Asthma
CONCLUSION: The severity of bronchial asthma is associated with increased serum levels of YKL-40, LXRα, LXRβ, and TGF-β1 and decreased PPM1A. The levels of YKL-40, PPM1A, and TGF-β1 have a significant correlation with airway remodeling and lung function.PMID:38164946 | DOI:10.1080/02770903.2023.2301426 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: Ying Zhu Bowen Huang Guang Jiang Source Type: research

U-shaped association between 25-Hydroxyvitamin D Concentration and the prevalence of asthma in the overweight and obese U.S. population
CONCLUSIONS: High levels of 25(OH)D are correlated with a diminished prevalence of asthma among overweight and obese individuals in the United States.PMID:38165120 | DOI:10.1080/02770903.2023.2300713 (Source: Journal of Asthma)
Source: Journal of Asthma - January 2, 2024 Category: Respiratory Medicine Authors: XueLi Shi ZiJia Yan Jing Xue CongLi Tian Source Type: research

Global Influence of Dupilumab on Quality of Life in a Severe Asthma Patient with T2 Multimorbidities: A Case Report on Atopic Dermatitis, Chronic Rhinosinusitis with Nasal Polyposis, and Eosinophilic Esophagitis
CONCLUSION: In this case report, a positive and objectively measurable of global improvement on QoL across all four T2 comorbidities was observed after treatment with dupilumab, demonstrating the important role of IL-4 and IL-13 and the existence of a unifying pathological mechanism in T2 diseases.PMID:38152869 | DOI:10.1080/02770903.2023.2300712 (Source: Journal of Asthma)
Source: Journal of Asthma - December 28, 2023 Category: Respiratory Medicine Authors: Monica Colque-Bayona Natalia Hern ández-Cano Margarita Tom ás-Pérez Teresa Caballero Santiago Quirce Javier Dom ínguez-Ortega Source Type: research

Doxofylline as a steroid-sparing treatment in Mexican children with asthma
CONCLUSIONS: Our results suggest that doxofylline may be a steroid-sparing treatment in asthma, but longer-term, controlled studies are needed to confirm these observations.PMID:38153316 | DOI:10.1080/02770903.2023.2294909 (Source: Journal of Asthma)
Source: Journal of Asthma - December 28, 2023 Category: Respiratory Medicine Authors: Sandra Nora Gonz ález-Díaz Ignacio J Ansotegui Carlos Macouzet-S ánchez Natalhie Acu ña-Ortega Carlos de la Cruz-de la Cruz Source Type: research

Exploring the diversity of < em > CFTR < /em > gene mutations in cystic fibrosis individuals of South Asia
CONCLUSION: In summary, the higher prevalence of consanguinity and the limited availability of CF diagnostic resources in South Asia considerably contribute to the prevalence of genetic disorders like CF. The spectrum of CFTR mutations exhibits noticeable variations within South Asian and other populations. The inclusion of current study-enlisted CFTR gene variants is highly recommended for CF disease genetic testing in South Asia which may aid in achieving a precise diagnosis, enhancing disease management, and discovering drugs for currently untreatable genetic variants. It is also imperative to conduct a comprehensive st...
Source: Journal of Asthma - December 28, 2023 Category: Respiratory Medicine Authors: Hassan Rafique Anum Safdar Muhammad Usman Ghani Ali Akbar Farheena Iqbal Awan Zartashay Naeem Ali Amar Mudassar Fareed Awan Syed Wajahat Ullah Rehan Sadiq Shaikh Source Type: research

Application of Different Counseling Strategies for Better Adult Asthma Control
CONCLUSION: The study findings indicate that the combining advanced verbal counseling by incorporating the Asthma smartphone application alongside traditional verbal counseling is a more effective approach for improving asthma control in adults.PMID:38153520 | DOI:10.1080/02770903.2023.2300709 (Source: Journal of Asthma)
Source: Journal of Asthma - December 28, 2023 Category: Respiratory Medicine Authors: Basma M E Mohamed Nabila Laz Haitham Saeed Saleh Alghamdi Mohamed AbdElrahman Mohamed E A Abdelrahim Hoda Rabea Source Type: research