Giant lung cavity due to three different pathogens in a patient receiving inhaled salmeterol plus fluticasone propionate for asthma
CONCLUSION: Tuberculosis and other opportunistic infections are a potential consequence of inhaled corticosteroid use. Clinicians overseeing such patients need to be vigilant about the need for timely investigations about tuberculosis before and during prescribing medications containing inhaled corticosteroids.PMID:38078667 | DOI:10.1080/02770903.2023.2293069 (Source: Journal of Asthma)
Source: Journal of Asthma - December 11, 2023 Category: Respiratory Medicine Authors: Ne şe Merve Güner Zirih Bilge Yilmaz Kara Song ül Özyurt O ğuzhan Okçu Tu ğba İlgar Ünal ŞahiN Source Type: research
AIM2 participates in house dust mite (HDM)-induced epithelial dysfunctions and ovalbumin (OVA)-induced allergic asthma in infant mice
In conclusion, AIM2, up-regulated in severe pediatric allergic asthma, participates in HDM-induced epithelial dysfunctions and OVA-induced allergic asthma progression. Therefore, AIM2 could be a promising target for pediatric allergic asthma treatment regimens, which warrants further in vivo investigations.PMID:38078661 | DOI:10.1080/02770903.2023.2289157 (Source: Journal of Asthma)
Source: Journal of Asthma - December 11, 2023 Category: Respiratory Medicine Authors: Shengzhi Yang Ru Guo Xianmei Meng Yunhong Zhang Source Type: research
Giant lung cavity due to three different pathogens in a patient receiving inhaled salmeterol plus fluticasone propionate for asthma
CONCLUSION: Tuberculosis and other opportunistic infections are a potential consequence of inhaled corticosteroid use. Clinicians overseeing such patients need to be vigilant about the need for timely investigations about tuberculosis before and during prescribing medications containing inhaled corticosteroids.PMID:38078667 | DOI:10.1080/02770903.2023.2293069 (Source: Journal of Asthma)
Source: Journal of Asthma - December 11, 2023 Category: Respiratory Medicine Authors: Ne şe Merve Güner Zirih Bilge Yilmaz Kara Song ül Özyurt O ğuzhan Okçu Tu ğba İlgar Ünal ŞahiN Source Type: research
AIM2 participates in house dust mite (HDM)-induced epithelial dysfunctions and ovalbumin (OVA)-induced allergic asthma in infant mice
In conclusion, AIM2, up-regulated in severe pediatric allergic asthma, participates in HDM-induced epithelial dysfunctions and OVA-induced allergic asthma progression. Therefore, AIM2 could be a promising target for pediatric allergic asthma treatment regimens, which warrants further in vivo investigations.PMID:38078661 | DOI:10.1080/02770903.2023.2289157 (Source: Journal of Asthma)
Source: Journal of Asthma - December 11, 2023 Category: Respiratory Medicine Authors: Shengzhi Yang Ru Guo Xianmei Meng Yunhong Zhang Source Type: research
Giant lung cavity due to three different pathogens in a patient receiving inhaled salmeterol plus fluticasone propionate for asthma
CONCLUSION: Tuberculosis and other opportunistic infections are a potential consequence of inhaled corticosteroid use. Clinicians overseeing such patients need to be vigilant about the need for timely investigations about tuberculosis before and during prescribing medications containing inhaled corticosteroids.PMID:38078667 | DOI:10.1080/02770903.2023.2293069 (Source: Journal of Asthma)
Source: Journal of Asthma - December 11, 2023 Category: Respiratory Medicine Authors: Ne şe Merve Güner Zirih Bilge Yilmaz Kara Song ül Özyurt O ğuzhan Okçu Tu ğba İlgar Ünal ŞahiN Source Type: research
The Role of ACT Score in Mepolizumab Discontinuation
CONCLUSION: In this real-world study, we find that high eosinophil count may not be adequate in screening which individuals will benefit from mepolizumab. Up to 17% of patients fail therapy within 6 months, with male sex and low ACT score increasing risk of mepolizumab discontinuation at Cleveland Clinic.PMID:38064231 | DOI:10.1080/02770903.2023.2293067 (Source: Journal of Asthma)
Source: Journal of Asthma - December 8, 2023 Category: Respiratory Medicine Authors: Neha Solanki Brittany Beck Monica Labadia Kevin Smith Laura Peterson Stephanie King Sarah Micklewright Emily Pennington Sobia Farooq Peng Zhang Mark Aronica Joe Zein Sumita Khatri Suzy Comhair Serpil Erzurum Source Type: research
Progressive clinical effects of the combination omalizumab and HDM - allergen immunotherapy in asthma
CONCLUSION: The combination of HDM SCIT and omalizumab is significantly and progressively reducing ICS use and AX in a 24-month study. The combination is significantly more effective than the single treatments or placebo.PMID:38064236 | DOI:10.1080/02770903.2023.2293057 (Source: Journal of Asthma)
Source: Journal of Asthma - December 8, 2023 Category: Respiratory Medicine Authors: Andrzej Bozek Barbara Rogala Martyna Miodonska Giorgio Walter Canonica Source Type: research
Assessing the risk of intentional self-harm in montelukast users: an updated Sentinel System analysis using ICD-10 coding
CONCLUSION: Our results cannot exclude other neuropsychiatric idiosyncratic reactions to montelukast. Compared to the previous Sentinel study, this study identified about double the rate of self-harm events, suggesting a greater sensitivity of ICD-10 codes for measuring self-harm than ICD-9.PMID:38064517 | DOI:10.1080/02770903.2023.2293064 (Source: Journal of Asthma)
Source: Journal of Asthma - December 8, 2023 Category: Respiratory Medicine Authors: Jummai Apata Jennifer G Lyons Marie C Bradley Yong Ma Maria E Kempner Ivone Kim Efe Eworuke Dinci Pennap Andrew Mosholder Source Type: research
The Role of ACT Score in Mepolizumab Discontinuation
CONCLUSION: In this real-world study, we find that high eosinophil count may not be adequate in screening which individuals will benefit from mepolizumab. Up to 17% of patients fail therapy within 6 months, with male sex and low ACT score increasing risk of mepolizumab discontinuation at Cleveland Clinic.PMID:38064231 | DOI:10.1080/02770903.2023.2293067 (Source: Journal of Asthma)
Source: Journal of Asthma - December 8, 2023 Category: Respiratory Medicine Authors: Neha Solanki Brittany Beck Monica Labadia Kevin Smith Laura Peterson Stephanie King Sarah Micklewright Emily Pennington Sobia Farooq Peng Zhang Mark Aronica Joe Zein Sumita Khatri Suzy Comhair Serpil Erzurum Source Type: research
Progressive clinical effects of the combination omalizumab and HDM - allergen immunotherapy in asthma
CONCLUSION: The combination of HDM SCIT and omalizumab is significantly and progressively reducing ICS use and AX in a 24-month study. The combination is significantly more effective than the single treatments or placebo.PMID:38064236 | DOI:10.1080/02770903.2023.2293057 (Source: Journal of Asthma)
Source: Journal of Asthma - December 8, 2023 Category: Respiratory Medicine Authors: Andrzej Bozek Barbara Rogala Martyna Miodonska Giorgio Walter Canonica Source Type: research
Assessing the risk of intentional self-harm in montelukast users: an updated Sentinel System analysis using ICD-10 coding
CONCLUSION: Our results cannot exclude other neuropsychiatric idiosyncratic reactions to montelukast. Compared to the previous Sentinel study, this study identified about double the rate of self-harm events, suggesting a greater sensitivity of ICD-10 codes for measuring self-harm than ICD-9.PMID:38064517 | DOI:10.1080/02770903.2023.2293064 (Source: Journal of Asthma)
Source: Journal of Asthma - December 8, 2023 Category: Respiratory Medicine Authors: Jummai Apata Jennifer G Lyons Marie C Bradley Yong Ma Maria E Kempner Ivone Kim Efe Eworuke Dinci Pennap Andrew Mosholder Source Type: research
The Role of ACT Score in Mepolizumab Discontinuation
CONCLUSION: In this real-world study, we find that high eosinophil count may not be adequate in screening which individuals will benefit from mepolizumab. Up to 17% of patients fail therapy within 6 months, with male sex and low ACT score increasing risk of mepolizumab discontinuation at Cleveland Clinic.PMID:38064231 | DOI:10.1080/02770903.2023.2293067 (Source: Journal of Asthma)
Source: Journal of Asthma - December 8, 2023 Category: Respiratory Medicine Authors: Neha Solanki Brittany Beck Monica Labadia Kevin Smith Laura Peterson Stephanie King Sarah Micklewright Emily Pennington Sobia Farooq Peng Zhang Mark Aronica Joe Zein Sumita Khatri Suzy Comhair Serpil Erzurum Source Type: research
Progressive clinical effects of the combination omalizumab and HDM - allergen immunotherapy in asthma
CONCLUSION: The combination of HDM SCIT and omalizumab is significantly and progressively reducing ICS use and AX in a 24-month study. The combination is significantly more effective than the single treatments or placebo.PMID:38064236 | DOI:10.1080/02770903.2023.2293057 (Source: Journal of Asthma)
Source: Journal of Asthma - December 8, 2023 Category: Respiratory Medicine Authors: Andrzej Bozek Barbara Rogala Martyna Miodonska Giorgio Walter Canonica Source Type: research
Assessing the risk of intentional self-harm in montelukast users: an updated Sentinel System analysis using ICD-10 coding
CONCLUSION: Our results cannot exclude other neuropsychiatric idiosyncratic reactions to montelukast. Compared to the previous Sentinel study, this study identified about double the rate of self-harm events, suggesting a greater sensitivity of ICD-10 codes for measuring self-harm than ICD-9.PMID:38064517 | DOI:10.1080/02770903.2023.2293064 (Source: Journal of Asthma)
Source: Journal of Asthma - December 8, 2023 Category: Respiratory Medicine Authors: Jummai Apata Jennifer G Lyons Marie C Bradley Yong Ma Maria E Kempner Ivone Kim Efe Eworuke Dinci Pennap Andrew Mosholder Source Type: research
Characteristics of asthma in an older adult population according to sex and control level: Why are asthma symptoms in older women not well-controlled?
CONCLUSION: Herein, older adults comprised 11.5% of adult patients with asthma. Being female poses a disadvantage in terms of both asthma prevalence and control in the older adult asthmatic population owing to the prevalence of comorbidities and socioeconomic sex-related distinguishing factors.PMID:38060588 | DOI:10.1080/02770903.2023.2293062 (Source: Journal of Asthma)
Source: Journal of Asthma - December 7, 2023 Category: Respiratory Medicine Authors: Dilek Karado ğan Elif Y ılmazel Uçar Yasemin Yavuz Ayse Baccioglu Ay şe Bilge Öztürk Nurg ül Bozkurt Murat Kavas Selen Karao ğlanoğlu TAAR Study Group G ülfem Çelik Source Type: research
