Deep Vein Thrombosis and Healing Outcomes in Patients With Pyoderma Gangrenosum
This single-center prospective case-control study assessed the association between deep vein thrombosis and healing outcomes in patients with pyoderma gangrenosum. (Source: JAMA Dermatology)
Source: JAMA Dermatology - February 14, 2024 Category: Dermatology Source Type: research
Balancing Ertapenem Therapy in Recalcitrant Hidradenitis Suppurativa With Antibiotic Stewardship
Hidradenitis suppurativa (HS) is an often-overlooked, painful inflammatory condition associated with substantial physical, psychological, and social impairments, profoundly affecting the quality of life for individuals with the condition. The progress of drug development for HS has been impeded, partly due to a limited understanding of the condition. Despite 2 HS treatments approved by the US Food and Drug Administration and various off-label options, a uniformly effective therapeutic solution for HS remains elusive. (Source: JAMA Dermatology)
Source: JAMA Dermatology - February 14, 2024 Category: Dermatology Source Type: research
Errors in Abstract, Results, Tables, and Figures
This article has been corr ected online. (Source: JAMA Dermatology)
Source: JAMA Dermatology - February 14, 2024 Category: Dermatology Source Type: research
Clinical, Histologic, and Transcriptomic Evaluation of Sequential Fat Grafting for Morphea
This nonrandomized trial examines the antisclerotic and regenerative effects of sequential fat grafting with fresh fat and cryopreserved stromal vascular fraction gel for morphea. (Source: JAMA Dermatology)
Source: JAMA Dermatology - February 7, 2024 Category: Dermatology Source Type: research
Federated Learning for Decentralized Artificial Intelligence in Melanoma Diagnostics
This diagnostic study investigates the performance of a privacy-preserving federated learning approach vs a classical centralized and ensemble learning approach for artificial intelligence –based melanoma diagnostics. (Source: JAMA Dermatology)
Source: JAMA Dermatology - February 7, 2024 Category: Dermatology Source Type: research
Support Group Participation Among Patients With Alopecia Areata
This cross-sectional study describes support group use and experience among patients with alopecia areata. (Source: JAMA Dermatology)
Source: JAMA Dermatology - February 7, 2024 Category: Dermatology Source Type: research
The Promise and Drawbacks of Federated Learning for Dermatology AI
Artificial intelligence (AI) classification of images has achieved considerable promise for dermatology applications for photography, dermoscopy, and pathology for a number of years. However, a major challenge in these arenas is the curation of well-labeled data sets that can be shared publicly due to regulatory concerns as well as the common practice of using retrospective data sets that have not been prospectively consented for research use. AI algorithm performance is directly related to the size and breadth of the data used for training, so methodology that expands the potential size and diversity of inputs and evaluat...
Source: JAMA Dermatology - February 7, 2024 Category: Dermatology Source Type: research
The Alopecia Areata Severity and Morbidity Index (ASAMI) Study
This preliminary global consensus survey study identifies factors associated with alopecia areata severity beyond scalp hair loss, supporting the development of a multicomponent severity tool that would successfully measure various disease outcomes. (Source: JAMA Dermatology)
Source: JAMA Dermatology - February 7, 2024 Category: Dermatology Source Type: research
Persistent Hyperkeratotic Plaques on a Man ’s Genitogluteal Area
A man in his 40s presented with a 10-year history of pruritic lesions on the scrotum and buttock. What is your diagnosis? (Source: JAMA Dermatology)
Source: JAMA Dermatology - February 7, 2024 Category: Dermatology Source Type: research
Potential Role of Tranexamic Acid and Nonablative Fractional Resurfacing in Managing Facial Hyperpigmentation —Reply
In Reply We thank Hashemi et al for their engagement and thoughtful reply to our article that highlighted their experience with tranexamic acid (TA) and procedural therapies. We agree that treatment approaches in hyperpigmentation have had great advancements. We also recognize that tranexamic acid offers an additional option for treating melasma, as we discussed in our article. However, more guidance is needed on optimal therapeutic ranges, dosing regimens, length of treatment, and effects on certain patient populations, such as those receiving hormonal treatments and/or with hypercoagulable disorders. While TA has a promi...
Source: JAMA Dermatology - February 1, 2024 Category: Dermatology Source Type: research
Potential Role of Tranexamic Acid and Nonablative Fractional Resurfacing in Managing Facial Hyperpigmentation
To the Editor In reading the recent article by Kundu et al regarding the management of facial hyperpigmentation due to melasma and postinflammatory hyperpigmentation (PIH), we have additional perspectives regarding medical and procedural management given recent advancements described in the literature and our own clinical experience. Regarding medical management, several recent studies have supported the effectiveness and safety of oral tranexamic acid (TA) in treating various pigmentary disorders, such as melasma and PIH. Despite its historical hemostatic indications at higher doses, multiple studies have demonstrated low...
Source: JAMA Dermatology - February 1, 2024 Category: Dermatology Source Type: research
JAMA Dermatology
Mission Statement: JAMA Dermatology’s mission is to elevate the art and science of health and diseases of skin, hair, nails, and mucous membranes, and their treatment, to enable dermatologists to deliver evidence-based, high-value medical and surgical dermatologic care. The journal publishes a broad range of inn ovative studies and trials that shift research and clinical practice paradigms, expand the understanding of the burden of dermatologic diseases and key outcomes, improve the practice of dermatology, and ensure equitable care to all patients. The journal also features research and opinion examining e thical, m...
Source: JAMA Dermatology - February 1, 2024 Category: Dermatology Source Type: research
Estimated Spending on Beremagene Geperpavec for Dystrophic Epidermolysis Bullosa
This economic evaluation estimates US spending on beremagene geperpavec for treating dystrophic epidermolysis bullosa under varying assumptions of cost, the eligible patient population, patient age at diagnosis, and life expectancy. (Source: JAMA Dermatology)
Source: JAMA Dermatology - January 31, 2024 Category: Dermatology Source Type: research
Meta-Analysis of the Safety of JAK-STAT inhibitors in Dermatology
This systematic review with meta-analysis examines the risk of major adverse cardiovascular events, venous thromboembolism, serious adverse events, and tolerability of systemic Janus kinase –signal transducer and activation of transcription (JAK-STAT) compared with placebo in those with a dermatologic indication. (Source: JAMA Dermatology)
Source: JAMA Dermatology - January 31, 2024 Category: Dermatology Source Type: research
Full-Body Skin Examinations Among Sexual and Gender Minority Patients
This survey study assesses full-body skin examination rates among sexual and gender minority patients and investigates their comfort with and reasons for discomfort during these examinations. (Source: JAMA Dermatology)
Source: JAMA Dermatology - January 31, 2024 Category: Dermatology Source Type: research
